Strain Fitness in Azospirillum sp. SherDot2 around MPMX19_06206

Experiment: NL-CCM, start OD=0.1

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntMPMX19_06205 and MPMX19_06206 are separated by 191 nucleotidesMPMX19_06206 and MPMX19_06207 are separated by 388 nucleotidesMPMX19_06207 and MPMX19_06208 are separated by 114 nucleotides MPMX19_06205: MPMX19_06205 - hypothetical protein, at 391,220 to 392,464 _06205 MPMX19_06206: MPMX19_06206 - Cell cycle response regulator CtrA, at 392,656 to 393,468 _06206 MPMX19_06207: MPMX19_06207 - hypothetical protein, at 393,857 to 394,300 _06207 MPMX19_06208: MPMX19_06208 - tRNA-Val, at 394,415 to 394,489 _06208 Position (kb) 392 393 394Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 391.734 kb on + strand, within MPMX19_06205at 391.734 kb on + strand, within MPMX19_06205at 391.734 kb on + strand, within MPMX19_06205at 391.734 kb on + strand, within MPMX19_06205at 391.734 kb on + strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.735 kb on - strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.968 kb on + strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 391.969 kb on - strand, within MPMX19_06205at 392.052 kb on + strand, within MPMX19_06205at 392.052 kb on + strand, within MPMX19_06205at 392.052 kb on + strand, within MPMX19_06205at 392.052 kb on + strand, within MPMX19_06205at 392.052 kb on + strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.053 kb on - strand, within MPMX19_06205at 392.328 kb on + strand, within MPMX19_06205at 392.328 kb on + strand, within MPMX19_06205at 392.329 kb on - strand, within MPMX19_06205at 392.329 kb on - strand, within MPMX19_06205at 392.452 kb on + strandat 392.452 kb on + strandat 392.452 kb on + strandat 392.452 kb on + strandat 392.452 kb on + strandat 392.452 kb on + strandat 392.452 kb on + strandat 392.453 kb on - strandat 392.453 kb on - strandat 392.453 kb on - strandat 392.453 kb on - strandat 392.468 kb on + strandat 392.468 kb on + strandat 392.468 kb on + strandat 392.468 kb on + strandat 392.469 kb on - strandat 392.469 kb on - strandat 392.469 kb on - strandat 392.469 kb on - strandat 392.583 kb on + strandat 392.583 kb on + strandat 392.583 kb on + strandat 392.584 kb on - strandat 392.584 kb on - strandat 392.807 kb on + strand, within MPMX19_06206at 392.808 kb on - strand, within MPMX19_06206at 392.808 kb on - strand, within MPMX19_06206at 392.808 kb on - strand, within MPMX19_06206at 392.819 kb on + strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.820 kb on - strand, within MPMX19_06206at 392.834 kb on + strand, within MPMX19_06206at 392.834 kb on + strand, within MPMX19_06206at 392.834 kb on + strand, within MPMX19_06206at 392.834 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.883 kb on + strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.884 kb on - strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.885 kb on + strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.886 kb on - strand, within MPMX19_06206at 392.930 kb on + strand, within MPMX19_06206at 392.930 kb on + strand, within MPMX19_06206at 392.931 kb on - strand, within MPMX19_06206at 392.942 kb on + strand, within MPMX19_06206at 392.942 kb on + strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 392.943 kb on - strand, within MPMX19_06206at 393.107 kb on + strand, within MPMX19_06206at 393.107 kb on + strand, within MPMX19_06206at 393.107 kb on + strand, within MPMX19_06206at 393.107 kb on + strand, within MPMX19_06206at 393.108 kb on - strand, within MPMX19_06206at 393.394 kb on - strandat 393.394 kb on - strandat 393.498 kb on + strandat 393.499 kb on - strandat 393.499 kb on - strandat 393.499 kb on - strandat 393.574 kb on + strandat 393.601 kb on - strandat 393.601 kb on - strandat 393.606 kb on + strandat 393.606 kb on + strandat 393.606 kb on + strandat 393.607 kb on - strandat 393.624 kb on + strandat 393.625 kb on - strandat 393.635 kb on - strandat 393.635 kb on - strandat 393.648 kb on + strandat 393.651 kb on + strandat 393.687 kb on - strandat 393.734 kb on + strandat 393.734 kb on + strandat 393.735 kb on - strandat 393.735 kb on - strandat 393.750 kb on + strandat 393.750 kb on + strandat 393.750 kb on + strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.751 kb on - strandat 393.788 kb on + strandat 393.788 kb on + strandat 393.788 kb on + strandat 393.788 kb on + strandat 393.789 kb on - strandat 393.789 kb on - strandat 393.809 kb on - strandat 393.822 kb on + strandat 393.822 kb on + strandat 393.822 kb on + strandat 393.822 kb on + strandat 393.822 kb on + strandat 393.822 kb on + strandat 393.823 kb on - strandat 393.823 kb on - strandat 393.823 kb on - strandat 393.823 kb on - strandat 393.823 kb on - strandat 394.034 kb on + strand, within MPMX19_06207at 394.034 kb on + strand, within MPMX19_06207at 394.034 kb on + strand, within MPMX19_06207at 394.047 kb on - strand, within MPMX19_06207at 394.047 kb on - strand, within MPMX19_06207at 394.160 kb on + strand, within MPMX19_06207at 394.160 kb on + strand, within MPMX19_06207at 394.160 kb on + strand, within MPMX19_06207at 394.161 kb on - strand, within MPMX19_06207

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction NL-CCM, start OD=0.1
remove
391,734 + MPMX19_06205 0.41 +1.0
391,734 + MPMX19_06205 0.41 +1.7
391,734 + MPMX19_06205 0.41 +0.8
391,734 + MPMX19_06205 0.41 -0.1
391,734 + MPMX19_06205 0.41 +0.9
391,735 - MPMX19_06205 0.41 -0.8
391,735 - MPMX19_06205 0.41 -0.5
391,735 - MPMX19_06205 0.41 +0.7
391,735 - MPMX19_06205 0.41 -0.2
391,735 - MPMX19_06205 0.41 -0.2
391,735 - MPMX19_06205 0.41 -0.8
391,968 + MPMX19_06205 0.60 -0.0
391,968 + MPMX19_06205 0.60 -0.5
391,968 + MPMX19_06205 0.60 -0.2
391,968 + MPMX19_06205 0.60 +0.7
391,968 + MPMX19_06205 0.60 -1.9
391,968 + MPMX19_06205 0.60 -1.1
391,968 + MPMX19_06205 0.60 -0.7
391,968 + MPMX19_06205 0.60 -3.3
391,968 + MPMX19_06205 0.60 +0.9
391,968 + MPMX19_06205 0.60 +0.3
391,968 + MPMX19_06205 0.60 +1.2
391,968 + MPMX19_06205 0.60 +0.2
391,968 + MPMX19_06205 0.60 +1.7
391,968 + MPMX19_06205 0.60 +0.0
391,968 + MPMX19_06205 0.60 -0.2
391,968 + MPMX19_06205 0.60 +2.0
391,969 - MPMX19_06205 0.60 -0.1
391,969 - MPMX19_06205 0.60 -0.9
391,969 - MPMX19_06205 0.60 +0.2
391,969 - MPMX19_06205 0.60 -0.6
391,969 - MPMX19_06205 0.60 -0.3
391,969 - MPMX19_06205 0.60 -0.6
391,969 - MPMX19_06205 0.60 -0.5
391,969 - MPMX19_06205 0.60 -0.1
392,052 + MPMX19_06205 0.67 -0.7
392,052 + MPMX19_06205 0.67 -1.3
392,052 + MPMX19_06205 0.67 -0.6
392,052 + MPMX19_06205 0.67 -0.6
392,052 + MPMX19_06205 0.67 -0.0
392,053 - MPMX19_06205 0.67 +0.5
392,053 - MPMX19_06205 0.67 -0.3
392,053 - MPMX19_06205 0.67 -0.6
392,053 - MPMX19_06205 0.67 +0.6
392,053 - MPMX19_06205 0.67 +0.1
392,053 - MPMX19_06205 0.67 -0.9
392,053 - MPMX19_06205 0.67 -0.0
392,053 - MPMX19_06205 0.67 +1.7
392,053 - MPMX19_06205 0.67 +0.7
392,053 - MPMX19_06205 0.67 +1.0
392,328 + MPMX19_06205 0.89 -3.8
392,328 + MPMX19_06205 0.89 -0.1
392,329 - MPMX19_06205 0.89 -0.3
392,329 - MPMX19_06205 0.89 +0.4
392,452 + -2.4
392,452 + -0.9
392,452 + -1.1
392,452 + +0.3
392,452 + -0.5
392,452 + -1.1
392,452 + -0.9
392,453 - -0.1
392,453 - -0.9
392,453 - -1.5
392,453 - -1.5
392,468 + +0.1
392,468 + +0.6
392,468 + -0.4
392,468 + -0.9
392,469 - +0.3
392,469 - -1.3
392,469 - +2.0
392,469 - +0.4
392,583 + -1.0
392,583 + -0.0
392,583 + -0.2
392,584 - -0.2
392,584 - +0.7
392,807 + MPMX19_06206 0.19 -0.6
392,808 - MPMX19_06206 0.19 +0.7
392,808 - MPMX19_06206 0.19 -0.5
392,808 - MPMX19_06206 0.19 -1.4
392,819 + MPMX19_06206 0.20 -0.2
392,820 - MPMX19_06206 0.20 -1.5
392,820 - MPMX19_06206 0.20 -0.2
392,820 - MPMX19_06206 0.20 -0.6
392,820 - MPMX19_06206 0.20 -0.8
392,820 - MPMX19_06206 0.20 -0.0
392,820 - MPMX19_06206 0.20 -0.6
392,820 - MPMX19_06206 0.20 -0.1
392,834 + MPMX19_06206 0.22 -0.3
392,834 + MPMX19_06206 0.22 -0.6
392,834 + MPMX19_06206 0.22 +1.0
392,834 + MPMX19_06206 0.22 +1.0
392,883 + MPMX19_06206 0.28 -0.2
392,883 + MPMX19_06206 0.28 -1.3
392,883 + MPMX19_06206 0.28 -0.2
392,883 + MPMX19_06206 0.28 -1.0
392,883 + MPMX19_06206 0.28 -1.5
392,883 + MPMX19_06206 0.28 +0.6
392,883 + MPMX19_06206 0.28 +0.4
392,883 + MPMX19_06206 0.28 +0.1
392,883 + MPMX19_06206 0.28 +0.3
392,883 + MPMX19_06206 0.28 -0.8
392,883 + MPMX19_06206 0.28 +0.4
392,883 + MPMX19_06206 0.28 -0.2
392,883 + MPMX19_06206 0.28 -0.6
392,883 + MPMX19_06206 0.28 -0.3
392,883 + MPMX19_06206 0.28 +0.2
392,883 + MPMX19_06206 0.28 -1.1
392,883 + MPMX19_06206 0.28 -0.2
392,883 + MPMX19_06206 0.28 +0.1
392,883 + MPMX19_06206 0.28 +0.3
392,884 - MPMX19_06206 0.28 -0.1
392,884 - MPMX19_06206 0.28 -0.3
392,884 - MPMX19_06206 0.28 +1.1
392,884 - MPMX19_06206 0.28 +1.3
392,884 - MPMX19_06206 0.28 +0.2
392,884 - MPMX19_06206 0.28 -0.6
392,884 - MPMX19_06206 0.28 +0.5
392,884 - MPMX19_06206 0.28 -0.4
392,885 + MPMX19_06206 0.28 -0.0
392,885 + MPMX19_06206 0.28 -0.1
392,885 + MPMX19_06206 0.28 -0.7
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -1.1
392,885 + MPMX19_06206 0.28 -0.6
392,885 + MPMX19_06206 0.28 -0.8
392,885 + MPMX19_06206 0.28 -1.1
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -2.1
392,885 + MPMX19_06206 0.28 -0.5
392,885 + MPMX19_06206 0.28 +0.2
392,885 + MPMX19_06206 0.28 -0.5
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -0.6
392,885 + MPMX19_06206 0.28 -2.6
392,885 + MPMX19_06206 0.28 -0.1
392,885 + MPMX19_06206 0.28 +0.1
392,885 + MPMX19_06206 0.28 +0.0
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -1.3
392,885 + MPMX19_06206 0.28 -2.1
392,885 + MPMX19_06206 0.28 +1.6
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -0.3
392,885 + MPMX19_06206 0.28 -0.4
392,885 + MPMX19_06206 0.28 -0.6
392,886 - MPMX19_06206 0.28 +0.3
392,886 - MPMX19_06206 0.28 +0.7
392,886 - MPMX19_06206 0.28 -0.9
392,886 - MPMX19_06206 0.28 +0.8
392,886 - MPMX19_06206 0.28 -0.3
392,886 - MPMX19_06206 0.28 -0.6
392,886 - MPMX19_06206 0.28 -2.4
392,886 - MPMX19_06206 0.28 -0.5
392,886 - MPMX19_06206 0.28 +0.0
392,886 - MPMX19_06206 0.28 -0.6
392,886 - MPMX19_06206 0.28 +0.6
392,886 - MPMX19_06206 0.28 -0.0
392,886 - MPMX19_06206 0.28 +0.9
392,886 - MPMX19_06206 0.28 +1.7
392,886 - MPMX19_06206 0.28 -1.6
392,886 - MPMX19_06206 0.28 +0.4
392,886 - MPMX19_06206 0.28 -3.1
392,886 - MPMX19_06206 0.28 -0.1
392,886 - MPMX19_06206 0.28 -0.3
392,886 - MPMX19_06206 0.28 +0.5
392,886 - MPMX19_06206 0.28 -0.2
392,886 - MPMX19_06206 0.28 -1.1
392,886 - MPMX19_06206 0.28 -0.1
392,886 - MPMX19_06206 0.28 -0.1
392,930 + MPMX19_06206 0.34 +0.3
392,930 + MPMX19_06206 0.34 -0.7
392,931 - MPMX19_06206 0.34 +0.6
392,942 + MPMX19_06206 0.35 +1.0
392,942 + MPMX19_06206 0.35 -0.5
392,943 - MPMX19_06206 0.35 +1.1
392,943 - MPMX19_06206 0.35 -1.3
392,943 - MPMX19_06206 0.35 -1.3
392,943 - MPMX19_06206 0.35 -0.5
392,943 - MPMX19_06206 0.35 -0.6
392,943 - MPMX19_06206 0.35 -0.5
392,943 - MPMX19_06206 0.35 +1.0
392,943 - MPMX19_06206 0.35 +0.4
392,943 - MPMX19_06206 0.35 -1.6
392,943 - MPMX19_06206 0.35 +0.0
393,107 + MPMX19_06206 0.55 +0.1
393,107 + MPMX19_06206 0.55 -0.7
393,107 + MPMX19_06206 0.55 +0.0
393,107 + MPMX19_06206 0.55 +0.6
393,108 - MPMX19_06206 0.56 -1.1
393,394 - -0.0
393,394 - +1.7
393,498 + +0.7
393,499 - -1.5
393,499 - -0.9
393,499 - -0.9
393,574 + -1.4
393,601 - -0.9
393,601 - -0.9
393,606 + -0.0
393,606 + -0.4
393,606 + -1.5
393,607 - -1.1
393,624 + -1.5
393,625 - -0.2
393,635 - -0.0
393,635 - -1.5
393,648 + +0.1
393,651 + -0.7
393,687 - -1.4
393,734 + -0.9
393,734 + +0.5
393,735 - -1.0
393,735 - -0.6
393,750 + -1.1
393,750 + -0.3
393,750 + -0.7
393,751 - -1.8
393,751 - +0.3
393,751 - +0.7
393,751 - -0.4
393,751 - +0.9
393,751 - -1.0
393,751 - -2.5
393,788 + -1.7
393,788 + -0.3
393,788 + +0.2
393,788 + -0.0
393,789 - -2.5
393,789 - +0.9
393,809 - -1.7
393,822 + +0.3
393,822 + -0.2
393,822 + -0.2
393,822 + -0.7
393,822 + -2.1
393,822 + -1.1
393,823 - +0.5
393,823 - -1.0
393,823 - -0.9
393,823 - -1.5
393,823 - -1.6
394,034 + MPMX19_06207 0.40 -0.5
394,034 + MPMX19_06207 0.40 -0.1
394,034 + MPMX19_06207 0.40 +0.9
394,047 - MPMX19_06207 0.43 +0.1
394,047 - MPMX19_06207 0.43 +1.7
394,160 + MPMX19_06207 0.68 -1.0
394,160 + MPMX19_06207 0.68 -0.5
394,160 + MPMX19_06207 0.68 -0.9
394,161 - MPMX19_06207 0.68 -0.2

Or see this region's nucleotide sequence