Strain Fitness in Azospirillum sp. SherDot2 around MPMX19_05637

Experiment: NF

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntMPMX19_05636 and MPMX19_05637 are separated by 350 nucleotidesMPMX19_05637 and MPMX19_05638 overlap by 4 nucleotides MPMX19_05636: MPMX19_05636 - hypothetical protein, at 353,292 to 355,067 _05636 MPMX19_05637: MPMX19_05637 - Adaptive-response sensory-kinase SasA, at 355,418 to 357,637 _05637 MPMX19_05638: MPMX19_05638 - Aerobic respiration control protein ArcA, at 357,634 to 358,458 _05638 Position (kb) 355 356 357 358Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 354.493 kb on + strand, within MPMX19_05636at 354.493 kb on + strand, within MPMX19_05636at 354.493 kb on + strand, within MPMX19_05636at 354.493 kb on + strand, within MPMX19_05636at 354.493 kb on + strand, within MPMX19_05636at 354.494 kb on - strand, within MPMX19_05636at 354.628 kb on + strand, within MPMX19_05636at 354.629 kb on - strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.640 kb on + strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.641 kb on - strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.646 kb on + strand, within MPMX19_05636at 354.647 kb on - strand, within MPMX19_05636at 354.647 kb on - strand, within MPMX19_05636at 354.647 kb on - strand, within MPMX19_05636at 354.647 kb on - strand, within MPMX19_05636at 354.676 kb on + strand, within MPMX19_05636at 354.676 kb on + strand, within MPMX19_05636at 354.676 kb on + strand, within MPMX19_05636at 354.677 kb on - strand, within MPMX19_05636at 354.677 kb on - strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.715 kb on + strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.716 kb on - strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.742 kb on + strand, within MPMX19_05636at 354.743 kb on - strand, within MPMX19_05636at 354.743 kb on - strand, within MPMX19_05636at 354.841 kb on + strand, within MPMX19_05636at 354.841 kb on + strand, within MPMX19_05636at 354.842 kb on - strand, within MPMX19_05636at 354.842 kb on - strand, within MPMX19_05636at 354.842 kb on - strand, within MPMX19_05636at 354.898 kb on + strandat 354.899 kb on - strandat 354.899 kb on - strandat 354.941 kb on + strandat 354.942 kb on - strandat 354.942 kb on - strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.943 kb on + strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.944 kb on - strandat 354.952 kb on + strandat 354.952 kb on + strandat 354.952 kb on + strandat 354.952 kb on + strandat 354.952 kb on + strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 354.953 kb on - strandat 355.125 kb on - strandat 355.125 kb on - strandat 355.135 kb on + strandat 355.164 kb on + strandat 355.164 kb on + strandat 355.190 kb on + strandat 355.201 kb on + strandat 355.202 kb on - strandat 355.202 kb on - strandat 355.313 kb on - strandat 355.364 kb on + strandat 355.364 kb on + strandat 355.364 kb on + strandat 355.365 kb on - strandat 355.365 kb on - strandat 355.365 kb on - strandat 355.462 kb on - strandat 355.462 kb on - strandat 355.823 kb on + strand, within MPMX19_05637at 355.823 kb on + strand, within MPMX19_05637at 355.824 kb on - strand, within MPMX19_05637at 355.824 kb on - strand, within MPMX19_05637at 355.824 kb on - strand, within MPMX19_05637at 355.824 kb on - strand, within MPMX19_05637at 355.824 kb on - strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.844 kb on + strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.845 kb on - strand, within MPMX19_05637at 355.907 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.156 kb on + strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.157 kb on - strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.174 kb on + strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.175 kb on - strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.420 kb on + strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.421 kb on - strand, within MPMX19_05637at 356.618 kb on + strand, within MPMX19_05637at 356.619 kb on - strand, within MPMX19_05637at 356.619 kb on - strand, within MPMX19_05637at 356.885 kb on + strand, within MPMX19_05637at 356.885 kb on + strand, within MPMX19_05637at 356.886 kb on - strand, within MPMX19_05637at 356.950 kb on + strand, within MPMX19_05637at 356.950 kb on + strand, within MPMX19_05637at 356.951 kb on - strand, within MPMX19_05637at 357.302 kb on + strand, within MPMX19_05637at 357.302 kb on + strand, within MPMX19_05637at 357.302 kb on + strand, within MPMX19_05637at 357.745 kb on + strand, within MPMX19_05638at 357.745 kb on + strand, within MPMX19_05638at 357.745 kb on + strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.746 kb on - strand, within MPMX19_05638at 357.810 kb on - strand, within MPMX19_05638at 357.822 kb on + strand, within MPMX19_05638at 357.979 kb on + strand, within MPMX19_05638at 357.979 kb on + strand, within MPMX19_05638at 357.979 kb on + strand, within MPMX19_05638at 357.979 kb on + strand, within MPMX19_05638at 357.979 kb on + strand, within MPMX19_05638at 357.980 kb on - strand, within MPMX19_05638at 357.980 kb on - strand, within MPMX19_05638at 357.980 kb on - strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.334 kb on + strand, within MPMX19_05638at 358.335 kb on - strand, within MPMX19_05638at 358.335 kb on - strand, within MPMX19_05638at 358.335 kb on - strand, within MPMX19_05638at 358.335 kb on - strand, within MPMX19_05638at 358.335 kb on - strand, within MPMX19_05638at 358.502 kb on + strandat 358.609 kb on - strandat 358.609 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction NF
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354,493 + MPMX19_05636 0.68 -0.0
354,493 + MPMX19_05636 0.68 -1.1
354,493 + MPMX19_05636 0.68 +1.0
354,493 + MPMX19_05636 0.68 -0.5
354,493 + MPMX19_05636 0.68 -0.8
354,494 - MPMX19_05636 0.68 -1.1
354,628 + MPMX19_05636 0.75 +0.2
354,629 - MPMX19_05636 0.75 -0.6
354,640 + MPMX19_05636 0.76 -1.0
354,640 + MPMX19_05636 0.76 +0.1
354,640 + MPMX19_05636 0.76 +0.6
354,640 + MPMX19_05636 0.76 -1.5
354,640 + MPMX19_05636 0.76 -0.8
354,640 + MPMX19_05636 0.76 -0.6
354,641 - MPMX19_05636 0.76 -0.9
354,641 - MPMX19_05636 0.76 -0.9
354,641 - MPMX19_05636 0.76 +0.7
354,641 - MPMX19_05636 0.76 -0.6
354,641 - MPMX19_05636 0.76 -1.2
354,641 - MPMX19_05636 0.76 +0.3
354,641 - MPMX19_05636 0.76 +0.1
354,646 + MPMX19_05636 0.76 -1.2
354,646 + MPMX19_05636 0.76 -0.4
354,646 + MPMX19_05636 0.76 -0.1
354,646 + MPMX19_05636 0.76 -1.5
354,646 + MPMX19_05636 0.76 -0.4
354,646 + MPMX19_05636 0.76 -0.2
354,647 - MPMX19_05636 0.76 +0.3
354,647 - MPMX19_05636 0.76 -0.3
354,647 - MPMX19_05636 0.76 -0.1
354,647 - MPMX19_05636 0.76 -0.3
354,676 + MPMX19_05636 0.78 +0.6
354,676 + MPMX19_05636 0.78 +0.2
354,676 + MPMX19_05636 0.78 -0.8
354,677 - MPMX19_05636 0.78 +0.1
354,677 - MPMX19_05636 0.78 -0.3
354,715 + MPMX19_05636 0.80 +0.8
354,715 + MPMX19_05636 0.80 -0.5
354,715 + MPMX19_05636 0.80 +1.4
354,715 + MPMX19_05636 0.80 -0.9
354,715 + MPMX19_05636 0.80 -2.2
354,715 + MPMX19_05636 0.80 -0.5
354,716 - MPMX19_05636 0.80 -0.3
354,716 - MPMX19_05636 0.80 -0.8
354,716 - MPMX19_05636 0.80 -0.0
354,716 - MPMX19_05636 0.80 -0.7
354,716 - MPMX19_05636 0.80 -0.0
354,716 - MPMX19_05636 0.80 -0.3
354,742 + MPMX19_05636 0.82 -1.5
354,742 + MPMX19_05636 0.82 +0.7
354,742 + MPMX19_05636 0.82 -0.2
354,742 + MPMX19_05636 0.82 +0.4
354,742 + MPMX19_05636 0.82 +1.2
354,742 + MPMX19_05636 0.82 -1.1
354,742 + MPMX19_05636 0.82 -1.1
354,743 - MPMX19_05636 0.82 +2.2
354,743 - MPMX19_05636 0.82 -1.6
354,841 + MPMX19_05636 0.87 -0.6
354,841 + MPMX19_05636 0.87 +0.4
354,842 - MPMX19_05636 0.87 +0.2
354,842 - MPMX19_05636 0.87 +0.3
354,842 - MPMX19_05636 0.87 -0.3
354,898 + -1.6
354,899 - -0.6
354,899 - +0.4
354,941 + +0.7
354,942 - -0.8
354,942 - +0.8
354,943 + +1.4
354,943 + +0.4
354,943 + +0.2
354,943 + -0.8
354,943 + +0.8
354,943 + -0.3
354,943 + +0.4
354,943 + -0.6
354,944 - +2.0
354,944 - +0.2
354,944 - -0.2
354,944 - -1.7
354,944 - -1.2
354,944 - -0.1
354,944 - -0.0
354,944 - +1.3
354,944 - -0.6
354,944 - -0.2
354,952 + -0.3
354,952 + +0.8
354,952 + -0.0
354,952 + -0.3
354,952 + +1.5
354,953 - -0.6
354,953 - +0.2
354,953 - -0.1
354,953 - -1.1
354,953 - +0.3
354,953 - -0.8
354,953 - -0.7
354,953 - -1.5
354,953 - -0.5
355,125 - +1.3
355,125 - -0.0
355,135 + -0.2
355,164 + -0.1
355,164 + -1.6
355,190 + -0.2
355,201 + -1.5
355,202 - +0.1
355,202 - +0.8
355,313 - -2.2
355,364 + -0.1
355,364 + -0.7
355,364 + -0.2
355,365 - -0.5
355,365 - -0.8
355,365 - +0.8
355,462 - -0.8
355,462 - +0.6
355,823 + MPMX19_05637 0.18 +0.3
355,823 + MPMX19_05637 0.18 -0.1
355,824 - MPMX19_05637 0.18 -1.2
355,824 - MPMX19_05637 0.18 -0.6
355,824 - MPMX19_05637 0.18 -1.3
355,824 - MPMX19_05637 0.18 +1.2
355,824 - MPMX19_05637 0.18 -1.3
355,844 + MPMX19_05637 0.19 +0.4
355,844 + MPMX19_05637 0.19 -0.8
355,844 + MPMX19_05637 0.19 -0.7
355,844 + MPMX19_05637 0.19 -1.1
355,844 + MPMX19_05637 0.19 -1.5
355,844 + MPMX19_05637 0.19 -0.7
355,844 + MPMX19_05637 0.19 -0.6
355,844 + MPMX19_05637 0.19 +0.1
355,845 - MPMX19_05637 0.19 -0.6
355,845 - MPMX19_05637 0.19 -1.0
355,845 - MPMX19_05637 0.19 -0.5
355,845 - MPMX19_05637 0.19 -0.4
355,845 - MPMX19_05637 0.19 +0.2
355,845 - MPMX19_05637 0.19 -0.3
355,845 - MPMX19_05637 0.19 -0.5
355,845 - MPMX19_05637 0.19 +1.4
355,907 + MPMX19_05637 0.22 +0.8
356,156 + MPMX19_05637 0.33 +0.2
356,156 + MPMX19_05637 0.33 -0.0
356,156 + MPMX19_05637 0.33 -0.6
356,156 + MPMX19_05637 0.33 -0.6
356,156 + MPMX19_05637 0.33 -1.2
356,156 + MPMX19_05637 0.33 -0.7
356,156 + MPMX19_05637 0.33 -0.3
356,156 + MPMX19_05637 0.33 -1.5
356,157 - MPMX19_05637 0.33 -0.6
356,157 - MPMX19_05637 0.33 -1.2
356,157 - MPMX19_05637 0.33 -0.2
356,157 - MPMX19_05637 0.33 -0.2
356,157 - MPMX19_05637 0.33 -0.0
356,157 - MPMX19_05637 0.33 -0.7
356,157 - MPMX19_05637 0.33 -0.6
356,157 - MPMX19_05637 0.33 -0.3
356,157 - MPMX19_05637 0.33 +0.8
356,174 + MPMX19_05637 0.34 -0.0
356,174 + MPMX19_05637 0.34 -0.2
356,174 + MPMX19_05637 0.34 +1.2
356,174 + MPMX19_05637 0.34 +0.1
356,174 + MPMX19_05637 0.34 -1.3
356,174 + MPMX19_05637 0.34 -2.1
356,174 + MPMX19_05637 0.34 -0.7
356,174 + MPMX19_05637 0.34 -0.5
356,174 + MPMX19_05637 0.34 +0.9
356,175 - MPMX19_05637 0.34 -0.7
356,175 - MPMX19_05637 0.34 -0.7
356,175 - MPMX19_05637 0.34 -0.5
356,175 - MPMX19_05637 0.34 -0.5
356,175 - MPMX19_05637 0.34 -0.6
356,175 - MPMX19_05637 0.34 -0.0
356,175 - MPMX19_05637 0.34 +0.8
356,175 - MPMX19_05637 0.34 -0.1
356,175 - MPMX19_05637 0.34 -0.6
356,175 - MPMX19_05637 0.34 -1.0
356,175 - MPMX19_05637 0.34 +0.4
356,420 + MPMX19_05637 0.45 +0.1
356,420 + MPMX19_05637 0.45 -0.6
356,420 + MPMX19_05637 0.45 -1.2
356,420 + MPMX19_05637 0.45 +0.1
356,420 + MPMX19_05637 0.45 -1.5
356,420 + MPMX19_05637 0.45 -0.3
356,420 + MPMX19_05637 0.45 +1.0
356,420 + MPMX19_05637 0.45 -2.0
356,420 + MPMX19_05637 0.45 -2.9
356,421 - MPMX19_05637 0.45 +0.8
356,421 - MPMX19_05637 0.45 +2.3
356,421 - MPMX19_05637 0.45 -1.2
356,421 - MPMX19_05637 0.45 -0.2
356,421 - MPMX19_05637 0.45 -0.6
356,421 - MPMX19_05637 0.45 +0.7
356,421 - MPMX19_05637 0.45 -1.0
356,421 - MPMX19_05637 0.45 +1.4
356,421 - MPMX19_05637 0.45 +0.4
356,421 - MPMX19_05637 0.45 -2.2
356,618 + MPMX19_05637 0.54 +0.2
356,619 - MPMX19_05637 0.54 +0.9
356,619 - MPMX19_05637 0.54 -1.7
356,885 + MPMX19_05637 0.66 -0.2
356,885 + MPMX19_05637 0.66 -1.1
356,886 - MPMX19_05637 0.66 -0.0
356,950 + MPMX19_05637 0.69 +0.7
356,950 + MPMX19_05637 0.69 -0.7
356,951 - MPMX19_05637 0.69 -0.4
357,302 + MPMX19_05637 0.85 +0.1
357,302 + MPMX19_05637 0.85 -0.6
357,302 + MPMX19_05637 0.85 +0.6
357,745 + MPMX19_05638 0.13 -0.3
357,745 + MPMX19_05638 0.13 +1.0
357,745 + MPMX19_05638 0.13 +0.4
357,746 - MPMX19_05638 0.14 -0.3
357,746 - MPMX19_05638 0.14 -1.2
357,746 - MPMX19_05638 0.14 -0.3
357,746 - MPMX19_05638 0.14 -0.2
357,746 - MPMX19_05638 0.14 +1.0
357,746 - MPMX19_05638 0.14 +0.2
357,746 - MPMX19_05638 0.14 -1.0
357,746 - MPMX19_05638 0.14 -0.2
357,810 - MPMX19_05638 0.21 -0.0
357,822 + MPMX19_05638 0.23 -0.1
357,979 + MPMX19_05638 0.42 +0.4
357,979 + MPMX19_05638 0.42 -1.5
357,979 + MPMX19_05638 0.42 -0.6
357,979 + MPMX19_05638 0.42 +1.2
357,979 + MPMX19_05638 0.42 -0.8
357,980 - MPMX19_05638 0.42 -1.3
357,980 - MPMX19_05638 0.42 -1.2
357,980 - MPMX19_05638 0.42 -0.5
358,334 + MPMX19_05638 0.85 +1.2
358,334 + MPMX19_05638 0.85 -0.7
358,334 + MPMX19_05638 0.85 +1.2
358,334 + MPMX19_05638 0.85 -0.3
358,334 + MPMX19_05638 0.85 -1.0
358,334 + MPMX19_05638 0.85 -2.0
358,334 + MPMX19_05638 0.85 -1.3
358,334 + MPMX19_05638 0.85 -0.3
358,335 - MPMX19_05638 0.85 +0.1
358,335 - MPMX19_05638 0.85 +0.2
358,335 - MPMX19_05638 0.85 -1.3
358,335 - MPMX19_05638 0.85 -0.6
358,335 - MPMX19_05638 0.85 +0.1
358,502 + +0.4
358,609 - -0.6
358,609 - -0.6

Or see this region's nucleotide sequence