Experiment: Cisplatin 0.0125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1478 and PfGW456L13_1479 overlap by 8 nucleotides PfGW456L13_1479 and PfGW456L13_1480 are separated by 168 nucleotides PfGW456L13_1480 and PfGW456L13_1481 overlap by 32 nucleotides PfGW456L13_1481 and PfGW456L13_1482 are separated by 130 nucleotides
PfGW456L13_1478 - Lipoprotein signal peptidase (EC 3.4.23.36), at 1,632,442 to 1,632,909
_1478
PfGW456L13_1479 - FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8), at 1,632,902 to 1,633,354
_1479
PfGW456L13_1480 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2), at 1,633,523 to 1,634,470
_1480
PfGW456L13_1481 - Type IV fimbrial biogenesis protein FimT, at 1,634,439 to 1,634,978
_1481
PfGW456L13_1482 - type 4 fimbrial biogenesis protein FimU, at 1,635,109 to 1,635,582
_1482
Position (kb)
1633
1634
1635 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1632.867 kb on + strand at 1632.915 kb on + strand at 1632.915 kb on + strand at 1632.915 kb on + strand at 1633.231 kb on + strand, within PfGW456L13_1479 at 1633.326 kb on + strand at 1633.326 kb on + strand at 1633.326 kb on + strand at 1633.326 kb on + strand at 1633.352 kb on + strand at 1633.352 kb on + strand at 1633.352 kb on + strand at 1633.417 kb on + strand at 1633.431 kb on + strand at 1633.431 kb on + strand at 1633.437 kb on + strand at 1633.437 kb on + strand at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.587 kb on + strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.588 kb on - strand, within PfGW456L13_1481 at 1634.589 kb on + strand, within PfGW456L13_1481 at 1634.590 kb on - strand, within PfGW456L13_1481 at 1634.590 kb on - strand, within PfGW456L13_1481 at 1634.590 kb on - strand, within PfGW456L13_1481 at 1634.631 kb on + strand, within PfGW456L13_1481 at 1634.631 kb on + strand, within PfGW456L13_1481 at 1634.631 kb on + strand, within PfGW456L13_1481 at 1634.835 kb on - strand, within PfGW456L13_1481 at 1634.835 kb on - strand, within PfGW456L13_1481 at 1634.927 kb on + strand at 1634.928 kb on - strand at 1634.967 kb on + strand at 1634.968 kb on - strand at 1634.968 kb on - strand at 1634.968 kb on - strand at 1634.968 kb on - strand at 1634.968 kb on - strand at 1634.968 kb on - strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.082 kb on + strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.083 kb on - strand at 1635.084 kb on + strand at 1635.084 kb on + strand at 1635.084 kb on + strand at 1635.085 kb on - strand at 1635.120 kb on + strand at 1635.120 kb on + strand at 1635.120 kb on + strand at 1635.121 kb on - strand at 1635.121 kb on - strand at 1635.121 kb on - strand at 1635.121 kb on - strand at 1635.121 kb on - strand at 1635.355 kb on + strand, within PfGW456L13_1482 at 1635.363 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.383 kb on + strand, within PfGW456L13_1482 at 1635.384 kb on - strand, within PfGW456L13_1482 at 1635.384 kb on - strand, within PfGW456L13_1482
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.0125 mg/ml remove 1,632,867 + -0.4 1,632,915 + +1.1 1,632,915 + +1.9 1,632,915 + +0.4 1,633,231 + PfGW456L13_1479 0.73 +1.0 1,633,326 + -1.0 1,633,326 + +0.7 1,633,326 + -0.4 1,633,326 + -2.7 1,633,352 + +0.4 1,633,352 + +0.7 1,633,352 + +0.5 1,633,417 + +1.0 1,633,431 + -0.3 1,633,431 + +0.4 1,633,437 + -0.1 1,633,437 + +0.7 1,634,587 + PfGW456L13_1481 0.27 +0.1 1,634,587 + PfGW456L13_1481 0.27 +0.4 1,634,587 + PfGW456L13_1481 0.27 +0.6 1,634,587 + PfGW456L13_1481 0.27 +0.8 1,634,587 + PfGW456L13_1481 0.27 -0.1 1,634,587 + PfGW456L13_1481 0.27 +0.2 1,634,588 - PfGW456L13_1481 0.28 -0.3 1,634,588 - PfGW456L13_1481 0.28 -0.8 1,634,588 - PfGW456L13_1481 0.28 -0.1 1,634,588 - PfGW456L13_1481 0.28 -0.0 1,634,588 - PfGW456L13_1481 0.28 -0.2 1,634,588 - PfGW456L13_1481 0.28 -0.3 1,634,588 - PfGW456L13_1481 0.28 -0.8 1,634,589 + PfGW456L13_1481 0.28 -0.1 1,634,590 - PfGW456L13_1481 0.28 -0.3 1,634,590 - PfGW456L13_1481 0.28 -1.3 1,634,590 - PfGW456L13_1481 0.28 -0.9 1,634,631 + PfGW456L13_1481 0.36 -0.3 1,634,631 + PfGW456L13_1481 0.36 -1.4 1,634,631 + PfGW456L13_1481 0.36 -2.6 1,634,835 - PfGW456L13_1481 0.73 -0.2 1,634,835 - PfGW456L13_1481 0.73 -0.1 1,634,927 + -0.8 1,634,928 - +0.2 1,634,967 + -1.1 1,634,968 - +0.1 1,634,968 - +0.6 1,634,968 - +2.0 1,634,968 - +0.7 1,634,968 - +0.0 1,634,968 - +0.9 1,635,082 + -0.7 1,635,082 + -0.2 1,635,082 + +0.0 1,635,082 + +0.4 1,635,082 + +0.6 1,635,082 + -0.4 1,635,082 + +0.3 1,635,082 + +0.8 1,635,082 + +0.4 1,635,082 + -0.1 1,635,083 - +0.1 1,635,083 - -0.0 1,635,083 - -0.2 1,635,083 - +0.2 1,635,083 - +0.0 1,635,083 - -0.4 1,635,083 - +0.9 1,635,084 + +0.2 1,635,084 + -0.7 1,635,084 + -0.4 1,635,085 - +0.2 1,635,120 + +0.5 1,635,120 + -0.7 1,635,120 + -0.2 1,635,121 - -0.5 1,635,121 - +0.2 1,635,121 - +0.1 1,635,121 - -0.6 1,635,121 - +0.0 1,635,355 + PfGW456L13_1482 0.52 -0.2 1,635,363 + PfGW456L13_1482 0.54 +0.7 1,635,383 + PfGW456L13_1482 0.58 +0.4 1,635,383 + PfGW456L13_1482 0.58 +0.7 1,635,383 + PfGW456L13_1482 0.58 -0.0 1,635,383 + PfGW456L13_1482 0.58 -0.1 1,635,383 + PfGW456L13_1482 0.58 +0.9 1,635,383 + PfGW456L13_1482 0.58 +0.6 1,635,384 - PfGW456L13_1482 0.58 +0.3 1,635,384 - PfGW456L13_1482 0.58 +0.2
Or see this region's nucleotide sequence