Experiment: PYE with CHIR-090 10 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt CCNA_00476 and CCNA_00477 are separated by 380 nucleotides CCNA_00477 and CCNA_00478 are separated by 121 nucleotides CCNA_00478 and CCNA_00479 are separated by 188 nucleotides CCNA_00479 and CCNA_00480 are separated by 68 nucleotides
CCNA_00476: CCNA_00476 - hypothetical protein, at 493,326 to 493,709
_00476
CCNA_00477: CCNA_00477 - excisionase, at 494,090 to 494,284
_00477
CCNA_00478: CCNA_00478 - hypothetical protein, at 494,406 to 495,143
_00478
CCNA_00479: CCNA_00479 - Helix-turn-helix DNA-binding protein, at 495,332 to 495,655
_00479
CCNA_00480: CCNA_00480 - bacteriophage P4 integrase, at 495,724 to 497,022
_00480
Position (kb) 494
495
496 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 493.429 kb on + strand, within CCNA_00476 at 493.429 kb on + strand, within CCNA_00476 at 493.446 kb on + strand, within CCNA_00476 at 493.446 kb on + strand, within CCNA_00476 at 493.446 kb on + strand, within CCNA_00476 at 493.446 kb on + strand, within CCNA_00476 at 493.454 kb on - strand, within CCNA_00476 at 493.462 kb on + strand, within CCNA_00476 at 493.512 kb on - strand, within CCNA_00476 at 493.520 kb on + strand, within CCNA_00476 at 493.528 kb on - strand, within CCNA_00476 at 493.653 kb on + strand, within CCNA_00476 at 493.661 kb on - strand, within CCNA_00476 at 493.734 kb on - strand at 493.790 kb on + strand at 493.790 kb on + strand at 493.842 kb on + strand at 493.858 kb on + strand at 493.858 kb on + strand at 493.858 kb on + strand at 493.858 kb on + strand at 493.866 kb on - strand at 493.866 kb on - strand at 493.866 kb on - strand at 493.903 kb on + strand at 493.937 kb on + strand at 493.937 kb on + strand at 493.937 kb on + strand at 493.951 kb on + strand at 493.951 kb on + strand at 493.951 kb on + strand at 493.959 kb on - strand at 493.959 kb on - strand at 493.959 kb on - strand at 493.959 kb on - strand at 493.959 kb on - strand at 493.960 kb on + strand at 493.961 kb on - strand at 493.968 kb on - strand at 493.968 kb on - strand at 493.988 kb on + strand at 493.995 kb on + strand at 493.995 kb on + strand at 493.995 kb on + strand at 493.995 kb on + strand at 494.003 kb on - strand at 494.003 kb on - strand at 494.003 kb on - strand at 494.008 kb on - strand at 494.038 kb on + strand at 494.052 kb on + strand at 494.131 kb on - strand, within CCNA_00477 at 494.131 kb on - strand, within CCNA_00477 at 494.135 kb on + strand, within CCNA_00477 at 494.136 kb on - strand, within CCNA_00477 at 494.143 kb on - strand, within CCNA_00477 at 494.151 kb on - strand, within CCNA_00477 at 494.181 kb on + strand, within CCNA_00477 at 494.181 kb on + strand, within CCNA_00477 at 494.181 kb on + strand, within CCNA_00477 at 494.183 kb on + strand, within CCNA_00477 at 494.189 kb on - strand, within CCNA_00477 at 494.189 kb on - strand, within CCNA_00477 at 494.189 kb on - strand, within CCNA_00477 at 494.189 kb on - strand, within CCNA_00477 at 494.193 kb on + strand, within CCNA_00477 at 494.198 kb on + strand, within CCNA_00477 at 494.201 kb on - strand, within CCNA_00477 at 494.217 kb on + strand, within CCNA_00477 at 494.222 kb on + strand, within CCNA_00477 at 494.223 kb on + strand, within CCNA_00477 at 494.231 kb on - strand, within CCNA_00477 at 494.231 kb on - strand, within CCNA_00477 at 494.233 kb on + strand, within CCNA_00477 at 494.243 kb on + strand, within CCNA_00477 at 494.243 kb on + strand, within CCNA_00477 at 494.251 kb on - strand, within CCNA_00477 at 494.266 kb on - strand at 494.275 kb on - strand at 494.292 kb on + strand at 494.292 kb on + strand at 494.300 kb on - strand at 494.313 kb on + strand at 494.313 kb on + strand at 494.313 kb on + strand at 494.313 kb on + strand at 494.313 kb on + strand at 494.321 kb on - strand at 494.321 kb on - strand at 494.348 kb on + strand at 494.370 kb on + strand at 494.373 kb on - strand at 494.378 kb on - strand at 494.384 kb on + strand at 494.403 kb on + strand at 494.411 kb on - strand at 494.411 kb on - strand at 494.428 kb on + strand at 494.428 kb on + strand at 494.428 kb on + strand at 494.428 kb on + strand at 494.428 kb on + strand at 494.436 kb on - strand at 494.448 kb on + strand at 494.453 kb on - strand at 494.464 kb on - strand at 494.491 kb on - strand, within CCNA_00478 at 494.506 kb on - strand, within CCNA_00478 at 494.540 kb on + strand, within CCNA_00478 at 494.572 kb on + strand, within CCNA_00478 at 494.593 kb on + strand, within CCNA_00478 at 494.594 kb on + strand, within CCNA_00478 at 494.602 kb on - strand, within CCNA_00478 at 494.605 kb on + strand, within CCNA_00478 at 494.616 kb on + strand, within CCNA_00478 at 494.616 kb on + strand, within CCNA_00478 at 494.616 kb on + strand, within CCNA_00478 at 494.624 kb on - strand, within CCNA_00478 at 494.624 kb on - strand, within CCNA_00478 at 494.624 kb on - strand, within CCNA_00478 at 494.639 kb on - strand, within CCNA_00478 at 494.646 kb on - strand, within CCNA_00478 at 494.674 kb on - strand, within CCNA_00478 at 494.676 kb on + strand, within CCNA_00478 at 494.676 kb on + strand, within CCNA_00478 at 494.685 kb on - strand, within CCNA_00478 at 494.703 kb on - strand, within CCNA_00478 at 494.759 kb on + strand, within CCNA_00478 at 494.800 kb on - strand, within CCNA_00478 at 494.807 kb on + strand, within CCNA_00478 at 494.851 kb on + strand, within CCNA_00478 at 494.859 kb on - strand, within CCNA_00478 at 494.861 kb on - strand, within CCNA_00478 at 494.862 kb on + strand, within CCNA_00478 at 494.862 kb on + strand, within CCNA_00478 at 494.870 kb on - strand, within CCNA_00478 at 494.875 kb on + strand, within CCNA_00478 at 494.875 kb on + strand, within CCNA_00478 at 494.883 kb on - strand, within CCNA_00478 at 494.911 kb on + strand, within CCNA_00478 at 494.930 kb on - strand, within CCNA_00478 at 494.982 kb on + strand, within CCNA_00478 at 495.056 kb on + strand, within CCNA_00478 at 495.063 kb on - strand, within CCNA_00478 at 495.069 kb on - strand, within CCNA_00478 at 495.161 kb on - strand at 495.245 kb on + strand at 495.292 kb on + strand at 495.292 kb on + strand at 495.300 kb on - strand at 495.300 kb on - strand at 495.307 kb on + strand at 495.307 kb on + strand at 495.307 kb on + strand at 495.307 kb on + strand at 495.310 kb on - strand at 495.315 kb on - strand at 495.315 kb on - strand at 495.315 kb on - strand at 495.315 kb on - strand at 495.316 kb on + strand at 495.329 kb on - strand at 495.405 kb on + strand, within CCNA_00479 at 495.420 kb on + strand, within CCNA_00479 at 495.420 kb on + strand, within CCNA_00479 at 495.428 kb on - strand, within CCNA_00479 at 495.430 kb on + strand, within CCNA_00479 at 495.438 kb on - strand, within CCNA_00479 at 495.472 kb on + strand, within CCNA_00479 at 495.493 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.503 kb on + strand, within CCNA_00479 at 495.508 kb on + strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.511 kb on - strand, within CCNA_00479 at 495.515 kb on + strand, within CCNA_00479 at 495.518 kb on - strand, within CCNA_00479 at 495.523 kb on - strand, within CCNA_00479 at 495.539 kb on + strand, within CCNA_00479 at 495.545 kb on + strand, within CCNA_00479 at 495.546 kb on + strand, within CCNA_00479 at 495.553 kb on - strand, within CCNA_00479 at 495.553 kb on - strand, within CCNA_00479 at 495.561 kb on + strand, within CCNA_00479 at 495.569 kb on - strand, within CCNA_00479 at 495.601 kb on - strand, within CCNA_00479 at 495.602 kb on - strand, within CCNA_00479 at 495.611 kb on - strand, within CCNA_00479 at 495.615 kb on + strand, within CCNA_00479 at 495.617 kb on - strand, within CCNA_00479 at 495.617 kb on - strand, within CCNA_00479 at 495.620 kb on + strand, within CCNA_00479 at 495.628 kb on + strand at 495.650 kb on + strand at 495.683 kb on + strand at 495.691 kb on - strand at 495.833 kb on + strand at 495.852 kb on - strand at 495.862 kb on - strand, within CCNA_00480 at 495.863 kb on + strand, within CCNA_00480 at 495.871 kb on - strand, within CCNA_00480 at 495.916 kb on - strand, within CCNA_00480 at 495.918 kb on + strand, within CCNA_00480 at 495.925 kb on + strand, within CCNA_00480 at 495.927 kb on - strand, within CCNA_00480 at 495.941 kb on - strand, within CCNA_00480 at 495.941 kb on - strand, within CCNA_00480 at 495.958 kb on + strand, within CCNA_00480 at 495.959 kb on + strand, within CCNA_00480 at 495.959 kb on + strand, within CCNA_00480 at 495.959 kb on + strand, within CCNA_00480 at 495.967 kb on - strand, within CCNA_00480 at 495.967 kb on - strand, within CCNA_00480 at 495.967 kb on - strand, within CCNA_00480 at 495.974 kb on + strand, within CCNA_00480 at 496.041 kb on - strand, within CCNA_00480 at 496.052 kb on + strand, within CCNA_00480 at 496.059 kb on - strand, within CCNA_00480 at 496.065 kb on - strand, within CCNA_00480 at 496.067 kb on - strand, within CCNA_00480 at 496.081 kb on + strand, within CCNA_00480 at 496.084 kb on + strand, within CCNA_00480
Per-strain Table
Position Strand Gene LocusTag Fraction PYE with CHIR-090 10 ug/mL remove 493,429 + CCNA_00476 0.27 -0.7 493,429 + CCNA_00476 0.27 -0.5 493,446 + CCNA_00476 0.31 -0.3 493,446 + CCNA_00476 0.31 -0.3 493,446 + CCNA_00476 0.31 -0.0 493,446 + CCNA_00476 0.31 -0.4 493,454 - CCNA_00476 0.33 -0.6 493,462 + CCNA_00476 0.35 +1.7 493,512 - CCNA_00476 0.48 +0.1 493,520 + CCNA_00476 0.51 -1.6 493,528 - CCNA_00476 0.53 -1.4 493,653 + CCNA_00476 0.85 +0.5 493,661 - CCNA_00476 0.87 -1.2 493,734 - -0.1 493,790 + +0.1 493,790 + -0.3 493,842 + -1.3 493,858 + +1.9 493,858 + -0.7 493,858 + +0.6 493,858 + -0.7 493,866 - -0.8 493,866 - +0.2 493,866 - +0.5 493,903 + -0.3 493,937 + +0.4 493,937 + -0.8 493,937 + -0.1 493,951 + -1.1 493,951 + +0.4 493,951 + +0.1 493,959 - -0.6 493,959 - -0.5 493,959 - -1.6 493,959 - +0.1 493,959 - +0.6 493,960 + -1.5 493,961 - +0.1 493,968 - -0.5 493,968 - +0.7 493,988 + -0.6 493,995 + +0.9 493,995 + -0.0 493,995 + +0.5 493,995 + -0.5 494,003 - -1.8 494,003 - +0.2 494,003 - -0.1 494,008 - +0.4 494,038 + -0.3 494,052 + -2.4 494,131 - CCNA_00477 0.21 -0.0 494,131 - CCNA_00477 0.21 -0.2 494,135 + CCNA_00477 0.23 -1.0 494,136 - CCNA_00477 0.24 -0.3 494,143 - CCNA_00477 0.27 -0.0 494,151 - CCNA_00477 0.31 +0.3 494,181 + CCNA_00477 0.47 +0.6 494,181 + CCNA_00477 0.47 -0.5 494,181 + CCNA_00477 0.47 +1.0 494,183 + CCNA_00477 0.48 -0.4 494,189 - CCNA_00477 0.51 +0.3 494,189 - CCNA_00477 0.51 +0.2 494,189 - CCNA_00477 0.51 -0.0 494,189 - CCNA_00477 0.51 -0.3 494,193 + CCNA_00477 0.53 -1.4 494,198 + CCNA_00477 0.55 +0.4 494,201 - CCNA_00477 0.57 -0.0 494,217 + CCNA_00477 0.65 -0.4 494,222 + CCNA_00477 0.68 +0.5 494,223 + CCNA_00477 0.68 -1.0 494,231 - CCNA_00477 0.72 +1.5 494,231 - CCNA_00477 0.72 +0.5 494,233 + CCNA_00477 0.73 +0.5 494,243 + CCNA_00477 0.78 -0.7 494,243 + CCNA_00477 0.78 -0.8 494,251 - CCNA_00477 0.83 +0.2 494,266 - +1.5 494,275 - -0.5 494,292 + -0.1 494,292 + -1.1 494,300 - +0.5 494,313 + +0.1 494,313 + +0.5 494,313 + +0.6 494,313 + -0.2 494,313 + -0.3 494,321 - -0.7 494,321 - -0.6 494,348 + +0.7 494,370 + -1.8 494,373 - +0.1 494,378 - +0.5 494,384 + +0.1 494,403 + -0.2 494,411 - -0.8 494,411 - +0.8 494,428 + +0.1 494,428 + -2.3 494,428 + -0.9 494,428 + -0.2 494,428 + -0.3 494,436 - -0.7 494,448 + +0.2 494,453 - -0.7 494,464 - -0.5 494,491 - CCNA_00478 0.12 -0.4 494,506 - CCNA_00478 0.14 +0.0 494,540 + CCNA_00478 0.18 -0.9 494,572 + CCNA_00478 0.22 -1.3 494,593 + CCNA_00478 0.25 -0.5 494,594 + CCNA_00478 0.25 +2.8 494,602 - CCNA_00478 0.27 -0.6 494,605 + CCNA_00478 0.27 -0.6 494,616 + CCNA_00478 0.28 -0.5 494,616 + CCNA_00478 0.28 -1.9 494,616 + CCNA_00478 0.28 -1.7 494,624 - CCNA_00478 0.30 +0.2 494,624 - CCNA_00478 0.30 -1.4 494,624 - CCNA_00478 0.30 +0.3 494,639 - CCNA_00478 0.32 -1.8 494,646 - CCNA_00478 0.33 -0.9 494,674 - CCNA_00478 0.36 -3.1 494,676 + CCNA_00478 0.37 -1.4 494,676 + CCNA_00478 0.37 -0.6 494,685 - CCNA_00478 0.38 +0.4 494,703 - CCNA_00478 0.40 -0.4 494,759 + CCNA_00478 0.48 +0.2 494,800 - CCNA_00478 0.53 -0.0 494,807 + CCNA_00478 0.54 -0.5 494,851 + CCNA_00478 0.60 -0.7 494,859 - CCNA_00478 0.61 -1.9 494,861 - CCNA_00478 0.62 -2.2 494,862 + CCNA_00478 0.62 +1.3 494,862 + CCNA_00478 0.62 -2.3 494,870 - CCNA_00478 0.63 -0.1 494,875 + CCNA_00478 0.64 -2.0 494,875 + CCNA_00478 0.64 -0.4 494,883 - CCNA_00478 0.65 +0.2 494,911 + CCNA_00478 0.68 -1.3 494,930 - CCNA_00478 0.71 -0.8 494,982 + CCNA_00478 0.78 -1.0 495,056 + CCNA_00478 0.88 -0.8 495,063 - CCNA_00478 0.89 -2.0 495,069 - CCNA_00478 0.90 -0.9 495,161 - -0.1 495,245 + -1.9 495,292 + -0.7 495,292 + +0.5 495,300 - +0.6 495,300 - -1.5 495,307 + -0.7 495,307 + +0.8 495,307 + +0.3 495,307 + -1.0 495,310 - +0.6 495,315 - -0.6 495,315 - -0.9 495,315 - -0.4 495,315 - -0.9 495,316 + +0.2 495,329 - -0.5 495,405 + CCNA_00479 0.23 -1.0 495,420 + CCNA_00479 0.27 +0.2 495,420 + CCNA_00479 0.27 +0.2 495,428 - CCNA_00479 0.30 +2.3 495,430 + CCNA_00479 0.30 +0.2 495,438 - CCNA_00479 0.33 -0.2 495,472 + CCNA_00479 0.43 -0.2 495,493 + CCNA_00479 0.50 -0.3 495,503 + CCNA_00479 0.53 +0.0 495,503 + CCNA_00479 0.53 -0.6 495,503 + CCNA_00479 0.53 -0.4 495,503 + CCNA_00479 0.53 -0.9 495,503 + CCNA_00479 0.53 -0.0 495,503 + CCNA_00479 0.53 -1.8 495,508 + CCNA_00479 0.54 -0.8 495,511 - CCNA_00479 0.55 +0.1 495,511 - CCNA_00479 0.55 -0.2 495,511 - CCNA_00479 0.55 -2.5 495,511 - CCNA_00479 0.55 -0.3 495,511 - CCNA_00479 0.55 -0.8 495,511 - CCNA_00479 0.55 -0.3 495,511 - CCNA_00479 0.55 -0.4 495,511 - CCNA_00479 0.55 +0.7 495,511 - CCNA_00479 0.55 -1.3 495,511 - CCNA_00479 0.55 -0.1 495,515 + CCNA_00479 0.56 -0.7 495,518 - CCNA_00479 0.57 +0.1 495,523 - CCNA_00479 0.59 -0.9 495,539 + CCNA_00479 0.64 +0.5 495,545 + CCNA_00479 0.66 +0.4 495,546 + CCNA_00479 0.66 +0.9 495,553 - CCNA_00479 0.68 -0.2 495,553 - CCNA_00479 0.68 +0.6 495,561 + CCNA_00479 0.71 -0.7 495,569 - CCNA_00479 0.73 -2.3 495,601 - CCNA_00479 0.83 -0.2 495,602 - CCNA_00479 0.83 -1.6 495,611 - CCNA_00479 0.86 -0.0 495,615 + CCNA_00479 0.87 -2.6 495,617 - CCNA_00479 0.88 -0.6 495,617 - CCNA_00479 0.88 +1.1 495,620 + CCNA_00479 0.89 +0.2 495,628 + +0.1 495,650 + +1.5 495,683 + +0.2 495,691 - -0.3 495,833 + -0.0 495,852 - -0.7 495,862 - CCNA_00480 0.11 -0.7 495,863 + CCNA_00480 0.11 -0.0 495,871 - CCNA_00480 0.11 -0.1 495,916 - CCNA_00480 0.15 -1.0 495,918 + CCNA_00480 0.15 +0.5 495,925 + CCNA_00480 0.15 -0.6 495,927 - CCNA_00480 0.16 +1.5 495,941 - CCNA_00480 0.17 +0.8 495,941 - CCNA_00480 0.17 +0.3 495,958 + CCNA_00480 0.18 -1.5 495,959 + CCNA_00480 0.18 +0.2 495,959 + CCNA_00480 0.18 -0.7 495,959 + CCNA_00480 0.18 -1.1 495,967 - CCNA_00480 0.19 -0.4 495,967 - CCNA_00480 0.19 -1.1 495,967 - CCNA_00480 0.19 +0.2 495,974 + CCNA_00480 0.19 +1.2 496,041 - CCNA_00480 0.24 +1.5 496,052 + CCNA_00480 0.25 +0.1 496,059 - CCNA_00480 0.26 -0.6 496,065 - CCNA_00480 0.26 -1.1 496,067 - CCNA_00480 0.26 -0.8 496,081 + CCNA_00480 0.27 +0.8 496,084 + CCNA_00480 0.28 +0.1
Or see this region's nucleotide sequence