Experiment: L-Tryptophan (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2050 and PfGW456L13_2051 are separated by 113 nucleotides PfGW456L13_2051 and PfGW456L13_2052 overlap by 4 nucleotides PfGW456L13_2052 and PfGW456L13_2053 are separated by 50 nucleotides PfGW456L13_2053 and PfGW456L13_2054 are separated by 8 nucleotides
PfGW456L13_2050 - FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein, at 2,253,871 to 2,254,314
_2050
PfGW456L13_2051 - FIG00955363: hypothetical protein, at 2,254,428 to 2,255,234
_2051
PfGW456L13_2052 - hydrolase, alpha/beta fold family, at 2,255,231 to 2,256,085
_2052
PfGW456L13_2053 - Glutathione S-transferase (EC 2.5.1.18), at 2,256,136 to 2,256,795
_2053
PfGW456L13_2054 - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit, at 2,256,804 to 2,257,610
_2054
Position (kb)
2255
2256
2257 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 2254.325 kb on + strand at 2254.325 kb on + strand at 2254.325 kb on + strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.360 kb on - strand at 2254.374 kb on - strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.576 kb on - strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.854 kb on + strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.983 kb on + strand, within PfGW456L13_2051 at 2254.983 kb on + strand, within PfGW456L13_2051 at 2254.984 kb on - strand, within PfGW456L13_2051 at 2254.984 kb on - strand, within PfGW456L13_2051 at 2254.994 kb on - strand, within PfGW456L13_2051 at 2255.047 kb on + strand, within PfGW456L13_2051 at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.178 kb on - strand at 2255.178 kb on - strand at 2255.196 kb on + strand at 2255.196 kb on + strand at 2255.196 kb on + strand at 2255.197 kb on - strand at 2255.380 kb on + strand, within PfGW456L13_2052 at 2255.381 kb on - strand, within PfGW456L13_2052 at 2255.468 kb on + strand, within PfGW456L13_2052 at 2255.468 kb on + strand, within PfGW456L13_2052 at 2255.469 kb on - strand, within PfGW456L13_2052 at 2255.469 kb on - strand, within PfGW456L13_2052 at 2255.469 kb on - strand, within PfGW456L13_2052 at 2255.469 kb on - strand, within PfGW456L13_2052 at 2255.469 kb on - strand, within PfGW456L13_2052 at 2255.624 kb on - strand, within PfGW456L13_2052 at 2255.624 kb on - strand, within PfGW456L13_2052 at 2255.819 kb on + strand, within PfGW456L13_2052 at 2255.977 kb on - strand, within PfGW456L13_2052 at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.140 kb on + strand at 2256.141 kb on - strand at 2256.141 kb on - strand at 2256.141 kb on - strand at 2256.141 kb on - strand at 2256.141 kb on - strand at 2256.141 kb on - strand at 2256.148 kb on + strand at 2256.149 kb on - strand at 2256.149 kb on - strand at 2256.211 kb on + strand, within PfGW456L13_2053 at 2256.212 kb on - strand, within PfGW456L13_2053 at 2256.355 kb on + strand, within PfGW456L13_2053 at 2256.355 kb on + strand, within PfGW456L13_2053 at 2256.356 kb on - strand, within PfGW456L13_2053 at 2256.356 kb on - strand, within PfGW456L13_2053 at 2256.414 kb on - strand, within PfGW456L13_2053 at 2256.484 kb on + strand, within PfGW456L13_2053 at 2256.759 kb on + strand at 2256.760 kb on - strand at 2256.763 kb on - strand at 2256.763 kb on - strand at 2256.799 kb on + strand at 2256.799 kb on + strand at 2256.850 kb on + strand at 2256.954 kb on + strand, within PfGW456L13_2054 at 2256.955 kb on - strand, within PfGW456L13_2054 at 2256.955 kb on - strand, within PfGW456L13_2054 at 2257.041 kb on + strand, within PfGW456L13_2054 at 2257.042 kb on - strand, within PfGW456L13_2054 at 2257.049 kb on - strand, within PfGW456L13_2054
Per-strain Table
Position Strand Gene LocusTag Fraction L-Tryptophan (C) remove 2,254,325 + +0.9 2,254,325 + -0.5 2,254,325 + +1.0 2,254,326 - -0.7 2,254,326 - +0.6 2,254,326 - -1.2 2,254,326 - +0.2 2,254,326 - +0.3 2,254,360 - +0.5 2,254,374 - +0.7 2,254,397 + +0.6 2,254,397 + -0.2 2,254,397 + -0.7 2,254,397 + -0.5 2,254,397 + -0.9 2,254,397 + +0.0 2,254,397 + -1.9 2,254,397 + -0.4 2,254,397 + +0.4 2,254,397 + +0.7 2,254,397 + +0.5 2,254,397 + -0.4 2,254,397 + +0.8 2,254,398 - -0.5 2,254,398 - +0.9 2,254,398 - +1.1 2,254,398 - +0.7 2,254,398 - +1.7 2,254,398 - -1.0 2,254,398 - -2.4 2,254,427 + +1.4 2,254,427 + -0.7 2,254,427 + +0.4 2,254,427 + +1.8 2,254,428 - -2.2 2,254,428 - -1.2 2,254,428 - -0.4 2,254,428 - +0.7 2,254,428 - +0.8 2,254,428 - -0.8 2,254,575 + PfGW456L13_2051 0.18 -0.5 2,254,575 + PfGW456L13_2051 0.18 -1.4 2,254,575 + PfGW456L13_2051 0.18 -1.1 2,254,576 - PfGW456L13_2051 0.18 +1.2 2,254,753 + PfGW456L13_2051 0.40 +0.4 2,254,753 + PfGW456L13_2051 0.40 +1.0 2,254,753 + PfGW456L13_2051 0.40 +0.7 2,254,753 + PfGW456L13_2051 0.40 -0.3 2,254,806 - PfGW456L13_2051 0.47 -1.8 2,254,806 - PfGW456L13_2051 0.47 +0.4 2,254,806 - PfGW456L13_2051 0.47 -0.3 2,254,854 + PfGW456L13_2051 0.53 -0.2 2,254,855 - PfGW456L13_2051 0.53 -1.0 2,254,855 - PfGW456L13_2051 0.53 +0.6 2,254,855 - PfGW456L13_2051 0.53 +1.4 2,254,855 - PfGW456L13_2051 0.53 -3.2 2,254,855 - PfGW456L13_2051 0.53 -0.7 2,254,908 + PfGW456L13_2051 0.59 +0.6 2,254,908 + PfGW456L13_2051 0.59 -0.3 2,254,908 + PfGW456L13_2051 0.59 -0.8 2,254,908 + PfGW456L13_2051 0.59 -0.3 2,254,909 - PfGW456L13_2051 0.60 +1.5 2,254,909 - PfGW456L13_2051 0.60 +0.4 2,254,909 - PfGW456L13_2051 0.60 -0.5 2,254,909 - PfGW456L13_2051 0.60 -0.3 2,254,979 + PfGW456L13_2051 0.68 +0.5 2,254,979 + PfGW456L13_2051 0.68 +0.2 2,254,979 + PfGW456L13_2051 0.68 -1.7 2,254,980 - PfGW456L13_2051 0.68 -0.6 2,254,980 - PfGW456L13_2051 0.68 +0.7 2,254,980 - PfGW456L13_2051 0.68 -3.2 2,254,980 - PfGW456L13_2051 0.68 -1.1 2,254,983 + PfGW456L13_2051 0.69 +0.5 2,254,983 + PfGW456L13_2051 0.69 +1.0 2,254,984 - PfGW456L13_2051 0.69 +1.7 2,254,984 - PfGW456L13_2051 0.69 +0.6 2,254,994 - PfGW456L13_2051 0.70 -0.5 2,255,047 + PfGW456L13_2051 0.77 +0.2 2,255,177 + -0.1 2,255,177 + -0.3 2,255,177 + +1.0 2,255,177 + -0.6 2,255,178 - -0.1 2,255,178 - -2.7 2,255,196 + -0.1 2,255,196 + -0.5 2,255,196 + -0.7 2,255,197 - -0.2 2,255,380 + PfGW456L13_2052 0.17 -3.3 2,255,381 - PfGW456L13_2052 0.18 -1.4 2,255,468 + PfGW456L13_2052 0.28 +1.1 2,255,468 + PfGW456L13_2052 0.28 +0.1 2,255,469 - PfGW456L13_2052 0.28 -1.4 2,255,469 - PfGW456L13_2052 0.28 -0.7 2,255,469 - PfGW456L13_2052 0.28 -0.8 2,255,469 - PfGW456L13_2052 0.28 -0.1 2,255,469 - PfGW456L13_2052 0.28 -0.2 2,255,624 - PfGW456L13_2052 0.46 -1.0 2,255,624 - PfGW456L13_2052 0.46 -0.2 2,255,819 + PfGW456L13_2052 0.69 +0.8 2,255,977 - PfGW456L13_2052 0.87 +0.8 2,256,140 + +1.7 2,256,140 + +1.1 2,256,140 + +1.0 2,256,140 + -0.1 2,256,140 + -0.6 2,256,140 + +0.9 2,256,140 + -0.9 2,256,140 + +0.7 2,256,140 + -1.7 2,256,140 + -0.2 2,256,141 - +1.0 2,256,141 - -3.9 2,256,141 - -0.7 2,256,141 - -0.8 2,256,141 - +0.3 2,256,141 - -2.5 2,256,148 + +1.0 2,256,149 - -0.4 2,256,149 - -0.3 2,256,211 + PfGW456L13_2053 0.11 -1.8 2,256,212 - PfGW456L13_2053 0.12 +0.1 2,256,355 + PfGW456L13_2053 0.33 -2.1 2,256,355 + PfGW456L13_2053 0.33 +0.5 2,256,356 - PfGW456L13_2053 0.33 -0.1 2,256,356 - PfGW456L13_2053 0.33 +0.7 2,256,414 - PfGW456L13_2053 0.42 -0.3 2,256,484 + PfGW456L13_2053 0.53 +1.2 2,256,759 + -3.5 2,256,760 - -2.2 2,256,763 - -0.5 2,256,763 - -1.3 2,256,799 + -0.7 2,256,799 + -0.5 2,256,850 + -2.7 2,256,954 + PfGW456L13_2054 0.19 +0.4 2,256,955 - PfGW456L13_2054 0.19 -0.3 2,256,955 - PfGW456L13_2054 0.19 -1.1 2,257,041 + PfGW456L13_2054 0.29 -1.0 2,257,042 - PfGW456L13_2054 0.29 +0.9 2,257,049 - PfGW456L13_2054 0.30 -3.1
Or see this region's nucleotide sequence