Experiment: PYE with CHIR-090 10 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt CCNA_00851 and CCNA_00852 are separated by 167 nucleotides CCNA_00852 and CCNA_00853 overlap by 4 nucleotides CCNA_00853 and CCNA_00854 are separated by 129 nucleotides
CCNA_00851: CCNA_00851 - periplasmic multidrug efflux lipoprotein precursor, at 926,304 to 927,470
_00851
CCNA_00852: CCNA_00852 - TetR family transcriptional regulator, at 927,638 to 928,252
_00852
CCNA_00853: CCNA_00853 - 3-isopropylmalate dehydrogenase, at 928,249 to 929,016
_00853
CCNA_00854: CCNA_00854 - metallo-beta-lactamase protein, at 929,146 to 930,738
_00854
Position (kb) 927
928
929 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 926.658 kb on + strand, within CCNA_00851 at 926.684 kb on + strand, within CCNA_00851 at 926.685 kb on + strand, within CCNA_00851 at 926.692 kb on - strand, within CCNA_00851 at 926.692 kb on - strand, within CCNA_00851 at 926.732 kb on + strand, within CCNA_00851 at 926.736 kb on + strand, within CCNA_00851 at 926.739 kb on - strand, within CCNA_00851 at 926.742 kb on + strand, within CCNA_00851 at 926.744 kb on - strand, within CCNA_00851 at 926.747 kb on + strand, within CCNA_00851 at 926.789 kb on - strand, within CCNA_00851 at 926.808 kb on + strand, within CCNA_00851 at 926.811 kb on - strand, within CCNA_00851 at 926.817 kb on - strand, within CCNA_00851 at 926.817 kb on - strand, within CCNA_00851 at 926.817 kb on - strand, within CCNA_00851 at 926.821 kb on - strand, within CCNA_00851 at 926.824 kb on + strand, within CCNA_00851 at 926.824 kb on + strand, within CCNA_00851 at 926.824 kb on + strand, within CCNA_00851 at 926.824 kb on + strand, within CCNA_00851 at 926.827 kb on - strand, within CCNA_00851 at 926.832 kb on - strand, within CCNA_00851 at 926.832 kb on - strand, within CCNA_00851 at 926.832 kb on - strand, within CCNA_00851 at 926.838 kb on - strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.841 kb on + strand, within CCNA_00851 at 926.849 kb on - strand, within CCNA_00851 at 926.849 kb on - strand, within CCNA_00851 at 926.853 kb on + strand, within CCNA_00851 at 926.861 kb on - strand, within CCNA_00851 at 926.875 kb on + strand, within CCNA_00851 at 926.904 kb on + strand, within CCNA_00851 at 926.912 kb on - strand, within CCNA_00851 at 926.912 kb on - strand, within CCNA_00851 at 926.965 kb on + strand, within CCNA_00851 at 926.968 kb on - strand, within CCNA_00851 at 926.968 kb on - strand, within CCNA_00851 at 926.978 kb on - strand, within CCNA_00851 at 927.009 kb on + strand, within CCNA_00851 at 927.011 kb on + strand, within CCNA_00851 at 927.014 kb on - strand, within CCNA_00851 at 927.014 kb on - strand, within CCNA_00851 at 927.061 kb on + strand, within CCNA_00851 at 927.067 kb on + strand, within CCNA_00851 at 927.069 kb on - strand, within CCNA_00851 at 927.074 kb on - strand, within CCNA_00851 at 927.081 kb on - strand, within CCNA_00851 at 927.088 kb on + strand, within CCNA_00851 at 927.088 kb on + strand, within CCNA_00851 at 927.088 kb on + strand, within CCNA_00851 at 927.088 kb on + strand, within CCNA_00851 at 927.088 kb on + strand, within CCNA_00851 at 927.096 kb on - strand, within CCNA_00851 at 927.096 kb on - strand, within CCNA_00851 at 927.115 kb on + strand, within CCNA_00851 at 927.115 kb on + strand, within CCNA_00851 at 927.121 kb on + strand, within CCNA_00851 at 927.121 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.147 kb on + strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.155 kb on - strand, within CCNA_00851 at 927.183 kb on + strand, within CCNA_00851 at 927.186 kb on - strand, within CCNA_00851 at 927.263 kb on + strand, within CCNA_00851 at 927.273 kb on - strand, within CCNA_00851 at 927.287 kb on - strand, within CCNA_00851 at 927.299 kb on + strand, within CCNA_00851 at 927.301 kb on + strand, within CCNA_00851 at 927.307 kb on - strand, within CCNA_00851 at 927.309 kb on - strand, within CCNA_00851 at 927.311 kb on + strand, within CCNA_00851 at 927.319 kb on - strand, within CCNA_00851 at 927.367 kb on + strand at 927.368 kb on - strand at 927.368 kb on - strand at 927.368 kb on - strand at 927.369 kb on - strand at 927.369 kb on - strand at 927.369 kb on - strand at 927.374 kb on - strand at 927.410 kb on + strand at 927.410 kb on - strand at 927.410 kb on - strand at 927.411 kb on + strand at 927.416 kb on + strand at 927.419 kb on - strand at 927.423 kb on + strand at 927.508 kb on + strand at 927.576 kb on + strand at 927.576 kb on - strand at 927.601 kb on - strand at 927.657 kb on + strand at 927.709 kb on + strand, within CCNA_00852 at 927.854 kb on + strand, within CCNA_00852 at 927.859 kb on + strand, within CCNA_00852 at 927.965 kb on + strand, within CCNA_00852 at 927.973 kb on - strand, within CCNA_00852 at 928.064 kb on + strand, within CCNA_00852 at 928.093 kb on + strand, within CCNA_00852 at 928.140 kb on - strand, within CCNA_00852 at 928.153 kb on + strand, within CCNA_00852 at 928.155 kb on + strand, within CCNA_00852 at 928.184 kb on - strand, within CCNA_00852 at 928.184 kb on - strand, within CCNA_00852 at 928.186 kb on + strand, within CCNA_00852 at 928.256 kb on + strand at 928.256 kb on + strand at 928.264 kb on - strand at 928.266 kb on + strand at 928.266 kb on + strand at 928.274 kb on - strand at 928.287 kb on - strand at 928.291 kb on + strand at 928.291 kb on + strand at 928.294 kb on - strand at 928.294 kb on - strand at 928.329 kb on + strand, within CCNA_00853 at 928.336 kb on + strand, within CCNA_00853 at 928.337 kb on - strand, within CCNA_00853 at 928.357 kb on + strand, within CCNA_00853 at 928.362 kb on + strand, within CCNA_00853 at 928.365 kb on - strand, within CCNA_00853 at 928.403 kb on + strand, within CCNA_00853 at 928.452 kb on + strand, within CCNA_00853 at 928.460 kb on + strand, within CCNA_00853 at 928.461 kb on - strand, within CCNA_00853 at 928.511 kb on - strand, within CCNA_00853 at 928.519 kb on - strand, within CCNA_00853 at 928.585 kb on + strand, within CCNA_00853 at 928.593 kb on - strand, within CCNA_00853 at 928.598 kb on - strand, within CCNA_00853 at 928.598 kb on - strand, within CCNA_00853 at 928.602 kb on + strand, within CCNA_00853 at 928.609 kb on + strand, within CCNA_00853 at 928.614 kb on + strand, within CCNA_00853 at 928.621 kb on - strand, within CCNA_00853 at 928.622 kb on - strand, within CCNA_00853 at 928.622 kb on - strand, within CCNA_00853 at 928.622 kb on - strand, within CCNA_00853 at 928.622 kb on - strand, within CCNA_00853 at 928.647 kb on + strand, within CCNA_00853 at 928.656 kb on - strand, within CCNA_00853 at 928.678 kb on - strand, within CCNA_00853 at 928.681 kb on + strand, within CCNA_00853 at 928.689 kb on - strand, within CCNA_00853 at 928.720 kb on - strand, within CCNA_00853 at 928.727 kb on - strand, within CCNA_00853 at 928.729 kb on + strand, within CCNA_00853 at 928.770 kb on - strand, within CCNA_00853 at 928.827 kb on + strand, within CCNA_00853 at 928.827 kb on + strand, within CCNA_00853 at 928.873 kb on + strand, within CCNA_00853 at 928.900 kb on + strand, within CCNA_00853 at 928.986 kb on + strand at 928.986 kb on + strand at 928.994 kb on + strand at 928.996 kb on + strand at 929.042 kb on + strand at 929.049 kb on + strand at 929.050 kb on - strand at 929.070 kb on + strand at 929.070 kb on + strand at 929.076 kb on + strand at 929.084 kb on - strand at 929.084 kb on - strand at 929.089 kb on - strand at 929.102 kb on + strand at 929.120 kb on + strand at 929.120 kb on + strand at 929.138 kb on + strand at 929.146 kb on - strand at 929.157 kb on - strand at 929.222 kb on + strand at 929.222 kb on + strand at 929.222 kb on + strand at 929.222 kb on + strand at 929.230 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction PYE with CHIR-090 10 ug/mL remove 926,658 + CCNA_00851 0.30 +0.3 926,684 + CCNA_00851 0.33 -0.1 926,685 + CCNA_00851 0.33 -1.3 926,692 - CCNA_00851 0.33 +0.4 926,692 - CCNA_00851 0.33 -0.4 926,732 + CCNA_00851 0.37 +0.6 926,736 + CCNA_00851 0.37 -1.2 926,739 - CCNA_00851 0.37 +0.9 926,742 + CCNA_00851 0.38 -1.3 926,744 - CCNA_00851 0.38 -2.0 926,747 + CCNA_00851 0.38 -1.5 926,789 - CCNA_00851 0.42 -0.3 926,808 + CCNA_00851 0.43 -0.2 926,811 - CCNA_00851 0.43 +0.8 926,817 - CCNA_00851 0.44 -0.7 926,817 - CCNA_00851 0.44 -0.4 926,817 - CCNA_00851 0.44 -1.0 926,821 - CCNA_00851 0.44 +0.4 926,824 + CCNA_00851 0.45 -1.9 926,824 + CCNA_00851 0.45 -1.8 926,824 + CCNA_00851 0.45 +0.9 926,824 + CCNA_00851 0.45 -0.8 926,827 - CCNA_00851 0.45 +1.1 926,832 - CCNA_00851 0.45 -1.0 926,832 - CCNA_00851 0.45 -0.2 926,832 - CCNA_00851 0.45 -1.3 926,838 - CCNA_00851 0.46 -1.1 926,841 + CCNA_00851 0.46 +0.3 926,841 + CCNA_00851 0.46 -1.3 926,841 + CCNA_00851 0.46 -1.4 926,841 + CCNA_00851 0.46 -0.0 926,841 + CCNA_00851 0.46 -0.9 926,841 + CCNA_00851 0.46 +1.7 926,841 + CCNA_00851 0.46 -1.1 926,841 + CCNA_00851 0.46 -0.2 926,849 - CCNA_00851 0.47 +0.5 926,849 - CCNA_00851 0.47 -0.9 926,853 + CCNA_00851 0.47 -0.7 926,861 - CCNA_00851 0.48 +0.9 926,875 + CCNA_00851 0.49 +0.2 926,904 + CCNA_00851 0.51 -0.6 926,912 - CCNA_00851 0.52 -1.5 926,912 - CCNA_00851 0.52 -0.7 926,965 + CCNA_00851 0.57 -1.2 926,968 - CCNA_00851 0.57 -0.1 926,968 - CCNA_00851 0.57 +0.2 926,978 - CCNA_00851 0.58 +1.1 927,009 + CCNA_00851 0.60 +1.1 927,011 + CCNA_00851 0.61 -0.8 927,014 - CCNA_00851 0.61 -0.2 927,014 - CCNA_00851 0.61 +1.3 927,061 + CCNA_00851 0.65 +0.1 927,067 + CCNA_00851 0.65 -0.3 927,069 - CCNA_00851 0.66 -0.4 927,074 - CCNA_00851 0.66 -0.5 927,081 - CCNA_00851 0.67 -0.6 927,088 + CCNA_00851 0.67 -0.4 927,088 + CCNA_00851 0.67 -0.3 927,088 + CCNA_00851 0.67 +0.0 927,088 + CCNA_00851 0.67 +1.0 927,088 + CCNA_00851 0.67 -0.4 927,096 - CCNA_00851 0.68 -0.8 927,096 - CCNA_00851 0.68 -1.1 927,115 + CCNA_00851 0.69 -0.1 927,115 + CCNA_00851 0.69 +0.6 927,121 + CCNA_00851 0.70 -0.7 927,121 + CCNA_00851 0.70 -0.1 927,147 + CCNA_00851 0.72 +0.3 927,147 + CCNA_00851 0.72 -1.4 927,147 + CCNA_00851 0.72 +0.9 927,147 + CCNA_00851 0.72 -1.5 927,147 + CCNA_00851 0.72 +1.7 927,147 + CCNA_00851 0.72 +1.8 927,147 + CCNA_00851 0.72 +0.5 927,147 + CCNA_00851 0.72 +0.4 927,147 + CCNA_00851 0.72 -0.7 927,147 + CCNA_00851 0.72 +0.0 927,155 - CCNA_00851 0.73 -1.2 927,155 - CCNA_00851 0.73 -0.7 927,155 - CCNA_00851 0.73 -0.7 927,155 - CCNA_00851 0.73 -0.5 927,155 - CCNA_00851 0.73 -0.5 927,155 - CCNA_00851 0.73 -1.0 927,155 - CCNA_00851 0.73 -0.8 927,155 - CCNA_00851 0.73 -0.9 927,183 + CCNA_00851 0.75 -1.0 927,186 - CCNA_00851 0.76 -1.7 927,263 + CCNA_00851 0.82 -0.7 927,273 - CCNA_00851 0.83 -1.3 927,287 - CCNA_00851 0.84 -1.0 927,299 + CCNA_00851 0.85 -2.1 927,301 + CCNA_00851 0.85 -0.8 927,307 - CCNA_00851 0.86 -0.1 927,309 - CCNA_00851 0.86 -0.4 927,311 + CCNA_00851 0.86 -0.1 927,319 - CCNA_00851 0.87 -1.3 927,367 + -1.5 927,368 - -0.6 927,368 - -0.1 927,368 - -0.2 927,369 - -0.4 927,369 - -0.6 927,369 - +3.3 927,374 - -1.1 927,410 + -0.1 927,410 - -0.3 927,410 - +0.9 927,411 + +1.9 927,416 + -0.4 927,419 - +0.5 927,423 + -1.5 927,508 + +1.0 927,576 + -0.3 927,576 - +0.7 927,601 - -0.5 927,657 + +1.3 927,709 + CCNA_00852 0.12 +0.8 927,854 + CCNA_00852 0.35 +1.3 927,859 + CCNA_00852 0.36 +1.1 927,965 + CCNA_00852 0.53 +0.2 927,973 - CCNA_00852 0.54 +1.1 928,064 + CCNA_00852 0.69 +0.9 928,093 + CCNA_00852 0.74 -1.3 928,140 - CCNA_00852 0.82 +1.9 928,153 + CCNA_00852 0.84 +1.6 928,155 + CCNA_00852 0.84 +0.2 928,184 - CCNA_00852 0.89 -0.5 928,184 - CCNA_00852 0.89 +0.3 928,186 + CCNA_00852 0.89 -0.4 928,256 + +0.3 928,256 + +0.3 928,264 - -0.3 928,266 + -0.4 928,266 + +0.2 928,274 - +0.5 928,287 - +0.1 928,291 + -1.0 928,291 + +0.6 928,294 - -0.4 928,294 - -0.9 928,329 + CCNA_00853 0.10 +0.3 928,336 + CCNA_00853 0.11 -0.0 928,337 - CCNA_00853 0.11 +0.4 928,357 + CCNA_00853 0.14 -2.4 928,362 + CCNA_00853 0.15 +0.6 928,365 - CCNA_00853 0.15 +0.8 928,403 + CCNA_00853 0.20 -1.2 928,452 + CCNA_00853 0.26 +0.1 928,460 + CCNA_00853 0.27 -0.9 928,461 - CCNA_00853 0.28 +0.5 928,511 - CCNA_00853 0.34 -0.2 928,519 - CCNA_00853 0.35 -0.3 928,585 + CCNA_00853 0.44 -0.4 928,593 - CCNA_00853 0.45 +0.2 928,598 - CCNA_00853 0.45 -0.1 928,598 - CCNA_00853 0.45 -0.5 928,602 + CCNA_00853 0.46 -0.8 928,609 + CCNA_00853 0.47 -0.3 928,614 + CCNA_00853 0.48 -1.5 928,621 - CCNA_00853 0.48 -0.6 928,622 - CCNA_00853 0.49 -0.5 928,622 - CCNA_00853 0.49 +1.3 928,622 - CCNA_00853 0.49 -1.6 928,622 - CCNA_00853 0.49 -1.3 928,647 + CCNA_00853 0.52 +2.1 928,656 - CCNA_00853 0.53 -0.5 928,678 - CCNA_00853 0.56 -2.0 928,681 + CCNA_00853 0.56 +0.6 928,689 - CCNA_00853 0.57 -1.7 928,720 - CCNA_00853 0.61 -1.4 928,727 - CCNA_00853 0.62 -1.0 928,729 + CCNA_00853 0.62 -0.9 928,770 - CCNA_00853 0.68 -2.0 928,827 + CCNA_00853 0.75 -0.6 928,827 + CCNA_00853 0.75 +0.6 928,873 + CCNA_00853 0.81 -0.2 928,900 + CCNA_00853 0.85 -0.1 928,986 + +1.3 928,986 + +0.3 928,994 + +0.4 928,996 + -0.8 929,042 + +0.8 929,049 + -0.3 929,050 - +0.7 929,070 + -0.9 929,070 + -0.1 929,076 + -0.5 929,084 - -0.4 929,084 - -2.0 929,089 - +0.3 929,102 + +0.8 929,120 + +0.3 929,120 + +0.1 929,138 + -1.5 929,146 - -0.2 929,157 - +0.0 929,222 + -1.2 929,222 + +1.1 929,222 + +0.3 929,222 + +0.1 929,230 - -0.7
Or see this region's nucleotide sequence