Experiment: L-Histidine (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_326 and PfGW456L13_327 are separated by 57 nucleotides PfGW456L13_327 and PfGW456L13_328 are separated by 319 nucleotides PfGW456L13_328 and PfGW456L13_329 overlap by 4 nucleotides
PfGW456L13_326 - Urocanate hydratase (EC 4.2.1.49) (from data) , at 381,509 to 383,191
_326
PfGW456L13_327 - hypothetical protein, at 383,249 to 383,368
_327
PfGW456L13_328 - Conserved hypothetical protein (perhaps related to histidine degradation), at 383,688 to 384,257
_328
PfGW456L13_329 - Histidine utilization repressor, at 384,254 to 385,003
_329
Position (kb)
383
384 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1 at 382.500 kb on + strand, within PfGW456L13_326 at 382.500 kb on + strand, within PfGW456L13_326 at 382.500 kb on + strand, within PfGW456L13_326 at 382.500 kb on + strand, within PfGW456L13_326 at 382.501 kb on - strand, within PfGW456L13_326 at 382.501 kb on - strand, within PfGW456L13_326 at 382.501 kb on - strand, within PfGW456L13_326 at 382.501 kb on - strand, within PfGW456L13_326 at 382.501 kb on - strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.704 kb on + strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.705 kb on - strand, within PfGW456L13_326 at 382.737 kb on + strand, within PfGW456L13_326 at 382.737 kb on + strand, within PfGW456L13_326 at 382.737 kb on + strand, within PfGW456L13_326 at 382.738 kb on - strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.770 kb on + strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.771 kb on - strand, within PfGW456L13_326 at 382.800 kb on + strand, within PfGW456L13_326 at 382.800 kb on + strand, within PfGW456L13_326 at 382.800 kb on + strand, within PfGW456L13_326 at 382.800 kb on + strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.801 kb on - strand, within PfGW456L13_326 at 382.992 kb on + strand, within PfGW456L13_326 at 382.993 kb on - strand, within PfGW456L13_326 at 383.005 kb on + strand, within PfGW456L13_326 at 383.031 kb on + strand at 383.031 kb on + strand at 383.031 kb on + strand at 383.032 kb on - strand at 383.048 kb on - strand at 383.173 kb on + strand at 383.173 kb on + strand at 383.174 kb on - strand at 383.174 kb on - strand at 383.174 kb on - strand at 383.174 kb on - strand at 383.179 kb on + strand at 383.179 kb on + strand at 383.180 kb on - strand at 383.306 kb on + strand, within PfGW456L13_327 at 383.306 kb on + strand, within PfGW456L13_327 at 383.307 kb on - strand, within PfGW456L13_327 at 383.312 kb on + strand, within PfGW456L13_327 at 383.313 kb on - strand, within PfGW456L13_327 at 383.320 kb on + strand, within PfGW456L13_327 at 383.321 kb on - strand, within PfGW456L13_327 at 383.326 kb on + strand, within PfGW456L13_327 at 383.326 kb on + strand, within PfGW456L13_327 at 383.330 kb on + strand, within PfGW456L13_327 at 383.331 kb on - strand, within PfGW456L13_327 at 383.472 kb on - strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.651 kb on + strand at 383.673 kb on + strand at 383.673 kb on + strand at 383.674 kb on - strand at 383.674 kb on - strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.687 kb on - strand at 383.687 kb on - strand at 383.687 kb on - strand at 383.831 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.921 kb on - strand, within PfGW456L13_328 at 384.237 kb on + strand at 384.238 kb on - strand at 384.247 kb on - strand at 384.247 kb on - strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.260 kb on - strand at 384.260 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction L-Histidine (C) remove 382,500 + PfGW456L13_326 0.59 -4.2 382,500 + PfGW456L13_326 0.59 -4.2 382,500 + PfGW456L13_326 0.59 -4.0 382,500 + PfGW456L13_326 0.59 -2.6 382,501 - PfGW456L13_326 0.59 -3.2 382,501 - PfGW456L13_326 0.59 -2.9 382,501 - PfGW456L13_326 0.59 -4.3 382,501 - PfGW456L13_326 0.59 -2.9 382,501 - PfGW456L13_326 0.59 -1.6 382,704 + PfGW456L13_326 0.71 -4.4 382,704 + PfGW456L13_326 0.71 -3.8 382,704 + PfGW456L13_326 0.71 -3.3 382,704 + PfGW456L13_326 0.71 -3.6 382,704 + PfGW456L13_326 0.71 -4.3 382,704 + PfGW456L13_326 0.71 -5.2 382,705 - PfGW456L13_326 0.71 -4.0 382,705 - PfGW456L13_326 0.71 -3.3 382,705 - PfGW456L13_326 0.71 -5.1 382,705 - PfGW456L13_326 0.71 -1.9 382,705 - PfGW456L13_326 0.71 -1.9 382,705 - PfGW456L13_326 0.71 -2.5 382,737 + PfGW456L13_326 0.73 -2.6 382,737 + PfGW456L13_326 0.73 -0.0 382,737 + PfGW456L13_326 0.73 -3.5 382,738 - PfGW456L13_326 0.73 -4.1 382,770 + PfGW456L13_326 0.75 -4.6 382,770 + PfGW456L13_326 0.75 -2.7 382,770 + PfGW456L13_326 0.75 -4.1 382,770 + PfGW456L13_326 0.75 -4.1 382,770 + PfGW456L13_326 0.75 -0.8 382,770 + PfGW456L13_326 0.75 -2.7 382,771 - PfGW456L13_326 0.75 -3.4 382,771 - PfGW456L13_326 0.75 -2.5 382,771 - PfGW456L13_326 0.75 -1.8 382,771 - PfGW456L13_326 0.75 -3.3 382,771 - PfGW456L13_326 0.75 -2.3 382,771 - PfGW456L13_326 0.75 -2.8 382,800 + PfGW456L13_326 0.77 -2.3 382,800 + PfGW456L13_326 0.77 -3.6 382,800 + PfGW456L13_326 0.77 -4.4 382,800 + PfGW456L13_326 0.77 -3.9 382,801 - PfGW456L13_326 0.77 -3.6 382,801 - PfGW456L13_326 0.77 -4.2 382,801 - PfGW456L13_326 0.77 -4.0 382,801 - PfGW456L13_326 0.77 -2.6 382,801 - PfGW456L13_326 0.77 -2.3 382,801 - PfGW456L13_326 0.77 -2.9 382,992 + PfGW456L13_326 0.88 -1.6 382,993 - PfGW456L13_326 0.88 -2.6 383,005 + PfGW456L13_326 0.89 -2.8 383,031 + -1.8 383,031 + -2.6 383,031 + -3.6 383,032 - -1.4 383,048 - -3.2 383,173 + -3.9 383,173 + -3.5 383,174 - -1.4 383,174 - -0.8 383,174 - -4.1 383,174 - -3.0 383,179 + -3.6 383,179 + -3.6 383,180 - -1.8 383,306 + PfGW456L13_327 0.47 -2.6 383,306 + PfGW456L13_327 0.47 -3.8 383,307 - PfGW456L13_327 0.48 -3.3 383,312 + PfGW456L13_327 0.53 -4.1 383,313 - PfGW456L13_327 0.53 -4.8 383,320 + PfGW456L13_327 0.59 -2.9 383,321 - PfGW456L13_327 0.60 -4.1 383,326 + PfGW456L13_327 0.64 -3.3 383,326 + PfGW456L13_327 0.64 -3.0 383,330 + PfGW456L13_327 0.68 -3.3 383,331 - PfGW456L13_327 0.68 -4.3 383,472 - -2.4 383,620 + +0.5 383,620 + -1.0 383,620 + -1.3 383,620 + -1.0 383,621 - +0.3 383,621 - -1.2 383,621 - +0.3 383,621 - -0.4 383,621 - +0.2 383,651 + -1.0 383,673 + -1.7 383,673 + +1.0 383,674 - +0.0 383,674 - -0.4 383,686 + +0.9 383,686 + -1.8 383,686 + -0.1 383,686 + -0.1 383,686 + +0.0 383,686 + +0.4 383,686 + -3.8 383,687 - -0.7 383,687 - -1.3 383,687 - -1.5 383,831 + PfGW456L13_328 0.25 -3.6 383,920 + PfGW456L13_328 0.41 -4.2 383,920 + PfGW456L13_328 0.41 -1.8 383,920 + PfGW456L13_328 0.41 -2.1 383,921 - PfGW456L13_328 0.41 -3.5 384,237 + -2.4 384,238 - -2.5 384,247 - -2.3 384,247 - -1.3 384,259 + -1.3 384,259 + -2.7 384,259 + -2.2 384,259 + -2.4 384,260 - -0.9 384,260 - -2.5
Or see this region's nucleotide sequence