Experiment: L-Histidine (C) 
Only strains with sufficient reads to estimate fitness are shown,
                   but the strain fitness values are still rather noisy and may be biased towards zero.
                   Strains near the edge of a gene are not shown as being associated with that
                   gene (they are in grey).
                   Strains in the central 10-90% of a gene are color coded by the insertion's strand.
                   Usually, "+" means that the selectable marker is encoded on the forward strand,
                   i.e., transcribed rightward. 
    
        
         
    
        
         
    
        
         
    
        
         
    
         
     
500 nt PfGW456L13_1452 and PfGW456L13_1453 are separated by 361 nucleotides PfGW456L13_1453 and PfGW456L13_1454 are separated by 60 nucleotides PfGW456L13_1454 and PfGW456L13_1455 are separated by 21 nucleotides 
        PfGW456L13_1452 - Serine hydroxymethyltransferase (EC 2.1.2.1), at 1,602,159 to 1,605,935 
        _1452 
         
        
        PfGW456L13_1453 - Glutathione-regulated potassium-efflux system ATP-binding protein, at 1,606,297 to 1,607,961 
        _1453 
         
        
        PfGW456L13_1454 - hypothetical protein, at 1,608,022 to 1,608,288 
        _1454 
         
        
        PfGW456L13_1455 - NADP-specific glutamate dehydrogenase (EC 1.4.1.4), at 1,608,310 to 1,609,647 
        _1455 
         Position (kb) 1606 
1607 
1608 Strain fitness (log2 ratio) -4 
-3 
-2 
-1 
0 
1 
2 at 1605.488 kb on - strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.522 kb on + strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.523 kb on - strand, within PfGW456L13_1452 at 1605.559 kb on + strand at 1605.560 kb on - strand at 1605.586 kb on - strand at 1605.586 kb on - strand at 1605.601 kb on + strand at 1605.601 kb on + strand at 1605.601 kb on + strand at 1605.601 kb on + strand at 1605.601 kb on + strand at 1605.601 kb on + strand at 1605.602 kb on - strand at 1605.602 kb on - strand at 1605.602 kb on - strand at 1605.602 kb on - strand at 1605.602 kb on - strand at 1605.602 kb on - strand at 1605.823 kb on + strand at 1605.823 kb on + strand at 1605.824 kb on - strand at 1605.824 kb on - strand at 1605.824 kb on - strand at 1605.824 kb on - strand at 1605.835 kb on + strand at 1605.835 kb on + strand at 1605.835 kb on + strand at 1605.835 kb on + strand at 1605.836 kb on - strand at 1605.836 kb on - strand at 1605.836 kb on - strand at 1605.906 kb on + strand at 1605.906 kb on + strand at 1605.907 kb on - strand at 1605.909 kb on + strand at 1605.909 kb on + strand at 1605.909 kb on + strand at 1605.909 kb on + strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1605.910 kb on - strand at 1606.012 kb on + strand at 1606.012 kb on + strand at 1606.012 kb on + strand at 1606.013 kb on - strand at 1606.013 kb on - strand at 1606.013 kb on - strand at 1606.049 kb on + strand at 1606.049 kb on + strand at 1606.049 kb on + strand at 1606.049 kb on + strand at 1606.049 kb on + strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.050 kb on - strand at 1606.051 kb on + strand at 1606.052 kb on - strand at 1606.052 kb on - strand at 1606.140 kb on - strand at 1606.140 kb on - strand at 1606.144 kb on + strand at 1606.144 kb on + strand at 1606.144 kb on + strand at 1606.145 kb on - strand at 1606.145 kb on - strand at 1606.145 kb on - strand at 1606.158 kb on - strand at 1606.179 kb on + strand at 1606.180 kb on - strand at 1606.180 kb on - strand at 1606.180 kb on - strand at 1606.180 kb on - strand at 1606.287 kb on + strand at 1606.287 kb on + strand at 1606.287 kb on + strand at 1606.287 kb on + strand at 1606.287 kb on + strand at 1606.288 kb on - strand at 1606.288 kb on - strand at 1606.306 kb on + strand at 1606.306 kb on + strand at 1606.306 kb on + strand at 1606.306 kb on + strand at 1606.307 kb on - strand at 1606.307 kb on - strand at 1606.307 kb on - strand at 1606.307 kb on - strand at 1606.307 kb on - strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.310 kb on + strand at 1606.311 kb on - strand at 1606.311 kb on - strand at 1606.311 kb on - strand at 1606.311 kb on - strand at 1606.311 kb on - strand at 1606.618 kb on + strand, within PfGW456L13_1453 at 1606.954 kb on + strand, within PfGW456L13_1453 at 1606.954 kb on + strand, within PfGW456L13_1453 at 1606.954 kb on + strand, within PfGW456L13_1453 at 1606.955 kb on - strand, within PfGW456L13_1453 at 1606.955 kb on - strand, within PfGW456L13_1453 at 1607.014 kb on + strand, within PfGW456L13_1453 at 1607.014 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.022 kb on + strand, within PfGW456L13_1453 at 1607.026 kb on + strand, within PfGW456L13_1453 at 1607.027 kb on - strand, within PfGW456L13_1453 at 1607.027 kb on - strand, within PfGW456L13_1453 at 1607.027 kb on - strand, within PfGW456L13_1453 at 1607.027 kb on - strand, within PfGW456L13_1453 at 1607.230 kb on + strand, within PfGW456L13_1453 at 1607.230 kb on + strand, within PfGW456L13_1453 at 1607.230 kb on + strand, within PfGW456L13_1453 at 1607.230 kb on + strand, within PfGW456L13_1453 at 1607.231 kb on - strand, within PfGW456L13_1453 at 1607.231 kb on - strand, within PfGW456L13_1453 at 1607.231 kb on - strand, within PfGW456L13_1453 at 1607.231 kb on - strand, within PfGW456L13_1453 at 1607.293 kb on + strand, within PfGW456L13_1453 at 1607.337 kb on + strand, within PfGW456L13_1453 at 1607.338 kb on - strand, within PfGW456L13_1453 at 1607.338 kb on - strand, within PfGW456L13_1453 at 1607.338 kb on - strand, within PfGW456L13_1453 at 1607.554 kb on + strand, within PfGW456L13_1453 at 1607.554 kb on + strand, within PfGW456L13_1453 at 1607.555 kb on - strand, within PfGW456L13_1453 at 1607.555 kb on - strand, within PfGW456L13_1453 at 1607.555 kb on - strand, within PfGW456L13_1453 at 1607.555 kb on - strand, within PfGW456L13_1453 at 1607.555 kb on - strand, within PfGW456L13_1453 at 1607.571 kb on + strand, within PfGW456L13_1453 at 1607.571 kb on + strand, within PfGW456L13_1453 at 1607.572 kb on - strand, within PfGW456L13_1453 at 1607.572 kb on - strand, within PfGW456L13_1453 at 1607.572 kb on - strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.575 kb on + strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.576 kb on - strand, within PfGW456L13_1453 at 1607.871 kb on + strand at 1607.871 kb on + strand at 1607.871 kb on + strand at 1607.871 kb on + strand at 1607.871 kb on + strand at 1607.872 kb on - strand at 1607.872 kb on - strand at 1607.872 kb on - strand at 1607.872 kb on - strand at 1607.872 kb on - strand at 1607.872 kb on - strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.875 kb on + strand at 1607.876 kb on - strand at 1607.876 kb on - strand at 1607.876 kb on - strand at 1607.884 kb on + strand at 1607.885 kb on - strand at 1607.939 kb on + strand at 1607.939 kb on + strand at 1607.939 kb on + strand at 1607.939 kb on + strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.940 kb on - strand at 1607.978 kb on + strand at 1608.029 kb on + strand at 1608.184 kb on + strand, within PfGW456L13_1454 at 1608.190 kb on - strand, within PfGW456L13_1454 at 1608.259 kb on - strand, within PfGW456L13_1454 at 1608.289 kb on + strand at 1608.402 kb on + strand at 1608.436 kb on + strand at 1608.437 kb on - strand at 1608.437 kb on - strand at 1608.574 kb on + strand, within PfGW456L13_1455 at 1608.574 kb on + strand, within PfGW456L13_1455 at 1608.574 kb on + strand, within PfGW456L13_1455 at 1608.574 kb on + strand, within PfGW456L13_1455 at 1608.714 kb on + strand, within PfGW456L13_1455 at 1608.715 kb on - strand, within PfGW456L13_1455 at 1608.715 kb on - strand, within PfGW456L13_1455 at 1608.794 kb on + strand, within PfGW456L13_1455 at 1608.807 kb on + strand, within PfGW456L13_1455 at 1608.850 kb on + strand, within PfGW456L13_1455 at 1608.850 kb on + strand, within PfGW456L13_1455 at 1608.850 kb on + strand, within PfGW456L13_1455 at 1608.851 kb on - strand, within PfGW456L13_1455 at 1608.952 kb on + strand, within PfGW456L13_1455 at 1608.952 kb on + strand, within PfGW456L13_1455 at 1608.953 kb on - strand, within PfGW456L13_1455 at 1608.953 kb on - strand, within PfGW456L13_1455 at 1608.953 kb on - strand, within PfGW456L13_1455  
 
 
Per-strain Table 
Position  Strand  Gene  LocusTag  Fraction L-Histidine (C) remove 1,605,488 -  PfGW456L13_1452 0.88  +0.5 1,605,522 +  PfGW456L13_1452 0.89  +0.6 1,605,522 +  PfGW456L13_1452 0.89  +0.6 1,605,522 +  PfGW456L13_1452 0.89  -1.5 1,605,522 +  PfGW456L13_1452 0.89  -2.3 1,605,522 +  PfGW456L13_1452 0.89  +0.2 1,605,522 +  PfGW456L13_1452 0.89  -1.8 1,605,523 -  PfGW456L13_1452 0.89  +0.7 1,605,523 -  PfGW456L13_1452 0.89  +1.4 1,605,523 -  PfGW456L13_1452 0.89  +0.2 1,605,523 -  PfGW456L13_1452 0.89  -0.0 1,605,523 -  PfGW456L13_1452 0.89  +0.3 1,605,523 -  PfGW456L13_1452 0.89  +0.0 1,605,523 -  PfGW456L13_1452 0.89  +0.3 1,605,559 +  -0.1 1,605,560 -  -0.1 1,605,586 -  -1.8 1,605,586 -  -0.2 1,605,601 +  -0.1 1,605,601 +  +1.0 1,605,601 +  -0.5 1,605,601 +  -0.4 1,605,601 +  -0.8 1,605,601 +  -0.4 1,605,602 -  +0.8 1,605,602 -  +0.2 1,605,602 -  -0.6 1,605,602 -  +1.0 1,605,602 -  +1.4 1,605,602 -  +0.0 1,605,823 +  +1.5 1,605,823 +  +0.6 1,605,824 -  -1.0 1,605,824 -  -0.1 1,605,824 -  +0.5 1,605,824 -  -0.1 1,605,835 +  +1.0 1,605,835 +  +1.0 1,605,835 +  +1.0 1,605,835 +  +0.4 1,605,836 -  -1.5 1,605,836 -  +0.4 1,605,836 -  -1.8 1,605,906 +  +1.2 1,605,906 +  -0.2 1,605,907 -  +0.4 1,605,909 +  -0.1 1,605,909 +  -0.0 1,605,909 +  +0.1 1,605,909 +  -0.0 1,605,910 -  +0.7 1,605,910 -  -3.7 1,605,910 -  +0.6 1,605,910 -  +1.2 1,605,910 -  +0.8 1,605,910 -  -0.0 1,605,910 -  +0.4 1,606,012 +  -0.0 1,606,012 +  -1.0 1,606,012 +  -1.4 1,606,013 -  -0.5 1,606,013 -  -0.2 1,606,013 -  +0.3 1,606,049 +  -0.3 1,606,049 +  +0.9 1,606,049 +  +1.6 1,606,049 +  -0.4 1,606,049 +  +0.6 1,606,050 -  +0.4 1,606,050 -  +1.6 1,606,050 -  -0.6 1,606,050 -  -0.8 1,606,050 -  -0.7 1,606,050 -  -0.3 1,606,050 -  -0.2 1,606,050 -  +1.2 1,606,051 +  +1.2 1,606,052 -  -0.8 1,606,052 -  -1.2 1,606,140 -  -1.2 1,606,140 -  +0.0 1,606,144 +  +0.5 1,606,144 +  -1.0 1,606,144 +  +1.0 1,606,145 -  -0.7 1,606,145 -  -2.4 1,606,145 -  +0.2 1,606,158 -  -1.3 1,606,179 +  +0.8 1,606,180 -  -0.4 1,606,180 -  -0.5 1,606,180 -  -0.8 1,606,180 -  -0.1 1,606,287 +  -0.2 1,606,287 +  -0.3 1,606,287 +  +0.2 1,606,287 +  +0.9 1,606,287 +  +0.0 1,606,288 -  +0.7 1,606,288 -  -2.2 1,606,306 +  -2.5 1,606,306 +  -1.2 1,606,306 +  +0.6 1,606,306 +  -2.2 1,606,307 -  -2.4 1,606,307 -  -2.3 1,606,307 -  -1.8 1,606,307 -  +0.9 1,606,307 -  -0.5 1,606,310 +  +0.5 1,606,310 +  -1.0 1,606,310 +  -2.3 1,606,310 +  -0.3 1,606,310 +  -1.6 1,606,310 +  -3.9 1,606,310 +  -1.0 1,606,310 +  -0.5 1,606,310 +  -1.0 1,606,311 -  -2.1 1,606,311 -  -1.3 1,606,311 -  -0.2 1,606,311 -  +0.8 1,606,311 -  -2.1 1,606,618 +  PfGW456L13_1453 0.19  +0.3 1,606,954 +  PfGW456L13_1453 0.39  -1.3 1,606,954 +  PfGW456L13_1453 0.39  -0.5 1,606,954 +  PfGW456L13_1453 0.39  -3.1 1,606,955 -  PfGW456L13_1453 0.40  -0.7 1,606,955 -  PfGW456L13_1453 0.40  -0.5 1,607,014 +  PfGW456L13_1453 0.43  -0.4 1,607,014 +  PfGW456L13_1453 0.43  -0.4 1,607,022 +  PfGW456L13_1453 0.44  -2.3 1,607,022 +  PfGW456L13_1453 0.44  -2.1 1,607,022 +  PfGW456L13_1453 0.44  -1.0 1,607,022 +  PfGW456L13_1453 0.44  -0.6 1,607,022 +  PfGW456L13_1453 0.44  -0.2 1,607,022 +  PfGW456L13_1453 0.44  -2.7 1,607,026 +  PfGW456L13_1453 0.44  -0.0 1,607,027 -  PfGW456L13_1453 0.44  -3.0 1,607,027 -  PfGW456L13_1453 0.44  -2.5 1,607,027 -  PfGW456L13_1453 0.44  +0.6 1,607,027 -  PfGW456L13_1453 0.44  -0.2 1,607,230 +  PfGW456L13_1453 0.56  +0.0 1,607,230 +  PfGW456L13_1453 0.56  +0.5 1,607,230 +  PfGW456L13_1453 0.56  -1.7 1,607,230 +  PfGW456L13_1453 0.56  -1.5 1,607,231 -  PfGW456L13_1453 0.56  -2.8 1,607,231 -  PfGW456L13_1453 0.56  -1.1 1,607,231 -  PfGW456L13_1453 0.56  -2.5 1,607,231 -  PfGW456L13_1453 0.56  -3.0 1,607,293 +  PfGW456L13_1453 0.60  -2.0 1,607,337 +  PfGW456L13_1453 0.62  -2.1 1,607,338 -  PfGW456L13_1453 0.63  -1.8 1,607,338 -  PfGW456L13_1453 0.63  -2.2 1,607,338 -  PfGW456L13_1453 0.63  -2.6 1,607,554 +  PfGW456L13_1453 0.75  +0.0 1,607,554 +  PfGW456L13_1453 0.75  -1.6 1,607,555 -  PfGW456L13_1453 0.76  -4.0 1,607,555 -  PfGW456L13_1453 0.76  -0.6 1,607,555 -  PfGW456L13_1453 0.76  -1.5 1,607,555 -  PfGW456L13_1453 0.76  -1.4 1,607,555 -  PfGW456L13_1453 0.76  +0.5 1,607,571 +  PfGW456L13_1453 0.77  -0.8 1,607,571 +  PfGW456L13_1453 0.77  -0.3 1,607,572 -  PfGW456L13_1453 0.77  -1.7 1,607,572 -  PfGW456L13_1453 0.77  -1.4 1,607,572 -  PfGW456L13_1453 0.77  -1.3 1,607,575 +  PfGW456L13_1453 0.77  -0.1 1,607,575 +  PfGW456L13_1453 0.77  -0.3 1,607,575 +  PfGW456L13_1453 0.77  -0.5 1,607,575 +  PfGW456L13_1453 0.77  -1.1 1,607,575 +  PfGW456L13_1453 0.77  -3.0 1,607,575 +  PfGW456L13_1453 0.77  -0.5 1,607,575 +  PfGW456L13_1453 0.77  -1.0 1,607,575 +  PfGW456L13_1453 0.77  -0.8 1,607,575 +  PfGW456L13_1453 0.77  -1.7 1,607,575 +  PfGW456L13_1453 0.77  -1.1 1,607,575 +  PfGW456L13_1453 0.77  -1.9 1,607,575 +  PfGW456L13_1453 0.77  +0.5 1,607,575 +  PfGW456L13_1453 0.77  -0.2 1,607,575 +  PfGW456L13_1453 0.77  -1.4 1,607,575 +  PfGW456L13_1453 0.77  -0.7 1,607,575 +  PfGW456L13_1453 0.77  -2.3 1,607,575 +  PfGW456L13_1453 0.77  -0.8 1,607,576 -  PfGW456L13_1453 0.77  -0.1 1,607,576 -  PfGW456L13_1453 0.77  -0.4 1,607,576 -  PfGW456L13_1453 0.77  +0.0 1,607,576 -  PfGW456L13_1453 0.77  -2.0 1,607,576 -  PfGW456L13_1453 0.77  -1.5 1,607,576 -  PfGW456L13_1453 0.77  -1.0 1,607,871 +  +0.3 1,607,871 +  -0.1 1,607,871 +  -1.0 1,607,871 +  -2.1 1,607,871 +  -3.1 1,607,872 -  -0.5 1,607,872 -  -1.7 1,607,872 -  -3.3 1,607,872 -  -1.4 1,607,872 -  -0.1 1,607,872 -  -0.4 1,607,875 +  -0.7 1,607,875 +  -1.9 1,607,875 +  -0.4 1,607,875 +  -1.5 1,607,875 +  +0.6 1,607,875 +  -0.4 1,607,875 +  -0.5 1,607,876 -  -0.5 1,607,876 -  -0.4 1,607,876 -  -0.5 1,607,884 +  -2.8 1,607,885 -  -0.7 1,607,939 +  -0.1 1,607,939 +  -0.2 1,607,939 +  -3.5 1,607,939 +  +0.0 1,607,940 -  -1.8 1,607,940 -  +0.0 1,607,940 -  -3.8 1,607,940 -  +0.5 1,607,940 -  -2.0 1,607,940 -  +0.0 1,607,940 -  -2.9 1,607,940 -  -0.3 1,607,940 -  -2.9 1,607,978 +  +0.6 1,608,029 +  -0.6 1,608,184 +  PfGW456L13_1454 0.61  -0.4 1,608,190 -  PfGW456L13_1454 0.63  +1.1 1,608,259 -  PfGW456L13_1454 0.89  -1.7 1,608,289 +  +0.3 1,608,402 +  +0.4 1,608,436 +  -0.3 1,608,437 -  -0.5 1,608,437 -  +0.0 1,608,574 +  PfGW456L13_1455 0.20  -0.6 1,608,574 +  PfGW456L13_1455 0.20  -2.2 1,608,574 +  PfGW456L13_1455 0.20  +0.0 1,608,574 +  PfGW456L13_1455 0.20  -1.4 1,608,714 +  PfGW456L13_1455 0.30  +0.9 1,608,715 -  PfGW456L13_1455 0.30  +0.7 1,608,715 -  PfGW456L13_1455 0.30  -0.1 1,608,794 +  PfGW456L13_1455 0.36  -0.3 1,608,807 +  PfGW456L13_1455 0.37  +0.0 1,608,850 +  PfGW456L13_1455 0.40  +0.5 1,608,850 +  PfGW456L13_1455 0.40  -0.4 1,608,850 +  PfGW456L13_1455 0.40  -0.5 1,608,851 -  PfGW456L13_1455 0.40  +0.8 1,608,952 +  PfGW456L13_1455 0.48  -0.2 1,608,952 +  PfGW456L13_1455 0.48  +0.0 1,608,953 -  PfGW456L13_1455 0.48  -1.0 1,608,953 -  PfGW456L13_1455 0.48  +1.3 1,608,953 -  PfGW456L13_1455 0.48  +1.9 
Or see this region's nucleotide sequence