Experiment: Ciprofloxacin Hydrochloride 0.0003 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt emrY and emrK overlap by 1 nucleotides emrK and evgA are separated by 415 nucleotides
b2367: emrY - predicted multidrug efflux system (NCBI), at 2,478,660 to 2,480,198
emrY
b2368: emrK - EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component (NCBI), at 2,480,198 to 2,481,361
emrK
b2369: evgA - DNA-binding response regulator in two-component regulatory system with EvgS (NCBI), at 2,481,777 to 2,482,391
evgA
Position (kb)
2480
2481
2482 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 2479.253 kb on - strand, within emrY at 2479.275 kb on - strand, within emrY at 2479.275 kb on - strand, within emrY at 2479.504 kb on - strand, within emrY at 2479.885 kb on - strand, within emrY at 2479.902 kb on - strand, within emrY at 2480.011 kb on - strand, within emrY at 2480.011 kb on - strand, within emrY at 2480.016 kb on - strand, within emrY at 2480.016 kb on - strand, within emrY at 2480.020 kb on + strand, within emrY at 2480.026 kb on + strand, within emrY at 2480.026 kb on + strand, within emrY at 2480.026 kb on - strand, within emrY at 2480.027 kb on + strand, within emrY at 2480.034 kb on - strand, within emrY at 2480.034 kb on - strand, within emrY at 2480.035 kb on - strand, within emrY at 2480.035 kb on - strand, within emrY at 2480.130 kb on - strand at 2480.136 kb on - strand at 2480.156 kb on - strand at 2480.158 kb on - strand at 2480.163 kb on + strand at 2480.171 kb on - strand at 2480.260 kb on - strand at 2480.260 kb on - strand at 2480.260 kb on - strand at 2480.269 kb on - strand at 2480.269 kb on - strand at 2480.270 kb on - strand at 2480.279 kb on - strand at 2480.290 kb on - strand at 2480.295 kb on - strand at 2480.300 kb on - strand at 2480.301 kb on - strand at 2480.301 kb on - strand at 2480.324 kb on - strand, within emrK at 2480.324 kb on - strand, within emrK at 2480.352 kb on - strand, within emrK at 2480.352 kb on - strand, within emrK at 2480.358 kb on - strand, within emrK at 2480.362 kb on + strand, within emrK at 2480.366 kb on - strand, within emrK at 2480.376 kb on + strand, within emrK at 2480.376 kb on - strand, within emrK at 2480.378 kb on - strand, within emrK at 2480.381 kb on + strand, within emrK at 2480.398 kb on + strand, within emrK at 2480.424 kb on + strand, within emrK at 2480.432 kb on - strand, within emrK at 2480.432 kb on - strand, within emrK at 2480.437 kb on - strand, within emrK at 2480.442 kb on - strand, within emrK at 2480.450 kb on + strand, within emrK at 2480.473 kb on + strand, within emrK at 2480.478 kb on + strand, within emrK at 2480.486 kb on + strand, within emrK at 2480.497 kb on + strand, within emrK at 2480.505 kb on - strand, within emrK at 2480.511 kb on + strand, within emrK at 2480.512 kb on + strand, within emrK at 2480.522 kb on + strand, within emrK at 2480.569 kb on + strand, within emrK at 2480.569 kb on + strand, within emrK at 2480.579 kb on + strand, within emrK at 2480.589 kb on + strand, within emrK at 2480.589 kb on + strand, within emrK at 2480.590 kb on - strand, within emrK at 2480.647 kb on - strand, within emrK at 2480.647 kb on - strand, within emrK at 2480.650 kb on + strand, within emrK at 2480.652 kb on + strand, within emrK at 2480.652 kb on + strand, within emrK at 2480.662 kb on + strand, within emrK at 2480.674 kb on - strand, within emrK at 2480.684 kb on + strand, within emrK at 2480.686 kb on + strand, within emrK at 2480.689 kb on + strand, within emrK at 2480.689 kb on + strand, within emrK at 2480.694 kb on + strand, within emrK at 2480.694 kb on + strand, within emrK at 2480.696 kb on + strand, within emrK at 2480.697 kb on + strand, within emrK at 2480.697 kb on + strand, within emrK at 2480.706 kb on + strand, within emrK at 2480.706 kb on + strand, within emrK at 2480.709 kb on - strand, within emrK at 2480.709 kb on - strand, within emrK at 2480.709 kb on - strand, within emrK at 2480.726 kb on + strand, within emrK at 2480.741 kb on + strand, within emrK at 2480.769 kb on + strand at 2480.769 kb on + strand, within emrK at 2480.782 kb on - strand, within emrK at 2480.787 kb on + strand, within emrK at 2480.801 kb on + strand, within emrK at 2480.801 kb on + strand, within emrK at 2480.843 kb on + strand, within emrK at 2480.843 kb on + strand, within emrK at 2480.843 kb on + strand, within emrK at 2480.843 kb on + strand, within emrK at 2480.889 kb on + strand, within emrK at 2480.897 kb on - strand, within emrK at 2480.990 kb on - strand, within emrK at 2481.080 kb on - strand, within emrK at 2481.434 kb on - strand at 2481.444 kb on - strand at 2481.444 kb on - strand at 2481.450 kb on - strand at 2481.450 kb on - strand at 2481.463 kb on - strand at 2481.472 kb on - strand at 2481.485 kb on - strand at 2481.485 kb on - strand at 2481.515 kb on - strand at 2481.515 kb on - strand at 2481.515 kb on - strand at 2481.517 kb on - strand at 2481.521 kb on - strand at 2481.521 kb on - strand at 2481.647 kb on + strand at 2481.647 kb on + strand at 2481.650 kb on + strand at 2481.650 kb on + strand at 2481.666 kb on + strand at 2481.718 kb on + strand at 2481.718 kb on + strand at 2481.725 kb on + strand at 2481.726 kb on + strand at 2481.728 kb on + strand at 2481.734 kb on + strand at 2481.734 kb on + strand at 2481.742 kb on - strand at 2481.869 kb on + strand, within evgA at 2481.886 kb on + strand, within evgA at 2481.888 kb on + strand, within evgA at 2481.896 kb on + strand, within evgA at 2481.896 kb on + strand, within evgA at 2481.905 kb on + strand, within evgA at 2481.942 kb on + strand, within evgA at 2481.946 kb on + strand, within evgA at 2481.946 kb on + strand, within evgA at 2481.946 kb on + strand, within evgA at 2481.955 kb on + strand, within evgA at 2481.955 kb on + strand, within evgA at 2481.957 kb on + strand, within evgA at 2481.973 kb on + strand, within evgA at 2481.984 kb on + strand, within evgA at 2481.984 kb on + strand, within evgA at 2482.043 kb on + strand, within evgA at 2482.043 kb on + strand, within evgA at 2482.044 kb on + strand, within evgA at 2482.045 kb on + strand, within evgA at 2482.136 kb on + strand, within evgA at 2482.138 kb on + strand, within evgA at 2482.149 kb on + strand, within evgA at 2482.156 kb on - strand, within evgA at 2482.227 kb on + strand, within evgA at 2482.235 kb on + strand, within evgA at 2482.235 kb on + strand, within evgA at 2482.235 kb on + strand, within evgA at 2482.308 kb on + strand, within evgA at 2482.355 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Ciprofloxacin Hydrochloride 0.0003 mM remove 2,479,253 - emrY b2367 0.39 +0.5 2,479,275 - emrY b2367 0.40 +0.5 2,479,275 - emrY b2367 0.40 -1.0 2,479,504 - emrY b2367 0.55 +1.5 2,479,885 - emrY b2367 0.80 +1.5 2,479,902 - emrY b2367 0.81 -1.3 2,480,011 - emrY b2367 0.88 +0.5 2,480,011 - emrY b2367 0.88 -0.0 2,480,016 - emrY b2367 0.88 +1.5 2,480,016 - emrY b2367 0.88 -0.8 2,480,020 + emrY b2367 0.88 +1.5 2,480,026 + emrY b2367 0.89 +1.5 2,480,026 + emrY b2367 0.89 +1.5 2,480,026 - emrY b2367 0.89 -1.0 2,480,027 + emrY b2367 0.89 +1.5 2,480,034 - emrY b2367 0.89 +0.5 2,480,034 - emrY b2367 0.89 -1.3 2,480,035 - emrY b2367 0.89 +1.5 2,480,035 - emrY b2367 0.89 +1.5 2,480,130 - +1.5 2,480,136 - +1.5 2,480,156 - +1.5 2,480,158 - +1.7 2,480,163 + +1.5 2,480,171 - +1.5 2,480,260 - -3.5 2,480,260 - +1.5 2,480,260 - +1.5 2,480,269 - +1.5 2,480,269 - +2.3 2,480,270 - +1.2 2,480,279 - -0.9 2,480,290 - +1.5 2,480,295 - -0.8 2,480,300 - -2.4 2,480,301 - -2.3 2,480,301 - -2.0 2,480,324 - emrK b2368 0.11 +3.1 2,480,324 - emrK b2368 0.11 -0.0 2,480,352 - emrK b2368 0.13 -0.8 2,480,352 - emrK b2368 0.13 -1.5 2,480,358 - emrK b2368 0.14 -1.0 2,480,362 + emrK b2368 0.14 -0.5 2,480,366 - emrK b2368 0.14 -2.6 2,480,376 + emrK b2368 0.15 -0.0 2,480,376 - emrK b2368 0.15 -1.0 2,480,378 - emrK b2368 0.15 -0.5 2,480,381 + emrK b2368 0.16 -0.5 2,480,398 + emrK b2368 0.17 -1.0 2,480,424 + emrK b2368 0.19 -0.0 2,480,432 - emrK b2368 0.20 +2.9 2,480,432 - emrK b2368 0.20 -2.0 2,480,437 - emrK b2368 0.21 +1.5 2,480,442 - emrK b2368 0.21 +0.5 2,480,450 + emrK b2368 0.22 -0.8 2,480,473 + emrK b2368 0.24 -2.3 2,480,478 + emrK b2368 0.24 -1.6 2,480,486 + emrK b2368 0.25 -1.5 2,480,497 + emrK b2368 0.26 -0.0 2,480,505 - emrK b2368 0.26 -0.0 2,480,511 + emrK b2368 0.27 +1.5 2,480,512 + emrK b2368 0.27 -0.8 2,480,522 + emrK b2368 0.28 -1.6 2,480,569 + emrK b2368 0.32 -1.5 2,480,569 + emrK b2368 0.32 -1.3 2,480,579 + emrK b2368 0.33 -1.3 2,480,589 + emrK b2368 0.34 +0.3 2,480,589 + emrK b2368 0.34 +1.9 2,480,590 - emrK b2368 0.34 +0.5 2,480,647 - emrK b2368 0.39 +2.3 2,480,647 - emrK b2368 0.39 -2.0 2,480,650 + emrK b2368 0.39 +0.7 2,480,652 + emrK b2368 0.39 -1.0 2,480,652 + emrK b2368 0.39 +0.7 2,480,662 + emrK b2368 0.40 -2.2 2,480,674 - emrK b2368 0.41 +0.5 2,480,684 + emrK b2368 0.42 +1.4 2,480,686 + emrK b2368 0.42 -1.3 2,480,689 + emrK b2368 0.42 -2.6 2,480,689 + emrK b2368 0.42 +0.7 2,480,694 + emrK b2368 0.43 -0.8 2,480,694 + emrK b2368 0.43 -1.3 2,480,696 + emrK b2368 0.43 -2.6 2,480,697 + emrK b2368 0.43 -1.8 2,480,697 + emrK b2368 0.43 +0.7 2,480,706 + emrK b2368 0.44 +0.3 2,480,706 + emrK b2368 0.44 -1.6 2,480,709 - emrK b2368 0.44 +1.5 2,480,709 - emrK b2368 0.44 +1.5 2,480,709 - emrK b2368 0.44 +1.5 2,480,726 + emrK b2368 0.45 -1.0 2,480,741 + emrK b2368 0.47 -2.4 2,480,769 + +3.1 2,480,769 + emrK b2368 0.49 -1.0 2,480,782 - emrK b2368 0.50 +1.5 2,480,787 + emrK b2368 0.51 -1.0 2,480,801 + emrK b2368 0.52 -1.3 2,480,801 + emrK b2368 0.52 +0.8 2,480,843 + emrK b2368 0.55 -0.0 2,480,843 + emrK b2368 0.55 +0.7 2,480,843 + emrK b2368 0.55 -1.9 2,480,843 + emrK b2368 0.55 -1.3 2,480,889 + emrK b2368 0.59 -0.0 2,480,897 - emrK b2368 0.60 +1.5 2,480,990 - emrK b2368 0.68 +0.5 2,481,080 - emrK b2368 0.76 +1.5 2,481,434 - -1.0 2,481,444 - +0.4 2,481,444 - +1.5 2,481,450 - -0.8 2,481,450 - -0.0 2,481,463 - -2.2 2,481,472 - +2.0 2,481,485 - -1.0 2,481,485 - +0.5 2,481,515 - +0.5 2,481,515 - -1.8 2,481,515 - -1.3 2,481,517 - -0.5 2,481,521 - +1.5 2,481,521 - +1.5 2,481,647 + -0.0 2,481,647 + -1.8 2,481,650 + -0.5 2,481,650 + -0.9 2,481,666 + -1.0 2,481,718 + +1.5 2,481,718 + +0.5 2,481,725 + +1.5 2,481,726 + +1.5 2,481,728 + +1.5 2,481,734 + +1.5 2,481,734 + +1.5 2,481,742 - +1.5 2,481,869 + evgA b2369 0.15 -0.5 2,481,886 + evgA b2369 0.18 -0.5 2,481,888 + evgA b2369 0.18 -0.8 2,481,896 + evgA b2369 0.19 +0.5 2,481,896 + evgA b2369 0.19 -0.0 2,481,905 + evgA b2369 0.21 -0.5 2,481,942 + evgA b2369 0.27 -0.0 2,481,946 + evgA b2369 0.27 -1.0 2,481,946 + evgA b2369 0.27 -1.6 2,481,946 + evgA b2369 0.27 +0.5 2,481,955 + evgA b2369 0.29 -0.0 2,481,955 + evgA b2369 0.29 -1.0 2,481,957 + evgA b2369 0.29 +1.5 2,481,973 + evgA b2369 0.32 -1.3 2,481,984 + evgA b2369 0.34 -0.5 2,481,984 + evgA b2369 0.34 -0.0 2,482,043 + evgA b2369 0.43 +1.5 2,482,043 + evgA b2369 0.43 +0.5 2,482,044 + evgA b2369 0.43 +3.5 2,482,045 + evgA b2369 0.44 +1.8 2,482,136 + evgA b2369 0.58 +1.5 2,482,138 + evgA b2369 0.59 +1.5 2,482,149 + evgA b2369 0.60 +1.5 2,482,156 - evgA b2369 0.62 +1.5 2,482,227 + evgA b2369 0.73 +0.5 2,482,235 + evgA b2369 0.74 +1.5 2,482,235 + evgA b2369 0.74 +1.5 2,482,235 + evgA b2369 0.74 +1.5 2,482,308 + evgA b2369 0.86 +0.5 2,482,355 + +1.5
Or see this region's nucleotide sequence