Strain Fitness in Escherichia coli BW25113 around b0570

Experiment: LB Anaerobic with Norfloxacin 0.00000015625 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntnfrB and cusS are separated by 149 nucleotidescusS and cusR overlap by 11 nucleotidescusR and cusC are separated by 156 nucleotides b0569: nfrB - bacteriophage N4 receptor, inner membrane subunit (NCBI), at 590,164 to 592,401 nfrB b0570: cusS - sensory histidine kinase in two-component regulatory system with CusR, senses copper ions (NCBI), at 592,551 to 593,993 cusS b0571: cusR - DNA-binding response regulator in two-component regulatory system with CusS (NCBI), at 593,983 to 594,666 cusR b0572: cusC - copper/silver efflux system, outer membrane component (NCBI), at 594,823 to 596,196 cusC Position (kb) 592 593 594Strain fitness (log2 ratio) -1 0 1at 591.705 kb on + strand, within nfrBat 591.750 kb on - strand, within nfrBat 591.750 kb on - strand, within nfrBat 591.767 kb on + strand, within nfrBat 591.808 kb on + strand, within nfrBat 591.888 kb on + strand, within nfrBat 592.009 kb on + strand, within nfrBat 592.011 kb on + strand, within nfrBat 592.021 kb on - strand, within nfrBat 592.025 kb on + strand, within nfrBat 592.168 kb on - strand, within nfrBat 592.179 kb on - strandat 592.205 kb on + strandat 592.205 kb on + strandat 592.565 kb on - strandat 592.565 kb on - strandat 592.696 kb on + strand, within cusSat 592.776 kb on + strand, within cusSat 592.776 kb on + strand, within cusSat 592.809 kb on - strand, within cusSat 592.822 kb on + strand, within cusSat 592.828 kb on - strand, within cusSat 592.828 kb on - strand, within cusSat 593.025 kb on - strand, within cusSat 593.031 kb on - strand, within cusSat 593.083 kb on + strand, within cusSat 593.091 kb on + strand, within cusSat 593.091 kb on + strand, within cusSat 593.248 kb on - strand, within cusSat 593.368 kb on + strand, within cusSat 593.496 kb on - strand, within cusSat 593.587 kb on + strand, within cusSat 593.611 kb on - strand, within cusSat 593.646 kb on - strand, within cusSat 593.694 kb on - strand, within cusSat 593.694 kb on - strand, within cusSat 593.704 kb on + strand, within cusSat 593.710 kb on - strand, within cusSat 593.887 kb on + strandat 594.000 kb on + strandat 594.000 kb on + strandat 594.001 kb on + strandat 594.001 kb on - strandat 594.149 kb on - strand, within cusRat 594.149 kb on - strand, within cusRat 594.200 kb on - strand, within cusRat 594.200 kb on - strand, within cusRat 594.209 kb on - strand, within cusRat 594.209 kb on - strand, within cusRat 594.219 kb on - strand, within cusRat 594.219 kb on - strand, within cusRat 594.343 kb on - strand, within cusRat 594.460 kb on - strand, within cusRat 594.460 kb on - strand, within cusRat 594.474 kb on - strand, within cusRat 594.515 kb on - strand, within cusRat 594.557 kb on + strand, within cusRat 594.557 kb on + strand, within cusRat 594.723 kb on - strandat 594.743 kb on - strandat 594.895 kb on - strandat 594.952 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction LB Anaerobic with Norfloxacin 0.00000015625 mM
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591,705 + nfrB b0569 0.69 +0.0
591,750 - nfrB b0569 0.71 -0.2
591,750 - nfrB b0569 0.71 -0.7
591,767 + nfrB b0569 0.72 -0.1
591,808 + nfrB b0569 0.73 +0.4
591,888 + nfrB b0569 0.77 -0.4
592,009 + nfrB b0569 0.82 -0.3
592,011 + nfrB b0569 0.83 -0.2
592,021 - nfrB b0569 0.83 +0.1
592,025 + nfrB b0569 0.83 +0.6
592,168 - nfrB b0569 0.90 +0.1
592,179 - -0.5
592,205 + -1.1
592,205 + -0.5
592,565 - +0.6
592,565 - +0.6
592,696 + cusS b0570 0.10 +0.0
592,776 + cusS b0570 0.16 -0.3
592,776 + cusS b0570 0.16 -0.0
592,809 - cusS b0570 0.18 +1.5
592,822 + cusS b0570 0.19 +0.3
592,828 - cusS b0570 0.19 +0.7
592,828 - cusS b0570 0.19 +0.3
593,025 - cusS b0570 0.33 -0.4
593,031 - cusS b0570 0.33 +1.1
593,083 + cusS b0570 0.37 +0.6
593,091 + cusS b0570 0.37 +1.0
593,091 + cusS b0570 0.37 +0.7
593,248 - cusS b0570 0.48 +0.0
593,368 + cusS b0570 0.57 +0.7
593,496 - cusS b0570 0.65 +0.3
593,587 + cusS b0570 0.72 +1.1
593,611 - cusS b0570 0.73 -0.4
593,646 - cusS b0570 0.76 +0.3
593,694 - cusS b0570 0.79 +0.3
593,694 - cusS b0570 0.79 +0.2
593,704 + cusS b0570 0.80 -1.1
593,710 - cusS b0570 0.80 +0.2
593,887 + +0.3
594,000 + +0.1
594,000 + +0.2
594,001 + -0.1
594,001 - +0.8
594,149 - cusR b0571 0.24 -1.1
594,149 - cusR b0571 0.24 +0.2
594,200 - cusR b0571 0.32 -0.5
594,200 - cusR b0571 0.32 -0.6
594,209 - cusR b0571 0.33 -0.1
594,209 - cusR b0571 0.33 +0.4
594,219 - cusR b0571 0.35 +0.1
594,219 - cusR b0571 0.35 +0.2
594,343 - cusR b0571 0.53 +0.2
594,460 - cusR b0571 0.70 +0.4
594,460 - cusR b0571 0.70 +0.2
594,474 - cusR b0571 0.72 -0.3
594,515 - cusR b0571 0.78 -0.3
594,557 + cusR b0571 0.84 -0.2
594,557 + cusR b0571 0.84 -0.1
594,723 - -0.5
594,743 - -0.8
594,895 - +1.1
594,952 - -0.1

Or see this region's nucleotide sequence