| Condition | Gene | Description | Fitness | Cons. |
|---|
| Cytosine | PfGW456L13_2445 | Cytosine deaminase (EC 3.5.4.1) | -2.5 | Yes |
| Cytosine | PfGW456L13_2446 | Possible oxidoreductase | +1.8 | |
| Cytosine | PfGW456L13_3503 | Beta-ureidopropionase (EC 3.5.1.6) (from data) | -1.7 | |
| Cytosine | PfGW456L13_3505 | uridine/cytosine permease (from data) | -1.1 | Yes |
| Cytosine | PfGW456L13_3506 | Dihydropyrimidinase (EC 3.5.2.2) (from data) | -1.3 | Yes |
| D-Alanine | PfGW456L13_1700 | Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4) | -1.3 | Yes |
| D-Serine | PfGW456L13_1057 | Membrane-bound lytic murein transglycosylase A precursor (EC 3.2.1.-) | -1.6 | |
| D-Serine | PfGW456L13_1142 | Protein rarD | -4.4 | Yes |
| D-Serine | PfGW456L13_117 | Oxidoreductase, short chain dehydrogenase/reductase family | -1.6 | Yes |
| D-Serine | PfGW456L13_2223 | Glutamate synthase [NADPH] large chain (EC 1.4.1.13) | -1.5 | |
| D-Serine | PfGW456L13_2252 | Aspartate aminotransferase (EC 2.6.1.1) | -1.2 | Yes |
| D-Serine | PfGW456L13_3647 | D-serine dehydratase transcriptional activator | -4.9 | Yes |
| D-Serine | PfGW456L13_3648 | D-serine ammonia-lyase (EC 4.3.1.18) (from data) | -4.7 | Yes |
| D-Serine | PfGW456L13_3649 | D-serine permease (from data) | -1.6 | |
| D-Serine | PfGW456L13_375 | transport permease protein of gamma-aminobutyrate | +1.5 | |
| D-Serine | PfGW456L13_4001 | Polysaccharide export lipoprotein Wza | -1.7 | |
| D-Serine | PfGW456L13_4002 | YjbF outer membrane lipoprotein | -1.5 | |
| D-Serine | PfGW456L13_4790 | D-serine/D-alanine/glycine transporter | +2.8 | |
| Gly-DL-Asp | PfGW456L13_1868 | Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) | -1.5 | |
| Gly-DL-Asp | PfGW456L13_3909 | Ribose operon repressor | +1.3 | Yes |
| Gly-DL-Asp | PfGW456L13_5051 | Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) | -2.3 | Yes |
| Gly-DL-Asp | PfGW456L13_5053 | Outer membrane porin, OprD family | +2.4 | Yes |
| Gly-DL-Asp | PfGW456L13_5054 | Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) | +5.9 | Yes |
| Gly-DL-Asp | PfGW456L13_5055 | Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) | -2.1 | Yes |
| Gly-DL-Asp | PfGW456L13_5056 | Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) | -2.7 | Yes |
| Gly-DL-Asp | PfGW456L13_5058 | Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) | -2.8 | Yes |
| Gly-Glu | PfGW456L13_5051 | Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) | -2.1 | Yes |
| Gly-Glu | PfGW456L13_5053 | Outer membrane porin, OprD family | +1.8 | Yes |
| Gly-Glu | PfGW456L13_5054 | Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) | +4.4 | Yes |
| Gly-Glu | PfGW456L13_5055 | Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) | -2.4 | Yes |
| Gly-Glu | PfGW456L13_5056 | Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) | -2.3 | Yes |
| Gly-Glu | PfGW456L13_5057 | Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) | -1.9 | Yes |
| Gly-Glu | PfGW456L13_5058 | Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) | -2.0 | Yes |
| Glycine | PfGW456L13_161 | putative transporter, required for glycine utilization (from data) | -4.8 | Yes |
| Glycine | PfGW456L13_1866 | Aminomethyltransferase (EC 2.1.2.10) (from data) | -3.9 | Yes |
| Glycine | PfGW456L13_1868 | Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) | -4.8 | Yes |
| Glycine | PfGW456L13_1870 | Sigma-54 dependent transcriptional regulator/sensory box protein | -1.7 | Yes |
| Glycine | PfGW456L13_2685 | Glycine hydroxymethyltransferase (EC 2.1.2.1) (from data) | -1.4 | |
| Glycine | PfGW456L13_4791 | Transposase and inactivated derivatives | +1.2 | |
| L-Arginine | PfGW456L13_1971 | Succinylornithine transaminase (EC 2.6.1.81) | -4.4 | Yes |
| L-Arginine | PfGW456L13_1974 | Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) (from data) | -3.9 | Yes |
| L-Arginine | PfGW456L13_1977 | Succinylglutamate desuccinylase (EC 3.5.1.96) (from data) | -3.5 | |
| L-Arginine | PfGW456L13_3518 | Quino(hemo)protein alcohol dehydrogenase, PQQ-dependent (EC 1.1.99.8) | +1.2 | |
| L-Arginine | PfGW456L13_821 | Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog | -1.6 | |
| L-Asparagine | PfGW456L13_740 | L-asparaginase (EC 3.5.1.1) (from data) | -1.1 | Yes |
| L-Aspartic Acid | PfGW456L13_1891 | DNA-binding response regulator GltR, controls specific porins for the entry of glucose | -1.7 | |
| L-Aspartic Acid | PfGW456L13_1892 | Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster | -1.5 | |
| L-Aspartic Acid | PfGW456L13_1894 | ABC transporter for D-Galactose and D-Glucose, periplasmic substrate-binding component (from data) | -1.5 | |
| L-Aspartic Acid | PfGW456L13_1895 | ABC transporter for D-Galactose and D-Glucose, permease component 1 (from data) | -1.7 | |
| L-Aspartic Acid | PfGW456L13_1896 | ABC transporter for D-Galactose and D-Glucose, permease component 2 (from data) | -2.0 | |
| L-Aspartic Acid | PfGW456L13_1897 | ABC transporter for D-Galactose and D-Glucose, ATPase component (from data) | -1.9 | |
| L-Aspartic Acid | PfGW456L13_4652 | Kup system potassium uptake protein | -1.5 | |
| L-Glutamine | PfGW456L13_4778 | Transcriptional activator MetR | -1.2 | Yes |
| L-Glutamine | PfGW456L13_54 | Probable transmembrane protein | -1.7 | |
| L-Histidine | PfGW456L13_316 | N-formylglutamate deformylase (EC 3.5.1.68) (from data) | -4.8 | Yes |
| L-Histidine | PfGW456L13_317 | Imidazolonepropionase (EC 3.5.2.7) (from data) | -3.7 | Yes |
| L-Histidine | PfGW456L13_320 | Histidine ammonia-lyase (EC 4.3.1.3) (from data) | -2.3 | Yes |
| L-Histidine | PfGW456L13_326 | Urocanate hydratase (EC 4.2.1.49) (from data) | -1.7 | Yes |
| L-Histidine | PfGW456L13_330 | Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) | -4.4 | Yes |
| L-Histidine | PfGW456L13_4805 | Glucose dehydrogenase, PQQ-dependent (EC 1.1.5.2) | -1.2 | |
| L-Histidine | PfGW456L13_567 | Glycine cleavage system transcriptional activator | -1.2 | |
| L-Isoleucine | PfGW456L13_2982 | 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (from data) | -2.4 | Yes |
| L-Isoleucine | PfGW456L13_2983 | 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) | -1.4 | Yes |
| L-Isoleucine | PfGW456L13_3238 | Transcriptional regulator, AraC family | -2.0 | Yes |
| L-Isoleucine | PfGW456L13_3540 | branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) | -2.3 | Yes |
| L-Isoleucine | PfGW456L13_3541 | branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data) | -1.9 | Yes |
| L-Isoleucine | PfGW456L13_3542 | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) | -1.9 | Yes |
| L-Isoleucine | PfGW456L13_3543 | Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) | -1.4 | Yes |
| L-Isoleucine | PfGW456L13_4115 | 2-methylaconitate cis-trans isomerase | -3.9 | |
| L-Lysine | PfGW456L13_1164 | Coenzyme PQQ synthesis protein F (EC 3.4.99.-) | -1.3 | |
| L-Lysine | PfGW456L13_1170 | 5-aminopentanamidase (EC 3.5.1.30) (from data) | -2.9 | Yes |
| L-Lysine | PfGW456L13_1171 | Lysine 2-monooxygenase (EC 1.13.12.2) (from data) | -4.9 | Yes |
| L-Lysine | PfGW456L13_1172 | Transcriptional regulator, AsnC family | -5.1 | Yes |
| L-Lysine | PfGW456L13_1891 | DNA-binding response regulator GltR, controls specific porins for the entry of glucose | -2.5 | |
| L-Lysine | PfGW456L13_1892 | Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster | -3.1 | |
| L-Lysine | PfGW456L13_1894 | ABC transporter for D-Galactose and D-Glucose, periplasmic substrate-binding component (from data) | -3.2 | |
| L-Lysine | PfGW456L13_1895 | ABC transporter for D-Galactose and D-Glucose, permease component 1 (from data) | -3.0 | |
| L-Lysine | PfGW456L13_1896 | ABC transporter for D-Galactose and D-Glucose, permease component 2 (from data) | -3.5 | |
| L-Lysine | PfGW456L13_1897 | ABC transporter for D-Galactose and D-Glucose, ATPase component (from data) | -3.5 | |
| L-Lysine | PfGW456L13_2411 | Acetyl-CoA C-acetyltransferase (EC 2.3.1.9) (from data) | -1.5 | Yes |
| L-Lysine | PfGW456L13_3215 | HTH-type transcriptional regulator BetI | -4.8 | Yes |
| L-Lysine | PfGW456L13_3513 | Coenzyme PQQ synthesis protein E | -1.2 | |
| L-Lysine | PfGW456L13_3519 | SoxH protein, homolog | -1.9 | |
| L-Lysine | PfGW456L13_377 | Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) | -1.1 | |
| L-Lysine | PfGW456L13_378 | Arginine ABC transporter, permease protein ArtQ | -1.6 | Yes |
| L-Lysine | PfGW456L13_379 | Amino acid ABC transporter, permease protein | -1.2 | |
| L-Lysine | PfGW456L13_3872 | Transcriptional regulator, AraC family | -4.1 | |
| L-Lysine | PfGW456L13_495 | Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) (from data) | -1.3 | |
| L-Lysine | PfGW456L13_553 | L-carnitine dehydratase/bile acid-inducible protein F | -1.7 | |
| L-Lysine | PfGW456L13_554 | Glutaryl-CoA dehydrogenase (EC 1.3.99.7) | -2.0 | Yes |
| L-Lysine | PfGW456L13_555 | Glycine cleavage system transcriptional activator | -1.2 | Yes |
| L-Phenylalanine | PfGW456L13_2935 | 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (from data) | -2.0 | Yes |
| L-Phenylalanine | PfGW456L13_3955 | Transcriptional regulator, TetR family | +2.1 | |
| L-Phenylalanine | PfGW456L13_4222 | Transcriptional regulator, TetR family | +3.0 | Yes |
| L-Phenylalanine | PfGW456L13_4393 | Phenylalanine hydroxylase transcriptional activator PhhR | -2.5 | Yes |
| L-Phenylalanine | PfGW456L13_4394 | Phenylalanine 4-monooxygenase (EC 1.14.16.1) (from data) | -1.6 | Yes |
| L-Phenylalanine | PfGW456L13_4396 | tyrosine aminotransferase (EC 2.6.1.57) (from data) | -2.1 | Yes |
| L-Phenylalanine | PfGW456L13_4977 | FolM Alternative dihydrofolate reductase 1 | +1.3 | |
| L-Proline | PfGW456L13_1534 | FIG00955330: hypothetical protein | -1.2 | |
| L-Proline | PfGW456L13_2172 | S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase | -2.2 | |
| L-Proline | PfGW456L13_859 | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | -2.1 | |
| L-Serine | PfGW456L13_4954 | L-serine ammonia-lyase (EC 4.3.1.17) (from data) | -4.7 | Yes |
| L-Threonine | PfGW456L13_1114 | L-threonine aldolase (EC 4.1.2.5) (from data) | -2.5 | Yes |
| L-Threonine | PfGW456L13_1115 | Membrane protein, putative | +3.8 | |
| L-Threonine | PfGW456L13_1777 | GGDEF domain/EAL domain protein | +1.1 | |
| L-Threonine | PfGW456L13_1866 | Aminomethyltransferase (EC 2.1.2.10) (from data) | -2.0 | Yes |
| L-Threonine | PfGW456L13_1868 | Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) | -2.7 | Yes |
| L-Threonine | PfGW456L13_1869 | glycine cleavage system H protein (EC 1.4.1.27) (from data) | -2.6 | Yes |
| L-Threonine | PfGW456L13_1870 | Sigma-54 dependent transcriptional regulator/sensory box protein | -1.6 | Yes |
| L-Tryptophan | PfGW456L13_4288 | Kynureninase (EC 3.7.1.3) (from data) | -1.2 | Yes |
| L-Tryptophan | PfGW456L13_4591 | 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) (from data) | -1.7 | |
| L-Tryptophan | PfGW456L13_4592 | 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) (from data) | -1.7 | |
| L-Tryptophan | PfGW456L13_4594 | Pca regulon regulatory protein PcaR | -1.2 | |
| L-Valine | PfGW456L13_229 | Na(+)/H(+) antiporter | +1.3 | |
| L-Valine | PfGW456L13_2542 | Major facilitator family transporter | +1.8 | |
| L-Valine | PfGW456L13_2568 | 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) | -1.0 | |
| L-Valine | PfGW456L13_2985 | isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) | -2.7 | Yes |
| L-Valine | PfGW456L13_2986 | 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) | -2.5 | Yes |
| L-Valine | PfGW456L13_3031 | Threonine dehydratase biosynthetic (EC 4.3.1.19) | -4.5 | |
| L-Valine | PfGW456L13_3540 | branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) | -4.3 | Yes |
| L-Valine | PfGW456L13_3541 | branched-chain alpha-ketoacid dehydrogenase, E1 component beta subunit (EC 1.2.4.4) (from data) | -3.8 | Yes |
| L-Valine | PfGW456L13_3542 | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) | -3.8 | Yes |
| L-Valine | PfGW456L13_3543 | Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) | -4.9 | |
| L-Valine | PfGW456L13_3955 | Transcriptional regulator, TetR family | +1.5 | |
| L-Valine | PfGW456L13_4115 | 2-methylaconitate cis-trans isomerase | -3.4 | |
| L-Valine | PfGW456L13_4117 | 2-methylcitrate synthase (EC 2.3.3.5) | -1.8 | |
| L-Valine | PfGW456L13_5147 | Transcriptional regulator, LysR family | -1.0 | Yes |
| L-Valine | PfGW456L13_910 | Transcriptional regulator, AsnC family | -1.7 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_134 | Protein containing transglutaminase-like domain, putative cysteine protease | -1.2 | |
| N-Acetyl-D-Glucosamine | PfGW456L13_2803 | Glyceraldehyde-3-phosphate dehydrogenase, putative | -1.2 | |
| N-Acetyl-D-Glucosamine | PfGW456L13_4830 | N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) (from data) | -5.1 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_4831 | Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) (from data) | -2.9 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_4832 | PTS system, glucose-specific IIA component / Phosphotransferase system, phosphocarrier protein HPr / Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) | -4.8 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_4833 | PTS system, N-acetylglucosamine-specific IIA component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) | -4.6 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_750 | Aldose 1-epimerase | -1.6 | Yes |
| N-Acetyl-D-Glucosamine | PfGW456L13_855 | Autolysis response regulater LytR | -1.4 | |
| Putrescine Dihydrochloride | PfGW456L13_805 | gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.99); 4-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54) (from data) | -3.3 | Yes |
| Putrescine Dihydrochloride | PfGW456L13_925 | Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) (from data) | -5.0 | Yes |
| Sodium nitrate | PfGW456L13_2114 | Molybdenum cofactor biosynthesis protein MoaA | -1.5 | Yes |
| Sodium nitrate | PfGW456L13_2272 | Molybdopterin-guanine dinucleotide biosynthesis protein MobA | -1.3 | Yes |
| Sodium nitrate | PfGW456L13_2274 | Molybdopterin biosynthesis protein MoeA | -1.2 | Yes |
| Sodium nitrate | PfGW456L13_4098 | Response regulator NasT | -5.2 | Yes |
| Sodium nitrate | PfGW456L13_4101 | Nitrite reductase (NAD(P)H) (EC 1.7.1.4) (from data) | -4.3 | Yes |
| Sodium nitrate | PfGW456L13_4103 | Nitrate reductase (EC 1.7.99.4) (from data) | -3.0 | Yes |
| Sodium nitrate | PfGW456L13_4778 | Transcriptional activator MetR | -2.7 | |
| Sodium nitrate | PfGW456L13_4947 | Permease of the drug/metabolite transporter (DMT) superfamily | -2.9 | |
| Sodium nitrate | PfGW456L13_4948 | Transcriptional regulator, AraC family | -1.8 | |
| Uridine | PfGW456L13_1662 | Heavy metal sensor histidine kinase | -2.9 | Yes |
| Uridine | PfGW456L13_2 | Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) | -1.3 | Yes |
| Uridine | PfGW456L13_3 | Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) | -2.7 | Yes |
| Uridine | PfGW456L13_3503 | Beta-ureidopropionase (EC 3.5.1.6) (from data) | -3.8 | Yes |
| Uridine | PfGW456L13_3505 | uridine/cytosine permease (from data) | -3.1 | Yes |
| Uridine | PfGW456L13_3506 | Dihydropyrimidinase (EC 3.5.2.2) (from data) | -3.9 | Yes |
| Uridine | PfGW456L13_3507 | Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism | -4.6 | Yes |
| Uridine | PfGW456L13_3508 | Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) | -3.5 | Yes |
| Uridine | PfGW456L13_4 | LysR family transcriptional regulator PA0133 | -2.1 | Yes |