Pairwise Alignments
Query, 1934 a.a., alpha-2-macroglobulin from Pseudomonas simiae WCS417
Subject, 1652 a.a., alpha2-macroglobulin from Escherichia coli ECOR38
Score = 279 bits (714), Expect = 2e-78
Identities = 385/1590 (24%), Positives = 633/1590 (39%), Gaps = 201/1590 (12%)
Query: 439 FLSEGALLSLNGEKRLGFMARGVPGAHVEIARLLPNQLQHLVDQSSGSFARPNFGNEYFD 498
F S G+LL + L MA V V R+ P L + Q R + N D
Sbjct: 170 FASRGSLLPGKVIEGLPVMALNVNNVDVNFFRVKPESLPAFISQWE---YRNSLANWQSD 226
Query: 499 RMVERQSL------DIPLSSNDPAKTVYDNVDLSHYLTANGGRRGIFVLKLSPQDDPAQR 552
++++ L D+ + N K + D+ A G+++ ++ +
Sbjct: 227 KLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQA-----GVYLAVMN-------Q 274
Query: 553 TFEYDRGSTSDLRFIVVTDLGIIAKRSSDGSHDVYVQSIGNGSPVADAQVDIIGRNGLPV 612
YD + + L ++D+G+ A R + D++ QS+ NG+ +V ++ G +
Sbjct: 275 AGRYDYSNPATL--FTLSDIGVSAHRYHNRL-DIFTQSLENGAAQQGIEVSLLNEKGQTL 331
Query: 613 SSGHTDGEGHAHFAKLDELRREKTPLMYVVTRGNDQSFLPIARQSQQLDLSRFDVGGLEE 672
+ +D +GH +L +K + + + + L + + LDL+ F++ G
Sbjct: 332 TQATSDAQGHV------QLENDKNAALLLARKDGQTTLLDLKLPA--LDLAEFNIAGAPG 383
Query: 673 DGAIDRLSAYLFTDRGLYRPGETAHLGMIVRSGNWKGALQGLPVELQITDPRGLEVIRQP 732
++F R LYRPGET L ++R + K AL P++L + P G +V+R
Sbjct: 384 YSK----QFFMFGPRDLYRPGETVILNGLLRDADGK-ALPDQPIKLDVIKPDG-QVLRSV 437
Query: 733 LKLSASGFETFDFPSSEVAPAGEYTATLQLIGQKQTRTDLGSVSFKVRDFEPDRMKVSLS 792
+ +G F +P A G + G Q R F V DF P+RM ++L+
Sbjct: 438 VSQPENGLYHFTWPLDSNAATGMWHIRANT-GDNQYRM----WDFHVEDFMPERMALNLT 492
Query: 793 LHDTPVQGWIPPDQVVAKVTAMHLFGAPASGRRVTAKMSLSPTLAAFDRYPDYRFRLNDS 852
TP+ P D+V V +L+GAPA+G + ++ L P A P + F +
Sbjct: 493 GEKTPLT---PNDEVKFSVVGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAA 549
Query: 853 LEDATTEDLAETTVDDNGQAVLDLNLQ-RFANSTYRLQVMSQVFEAEGGRNVAAQSALLV 911
+ T D + T+DD G+ + Q + +S ++ + E+ GGR V ++ +
Sbjct: 550 ENLSRTLDEVQLTLDDKGRGEVSTESQWKEIHSPLQVIFQGSLLES-GGRPVTRRAEQAI 608
Query: 912 SSAPYLVGVKSQ------------DSLSYVAKDAPRQVQWLAVAPDLSPL--AVDGLTSE 957
A L G++ Q ++ D + V D + AV GL
Sbjct: 609 WPADALPGIRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVR 668
Query: 958 VVEHRYVSVLVKQSNGTYKYESRIKNISQPASPLVMTKEGAKQTLNTSTP---GDFTLQL 1014
++ R + ++ + K++ + L + A +T S P G + L++
Sbjct: 669 LIRERRDYYWNWSEDEGWQSQFDQKDLIENEQTLDLQ---ADETGKVSFPVEWGAYRLEV 725
Query: 1015 K---DANGNLLNQIDYSVAGHGNTSRSLERNAELQLRLDKPSYATGDEIAISIRAPYTGA 1071
K +A ++ YS + + ++ R + L+LDK SY GD I + I AP G
Sbjct: 726 KAPNEAVSSVRFWAGYSWQDNSDGGGAV-RPDRVTLKLDKASYRPGDTIKLHIAAPTAGK 784
Query: 1072 GLITIERDKVYTQQWFKADSTNSVQHIRVPAGLEGN---AYVNVQFVRDMGSAEVYMSPL 1128
G +E + W + D + +P N Y++ VR +
Sbjct: 785 GYAMVESSE-GPLWWQEIDVLAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKR 843
Query: 1129 SYGVVPFSINLDARRMALKVEGPAKIEPGQTLDIKVNADRPG-------RAVVYAVDEGI 1181
+ GV+ + + RR+ L +E P K+ P Q L +K+ A +V AVD G+
Sbjct: 844 AVGVLHLPLGDENRRLDLALETPTKMRPNQPLTVKIKASNKNGEMPKQVNVLVSAVDSGV 903
Query: 1182 LQVARYQTPDPLGFFFQKRALEVGTSQILDLILPEFSRLLSGAAPGGDTEGAL------A 1235
L + Y TPDP FF ++ I ++ R L+ GGD +
Sbjct: 904 LNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGR-LAALRFGGDGDELKRGGKPPV 962
Query: 1236 NHLNPFKRKHQPPV--AWWSGLVDLPAGETVLHYQVPDSFNGKLHLFAVAVDTDSVGVSE 1293
NH+N ++ P G V LP G+ FNG+L + A A D G +E
Sbjct: 963 NHVNIVAQQALPVTLNEQGEGSVTLPIGD----------FNGELRVMAQAWTADDFGSNE 1012
Query: 1294 TNTEVRGPIVITPNVPAFVAPGDVFNVSAGVFSNLDTTADVKFELQTSDGLKVQGDKGST 1353
+ V P++ N+P F+A GD ++ + + D + L S L++ D +
Sbjct: 1013 SKVIVAAPVIAELNMPRFMASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAA 1072
Query: 1354 LSLQPRKEGTAEFKIKV-------------------GETLGSADLRF-VAVLPDGKRIQV 1393
+ L P T ++ GET+ ++ + V P V
Sbjct: 1073 VELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTV 1132
Query: 1394 AETTSIRPLSEHRV-ALSLGRFDSASKELKPTRELFSQLRDVQLGVAASPLVWANGLKHY 1452
T+++P + A L F + E QL L PL A +K
Sbjct: 1133 NYGTALQPGETWAIPADGLQNFSPVTLE--------GQL----LLSGKPPLNIARYIKE- 1179
Query: 1453 LDDYGYACTEQLVSKAMPAL-----------IWGGNAPEAEQAFGSAVRMLRQRQNQAGG 1501
L Y Y C EQ S P+L I G + + + + L Q Q GG
Sbjct: 1180 LKAYPYGCLEQTASGLFPSLYTNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGG 1239
Query: 1502 FGLWAANPDVAPYASLYATDFLIEARERGLPVPEDLLVRSNAYLTDLANGP-------SE 1554
F LW N D + + Y DFL+ A E+G VP D + R N L P ++
Sbjct: 1240 FALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYAD 1299
Query: 1555 GL--SELRNRAYASYLLSRQGILVSGALSDIRERYENYFKDSWQNDLGAAYLAASYKLLK 1612
L S+ ++YA+ +L+RQ GAL +I E + LG A
Sbjct: 1300 NLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQLGVALKTMGD--AT 1357
Query: 1613 QDRQADTLFRKIPWRSLVDKWDSDGLYYDPLVHDAEHLHLLARHFPELMDYVPTTLLDKL 1672
+ +A L K P R+ KW D Y PL +A L LL + +L+ TLL+ L
Sbjct: 1358 RGEEAIALALKTP-RNDERKWLGD--YGSPLRDNALMLSLLEEN--KLLPDEQNTLLNTL 1412
Query: 1673 GKRLNEQRYNSL--SAALLL--RALDNYGQRAQSDMTLKATAWLGDKQQQLLEMAGQPPR 1728
++ +R+ S S AL L R + + + Q+ + A G+K + Q
Sbjct: 1413 SQQAFGERWLSTQESNALFLAARTVQDLPGKWQAQTSFSAEPLTGEKTLNSNLNSDQ--- 1469
Query: 1729 AAVPGATQKLVMEKSDGPAAFYMLSEAGFDKGAKLKPINNGLEIIHEYL--DLKGEPVST 1786
L + S + + +G+ + A L P NN L+I L D K + + +
Sbjct: 1470 ------LATLQVSNSGDQPLWLRVDASGYPQSAPL-PANNVLQIERHILGTDGKSKSLDS 1522
Query: 1787 VAVGDEFLVRLRLRATDRDQVQQVAVVDLLPGGVEPVYNLPPEPEAASSEDGEGEASEYV 1846
+ GD LV L+++A+ + V VVDLLP G+E + N +AS E GE +
Sbjct: 1523 LRSGDLVLVWLQVKAS--NSVPDALVVDLLPAGLE-LENQNLANGSASLEQSGGEVQNLL 1579
Query: 1847 EEDSQEEESWQAPIGETELSNWQPEYVDVRDDRVVLYGTALRDVG--TFVYRVRATNAGT 1904
+ Q ++++ RDDR V A+ + T VY RA GT
Sbjct: 1580 NQMQQA----------------SIKHIEFRDDRFVA-AVAVDEYQPVTLVYLARAVTPGT 1622
Query: 1905 FNTPPAYAEGMYETTLQGRGKVGQLEITQP 1934
+ P E MY + G L I +P
Sbjct: 1623 YQVPQPMVESMYVPQWRATGAAEDLLIVRP 1652