Pairwise Alignments
Query, 2139 a.a., peptide synthetase from Pseudomonas simiae WCS417
Subject, 1818 a.a., pyochelin synthetase from Pseudomonas simiae WCS417
Score = 651 bits (1680), Expect = 0.0
Identities = 393/909 (43%), Positives = 529/909 (58%), Gaps = 32/909 (3%)
Query: 1113 IVADLAQRHASFPMTEVQQAYWLGRDPSLVLGGVSCHFYREYDVEDLDLPRLQRALQRLI 1172
++AD AQRH FP+T+VQ AY LGR S G V+CH Y E LD +++ A RLI
Sbjct: 60 VLADPAQRHTPFPLTDVQNAYLLGRQSSFGYGNVACHGYLELSWPSLDPQQVELAWNRLI 119
Query: 1173 ERHEMLRAVFDHSGQARILQQVPAFVI----------GQGHASLDDLREHCAHRVFDPHQ 1222
RH+MLRAV G R+L V + + Q ++ +R+ +++
Sbjct: 120 ARHDMLRAVIASEGSQRVLADVAHYSLTIADLRGATRAQHQHTVQQIRQAMEQKLYPTEV 179
Query: 1223 WPLFDVQAVTHGRHTRLAISLDNLILDALSILRFYAELDALYREPDMALAPLALSFRDYQ 1282
WPLF+++ L S+D+LI D S + EL+ L + P AL L ++FRDY
Sbjct: 180 WPLFELRLSRSDNGDTLHFSMDSLIADWASAQLLFNELELLLQNPQAALPALDITFRDYL 239
Query: 1283 L--QCAAAPAELQAAQRFWQERLPQLPPHPQLPLAADPASLGRPRFERLQGQIDASAWQA 1340
L + + Q + +W R+ LP PQLP PRF+R +++ W A
Sbjct: 240 LAERSLLEGSRHQRDRDYWLTRIDALPAAPQLPTPLSGEDTREPRFQRHSARLEPQPWAA 299
Query: 1341 ILAKAQQQGLTASAVLLCAFAETLGRWSARPDLSLNLTLFDRRPLHPQVDQIMGDFTSLT 1400
+ + A ++ LT S V+L A+A TL RWS +P SLNLTL +R PLHPQVD+++GDFTS++
Sbjct: 300 LKSAASERSLTPSIVVLAAYAATLQRWSQQPAFSLNLTLLNRLPLHPQVDRLVGDFTSVS 359
Query: 1401 LLGYVPVAGERWVDRARRTQQSLGEALEHRCVGSVSLLRQLARGNGEQQVSMPVVFTSAL 1460
LL G + +AR+ L LEHR + ++R++ R G + +MPVVFTSA+
Sbjct: 360 LLQVNDPEGLDFTAQARQLGNQLFTDLEHRLFSGIQVMREIGRRRGREAAAMPVVFTSAI 419
Query: 1461 GVPNGTAAPVDGPFARQVFGLTQTPQVWLDHQVVEANGGIALNWDRVVGLFPEGLVETMF 1520
G+ G AP R G+TQTPQV LD QV++ G+ ++WD G+FP+GLV+ M
Sbjct: 420 GL--GIEAPPASQ-RRVGHGITQTPQVTLDCQVMDDANGLHIHWDVRQGVFPDGLVDDMQ 476
Query: 1521 AAYLHSLNWLA--EHAWDSAPPDLLPQAQAQRRAQLNAPGDRVPGDPTLHQGFFEQARQT 1578
A++ L LA AW+ LP Q + R NA +P LH G A +
Sbjct: 477 QAFVAELQLLALDPAAWEHPVQVPLPAWQQRERLAANATAAPLPTG-RLHDGLLAMAWEH 535
Query: 1579 PQSPALLWGEHGTLKYGELADRALRIAHSLMDAGVAPGDLVAVSLAKGPQQVACVLGILA 1638
P + A++ G+L Y LA+RAL +A +L +AG + VA+ + KG QV G+L
Sbjct: 536 PHALAVI-DASGSLTYAALAERALAVASALREAGCDAQEPVAILMPKGLDQVVAAYGVLL 594
Query: 1639 AGAAYLPVGVDQPLQRCQRILQQAGVTLMLAEH--DPQLPGVKHLNPSSALKAEPLAAPR 1696
AGAAYLP+ + P R R+L+ A V +L P P + S + A
Sbjct: 595 AGAAYLPLDSNAPAARRDRVLRSAKVRHVLGHSLAQPHTPLPETSQWHSVDRLPSAGADF 654
Query: 1697 PLAAGE---LAYVIYTSGSTGQPKGVEITHRAAMNTVADINRRYDVQATDRGLALSALDF 1753
L G LAYVIYTSGSTG+PKGV I+HRAA+NTV DINRR++V A DR L L+ L F
Sbjct: 655 ELLEGSPDHLAYVIYTSGSTGEPKGVMISHRAALNTVQDINRRFEVNADDRVLGLAQLSF 714
Query: 1754 DLSVYDLFGLLSVGGALVLIDEDQRRDARAWLKALQQHRVTLWNSVPALLDMLLE-ANAQ 1812
DLSVYDLFG L+VGG LVL D + D W + +Q+H+VTLWNSVPA L ML + +A+
Sbjct: 715 DLSVYDLFGPLAVGGTLVLPDPARGADPSHWAELVQRHQVTLWNSVPAQLHMLADYLHAE 774
Query: 1813 DRQRLDLKVALLSGDWIGLDLPQRLQDQAPSCRFIALGGATEAAIWSNHFEVQPPLPGWR 1872
R L++ALLSGDWI L+LP +L+ P + + LGGATEA+IWSN + P WR
Sbjct: 775 PRPLDSLRLALLSGDWIPLNLPPQLKALLPELKLVGLGGATEASIWSNLHPIGAIDPAWR 834
Query: 1873 SIPYGVPLTNQAYRVVDALGRDCPDWVTGELWIGGAGVARGYRHAPQLNAERF----VDG 1928
SIPYG+PL NQ +RV+D RD P WV G+L+I G G+A+GY L+ RF +DG
Sbjct: 835 SIPYGLPLANQGFRVLDHHWRDAPTWVPGDLYITGVGLAQGYLGDMDLSDARFFPHPLDG 894
Query: 1929 --WYRTGDLGRYHPDGLLEFLGRADSQVKIGGHRIELGEIEAALARHPCVNSAVALVVDN 1986
YRTGD GRY P G LEFLGR D QVKI GHR+ELGE+EAAL P V+SAV+L V
Sbjct: 895 QRLYRTGDRGRYLPGGELEFLGREDGQVKIRGHRVELGEVEAALLATPGVDSAVSL-VSG 953
Query: 1987 RLMAAVTAS 1995
L+A VTA+
Sbjct: 954 DLLAFVTAA 962
Score = 596 bits (1536), Expect = e-173
Identities = 373/918 (40%), Positives = 499/918 (54%), Gaps = 47/918 (5%)
Query: 94 PFELAPMQHAYWIGRAPGQQLGGVAAHFYNEFDGQDVDPIRLEAAVRALLARHPMLRAQF 153
PF L +Q+AY +GR G VA H Y E +DP ++E A L+ARH MLRA
Sbjct: 70 PFPLTDVQNAYLLGRQSSFGYGNVACHGYLELSWPSLDPQQVELAWNRLIARHDMLRAVI 129
Query: 154 LDDGRQQILAHSPWPGLTVHDLRQASAEQVQQRLAALRAELSHRQLAVEQGQVLDIQLSL 213
+G Q++LA LT+ DLR A+ Q Q + +R + + E + +++LS
Sbjct: 130 ASEGSQRVLADVAHYSLTIADLRGATRAQHQHTVQQIRQAMEQKLYPTEVWPLFELRLSR 189
Query: 214 LPNGTRLHLNLDMLAADALSLRTLLGDLVQLYRQHP---LPALDYNFARYLADLRQEQNS 270
NG LH ++D L AD S + L +L +L Q+P LPALD F YL + S
Sbjct: 190 SDNGDTLHFSMDSLIADWASAQLLFNEL-ELLLQNPQAALPALDITFRDYLL----AERS 244
Query: 271 AEQRDRHQQARDYWLQRLDQLPGAPSLPIKPQGDDRQVCR--RHHW-LPPSERQAFERQA 327
+ RHQ+ RDYWL R+D LP AP LP G+D + R RH L P A + A
Sbjct: 245 LLEGSRHQRDRDYWLTRIDALPAAPQLPTPLSGEDTREPRFQRHSARLEPQPWAALKSAA 304
Query: 328 REHGLTPAMALAAVFCEALGAWCDTPELLLNLPLFNRTPLHADVDRLVGDFTSSILLAWD 387
E LTP++ + A + L W P LNL L NR PLH VDRLVGDFTS LL +
Sbjct: 305 SERSLTPSIVVLAAYAATLQRWSQQPAFSLNLTLLNRLPLHPQVDRLVGDFTSVSLLQVN 364
Query: 388 GRVAGTFAARATALQRRFHSDVAHSAFSGLEVLRELSRQRGEQVLA-PVVYTSALGLGEL 446
F A+A L + +D+ H FSG++V+RE+ R+RG + A PVV+TSA+GLG
Sbjct: 365 DPEGLDFTAQARQLGNQLFTDLEHRLFSGIQVMREIGRRRGREAAAMPVVFTSAIGLG-- 422
Query: 447 FAEGVQASFGQPAWIISQGPQVWLDAQVTELDGGILVNLDAREGLFAGGVLDGMFKAYTD 506
E AS + I+Q PQV LD QV + G+ ++ D R+G+F G++D M +A+
Sbjct: 423 -IEAPPASQRRVGHGITQTPQVTLDCQVMDDANGLHIHWDVRQGVFPDGLVDDMQQAFVA 481
Query: 507 LLQRLCFDPASWHQAPPALVPAAQLAVRQAVQGQRVALPVKRLHEAFFAQARLTPTLPAL 566
LQ L DPA+W +PA Q R A LP RLH+ A A P A+
Sbjct: 482 ELQLLALDPAAWEHPVQVPLPAWQQRERLAANATAAPLPTGRLHDGLLAMAWEHPHALAV 541
Query: 567 LQGNPPVISYGELAERALQLAAYLEDQGIRRGDVVALQLPKGPEQVIAVLGILACSATYL 626
+ + ++Y LAERAL +A+ L + G + VA+ +PKG +QV+A G+L A YL
Sbjct: 542 IDASGS-LTYAALAERALAVASALREAGCDAQEPVAILMPKGLDQVVAAYGVLLAGAAYL 600
Query: 627 PIGIDQPEARCQKICDGSGARLLL--------------------KALPSEGPALEAPRPG 666
P+ + P AR ++ + R +L LPS G E G
Sbjct: 601 PLDSNAPAARRDRVLRSAKVRHVLGHSLAQPHTPLPETSQWHSVDRLPSAGADFELLE-G 659
Query: 667 AISDLAYILYTSGSTGDPKGVEISHLAAANTLDDLQRRLQLTADDRILALSALEFDLSVF 726
+ LAY++YTSGSTG+PKGV ISH AA NT+ D+ RR ++ ADDR+L L+ L FDLSV+
Sbjct: 660 SPDHLAYVIYTSGSTGEPKGVMISHRAALNTVQDINRRFEVNADDRVLGLAQLSFDLSVY 719
Query: 727 DLFAALSTGAAVIGIEPEAQRDALRWRELALLHHASVLNCVPALLDMLLGCAAADARL-- 784
DLF L+ G ++ +P D W EL H ++ N VPA L ML A+ R
Sbjct: 720 DLFGPLAVGGTLVLPDPARGADPSHWAELVQRHQVTLWNSVPAQLHMLADYLHAEPRPLD 779
Query: 785 PLRAVLLGGDKVAPDLAPRLWAQAPGCRFMALGGATEAAIHSTLFEAFPGQPLQWHCLPY 844
LR LL GD + +L P+L A P + + LGGATEA+I S L P W +PY
Sbjct: 780 SLRLALLSGDWIPLNLPPQLKALLPELKLVGLGGATEASIWSNLHPIGAIDP-AWRSIPY 838
Query: 845 GKPLDNVSLRIVDHQGHDCPDWVAGELWIGGAGVAEGYRGDRVRSAERFVDY--QGQRWY 902
G PL N R++DH D P WV G+L+I G G+A+GY GD S RF + GQR Y
Sbjct: 839 GLPLANQGFRVLDHHWRDAPTWVPGDLYITGVGLAQGYLGDMDLSDARFFPHPLDGQRLY 898
Query: 903 RTGDRARYHPDGNVEFLGRTDFQLKLHGYRIEAGEVEQALLACPGVEHAVVLLAGQQLAA 962
RTGDR RY P G +EFLGR D Q+K+ G+R+E GEVE ALLA PGV+ AV L++G LA
Sbjct: 899 RTGDRGRYLPGGELEFLGREDGQVKIRGHRVELGEVEAALLATPGVDSAVSLVSGDLLAF 958
Query: 963 VVRQAHGPAQPAPIDLPG 980
V A+ P LPG
Sbjct: 959 VT-----AARAEPEPLPG 971
Score = 72.8 bits (177), Expect = 5e-16
Identities = 62/194 (31%), Positives = 90/194 (46%), Gaps = 22/194 (11%)
Query: 940 QALLACPGVEHAVVLLAGQQLAAVVRQAHGPAQPAPIDL--PGLAERLPAYMIPTFILGC 997
+ L A P +H + L Q AA + Q +D LA+RLP YM+P +
Sbjct: 1315 ECLPALPQADHPLAALGMQVFAARFKAG---VQRLSVDSLRRALAQRLPDYMLPAHLQVL 1371
Query: 998 AQLPLTGNGKVDRKALHAWL----AQHSPAQQANLTPPCGDIEQQVARAWQQLLGCSEVC 1053
+LPLT NGKVDRK L W AQ S +Q+A P + ++ R W LG +++
Sbjct: 1372 DRLPLTANGKVDRKTLAGWRPAADAQASSSQEA----PSDPLTAELCRVWADALGLAQIG 1427
Query: 1054 REHNFFALGGDSLSATRLVRLLAEHGLGGAR-------IAQVFAKPVLAQFCTTLHQQVR 1106
E +F+ G DSL R+ L E L A+ + Q+ +P +A L+Q +
Sbjct: 1428 VEDSFYEKGADSLILARVAGQLREQ-LPQAQSLSYDTLLRQMLNEPNVAALARLLNQG-K 1485
Query: 1107 AESARTIVADLAQR 1120
AR + AQR
Sbjct: 1486 TTPARVAASGEAQR 1499
Score = 65.5 bits (158), Expect = 7e-14
Identities = 51/158 (32%), Positives = 70/158 (44%), Gaps = 8/158 (5%)
Query: 1964 GEIEAAL--ARHPCVNSAVALVVDNRLMAAVTASTCAEVLAQHLEQCLPAYMRPEQVLVL 2021
GE AL A HP +A+ + V A + L + L Q LP YM P + VL
Sbjct: 1314 GECLPALPQADHPL--AALGMQVFAARFKAGVQRLSVDSLRRALAQRLPDYMLPAHLQVL 1371
Query: 2022 ERLPLNSNGKVDRRALLAPLTAAAQSRVALDEQPLSAGEHVIAELWQHLLKVPNVSRHDN 2081
+RLPL +NGKVDR+ L AA + E P + +W L + + D+
Sbjct: 1372 DRLPLTANGKVDRKTLAGWRPAADAQASSSQEAPSDPLTAELCRVWADALGLAQIGVEDS 1431
Query: 2082 FFRLGGDSLLATRFLEMLRSRLGVELPMGQLFGAASLL 2119
F+ G DSL+ R LR +LP Q +LL
Sbjct: 1432 FYEKGADSLILARVAGQLRE----QLPQAQSLSYDTLL 1465
Score = 36.2 bits (82), Expect = 5e-05
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
Query: 4 PSTSTAILLRQSLSDALGLPADQVPLEANLIEWGLDSVTLIRLAGQWRRQGLAAR----- 58
PS L + +DALGL Q+ +E + E G DS+ L R+AGQ R Q A+
Sbjct: 1405 PSDPLTAELCRVWADALGLA--QIGVEDSFYEKGADSLILARVAGQLREQLPQAQSLSYD 1462
Query: 59 --FADLVADPRLCAWLALLDTAPTATAPISTS 88
++ +P + A LL+ T A ++ S
Sbjct: 1463 TLLRQMLNEPNVAALARLLNQGKTTPARVAAS 1494