Pairwise Alignments

Query, 1021 a.a., multidrug transporter AcrB from Pseudomonas simiae WCS417

Subject, 1017 a.a., RND efflux transporter from Pseudomonas putida KT2440

 Score =  927 bits (2396), Expect = 0.0
 Identities = 480/1020 (47%), Positives = 676/1020 (66%), Gaps = 18/1020 (1%)

Query: 3    FNLSEWALRNRQIVLFLMILLAVVGTLSYSKLGQSEDPPFTFKAMVIKTNWPGATAQEVS 62
            FNLS+WAL+++  V +LM +  ++G  SY  LG+ EDP FT K MVI+T WPGAT  E  
Sbjct: 5    FNLSDWALKHQSFVWYLMFVSLLMGIFSYFNLGREEDPSFTIKTMVIQTRWPGATQDETL 64

Query: 63   RQVTERIEKKLMETGEYERIVSFSRPGESQVTFIARDSMHSAQIPELWYQVRKKISDIRQ 122
             QVT+RIEKKL E    +   S++RPGES V    RD+  +  IP++WYQVRKKI DIR 
Sbjct: 65   YQVTDRIEKKLEELDSLDYTKSYTRPGESTVYVYLRDTTKAKDIPDIWYQVRKKIQDIRG 124

Query: 123  TLPPDIQGPFFNDEFGTTFGNIYALTGDGFDYAVLKDYADRIQIQLQRVADVGKVELLGL 182
              P  IQGP FNDEFG  FG+IYA T DG     L+DY ++ + +++ V ++GK+EL+G 
Sbjct: 125  EFPAGIQGPGFNDEFGDVFGSIYAFTADGLTLRQLRDYVEQARAEVRDVPNIGKIELVGT 184

Query: 183  QDEKIWIELSNLKLATLGLPLAAVQQALQEQNAVSTAGFFETPSERVQLRVSGNFKTVEE 242
            QDE +++  S  KLA LG+    V QALQ QNAV+ AG  E   ER+ +R SG F + ++
Sbjct: 185  QDEVLYLNFSTRKLAALGIDQRQVMQALQAQNAVTPAGMIEAGPERISVRTSGQFASEKD 244

Query: 243  IRNFPIRVGDRTFRIGDVADIHRGFNDPPAPRMRYMGADAIGLAVAMRDGGDILVLGKAL 302
            ++   +R+ DR FR+ D+ADI RG+ DPP+P  RY G  AIGLA+ M+ GG+I V G AL
Sbjct: 245  LQTVNLRINDRFFRLADIADIERGYVDPPSPMFRYNGQTAIGLAIGMKAGGNIQVFGAAL 304

Query: 303  EGEFARLQKNLPAGMELRKVSDQPAAVKTSVGEFVQVLAEALAIVLLVSFFSLGVRTGMV 362
            +    ++ ++LP G+ +  VSDQ   VK +VG F   L EA+ IVL VSF SLGVR G+V
Sbjct: 305  KKRMDQVVQDLPVGVGVHTVSDQAVVVKQAVGGFTSALFEAVVIVLAVSFVSLGVRAGLV 364

Query: 363  VALAIPLVLAMTFATMYYLGIGLHKISLGALVLALGLLVDDAIIAVEMMAIKMEQGYDRL 422
            VA +IPLVLAM F  M Y GI + +ISLGAL++ALGLLVDDA+I VE+M  ++E G  + 
Sbjct: 365  VACSIPLVLAMVFVFMEYSGITMQRISLGALIIALGLLVDDAMITVEVMVTRLEMGESKE 424

Query: 423  KAASFAWTSTAFPMLTGTLITAAGFLPIATAQSSTGEYTRSIFQVVTIALLASWVAAVVF 482
            +AA+FA+TSTAFPMLTGTL+T AGF+PI    SS GEYT ++F V+ +AL+ SWV AV F
Sbjct: 425  QAATFAYTSTAFPMLTGTLVTVAGFVPIGLNASSAGEYTFTLFAVIAVALIVSWVVAVFF 484

Query: 483  VPYLGEKLLP-DLAKIHAAKHGTDGPDPYGTPFYQRVRRMVE----WCVRRRKTVIVLTL 537
             P LG  +L  D  K H A+ G             RV R  E    WC+R R   I+ T+
Sbjct: 485  APVLGVHILKGDKLKAHEAEPG-------------RVGRAFEGGLLWCMRNRWLTIIGTV 531

Query: 538  LLFIGSVALFRFVPQQFFPASGRLELMVDLKLAEGASLSNTADQVKRLEALLKEHAGIDN 597
            +LF  ++   RFV  QFFP+S R E++VDL L + AS+  T   V R EA +K+   + +
Sbjct: 532  VLFALAIFCMRFVQNQFFPSSDRPEILVDLNLPQNASIEETRKVVDRFEARIKDDPDLVH 591

Query: 598  YVAYVGTGSPRFYLPLDQQLPAASFAQFVVLAKTIEERESLRTWLIQTLNEQFPDLRSRV 657
            +  Y+G G+ RFYLPLDQQL    +AQ V+++K  EER+++   L + L+E+F  + + V
Sbjct: 592  WSTYIGQGAIRFYLPLDQQLQNPYYAQLVIVSKGFEERQAMMDRLQKILHEEFVGVGTNV 651

Query: 658  TRLENGPPVGYPVQFRVTGEHIEEVRALARKVAVKVRENPHVANVHLDWEEPSKIVYLNI 717
              LE GPPVG P+Q+RV+G  I++VR  A ++A  + +N H+  +  DW EP K++ + I
Sbjct: 652  QSLEMGPPVGRPIQYRVSGADIDQVRKHAIELATLLDQNEHIGEMIYDWNEPGKVLRVEI 711

Query: 718  DQDRARALGVSTANLSKFLQSSLTGSSVSQYREDNELIEILLRGTVHERTELSLLPSLAV 777
             QD+AR LG+S+ +++  + S ++G  ++Q  ++  L++++ R    ER     L +L +
Sbjct: 712  AQDKARQLGLSSEDVANVMNSIVSGVQITQVNDNIYLVDVVARAEDSERGSPDTLQNLQI 771

Query: 778  PTDNGKSVALSQIATLEYGFEEGIIWHRNRLPTVTIRADIYGKEQPATLVQQILPTLEGV 837
             T NG S+ L   AT+ Y  E+ ++W R+R PT+TI+A + G+ QP  LV Q+ P ++  
Sbjct: 772  LTPNGTSIPLLSFATVRYELEQPLVWRRDRKPTITIKASVNGEIQPTDLVAQLKPKIDEF 831

Query: 838  RAELPDGYLLDVGGTVEDSARGQNSVKAGVPLFIVVVLTLLMLQLRSFSRTAMVFLTAPL 897
             ++LP G+ +  GGTVE+SA+ Q  ++  +PL + ++ T LM+QL S  +  +V   APL
Sbjct: 832  ASKLPVGFEVATGGTVEESAKAQGPIRKVIPLMLFLMATFLMIQLHSVQKLFLVVSVAPL 891

Query: 898  GLIGVTLFLLVFRQPFGFVAMLGTIALSGMIMRNSVILVDQIEQDIKAGLAPWQAIIEAT 957
            GLIGV L L+    P GFVA+LG +AL+G+I+RNSVILV QI++    GL+PW A++EAT
Sbjct: 892  GLIGVVLALVPTGTPMGFVAILGILALAGIIIRNSVILVTQIDEFEAQGLSPWDAVVEAT 951

Query: 958  VRRFRPIVLTALAAVLAMIPLSRSVFFGPMAVAIMGGLIVATALTLLFLPALYAAWFRVK 1017
              R RPI+LTA AA L MIP++R VF+GPMA A++GG+IVAT LTLLFLPALY AW++++
Sbjct: 952  NHRRRPILLTAAAASLGMIPIAREVFWGPMAYAMIGGIIVATLLTLLFLPALYVAWYKIR 1011