Pairwise Alignments

Query, 554 a.a., Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) from Variovorax sp. SCN45

Subject, 423 a.a., Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex from Pseudomonas putida KT2440

 Score =  211 bits (538), Expect = 3e-59
 Identities = 140/429 (32%), Positives = 221/429 (51%), Gaps = 40/429 (9%)

Query: 122 VKVPDIGD-FKDVAVIELLVKVGDTVKAEQSLITVESDKASMEIPSSAAGVLKELKVKVG 180
           +K+PDIG+    V ++E  VKVGD +  +Q +  V +DKA++EIPS  +G +  L  + G
Sbjct: 6   IKMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPG 65

Query: 181 DTVNIG-DLIAV-LEGTAAAAPAPAQAAAAAPAAATTSAPAPAAP-------APAASPAA 231
           + + +G +LI + +EG+      P      APAA   + P P          APA   AA
Sbjct: 66  EVMAVGSELIRIEVEGSGNHVDVPQPKPVEAPAAPIAAKPEPQKDVKPAVYQAPANHEAA 125

Query: 232 AAAPHDPTVAPSGKLPHASPSVRKFARELGVPLEEVKGSGLKGRITQEDVQSFTKAVMSG 291
              P  P     G  P ASP+VRK A + G+ L  V GSG  GRI  ED+ +F     S 
Sbjct: 126 PIVPRQP-----GDKPLASPAVRKRALDAGIELRYVHGSGPAGRILHEDLDAFMSKPQS- 179

Query: 292 QVSTKASAAKAPAGGGDGAALGLIPWPKVDFTKFGTVERKDLSRIKKLSGANLHRNWVMI 351
                 +A +AP G                + K    E+  +  +++     +      +
Sbjct: 180 ------NAGQAPDG----------------YAKRTDSEQVPVIGLRRKIAQRMQDAKRRV 217

Query: 352 PHVTNNDEADITELEAFRVSTNKENEKSGVKVTMLAFVIKAVVAALKKFPEFNTSLDGDQ 411
            H +  +E D+T LEA R   N ++  S  K+T+L F+++A+V AL+ FP+ N + D + 
Sbjct: 218 AHFSYVEEIDVTALEALRQQLNSKHGDSRGKLTLLPFLVRALVVALRDFPQINATYDDEA 277

Query: 412 LVYKQY--YNIGFAADTPNGLVVPVLKDADKKGILQISAEMGELAKKARDGKLGSADMQG 469
            +  ++   ++G A    NGL+VPVL+ A+   +   + E+  LA  AR+ K    ++ G
Sbjct: 278 QIITRHGAVHVGIATQGDNGLMVPVLRHAEAGSLWANAGEISRLANAARNNKASREELSG 337

Query: 470 GCFSISSLGGIGGTHFTPIINAPEVAILGLSKSAMKPVWDGKQFVPRLTLPMSLSYDHRV 529
              +++SLG +GG   TP++N PEVAI+G+++   +PV    Q V R  + +S S+DHRV
Sbjct: 338 STITLTSLGALGGIVSTPVVNTPEVAIVGVNRMVERPVVIDGQIVVRKMMNLSSSFDHRV 397

Query: 530 IDGALAARF 538
           +DG  AA F
Sbjct: 398 VDGMDAALF 406



 Score = 69.7 bits (169), Expect = 2e-16
 Identities = 52/145 (35%), Positives = 72/145 (49%), Gaps = 22/145 (15%)

Query: 6   VKVPDIGD-FDEVAVIEVLVKVGDTVKAEQSLITVESDKASMEIPSSTAGVVKELKVEVG 64
           +K+PDIG+   +V ++E  VKVGD +  +Q +  V +DKA++EIPS  +G V  L  + G
Sbjct: 6   IKMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPG 65

Query: 65  GKVKEGSVVLVLEAEGAGAAAPAPAP-----AAAPAAAAP------------APAPAAAA 107
             +  GS ++ +E EG+G     P P      AAP AA P            APA   AA
Sbjct: 66  EVMAVGSELIRIEVEGSGNHVDVPQPKPVEAPAAPIAAKPEPQKDVKPAVYQAPANHEAA 125

Query: 108 P----APAAAPAASGPVEVKVPDIG 128
           P     P   P AS  V  +  D G
Sbjct: 126 PIVPRQPGDKPLASPAVRKRALDAG 150