Pairwise Alignments

Query, 949 a.a., Isoleucyl-tRNA synthetase (EC 6.1.1.5) from Variovorax sp. SCN45

Subject, 948 a.a., valine--tRNA ligase from Pseudomonas putida KT2440

 Score =  152 bits (383), Expect = 1e-40
 Identities = 221/923 (23%), Positives = 356/923 (38%), Gaps = 184/923 (19%)

Query: 31  EPGWVKEWNDEGRYHRLRDARHGAPK-FILHDGPPYANGQIHMGHAVNKILKDMITKARQ 89
           E  W   W  E  +     A  GA + + +   PP   G +HMGH  N  + D + + R+
Sbjct: 11  ETSWYNTWESENYF-----APQGAGESYTIMIPPPNVTGSLHMGHGFNNAIMDALIRFRR 65

Query: 90  LEGYDALYVPGWDCHGLPIENAIEKQF---GRN---LSRDEMQAKS---RAFATGQIAQQ 140
           ++G D L+ PG D  G+  +  +E+Q    G+N   L R++   K    +  + G I++Q
Sbjct: 66  MQGRDTLWQPGTDHAGIATQMLVERQLEAKGQNRHDLGREKFLEKVWEWKDQSGGNISRQ 125

Query: 141 MADFQRLGVLGEWDHPYKTMDFANEAGELRAFKRVIERGFVYRGLKPVYWCFDCGSSLAE 200
           +   +RLG   +W     TMD         AF R+ E G +YRG + V W     +++++
Sbjct: 126 I---RRLGSSVDWSRERFTMDDGLSEAVKEAFVRLHEDGLIYRGKRLVNWDTKLHTAISD 182

Query: 201 FEIEYADKKSQTIDVAFKAHEREKVLKAFGTDHTILGDIFAVIWTTTAWTIPANQAINLN 260
            E+E  D+K    ++ +   +  K         T  G  + V+ TT   T+  + A+ +N
Sbjct: 183 LEVENHDEKGHLWNLRYPLADGAK---------TAEGQDYLVVATTRPETLLGDAAVAVN 233

Query: 261 PELEYSLVDTERGLLILANSLVEMCMTRY-ALDGKVLATVKGEKLGGLEFEHPLYDVDAG 319
           P  E                       RY AL GK +             E PL      
Sbjct: 234 PNDE-----------------------RYQALIGKFV-------------ELPLVG---- 253

Query: 320 YKRLSPIYLADYATATDGTGLVHSSPAYGVDDFNSCIAHGVAYDDILNPVQGNGSYAPDF 379
             R  PI   DY     GTG V  +PA+  +D+     H +   +I +      S A  F
Sbjct: 254 --RRIPIIADDYCDPEFGTGCVKITPAHDFNDYEVGKRHNLPLLNIFDKNAFVLSSAQAF 311

Query: 380 PLFGGQN---------------IWKAVPVIVAALRDANRLLTTETITHSYPHCWRHKTPV 424
            L G  N                + A   IVA L     L++ +      P   R  T +
Sbjct: 312 NLDGSVNEQVDTQLPAQYANLDRFVARKQIVADLDAQGLLVSIDDHALKVPKGDRSGTVI 371

Query: 425 IYRAAAQWFVRMDEGEGVFTKDKAPKTLRQTALDAIE--QTSFYPENGKARLHDMIAGRP 482
                 QW+V             + K L + A+ A+E  +  F P+  +      +    
Sbjct: 372 EPWLTDQWYV-------------STKPLAEPAIAAVEDGRIQFVPKQYENMYFSWMRDIQ 418

Query: 483 DWCISRQRSWGVPIPFFLHKDSGELHPRTMEILDQAADIVEKGGIEAWSRVTVEEILGAE 542
           DWCISRQ  WG  IP + + ++G+++    E                   V  +  LGA+
Sbjct: 419 DWCISRQLWWGHRIPAW-YDEAGQVYVGRNE-----------------EEVRAKHKLGAD 460

Query: 543 DAPHYTKSTDILEVWFDSGSTFSHVLRGTHPTVHHDTGPEADLYLEGHDQHRGWFHSSLL 602
                 +  D+L+ WF SG      L     T         D+ + G D    W    ++
Sbjct: 461 VV--LRQDDDVLDTWFSSGLWTFSTLGWPEQTEFLKKFHSTDVLVTGFDIIFFWVARMIM 518

Query: 603 IACAL---ED---RAPYRGLLTHGFTVDAKGIKMSKSLKNGIDPQEISN----------- 645
           +   L   ED   + P++ +  HG   D +G KMSKS  N +DP +I +           
Sbjct: 519 LTMHLIKNEDGTPQVPFKTVYVHGLVRDGQGQKMSKSKGNVLDPLDIVDGITLDALLEKR 578

Query: 646 -------KLGSEIIRLWVA-----ASDYSGD-----------IAGDDKILARVVDAYR-- 680
                  KL  +I +   A      + Y  D              D K     V+ YR  
Sbjct: 579 TSGMMQPKLAEKIAKQTKAEFPEGIASYGTDALRFTFCSLASTGRDIKFDMGRVEGYRNF 638

Query: 681 --RIRNTLRFLLANTSDFDIEKDGVPLDQLFEIDRYALSRAAQFQAEILAHYKVYEFHPV 738
             +I N  R++L    D     +     +L   DR+ +S+  + +AE+    + + F   
Sbjct: 639 CNKIWNAARYVLDKGEDCGQNGEAY---ELSLADRWIISQLQRTEAEVTRQLEQFRFDLA 695

Query: 739 VAKLQIYCSEDLGGFYLDILKDRLY-TTAPGSLARRSAQTALWHISQAMLRWMAPFLSFT 797
              L  +       +YL++ K  L+   AP   AR + +T L  + +  LR   PF+ F 
Sbjct: 696 SQALYEFIWNQYCDWYLELSKPVLWDENAPVERARGTRRT-LVRVLEVALRLAHPFMPFI 754

Query: 798 AEEAWKFVG--TGKPGESIFTQTY-----SKFDAPDEALLAKWNRIREIRDVVNKDIEAV 850
            EE W+ +    G  G++I  Q +     ++ DA  E  + +W  ++E+       +  +
Sbjct: 755 TEEIWQRIAPLAGIDGKTIMLQPWPVANEARIDAAAEGDI-EW--LKELM----VGLRNI 807

Query: 851 RAEGKVGSSLQANLQL-TAPADD 872
           RAE  +G      L L  A ADD
Sbjct: 808 RAEMNIGPGKPLPLFLKNANADD 830