Pairwise Alignments

Query, 333 a.a., D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Variovorax sp. SCN45

Subject, 317 a.a., 2-hydroxyacid dehydrogenase from Pseudomonas simiae WCS417

 Score =  201 bits (512), Expect = 2e-56
 Identities = 124/324 (38%), Positives = 189/324 (58%), Gaps = 13/324 (4%)

Query: 1   MTMNIAVLDDYFDTLRTLPCFRKLDG-HRVTVWNDHVDDPDLLASRLADADAVVLIRERT 59
           M++ IAV+DD+      +  +  L+   +V   +D+  D   +  RL   + + ++RER+
Sbjct: 1   MSVQIAVIDDWQHVASDVVNWSVLEAVGQVHFLHDYPTDTATMIERLKGFEVICVMRERS 60

Query: 60  ALRAALLERLPRLRLISQRSVY-PHIDIEACTRLGIVVSSDQHPGTPSY--AAAELTWAL 116
               ALL+ LP+L+L+    +    ID+ A   LGI V      GT SY  AA ELTWAL
Sbjct: 61  TFDKALLQGLPKLKLLVTGGMRNAAIDLPAARALGITVC-----GTDSYKHAAPELTWAL 115

Query: 117 LLCAARRLPQQMASLQRGDWQAGVGSTLRGKTLGIYGYGRIGATVAGYAEAFGMKVLVWA 176
           ++ + R L  +  +L+ G WQ G+G  L GKTLG+ G G IG  VA +A+ FGM+V+ W+
Sbjct: 116 IMASTRNLLAEANALRAGHWQVGLGGDLYGKTLGVLGLGSIGQKVAKFAQVFGMRVIAWS 175

Query: 177 RPDSLQRALADGRQPAPDRDTFFGECDAISLHMRLVPDTRGIVRREDLARMKPTAILVNT 236
              + +RA A+       +   F + D +++H+ L   +RG+V  E L  MKP+A LVNT
Sbjct: 176 ENLTPERA-AESGVTWVSKQALFEQADILTVHLVLSDRSRGLVDAEALGWMKPSARLVNT 234

Query: 237 SRAGLVEPGALVQALQAGRPGMAAVDVYETEPLTDPAD-PLISMPNVVCTPHIGYVTREE 295
           +R  +V+  ALV+AL++GR   AA+DVY  EPL  P D P   +PNV+ TPH+GYV+ + 
Sbjct: 235 ARGPIVDESALVRALESGRLAGAALDVYTEEPL--PVDHPFRRLPNVLATPHVGYVSEQN 292

Query: 296 YDLQFSDVFDQITAFAGGHPINVV 319
           Y   ++ + + I A+A G PI V+
Sbjct: 293 YRQFYAQMIEDIQAWANGAPIRVL 316