Pairwise Alignments

Query, 631 a.a., Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) from Sphingobium sp. HT1-2

Subject, 630 a.a., thiamine biosynthesis protein ThiC from Pseudomonas simiae WCS417

 Score =  824 bits (2129), Expect = 0.0
 Identities = 422/630 (66%), Positives = 482/630 (76%), Gaps = 37/630 (5%)

Query: 11  RVTTGAIRG---SKKIHV-GPR---KVAMREIHLEP------GSGEPPVRVYDTSGPYTD 57
           +V +G+++    S+KI+V G R   +V MREI L+       G    PV VYDTSGPYTD
Sbjct: 17  KVDSGSVQPFTRSQKIYVQGTRPDIRVPMREISLDVTPTDFGGEINAPVTVYDTSGPYTD 76

Query: 58  PDAHIDIMAGLQQLRRDWIRERGDVEEYDAREIKPEDNGLKGPDRSGGVQPFPNVVKRPL 117
           P+  ID+  GL  +R  WI  R D E             L   + +     F +V K P 
Sbjct: 77  PNVIIDVRKGLADVRSPWIEVRNDTERLPGLSSHFGQQRLSDAELTA--LRFAHV-KNPR 133

Query: 118 RAKPGANVSQMHYARRGIITPEMEYVAEREN--LGRAR---LAEYVRDGESWGASIPDYV 172
           RAK GANV+QMHYAR+GIIT EMEYVA REN  L  AR   L +    G S+GAS+P  +
Sbjct: 134 RAKAGANVTQMHYARKGIITAEMEYVAIRENMKLEEARATGLLDQQHAGHSFGASVPKII 193

Query: 173 TPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVASEVDKLVW 232
           TPEFVR+E+ARGRAIIP+NINH E EPM IGRNFLVKIN NIGNSA+ S +  EV KL W
Sbjct: 194 TPEFVREEIARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTW 253

Query: 233 SIRWGADTVMDLSTGRNIHDTREWIIRNSPVPIGTVPIYQALEKVGGIAEDLTWDIFRDT 292
            IRWG+DTVMDLSTG++IH+TREWIIRNSPVPIGTVPIYQALEKVGG AEDLTW++FRDT
Sbjct: 254 GIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELFRDT 313

Query: 293 LIEQAEQGVDYFTIHAGVRLAYIPMAAKRVTGIVSRGGSIMAKWCLAHHKESFLYDHFDE 352
           LIEQAEQGVDYFTIHAGV L Y+P+ AKRVTGIVSRGGSIMAKWCLAHHKE+F Y HFDE
Sbjct: 314 LIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFTYTHFDE 373

Query: 353 ITEIMKAYDIAYSLGDGLRPGSIADANDEAQFSELYTLGELTHRAWKQDVQVMIEGPGHV 412
           I EIMKAYD+++SLGDGLRPGSIADAND AQF EL TLGELT  AWK DVQ MIEGPGHV
Sbjct: 374 ICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKTAWKHDVQTMIEGPGHV 433

Query: 413 PMHKIKENMEKQLQVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAQIGWYGTAMLCYVTP 472
           PM  IKENM+KQL+ C EAPFYTLGPLTTDIAPGYDHITSGIGAA IGW+G AMLCYVTP
Sbjct: 434 PMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTP 493

Query: 473 KEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAKVRDDALSRARFEFRWRDQFNLSLD 532
           KEHLGLP++DDVK G++TYK+AAHAADLAKGHP A++RD+ALS+ARFEFRW DQFNL LD
Sbjct: 494 KEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLD 553

Query: 533 PDTAEQYHDQTLPAEGAKSAHFCSMCGPKFCSMKITQEVRDFAAKKNQPADGFLAAGLTG 592
           PDTA  YHD+TLP + AK AHFCSMCGPKFCSMKITQEVR++AA +              
Sbjct: 554 PDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQR------------- 600

Query: 593 AEVAEASKVAALKGMEEMSKLFKETGSELY 622
               EA  V   KG+ E ++ FK+ GS+LY
Sbjct: 601 ---IEAVDVDVAKGLAEQAQRFKQEGSQLY 627