Pairwise Alignments

Query, 1034 a.a., RND efflux system, inner membrane transporter from Sphingobium sp. HT1-2

Subject, 1027 a.a., Multidrug efflux RND transporter from Pseudomonas putida KT2440

 Score =  568 bits (1465), Expect = e-166
 Identities = 342/1015 (33%), Positives = 572/1015 (56%), Gaps = 15/1015 (1%)

Query: 1    MQLSDLSVRRPVFSAVVAVLMCIVGLVGYFSLSVREYPDTDPPIVSVETTYTGAAASVVE 60
            M+ +D+ VRRPV + VV+ L+ ++GL     L +R+YP  +   +++ T Y GA+A +++
Sbjct: 1    MRFTDVFVRRPVLALVVSSLIILMGLFAMGKLPIRQYPLLESSTITISTEYPGASAELMQ 60

Query: 61   TRITQQIEDAVAGVQGIQTITSTSQDGTSNINIEFDPSRDIDSAANDVRDRVGSVTQDLP 120
              +TQ I  AV+ V+GI  ++S+SQ G S I +    +RD   A  +   +V  V   LP
Sbjct: 61   GFVTQPITQAVSSVEGIDYLSSSSQQGRSLITLRMVLNRDSTQALAETMAKVNQVRYRLP 120

Query: 121  EDALAPEIRKVDSDARSILFLAFSRPGWSPIQISDYLDRNIADRFAAIDGVARVTIGGEA 180
            E A  P +     D+ ++ ++ F+    S  ++SDYL R +  +F+ IDGVA+V   G  
Sbjct: 121  EKAYDPVVELSAGDSTAVAYVGFASDSLSIPELSDYLSRVVEPQFSGIDGVAKVQSFGGQ 180

Query: 181  RPSTRIWFNAEKLAAFGLTPADVEAALRTQNVELPAGRFESKDQNQTLRVERPFATPDQF 240
            R + R+W ++E++A  G+T ADV  A+R  N +   G+   +     ++V+      + F
Sbjct: 181  RLAMRLWLDSEQMAGRGVTAADVAQAVRANNYQATPGQVRGQYVLADIQVDTDLTRVEDF 240

Query: 241  AQLVVGRGEDGYQVKLGDVARIEEGAENPYSSFRSNQGTAIGIGIIRQSGANTLEVAQKA 300
             +L++ R +    V+L D+  +E  A    +S   +   A+ +G+      N L + +  
Sbjct: 241  RELII-RNDGTDLVRLRDIGTVELSAAATQTSATMDGKPAVHLGLFPTPSGNPLVIVEGI 299

Query: 301  KALIKELEPTLPKGMKVAIGTDESLFIERAIDNVYDTLIEAALLVILVIFLFLGSVRATI 360
            + L+ +++ TLP G+ VA+  + + FI+ +I  V  TL+EA L+V+LVI+L LGS+R+ +
Sbjct: 300  RQLLPQIQQTLPPGVYVALAYETARFIDASIHEVLRTLVEAMLIVVLVIWLCLGSLRSVL 359

Query: 361  VPAVTVPICLLATCAVMWLLGLSINLLTLLAFVLAIGLVVDDAIVVLENVYHRVEQGDDP 420
            +  V +P+ +L    +M + G S+NLLTLLA VLAIGLVVDDAIVV+ENV+  +E+G  P
Sbjct: 360  IAVVAIPLSMLGAAGLMLMFGFSLNLLTLLAMVLAIGLVVDDAIVVVENVHRHIEEGKSP 419

Query: 421  LVAAYLGTRQVGFAIISTTLVVCAVFVPVMFLAGQTGLLFRELAIAMIAAIGFSGFISLS 480
            + AA  G R++   +I+ TL + AV+ P+  + G TG LFRE A+ +  A+  SG ++L+
Sbjct: 420  IAAALAGAREIAGPVIAMTLTLAAVYAPIGLMGGLTGTLFREFALTLAGAVIVSGIVALT 479

Query: 481  LAPMLCSKLLK-NAERGRLARWVDDRFQRIEHGYGRWLDWTLKKPLMPLLGVAIFLGVAF 539
            L+P++ S LL+   + G +A   D  F  +   YGR L +TL    +   GVA+ + ++ 
Sbjct: 480  LSPVMSSLLLQPGQQHGAMAAIADRLFGTLSGVYGRVLAYTLAHRWIS-GGVALLVCLSL 538

Query: 540  -FLFTRLPAELAPAEDTGVVEANVNAPEGTGFDRMMAYMQKIENDLAFLRKDGTLQNLVI 598
             +L+     ELAP ED   V   + +P+    +    +  K++  +  + +  T    +I
Sbjct: 539  PWLYLLPQRELAPPEDQAAVLTAIKSPQHASLEYAERFALKLDQVMKSIAE--TTDTWII 596

Query: 599  RTPGGFGTTDDYNNGNVIAFLRPWEDRTITTAEVATIINKVIADQPGVRGNAAPRSGL-G 657
               G  G    +   N+ A    W+ R  + A+V   + + +AD  G    A   + L G
Sbjct: 597  N--GTDGPAASFGGINLSA----WQARERSAAQVQAQLQQAVADIEGSSIFAFQVASLPG 650

Query: 658  RGRGLPVNIVL-AGSTYEGLVAARDRIMLAAASYPGLINLDSDYKETKPQMRIETDLQRA 716
               GLPV +VL +   Y  L    + +   A        +DSD     P +++  D  +A
Sbjct: 651  SSGGLPVQMVLRSAQDYPELFQTMEVLKQRARDSGLFAVVDSDLDYNNPVVKVRVDRAKA 710

Query: 717  GDLGVSVNDVSQALQSLLGSRRVTTYVDRGEEYRVLVQAERDGRQTLADLERIQVRSRRG 776
              LG+S+  + ++L  L+G + +  +   G  Y V+ Q+ +D R T A L R  VR+  G
Sbjct: 711  ASLGISMQAIGESLGVLVGEQYLNRFALFGRSYDVIPQSIQDQRLTPAALSRQYVRAEDG 770

Query: 777  VLVPLSAVVTVREVAGPRQLNRYNKLRAITLTAALAPGTSLGQGLAFLEDQARQSPEVLA 836
             LVPL+ +V +     P +L ++++  A TL A  APG S+G  +AFLE    + P   +
Sbjct: 771  SLVPLATLVRLDIEVAPNRLLQFDQQNASTLQAIPAPGVSMGNAVAFLEQLTAELPPGFS 830

Query: 837  IGYRGESQSLRETGGSIWIVFGLTILIVYLLLAAQFESFIHPGVIIATVPLAVAGGALGL 896
              ++ ES+   + G ++   F   ++++YL+LAAQ+ES + P +I+ TVPL++ G  L L
Sbjct: 831  HDWQSESRQYVQEGFALMWAFLAALVVIYLVLAAQYESLVDPLIILVTVPLSICGALLPL 890

Query: 897  AITGGSINLYSQIGIVMLVGLAAKNGILIVEFANQLR-DEGMEIAEAIREAAKRRLRPIL 955
            A+   ++N+Y+QIG+V L+GL +K+GIL+V FAN+++  + ++ A AI  AA+ RLRP+L
Sbjct: 891  ALGWATLNIYTQIGLVTLIGLISKHGILMVAFANEIQVRDNLDRAAAIVRAAQIRLRPVL 950

Query: 956  MTSIATVIGAVPLVLRGGAGAAARHSIGVVIVFGVSLATLITLFLIPIFYSRVAK 1010
            MT+ A   G +PL+   GAGA +R  +GVVIV G+ + TL TLF++P  Y+ +A+
Sbjct: 951  MTTAAMTFGVLPLLFASGAGANSRFGLGVVIVCGMLVGTLFTLFVLPTIYAWLAR 1005