Pairwise Alignments
Query, 4317 a.a., non-ribosomal peptide synthase (subunit of ferribactin synthase) from Pseudomonas putida KT2440
Subject, 3354 a.a., non-ribosomal peptide synthetase from Pseudomonas fluorescens SBW25
Score = 1414 bits (3660), Expect = 0.0
Identities = 1011/2651 (38%), Positives = 1381/2651 (52%), Gaps = 174/2651 (6%)
Query: 1721 LSYSQQRMWFLWQMEPDSPAYNVGGMARLRGTLHVDAFERALQALIVRHETLRTTF--PS 1778
LS +Q + F +EPDS Y + G L + AF A QAL+ RH LR+ F
Sbjct: 10 LSPTQHGLLFHSVVEPDSRVYYQQLSLEMNGPLQLPAFRAAWQALMQRHAVLRSAFLWED 69
Query: 1779 IDGVPYQCVAEDSGLHLDWQDFSALSDDACQQRLQQLADDQAHQPFDLERGPLLRACLVK 1838
+D YQ V D GL L D+ +D + LQQLA +Q QP +L PL+R LV+
Sbjct: 70 LDDA-YQVVQTDVGLPLSELDWQGHADP--KTALQQLALEQRAQPLELNDSPLMRLTLVR 126
Query: 1839 ANEREHFFVLTLHHIVTEGWAMDIFARELGELYEAFVDDRESPLAPLPVQYLDYSVWQRQ 1898
+ + T HHI+ +GW++ I +E LY R + LAP Y DY W
Sbjct: 127 LEPQRWHLIWTFHHIIMDGWSVGIAIQEWLALYYEHAHGRPANLAPTRA-YRDYIAW--- 182
Query: 1899 WLESGEGARQLAYWKHRLGDEHPVLALPADRPR--PAVQSHRGELYRFELDPALVARVHA 1956
L + A ++W+++L D LP R P + E L ++
Sbjct: 183 -LAEQDMAATESFWRNQLQDVSEPTPLPDFGLRLVPPTDAPCAEREN-RLSADETEQLAQ 240
Query: 1957 FNSQRGLTLFMTMTATLAALLHRYSGQRDLRIGAPVANRIRPES----EGLIGAFLNTQV 2012
F + LTL + A LL +++G+ D+ G VA R PE+ + +G F+NT
Sbjct: 241 FARRHHLTLNTLIQGAWALLLGQHAGRDDVIYGVTVAGR--PENLAAVDSTVGLFINTLP 298
Query: 2013 LRCELDGQMTASALLEQVRQAAIEGQSHQDLPFDQLVEALQPPRSSAYNPLFQVMCNVQR 2072
LR + L+Q++ A + + H LP +L + +A LF + +
Sbjct: 299 LRVQWADGPALVDWLQQLQHANSDLRHHAYLPLGKLKSM---SKIAAEQALFDSILVFEN 355
Query: 2073 WAFQQS--RTLAGMQ---------VDYLVNDASATKFDLYLEVTDLDGRLGCCLTYSRDL 2121
+ + + G+ D LV F L L V + +L +Y+R
Sbjct: 356 FPVTDALNQDAGGLSFADPNREQATDGLVLTQGRNHFPLSLIVVPGE-QLHYLFSYNRSR 414
Query: 2122 FDAPRIARMAEHWQQLLVGLLDNPQHRLCELPMLSSAEQQVLTGQLQGEHDFDLGQTLHG 2181
F I ++ + +L+ + PQ R+ EL + + E+Q L G LH
Sbjct: 415 FSDAEITLLSAQLRNVLLAMAAQPQCRVGELDWMGADERQQLQALGCGTPLAVPEACLHQ 474
Query: 2182 LFAAQAARTPQAGALTFAGQHLTYAELDQQANRLARALRERGVGPQVRVGLALERSLEMV 2241
F Q A P A+ L+YAELDQ+ANRL+ LR G+G V LALERS + V
Sbjct: 475 RFEQQVAAAPDQPAILDREGVLSYAELDQRANRLSHHLRAEGIGHHSLVALALERSADFV 534
Query: 2242 VGLLAILKADGAYVPLDPEYPLDRLRYMIEDSRIGLLLSQRALLHTLGELPEGVASWSLE 2301
+ LLA LKA AY+PLD + P RL +++DSR LL+ A L L E SL
Sbjct: 535 IALLATLKAGAAYLPLDLKQPAGRLADVLQDSRAALLIGATAS-PLLARLAEHTPLLSLA 593
Query: 2302 DDAASLAAYSDAPLDNLSLPQHQAYLIYTSGSTGKPKGVVVSHGEFAMHCQAV------- 2354
+ A ++AA AY+IYTSGSTG PKGVVV H + AV
Sbjct: 594 EQAEAIAAQPGTSPAVAHSLDDAAYVIYTSGSTGTPKGVVVEHRAIVDYLTAVHSVLKPP 653
Query: 2355 -IAAFGMRSDDCELHFYSINFDAASERLWVPLLCGARVVL-RAQGQWGAEDICQLVREQQ 2412
A +G+ S SI D +L+ L G ++L + + + +L +
Sbjct: 654 AAARYGLLS--------SIAADLGHTQLFGALCSGGSLLLVDDESGFSPLALAELFSQHP 705
Query: 2413 VSILGFTPSYGSQLAQYLGGRGEQLPVRLVITGGEALTGEHLQRIRQAFAPQQCFNAYGP 2472
V +L TPS+ S L Q L LP L++ GG+AL+ L ++ + FN YGP
Sbjct: 706 VDVLKITPSHLSGLLQALPD-ARLLPRSLLVFGGDALSPALLAQVNGLAPGLRVFNHYGP 764
Query: 2473 TETVVMPLACLAPEALPADLGSVPIGRVIGSRTAYILDEDLALLPQGGIGELYVGGAGLA 2532
+E V +A E P S+ +GR + +R ++D + G GEL + GA LA
Sbjct: 765 SEATV---GAIATELTPGQR-SIALGRPLPNRQLRVVDAQGREVATGVSGELLISGA-LA 819
Query: 2533 QGYHDRPGLTAERFVADPFSAEGGRLYRTGDLVRLGTDGLVEYVGRADQQVKIRGFRIEL 2592
+GY R L+AERF+ D + R YRTGD VR DG + ++GR D QVKIRG R+EL
Sbjct: 820 RGYLHRDDLSAERFLRDE---QQNRWYRTGDRVRWLVDGQLAFLGRVDSQVKIRGNRLEL 876
Query: 2593 GEIESRLLAHED-VDEAVVLALDLPGGKQLVGYLVCRQATAGNDVQQLLREAVKADARQH 2651
GE+E+++ +++ VV AL+L G +LV YLV Q+ + ++ D
Sbjct: 877 GEVEAQIKRLSPLIEQVVVRALELDGSLRLVAYLVASQSLSALKLRN--------DLGNR 928
Query: 2652 LPDYMVPAHLVLLDSLPLMGNGKLDRHALPLPDLE-QARQQYQAPGNEVEAQLAQIWRDV 2710
+PDYMVPAH + LD LPL NGK+D LPLP + AP NEVE LA IW+DV
Sbjct: 929 VPDYMVPAHFITLDELPLTRNGKVDAQRLPLPPTTGDDSATHVAPRNEVETLLAAIWQDV 988
Query: 2711 LNVARVGVQDNFFELGGDSILSIQVVSRARQAGLQFTPRDLFQHQTIQTLATVVQLSEAA 2770
L +VGV DNFF +GGDSIL++Q+++RA Q GL+ TPR LF+++TI +A V+ ++A+
Sbjct: 989 LKREQVGVHDNFFAIGGDSILNLQIIARANQQGLKLTPRQLFENRTIADIARVLG-ADAS 1047
Query: 2771 STVEQGLRQGQA-GLTPIQHWFFDSDVPQPQHWNQTVLLEVRQPLVEATLEQALAALVQH 2829
V + L G A L+ Q + P W L QPL L QAL AL QH
Sbjct: 1048 HAVAEQLADGYALPLSAGQRARLEQG-PLTATWRCVALA---QPLDRDLLSQALGALQQH 1103
Query: 2830 HDSLRLRFSDAQGRWQAQYVQPGAEQLLWSATVADFNDCQ--ALYTDVQRSLDLQQGPLL 2887
H +LRL F DA G+ Q V P A + T D++ Q AL +LDL+ G L
Sbjct: 1104 HQALRLAF-DADGQ-QRVLVAPKAAAI----TSGDYHPAQLHALAQAGVDTLDLRAGQSL 1157
Query: 2888 RALLVRDGQGTQRLLLAIHHLVVDGVSWRVLLEDLQA------LYRGQPLPAKTHAVGDW 2941
A L+ + LLLA H L VD SW +LL DL L R LP W
Sbjct: 1158 HASLLGE-----HLLLAAHPLCVDESSWSLLLTDLNLALAQLRLQRPVRLPYTGGNFTQW 1212
Query: 2942 AARLASYAGSDSLRDELAWWQGQLGGVRRELPCDHPQGSNLHRHAQTLAIGLDVEQTRQL 3001
++A SD+L + W G +LP H Q S++ + + A ++++ +
Sbjct: 1213 TRHQQAHAESDALDEAWEHWLQYAGLDTLQLPDSH-QPSSVVEQSVSAATSSELKRLTDV 1271
Query: 3002 LQLAPAAYHTQVNDLLLTALARALCRWSGDEEVLVQLEGH---------GRDGLFEDMDL 3052
L H N LL T +A GD + + L + D++
Sbjct: 1272 L-------HLDWNSLLATVVAEQC----GDGLLALDLYAARPATERLPVAAPLVLADLEP 1320
Query: 3053 TRSVGWFTNAYPLSLRPLPGEDDAARAGSIKRIKE---QLRHVPHKGLGYGVLRYLADAA 3109
VG A P+ L+ AA A +++R++ QLR P G+ YG LRYL+D
Sbjct: 1321 ALIVGALDLAVPVFLQ-------AAGATALQRLQSVAAQLRAYPQHGVDYGALRYLSDNT 1373
Query: 3110 G-REQMAALPQARITFNYLGQFDQQFDSAALFQPLEASAGLAHDLDAPLPNWLSVDGQVY 3168
++ + LP A I ++ G FD + L + A+ + + L +D
Sbjct: 1374 YLQDPLRDLPAAPIAVHWRGDFDSHREQRGLLAQITAA-----NTPGASSHALRIDAHWQ 1428
Query: 3169 GGALQLRWTFSAERYDQQTIARLAEGYRQELLALVAHCLADGNGSFTPSDFPLAHLTQEQ 3228
L LR + A A + L AL A LA+ + FPL H
Sbjct: 1429 DDQLHLR-------VEGALAADWAPQLAERLSALAA-LLAEPDLRPASEAFPLCHKQATT 1480
Query: 3229 IDALPVPAAQIEDVYPLTPMQEGMLLHTLLEPGTGLYYMQDRYRINSALDPERFAQAWQA 3288
+ P+ +EDVYPL+ MQ+GMLLHTLL+P +G+Y MQ RY + L AW+
Sbjct: 1481 LAGEPLDWPNLEDVYPLSSMQQGMLLHTLLQPHSGIYLMQQRYSWDGVLQRTAMETAWRL 1540
Query: 3289 VVARHEALRASFSWNSGEAMLQIIHKPGNLAVDYQDWRGLADDAQEQRLQALHKQEREAG 3348
+ RH +R +F W LQ +++ A D+QD R L D Q Q + + +R G
Sbjct: 1541 FLDRHPMMRTAFWWQDDHEPLQCVYRKTAPAFDWQDVRHLDDAQQRQAMDQALEAQRVQG 1600
Query: 3349 FALLSEAPFHLRLVRVAEERYWFMMSNHHILIDAWCRSLLMNDFFEVYQALGEGRQAQLP 3408
F + S HLR+ ++ E+R+ + S HHIL DAWC LLM D +YQA+ P
Sbjct: 1601 FDMSSAPLTHLRVFQLDEQRFAVVRSFHHILTDAWCFGLLMEDLLAIYQAVVRQEPVARP 1660
Query: 3409 VPPRYRDYIGWLQRQGLDDARAWWQANLAGFERATAIPSDRPLRHDHAGSGMVVGDCYTR 3468
+R Y+ WL+RQ + A A+WQA+LAGF T + D L VGD
Sbjct: 1661 RLRSFRGYMSWLERQDMAAAHAFWQADLAGFSEPTPLHVDGALARPEQAPEQ-VGDVDQT 1719
Query: 3469 LEMNDGVRLRELAQAHQLTVNTFAQAAWALVLSRYSGDRDVAFGVTVAGRPVSMPQMQRT 3528
L ++ RL++L Q +QLT NT+ Q AWAL+LSRYSG+RDV FGVTVAGRP + ++
Sbjct: 1720 LSISQTQRLQQLCQQYQLTPNTWIQGAWALLLSRYSGNRDVLFGVTVAGRPTDLAGVEEM 1779
Query: 3529 VGLFINSVALRVQLPAASERCSVRQWLQGLLQSNMELREYEYLPLVAIQACSELPKGQPL 3588
VGLFINS+ LR+ + V WLQ LL N LRE+E LV IQ S +P+GQPL
Sbjct: 1780 VGLFINSLPLRIDV---DPEAPVGAWLQALLSHNARLREHESASLVDIQRSSNVPRGQPL 1836
Query: 3589 FDSLFVFENAPVE-TAVLNHAQHLNASSDSGRTHTNFPLTAVCYPGDDLGLHLSFDQRYF 3647
FDSL VFENAP++ ++V A ++ D R HTNFP+T V YPGD LG+ LS+D + F
Sbjct: 1837 FDSLVVFENAPLDISSVQLDAFSIDIYED--RVHTNFPMTVVLYPGDRLGIRLSYDSQRF 1894
Query: 3648 DYPTVERLLAEFKRLLLALVQGFEGEVSELPLLSAQEQGFLLEDCNRTERVYPLEQSYIA 3707
TV+R+L +LL +++ E + L +LSA E+ L + NR+E +PL+Q Y A
Sbjct: 1895 STDTVQRMLGHLVQLLSSMLDAPEAPLGTLHMLSASEREQLQVEWNRSEVDFPLDQGYAA 1954
Query: 3708 QFEAQVVAHPQRTVARCLEASYDYAGLNLAANRLGHALVAAGVCVDQPVALLAERGLPLL 3767
F QV PQ+ A L S YA L+ AN + HAL AAG + VAL AERGL LL
Sbjct: 1955 LFAEQVRRRPQQIAAVHLHESLTYAELDRRANAVAHALQAAGAGPETLVALFAERGLALL 2014
Query: 3768 GMIVGSFKAGAGYLPLDPGLPAARLQSIIQLSRTP-VLVCSAACAEQGRQLLGELEASLR 3826
+++G+ KAGA + LD PA RL ++ L P VLVC A A L G L L+
Sbjct: 2015 TLMIGTLKAGAAFQALDIQQPATRLAELLSLGEAPLVLVCDKATA----VLDGVLPQLLK 2070
Query: 3827 -PQLLVWEDVQANPIASHNPGIHSGPDNLAYVIYTSGSTGLPKGVMVEQRGMLNNQLSKV 3885
P+ LV + + + +H PD LAYVI+TSGSTG PKGVMVEQRGMLNN KV
Sbjct: 2071 QPRCLVAQTLWQGEVKPSVDYVHI-PDQLAYVIFTSGSTGTPKGVMVEQRGMLNNIFGKV 2129
Query: 3886 PYLALSEQDVIAQTASQSFDISVWQFLAAPLFGAKVEIVPNVIAHDPQGLLAHVQATGIT 3945
P L L E D +AQTAS +FDI VWQFLAAPL GA V I+P+ AHDP LL VQA +T
Sbjct: 2130 PALGLGEHDRLAQTASPAFDICVWQFLAAPLVGACVHILPDAQAHDPLALLDAVQAQQLT 2189
Query: 3946 VLESVPSLIQGML----ASDHQALDGLRWMLPTGEVMPPELAAQWLQRYPQIGLVNAYGP 4001
+LE+VP+LI+GML A DH L LRW+LPTGE +PP LA W R+P I L+NAYGP
Sbjct: 2190 LLETVPALIRGMLQEVRAQDH--LASLRWLLPTGEALPPTLAQDWFARFPSIPLMNAYGP 2247
Query: 4002 AECSDDVAFFRV-DAASTQGSYLPIGTPTDNNRLYLFGEDQALVPLGAVGELCVAGAGVG 4060
AECSDDVAF+ + +A S ++PIG PT NN++++ D VP+G GELC+ G GVG
Sbjct: 2248 AECSDDVAFYPITEAPSDDCLHMPIGRPTANNQVFVLDADLRCVPIGVPGELCIGGVGVG 2307
Query: 4061 RGYVGDPVRTALAFIPHPYGAPGERLYRTGDLARQRLDGVLEYVGRIDHQVKIRGYRIEL 4120
RGY+GDP RT AF+ HP+ G RLYR+GD+ R R DGV+EY+GR D QVKIRGYRIEL
Sbjct: 2308 RGYLGDPQRTREAFVAHPF-QTGARLYRSGDIGRLRADGVIEYLGRRDQQVKIRGYRIEL 2366
Query: 4121 GEIEARLHEQAEIRDAAVAVQEGVNGKHLVGYLVAHQGVSADAALLEQVKQR-----LRA 4175
GEIE RL + + AAV G LVA + A A L Q Q L
Sbjct: 2367 GEIENRLMQHPAVDSAAVLALPDARG---ALQLVAWYVLDAAAELGGQTAQSLLTAYLER 2423
Query: 4176 ELPEYMVPLHWGWFDSLPHNANGKLDRKALPAIDI--GGQYSQAYLAPRNELEDVLAGIW 4233
+L YMVP W LP NANGK+DR+AL A+D+ +APR E VLA +W
Sbjct: 2424 QLASYMVPARWLALAQLPLNANGKVDRRALAALDVQQAEPAQGVVVAPRTPTEKVLAELW 2483
Query: 4234 ADVLKAERVGVHDNFFELGGHSLLATQIASRVQKQLQLNVPLRAMFECSTVEALAEYVQG 4293
D+L VGVHD+FF +GGHSLLATQ+ SR++++L +++PLR +FE T+ LA+ V
Sbjct: 2484 QDLLGVAGVGVHDDFFAIGGHSLLATQMLSRIRRRLNVSLPLRTLFEGGTLAQLAQAVD- 2542
Query: 4294 LQGSALDDDKV 4304
Q DD ++
Sbjct: 2543 QQAQVSDDSEI 2553
Score = 714 bits (1842), Expect = 0.0
Identities = 528/1597 (33%), Positives = 772/1597 (48%), Gaps = 93/1597 (5%)
Query: 597 LKVEAVAADDHFLLLGGNSIAATQATARLADELGIDLSLRTLFEAPVLADYSKAVAQIIA 656
L+++A DD L ++AA A +LA+ L +L L P L S+A +
Sbjct: 1421 LRIDAHWQDDQLHLRVEGALAADWAP-QLAERLS---ALAALLAEPDLRPASEAFP--LC 1474
Query: 657 DGAAATTAITTLE---RAQALPQSLAQNRLWLLWQLEPQSAAYNIPAGLHLRGELDVNAL 713
A T A L+ P S Q + L L+P S Y + G L A+
Sbjct: 1475 HKQATTLAGEPLDWPNLEDVYPLSSMQQGMLLHTLLQPHSGIYLMQQRYSWDGVLQRTAM 1534
Query: 714 HVAFQALVARHESLRTVFS-EENGQALQRILPQQPLSLHRLDLE--GHSPEQVAAQRETE 770
A++ + RH +RT F +++ + LQ + + + D+ + ++ A + E
Sbjct: 1535 ETAWRLFLDRHPMMRTAFWWQDDHEPLQCVYRKTAPAFDWQDVRHLDDAQQRQAMDQALE 1594
Query: 771 AR--QPFDLTQGPLLRVTLVRLGDEEHQLWVTLHHIVADGWSLNILLEEFAKLYAARCQG 828
A+ Q FD++ PL + + +L ++ + + HHI+ D W +L+E+ +Y A +
Sbjct: 1595 AQRVQGFDMSSAPLTHLRVFQLDEQRFAVVRSFHHILTDAWCFGLLMEDLLAIYQAVVRQ 1654
Query: 829 LEANLAPLPLGYADYGSW-QRQWLADGEAERQLQYWKAHLGGELPALDLCTDHP--RASQ 885
E P + Y SW +RQ +A A +W+A L G L D R Q
Sbjct: 1655 -EPVARPRLRSFRGYMSWLERQDMAAAHA-----FWQADLAGFSEPTPLHVDGALARPEQ 1708
Query: 886 REHSAARFSLKVPVRLGEALKGLAHQQQASLFMVLLAGWQALLQRYSGQADIRVGVPNAN 945
+ + + L+ L Q Q + + W LL RYSG D+ GV A
Sbjct: 1709 APEQVGDVDQTLSISQTQRLQQLCQQYQLTPNTWIQGAWALLLSRYSGNRDVLFGVTVAG 1768
Query: 946 RPR--LETQGMVGFFINTQVLRARFDGRHSFTQLLTQVRQATLQAQANQDLPFEQLVEAL 1003
RP + MVG FIN+ LR D L + + + ++ + +
Sbjct: 1769 RPTDLAGVEEMVGLFINSLPLRIDVDPEAPVGAWLQALLSHNARLREHESASLVDIQRSS 1828
Query: 1004 PDAREQGLFQ--VMFNHQQRDLSALRRLPGLLAEELAWHSREAKFDLQLHSEEDHLG--- 1058
R Q LF V+F + D+S+++ F + ++ + H
Sbjct: 1829 NVPRGQPLFDSLVVFENAPLDISSVQL---------------DAFSIDIYEDRVHTNFPM 1873
Query: 1059 --------RLSLAFDYAAELFEASTVERLAHHLLALLEQVCAAPQQALGDVQLLDEPGRA 1110
RL + Y ++ F TV+R+ HL+ LL + AP+ LG + +L R
Sbjct: 1874 TVVLYPGDRLGIRLSYDSQRFSTDTVQRMLGHLVQLLSSMLDAPEAPLGTLHMLSASERE 1933
Query: 1111 QL-LGWGQAPAA-AAQHLLVEQLNEQVRLTPQRTALVWDGGSLDYAGLHQQANRLAHYLR 1168
QL + W ++ EQVR PQ+ A V SL YA L ++AN +AH L+
Sbjct: 1934 QLQVEWNRSEVDFPLDQGYAALFAEQVRRRPQQIAAVHLHESLTYAELDRRANAVAHALQ 1993
Query: 1169 DKGVGPDTCVAIAIERSPQLLVGLLAILKAGGAYVPLDVDYPAERLAYMLADCDARLLL- 1227
G GP+T VA+ ER LL ++ LKAG A+ LD+ PA RLA +L+ +A L+L
Sbjct: 1994 AAGAGPETLVALFAERGLALLTLMIGTLKAGAAFQALDIQQPATRLAELLSLGEAPLVLV 2053
Query: 1228 ---SHSSLLGKLPQV-DGVSAIALDQLHLDSWPSHAPGLHLHGDNLAYVIYTSGSTGQPK 1283
+ + L G LPQ+ + L +H+ D LAYVI+TSGSTG PK
Sbjct: 2054 CDKATAVLDGVLPQLLKQPRCLVAQTLWQGEVKPSVDYVHIP-DQLAYVIFTSGSTGTPK 2112
Query: 1284 GVGNTHAALAERLQWMQTTYALNDSDVLMQKAPISFDVSVWECFW-PLVTGCKLVLAGPG 1342
GV + + L + D L Q A +FD+ VW+ PLV C +L
Sbjct: 2113 GVMVEQRGMLNNIFGKVPALGLGEHDRLAQTASPAFDICVWQFLAAPLVGACVHILPDAQ 2172
Query: 1343 EHRDPQRIAALVQAYGVTTLHFVPPLLQVFVQEPQASA-CSSLRWVFSGGEALSATLRDR 1401
H DP + VQA +T L VP L++ +QE +A +SLRW+ GEAL TL
Sbjct: 2173 AH-DPLALLDAVQAQQLTLLETVPALIRGMLQEVRAQDHLASLRWLLPTGEALPPTLAQD 2231
Query: 1402 VLQVLPQVQLHNRYGPTETAINVTHWHCQVVDGE---RSPIGRPLGNVLCRVLDDELELS 1458
P + L N YGP E + +V + + PIGRP N VLD +L
Sbjct: 2232 WFARFPSIPLMNAYGPAECSDDVAFYPITEAPSDDCLHMPIGRPTANNQVFVLDADLRCV 2291
Query: 1459 APGVPGELYLGGAGLARGYLGRPGLTAERFVPQADGNGQRLYRSGDRARWQVQLEALEYL 1518
GVPGEL +GG G+ RGYLG P T E FV G RLYRSGD R + +EYL
Sbjct: 2292 PIGVPGELCIGGVGVGRGYLGDPQRTREAFVAHPFQTGARLYRSGDIGRLRAD-GVIEYL 2350
Query: 1519 GRLDQQVKVRGFRVEPEEVQACLLAQAGVEQALVLIHKDAIGA-QLVGYY--------SG 1569
GR DQQVK+RG+R+E E++ L+ V+ A VL DA GA QLV +Y G
Sbjct: 2351 GRRDQQVKIRGYRIELGEIENRLMQHPAVDSAAVLALPDARGALQLVAWYVLDAAAELGG 2410
Query: 1570 SAQPAEVLAVLAEQLPAYMVPAQLIPLAQMPLGPSGKVDRKALPAPVWQQREH-----VE 1624
+ + A L QL +YMVPA+ + LAQ+PL +GKVDR+AL A QQ E V
Sbjct: 2411 QTAQSLLTAYLERQLASYMVPARWLALAQLPLNANGKVDRRALAALDVQQAEPAQGVVVA 2470
Query: 1625 PRTELQQQVAAIWRDVLNLPRIGLQDDFFALGGHSLLATQIVSRTRQACDVELPLKALFE 1684
PRT ++ +A +W+D+L + +G+ DDFFA+GGHSLLATQ++SR R+ +V LPL+ LFE
Sbjct: 2471 PRTPTEKVLAELWQDLLGVAGVGVHDDFFAIGGHSLLATQMLSRIRRRLNVSLPLRTLFE 2530
Query: 1685 ASELGAFCAEIARLRAAGERNLQGAITRVDRRQAVPLSYSQQRMWFLWQMEPDSPAYNVG 1744
L + + + I V R Q + LSY+QQR+WFL + E + AYN+
Sbjct: 2531 GGTLAQLAQAVDQQAQVSD---DSEIVPVPRNQTLALSYAQQRLWFLDRFEGPNAAYNMS 2587
Query: 1745 GMARLRGTLHVDAFERALQALIVRHETLRTTFPSIDGVPYQCVAEDSGLHLDWQDFSALS 1804
+ RLRG L + A ++ALQ ++ RHE LRTTF P Q + E L L + +
Sbjct: 2588 SVVRLRGALDIAALQQALQRVLERHEALRTTFHLKGEQPCQVINEAPTLDLTPVNVES-- 2645
Query: 1805 DDACQQRLQQLADDQAHQPFDLERGPLLRACLVKANEREHFFVLTLHHIVTEGWAMDIFA 1864
LQ + D Q+ QPFDL++ P+LRA L+ +H L LHHI T+ W+M I
Sbjct: 2646 -----HALQSVIDRQSAQPFDLQQAPMLRAHLLHLGTDDHVLQLVLHHIATDAWSMGILI 2700
Query: 1865 RELGELYEAFVDDRESPLAPLPVQYLDYSVWQRQWLESGEGARQLAYWKHRLGDEHPVLA 1924
+EL Y+A+ L LP+QY DY+ WQR + + AR + YW+ +L ++A
Sbjct: 2701 QELITGYQAYASGVNPTLPALPIQYADYAQWQRSEPQQRQLARAIDYWRRQLDGAPTLIA 2760
Query: 1925 LPADRPRPAVQSHRGELYRFELDPALVARVHAFNSQRGLTLFMTMTATLAALLHRYSGQR 1984
LP D PRP ++G + PA + A+ Q TLFM + +LL R +G
Sbjct: 2761 LPLDAPRPTQPDYQGAALTQQFSPAHTQVLKAYAQQHKATLFMVLLNAFNSLLQRATGAN 2820
Query: 1985 DLRIGAPVANRIRPESEGLIGAFLNTQVLRCELDGQMTASALLEQVRQAAIEGQSHQDLP 2044
D +G +ANR E LIG F+N +R LD T L+++R+ + HQ +P
Sbjct: 2821 DFIVGTDLANREHSALEPLIGFFVNVLPIRARLDDSDTFDHRLQRLREDCLAAFQHQQVP 2880
Query: 2045 FDQLVEALQPPRSSAYNPLFQVMCNVQRWAFQQSRTLAGMQVDYLVNDASATKFDLYLEV 2104
FD+LVE LQPPR+ NPL QV+ +Q Q + +L+G+ V++L +KFDL + V
Sbjct: 2881 FDKLVETLQPPRTPGVNPLVQVLFVMQNTP-QGTASLSGLAVEHLAPQQETSKFDLAVFV 2939
Query: 2105 TDLDGRLGCCLTYSRDLFDAPRIARMAEHWQQLLVGL 2141
+ + L Y + A +A + +Q LL L
Sbjct: 2940 EEDENGLTVRWVYRTSVLSAQTVADLEHGFQALLDNL 2976
Score = 525 bits (1353), Expect = e-152
Identities = 375/1089 (34%), Positives = 551/1089 (50%), Gaps = 58/1089 (5%)
Query: 3239 IEDVYPLTPMQEGMLLHTLLEPGTGLYYMQDRYRINSALDPERFAQAWQAVVARHEALRA 3298
IED+Y L+P Q G+L H+++EP + +YY Q +N L F AWQA++ RH LR+
Sbjct: 4 IEDIYSLSPTQHGLLFHSVVEPDSRVYYQQLSLEMNGPLQLPAFRAAWQALMQRHAVLRS 63
Query: 3299 SFSWNSGEAMLQIIHKPGNLAVDYQDWRGLADDAQEQRLQALHKQEREAGFALLSEAPFH 3358
+F W + Q++ L + DW+G AD + LQ L ++R L
Sbjct: 64 AFLWEDLDDAYQVVQTDVGLPLSELDWQGHAD--PKTALQQLALEQRAQPLELNDSPLMR 121
Query: 3359 LRLVRVAEERYWFMMSNHHILIDAWCRSLLMNDFFEVYQALGEGRQAQLPVPPRYRDYIG 3418
L LVR+ +R+ + + HHI++D W + + ++ +Y GR A L YRDYI
Sbjct: 122 LTLVRLEPQRWHLIWTFHHIIMDGWSVGIAIQEWLALYYEHAHGRPANLAPTRAYRDYIA 181
Query: 3419 WLQRQGLDDARAWWQANLAGFERATAIPSDRPLRHDHAGSGMVVGDCYTRLEMNDGVRLR 3478
WL Q + ++W+ L T +P D LR + + RL ++ +L
Sbjct: 182 WLAEQDMAATESFWRNQLQDVSEPTPLP-DFGLRL-VPPTDAPCAERENRLSADETEQLA 239
Query: 3479 ELAQAHQLTVNTFAQAAWALVLSRYSGDRDVAFGVTVAGRPVSMPQMQRTVGLFINSVAL 3538
+ A+ H LT+NT Q AWAL+L +++G DV +GVTVAGRP ++ + TVGLFIN++ L
Sbjct: 240 QFARRHHLTLNTLIQGAWALLLGQHAGRDDVIYGVTVAGRPENLAAVDSTVGLFINTLPL 299
Query: 3539 RVQLPAASERCSVRQWLQGLLQSNMELREYEYLPLVAIQACSELPKGQPLFDSLFVFENA 3598
RVQ ++ ++ WLQ L +N +LR + YLPL +++ S++ Q LFDS+ VFEN
Sbjct: 300 RVQW---ADGPALVDWLQQLQHANSDLRHHAYLPLGKLKSMSKIAAEQALFDSILVFENF 356
Query: 3599 PVETAVLNHAQHLNASSDS------------GRTHTNFPLTAVCYPGDDLGLHLSFDQRY 3646
PV A+ A L+ + + GR H FPL+ + PG+ L S+++
Sbjct: 357 PVTDALNQDAGGLSFADPNREQATDGLVLTQGRNH--FPLSLIVVPGEQLHYLFSYNRSR 414
Query: 3647 FDYPTVERLLAEFKRLLLALVQGFEGEVSELPLLSAQEQGFLLEDCNRTERVYPLEQSYI 3706
F + L A+ + +LLA+ + V EL + A E+ L T P E
Sbjct: 415 FSDAEITLLSAQLRNVLLAMAAQPQCRVGELDWMGADERQQLQALGCGTPLAVP-EACLH 473
Query: 3707 AQFEAQVVAHPQRTVARCLEASYDYAGLNLAANRLGHALVAAGVCVDQPVALLAERGLPL 3766
+FE QV A P + E YA L+ ANRL H L A G+ VAL ER
Sbjct: 474 QRFEQQVAAAPDQPAILDREGVLSYAELDQRANRLSHHLRAEGIGHHSLVALALERSADF 533
Query: 3767 LGMIVGSFKAGAGYLPLDPGLPAARLQSIIQLSRTPVLVCSAACAEQGRQLLGELEASLR 3826
+ ++ + KAGA YLPLD PA RL ++Q SR +L+ + A LL L A
Sbjct: 534 VIALLATLKAGAAYLPLDLKQPAGRLADVLQDSRAALLIGATA-----SPLLARL-AEHT 587
Query: 3827 PQLLVWEDVQANPIASH---NPGIHSGPDNLAYVIYTSGSTGLPKGVMVEQRGMLNNQLS 3883
P L + E QA IA+ +P + D+ AYVIYTSGSTG PKGV+VE R +++ +
Sbjct: 588 PLLSLAE--QAEAIAAQPGTSPAVAHSLDDAAYVIYTSGSTGTPKGVVVEHRAIVDYLTA 645
Query: 3884 KVPYLALSEQDVIAQTASQSFDISVWQFLAAPLFGAKVEIVPNVIAHDPQGLLAHVQATG 3943
L +S + D+ Q A G + +V + P L
Sbjct: 646 VHSVLKPPAAARYGLLSSIAADLGHTQLFGALCSGGSLLLVDDESGFSPLALAELFSQHP 705
Query: 3944 ITVLESVPSLIQGMLASDHQALDGLRWMLPT------GEVMPPELAAQWLQRYPQIGLVN 3997
+ VL+ PS + G+L QAL R +LP G+ + P L AQ P + + N
Sbjct: 706 VDVLKITPSHLSGLL----QALPDAR-LLPRSLLVFGGDALSPALLAQVNGLAPGLRVFN 760
Query: 3998 AYGPAECSDDVAFFRVDAASTQGSYLPIGTPTDNNRLYLFGEDQALVPLGAVGELCVAGA 4057
YGP+E + V + Q S + +G P N +L + V G GEL ++GA
Sbjct: 761 HYGPSEAT--VGAIATELTPGQRS-IALGRPLPNRQLRVVDAQGREVATGVSGELLISGA 817
Query: 4058 GVGRGYVGDPVRTALAFIPHPYGAPGERLYRTGDLARQRLDGVLEYVGRIDHQVKIRGYR 4117
+ RGY+ +A F+ R YRTGD R +DG L ++GR+D QVKIRG R
Sbjct: 818 -LARGYLHRDDLSAERFL---RDEQQNRWYRTGDRVRWLVDGQLAFLGRVDSQVKIRGNR 873
Query: 4118 IELGEIEARLHEQAEIRDAAVAVQEGVNGK-HLVGYLVAHQGVSADAALLEQVKQRLRAE 4176
+ELGE+EA++ + + + V ++G LV YLVA Q +SA +++ L
Sbjct: 874 LELGEVEAQIKRLSPLIEQVVVRALELDGSLRLVAYLVASQSLSA-----LKLRNDLGNR 928
Query: 4177 LPEYMVPLHWGWFDSLPHNANGKLDRKALPAIDIGGQYSQAYLAPRNELEDVLAGIWADV 4236
+P+YMVP H+ D LP NGK+D + LP G S ++APRNE+E +LA IW DV
Sbjct: 929 VPDYMVPAHFITLDELPLTRNGKVDAQRLPLPPTTGDDSATHVAPRNEVETLLAAIWQDV 988
Query: 4237 LKAERVGVHDNFFELGGHSLLATQIASRVQKQLQLNVPLRAMFECSTVEALAEYVQGLQG 4296
LK E+VGVHDNFF +GG S+L QI +R +Q L + R +FE T+ +A +
Sbjct: 989 LKREQVGVHDNFFAIGGDSILNLQIIARANQQ-GLKLTPRQLFENRTIADIARVLGADAS 1047
Query: 4297 SALDDDKVD 4305
A+ + D
Sbjct: 1048 HAVAEQLAD 1056
Score = 507 bits (1306), Expect = e-146
Identities = 462/1516 (30%), Positives = 670/1516 (44%), Gaps = 80/1516 (5%)
Query: 1720 PLSYSQQRMWFLWQMEPDSPAYNVGGMARLRGTLHVDAFERALQALIVRHETLRTTFP-S 1778
PLS QQ M ++P S Y + G L A E A + + RH +RT F
Sbjct: 1496 PLSSMQQGMLLHTLLQPHSGIYLMQQRYSWDGVLQRTAMETAWRLFLDRHPMMRTAFWWQ 1555
Query: 1779 IDGVPYQCVAEDSGLHLDWQDFSALSDDACQQRLQQLADDQAHQPFDLERGPLLRACLVK 1838
D P QCV + DWQD L D +Q + Q + Q Q FD+ PL + +
Sbjct: 1556 DDHEPLQCVYRKTAPAFDWQDVRHLDDAQQRQAMDQALEAQRVQGFDMSSAPLTHLRVFQ 1615
Query: 1839 ANEREHFFVLTLHHIVTEGWAMDIFARELGELYEAFVDDRESPLA-PLPVQYLDYSVWQR 1897
+E+ V + HHI+T+ W + +L +Y+A V R+ P+A P + Y
Sbjct: 1616 LDEQRFAVVRSFHHILTDAWCFGLLMEDLLAIYQAVV--RQEPVARPRLRSFRGYM---- 1669
Query: 1898 QWLESGEGARQLAYWKHRLGDEHPVLALPAD----RPRPAVQSHRGELYRFELDPALVAR 1953
WLE + A A+W+ L L D RP A + G++ + L + R
Sbjct: 1670 SWLERQDMAAAHAFWQADLAGFSEPTPLHVDGALARPEQAPEQV-GDVDQ-TLSISQTQR 1727
Query: 1954 VHAFNSQRGLTLFMTMTATLAALLHRYSGQRDLRIGAPVANRIRPES--EGLIGAFLNTQ 2011
+ Q LT + A LL RYSG RD+ G VA R + E ++G F+N+
Sbjct: 1728 LQQLCQQYQLTPNTWIQGAWALLLSRYSGNRDVLFGVTVAGRPTDLAGVEEMVGLFINSL 1787
Query: 2012 VLRCELDGQMTASALLEQVRQAAIEGQSHQDLPFDQLVEALQPPRSSAYNPLFQVMCNVQ 2071
LR ++D + A L+ + + H+ + + PR PLF + +
Sbjct: 1788 PLRIDVDPEAPVGAWLQALLSHNARLREHESASLVDIQRSSNVPRGQ---PLFDSLVVFE 1844
Query: 2072 RWAFQQSRT-LAGMQVDYLVNDASATKFDLYLEVTDLDGRLGCCLTYSRDLFDAPRIARM 2130
S L +D + D T F + + + D RLG L+Y F + RM
Sbjct: 1845 NAPLDISSVQLDAFSID-IYEDRVHTNFPMTVVLYPGD-RLGIRLSYDSQRFSTDTVQRM 1902
Query: 2131 AEHWQQLLVGLLDNPQHRLCELPMLSSAEQQVLTGQL-QGEHDFDLGQTLHGLFAAQAAR 2189
H QLL +LD P+ L L MLS++E++ L + + E DF L Q LFA Q R
Sbjct: 1903 LGHLVQLLSSMLDAPEAPLGTLHMLSASEREQLQVEWNRSEVDFPLDQGYAALFAEQVRR 1962
Query: 2190 TPQAGALTFAGQHLTYAELDQQANRLARALRERGVGPQVRVGLALERSLEMVVGLLAILK 2249
PQ A + LTYAELD++AN +A AL+ G GP+ V L ER L ++ ++ LK
Sbjct: 1963 RPQQIAAVHLHESLTYAELDRRANAVAHALQAAGAGPETLVALFAERGLALLTLMIGTLK 2022
Query: 2250 ADGAYVPLDPEYPLDRLRYMIEDSRIGLLL-SQRALLHTLGELPEGVASWSLEDDAASLA 2308
A A+ LD + P RL ++ L+L +A G LP+ +
Sbjct: 2023 AGAAFQALDIQQPATRLAELLSLGEAPLVLVCDKATAVLDGVLPQLLKQPRCLVAQTLWQ 2082
Query: 2309 AYSDAPLDNLSLPQHQAYLIYTSGSTGKPKGVVVSHGEFAMHCQAVIAAFGMRSDDCELH 2368
+D + +P AY+I+TSGSTG PKGV+V + + A G+ D
Sbjct: 2083 GEVKPSVDYVHIPDQLAYVIFTSGSTGTPKGVMVEQRGMLNNIFGKVPALGLGEHDRLAQ 2142
Query: 2369 FYSINFDAASERLWVPLLCGARVVLRAQGQWGAED---ICQLVREQQVSILGFTPSYGSQ 2425
S FD + L GA V + Q A D + V+ QQ+++L P+
Sbjct: 2143 TASPAFDICVWQFLAAPLVGACVHILPDAQ--AHDPLALLDAVQAQQLTLLETVPALIRG 2200
Query: 2426 LAQYLGGRGEQLPVRLVITGGEALTGEHLQRIRQAFAPQQCFNAYGPTETVVMPLACLAP 2485
+ Q + + +R ++ GEAL Q F NAYGP E
Sbjct: 2201 MLQEVRAQDHLASLRWLLPTGEALPPTLAQDWFARFPSIPLMNAYGPAECSDDVAFYPIT 2260
Query: 2486 EALPADLGSVPIGRVIGSRTAYILDEDLALLPQGGIGELYVGGAGLAQGYHDRPGLTAER 2545
EA D +PIGR + ++LD DL +P G GEL +GG G+ +GY P T E
Sbjct: 2261 EAPSDDCLHMPIGRPTANNQVFVLDADLRCVPIGVPGELCIGGVGVGRGYLGDPQRTREA 2320
Query: 2546 FVADPFSAEGGRLYRTGDLVRLGTDGLVEYVGRADQQVKIRGFRIELGEIESRLLAHEDV 2605
FVA PF G RLYR+GD+ RL DG++EY+GR DQQVKIRG+RIELGEIE+RL+ H V
Sbjct: 2321 FVAHPFQT-GARLYRSGDIGRLRADGVIEYLGRRDQQVKIRGYRIELGEIENRLMQHPAV 2379
Query: 2606 DEAVVLAL-DLPGGKQLVGYLVCRQAT--AGNDVQQLLREAVKADARQHLPDYMVPAHLV 2662
D A VLAL D G QLV + V A G Q LL A + L YMVPA +
Sbjct: 2380 DSAAVLALPDARGALQLVAWYVLDAAAELGGQTAQSLLT----AYLERQLASYMVPARWL 2435
Query: 2663 LLDSLPLMGNGKLDRHALPLPDLEQARQQYQ---APGNEVEAQLAQIWRDVLNVARVGVQ 2719
L LPL NGK+DR AL D++QA AP E LA++W+D+L VA VGV
Sbjct: 2436 ALAQLPLNANGKVDRRALAALDVQQAEPAQGVVVAPRTPTEKVLAELWQDLLGVAGVGVH 2495
Query: 2720 DNFFELGGDSILSIQVVSRARQA-GLQFTPRDLFQHQTIQTLATVV----QLSEAASTVE 2774
D+FF +GG S+L+ Q++SR R+ + R LF+ T+ LA V Q+S+ + V
Sbjct: 2496 DDFFAIGGHSLLATQMLSRIRRRLNVSLPLRTLFEGGTLAQLAQAVDQQAQVSDDSEIVP 2555
Query: 2775 QGLRQGQAGLTPIQH-WFFDSDVPQPQHWNQTVLLEVRQPLVEATLEQALAALVQHHDSL 2833
Q A Q WF D +N + ++ +R L A L+QAL +++ H++L
Sbjct: 2556 VPRNQTLALSYAQQRLWFLDRFEGPNAAYNMSSVVRLRGALDIAALQQALQRVLERHEAL 2615
Query: 2834 RLRFSDAQGRWQAQYVQPGAEQLLWSATVADFNDCQALYTDVQRSLDLQQGPLLRALLVR 2893
R F +G Q + L V + + DLQQ P+LRA L+
Sbjct: 2616 RTTFH-LKGEQPCQVINEAPTLDLTPVNVESHALQSVIDRQSAQPFDLQQAPMLRAHLLH 2674
Query: 2894 DGQGTQRLLLAIHHLVVDGVSWRVLLEDLQALYR------GQPLPAKTHAVGDWAARLAS 2947
G L L +HH+ D S +L+++L Y+ LPA D+A S
Sbjct: 2675 LGTDDHVLQLVLHHIATDAWSMGILIQELITGYQAYASGVNPTLPALPIQYADYAQWQRS 2734
Query: 2948 YAGSDSLRDELAWWQGQLGGVRR--ELPCDHPQGSNLHRHAQTLAIGLDVEQTRQLLQLA 3005
L + +W+ QL G LP D P+ + L T Q+L+
Sbjct: 2735 EPQQRQLARAIDYWRRQLDGAPTLIALPLDAPRPTQPDYQGAALTQQFSPAHT-QVLKAY 2793
Query: 3006 PAAYHTQVNDLLLTALARALCRWSGDEEVLVQLEGHGRDGLFEDMDLTRSVGWFTNAYPL 3065
+ + +LL A L R +G + +V + R E L +G+F N P+
Sbjct: 2794 AQQHKATLFMVLLNAFNSLLQRATGANDFIVGTDLANR----EHSALEPLIGFFVNVLPI 2849
Query: 3066 SLRPLPGEDDAARAGSIKRIKEQ-LRHVPHKGLGYGVLRYLADAAGREQMAALPQARITF 3124
R +D ++R++E L H+ + + L + L Q
Sbjct: 2850 RARL---DDSDTFDHRLQRLREDCLAAFQHQQVPFDKLVETLQPPRTPGVNPLVQVLFVM 2906
Query: 3125 NYLGQFDQQFDSAALFQPLEASAGLAHDLDAPLPNWLSVDGQVY----GGALQLRWTFSA 3180
Q +A+L +GLA + AP D V+ L +RW +
Sbjct: 2907 QNTPQ-----GTASL-------SGLAVEHLAPQQETSKFDLAVFVEEDENGLTVRWVYRT 2954
Query: 3181 ERYDQQTIARLAEGYR 3196
QT+A L G++
Sbjct: 2955 SVLSAQTVADLEHGFQ 2970
Score = 459 bits (1182), Expect = e-132
Identities = 405/1265 (32%), Positives = 601/1265 (47%), Gaps = 91/1265 (7%)
Query: 689 LEPQSAAYNIPAGLHLRGELDVNALHVAFQALVARHESLRTVFS-EENGQALQRILPQQP 747
+EP S Y L + G L + A A+QAL+ RH LR+ F E+ A Q +
Sbjct: 23 VEPDSRVYYQQLSLEMNGPLQLPAFRAAWQALMQRHAVLRSAFLWEDLDDAYQVVQTDVG 82
Query: 748 LSLHRLDLEGHSPEQVAAQRET--EARQPFDLTQGPLLRVTLVRLGDEEHQLWVTLHHIV 805
L L LD +GH+ + A Q+ + QP +L PL+R+TLVRL + L T HHI+
Sbjct: 83 LPLSELDWQGHADPKTALQQLALEQRAQPLELNDSPLMRLTLVRLEPQRWHLIWTFHHII 142
Query: 806 ADGWSLNILLEEFAKLYAARCQGLEANLAPLPLGYADYGSWQRQWLADGEAERQLQYWKA 865
DGWS+ I ++E+ LY G ANLAP Y DY +W LA+ + +W+
Sbjct: 143 MDGWSVGIAIQEWLALYYEHAHGRPANLAPTR-AYRDYIAW----LAEQDMAATESFWRN 197
Query: 866 HLGG-----ELPALDLC----TDHPRASQREHSAARFSLKVPVRLGEALKGLAHQQQASL 916
L LP L TD P A + +A + E L A + +L
Sbjct: 198 QLQDVSEPTPLPDFGLRLVPPTDAPCAERENRLSADET--------EQLAQFARRHHLTL 249
Query: 917 FMVLLAGWQALLQRYSGQADIRVGVPNANRPR--LETQGMVGFFINTQVLRARFDGRHSF 974
++ W LL +++G+ D+ GV A RP VG FINT LR ++ +
Sbjct: 250 NTLIQGAWALLLGQHAGRDDVIYGVTVAGRPENLAAVDSTVGLFINTLPLRVQWADGPAL 309
Query: 975 TQLLTQVRQATLQAQANQDLPFEQLVEALPDAREQGLFQVMFNHQQRDLS-ALRRLPGLL 1033
L Q++ A + + LP +L A EQ LF + + ++ AL + G L
Sbjct: 310 VDWLQQLQHANSDLRHHAYLPLGKLKSMSKIAAEQALFDSILVFENFPVTDALNQDAGGL 369
Query: 1034 AEELAWHSREAKFD-LQLHSEEDHLG---------RLSLAFDYAAELFEASTVERLAHHL 1083
+ A +RE D L L +H +L F Y F + + L+ L
Sbjct: 370 S--FADPNREQATDGLVLTQGRNHFPLSLIVVPGEQLHYLFSYNRSRFSDAEITLLSAQL 427
Query: 1084 LALLEQVCAAPQQALGDVQLL--DEPGRAQLLGWGQAPAAAAQHLLVEQLNEQVRLTPQR 1141
+L + A PQ +G++ + DE + Q LG G P A + L ++ +QV P +
Sbjct: 428 RNVLLAMAAQPQCRVGELDWMGADERQQLQALGCG-TPLAVPEACLHQRFEQQVAAAPDQ 486
Query: 1142 TALVWDGGSLDYAGLHQQANRLAHYLRDKGVGPDTCVAIAIERSPQLLVGLLAILKAGGA 1201
A++ G L YA L Q+ANRL+H+LR +G+G + VA+A+ERS ++ LLA LKAG A
Sbjct: 487 PAILDREGVLSYAELDQRANRLSHHLRAEGIGHHSLVALALERSADFVIALLATLKAGAA 546
Query: 1202 YVPLDVDYPAERLAYMLADCDARLLL--SHSSLLGKLPQVDGVSAIALDQLHLDSWPSHA 1259
Y+PLD+ PA RLA +L D A LL+ + S LL +L + + ++A + + P +
Sbjct: 547 YLPLDLKQPAGRLADVLQDSRAALLIGATASPLLARLAEHTPLLSLAEQAEAIAAQPGTS 606
Query: 1260 PGLHLHGDNLAYVIYTSGSTGQPKGVGNTHAALAERLQWMQTTYALNDSDVLMQKAPISF 1319
P + D+ AYVIYTSGSTG PKGV H A+ + L + + + + I+
Sbjct: 607 PAVAHSLDDAAYVIYTSGSTGTPKGVVVEHRAIVDYLTAVHSVLKPPAAARYGLLSSIAA 666
Query: 1320 DVSVWECFWPLVTGCKLVLAGPGEHRDPQRIAALVQAYGVTTLHFVPPLLQVFVQE-PQA 1378
D+ + F L +G L+L P +A L + V L P L +Q P A
Sbjct: 667 DLGHTQLFGALCSGGSLLLVDDESGFSPLALAELFSQHPVDVLKITPSHLSGLLQALPDA 726
Query: 1379 SACSSLRWVFSGGEALSATLRDRVLQVLPQVQLHNRYGPTETAINVTHWHCQVVDGERS- 1437
VF GG+ALS L +V + P +++ N YGP+E + ++ G+RS
Sbjct: 727 RLLPRSLLVF-GGDALSPALLAQVNGLAPGLRVFNHYGPSEATVGAI--ATELTPGQRSI 783
Query: 1438 PIGRPLGNVLCRVLDDELELSAPGVPGELYLGGAGLARGYLGRPGLTAERFVPQADGNGQ 1497
+GRPL N RV+D + A GV GEL + GA LARGYL R L+AERF+ D
Sbjct: 784 ALGRPLPNRQLRVVDAQGREVATGVSGELLISGA-LARGYLHRDDLSAERFL--RDEQQN 840
Query: 1498 RLYRSGDRARWQVQLEALEYLGRLDQQVKVRGFRVEPEEVQACLLAQAGVEQALVLIHKD 1557
R YR+GDR RW V + L +LGR+D QVK+RG R+E EV+A + + + + +V+ +
Sbjct: 841 RWYRTGDRVRWLVDGQ-LAFLGRVDSQVKIRGNRLELGEVEAQIKRLSPLIEQVVVRALE 899
Query: 1558 AIGAQLVGYYSGSAQPAEVLAV---LAEQLPAYMVPAQLIPLAQMPLGPSGKVDRKALPA 1614
G+ + Y ++Q L + L ++P YMVPA I L ++PL +GKVD + LP
Sbjct: 900 LDGSLRLVAYLVASQSLSALKLRNDLGNRVPDYMVPAHFITLDELPLTRNGKVDAQRLPL 959
Query: 1615 PVW---QQREHVEPRTELQQQVAAIWRDVLNLPRIGLQDDFFALGGHSLLATQIVSRTRQ 1671
P HV PR E++ +AAIW+DVL ++G+ D+FFA+GG S+L QI++R Q
Sbjct: 960 PPTTGDDSATHVAPRNEVETLLAAIWQDVLKREQVGVHDNFFAIGGDSILNLQIIARANQ 1019
Query: 1672 ACDVELPLKALFEASELGAFCAEIARLRAAGERNLQGAITRVDRRQAVPLSYSQQRMWFL 1731
++L + LFE + A+IAR+ A + ++ A+PLS Q+
Sbjct: 1020 Q-GLKLTPRQLFENRTI----ADIARVLGADASH--AVAEQLADGYALPLSAGQRA---- 1068
Query: 1732 WQMEPDSPAYNVGGMARLRGTLHVDAFERALQALIVRHETLRTTFPSIDGVPYQCVAEDS 1791
++E P L L D +AL AL H+ LR F + DG VA +
Sbjct: 1069 -RLE-QGPLTATWRCVALAQPLDRDLLSQALGALQQHHQALRLAFDA-DGQQRVLVAPKA 1125
Query: 1792 GLHLDWQDFSALSDDACQQRLQQLADDQAHQPFDLERGPLLRACLVKANEREHFFVLTLH 1851
+ S D +L LA DL G L A L+ EH +L H
Sbjct: 1126 A--------AITSGDYHPAQLHALA-QAGVDTLDLRAGQSLHASLL----GEH-LLLAAH 1171
Query: 1852 HIVTEGWAMDIFARELGELYEAFVDDRESPLAPLPVQYLDYSVWQRQWLESGEGARQLAY 1911
+ + + + L +L A R LP +++ W R E
Sbjct: 1172 PLCVDESSWSLL---LTDLNLALAQLRLQRPVRLPYTGGNFTQWTRHQQAHAESDALDEA 1228
Query: 1912 WKHRL 1916
W+H L
Sbjct: 1229 WEHWL 1233
Score = 367 bits (943), Expect = e-104
Identities = 329/1104 (29%), Positives = 492/1104 (44%), Gaps = 91/1104 (8%)
Query: 5 FELPLSLVQALAQRAAQTPERIALRFLADTPGEQAVLSYRDLDQRARTIAAALQGRASFG 64
F L A++ + P++IA L ++ L+Y +LD+RA +A ALQ +
Sbjct: 1946 FPLDQGYAALFAEQVRRRPQQIAAVHLHES------LTYAELDRRANAVAHALQAAGAGP 1999
Query: 65 DRAVLLFPS-GPDYVAAFFGCLYAGVIAVPAYPPESARQQHQERLLSIIDDAEPRLLLTV 123
+ V LF G + G L AG A+ QQ RL ++ E L+L
Sbjct: 2000 ETLVALFAERGLALLTLMIGTLKAGA----AFQALDI-QQPATRLAELLSLGEAPLVLVC 2054
Query: 124 AALRDSLQGLEALAADNAPQLLAVDGLDPALAANWREPVLKGDDIAFLQYTSGSTALPKG 183
L G+ P+ L L + V D +A++ +TSGST PKG
Sbjct: 2055 DKATAVLDGVLPQLLKQ-PRCLVAQTLWQGEVKPSVDYVHIPDQLAYVIFTSGSTGTPKG 2113
Query: 184 VQVSHGNLVANEQLIRQGFGIDLNPDDVIVSWLPLYHDMGLIGGLLQPIFSGVPCVLMSP 243
V V ++ N + + + L D + D+ + L P+ CV + P
Sbjct: 2114 VMVEQRGMLNN--IFGKVPALGLGEHDRLAQTASPAFDICVWQFLAAPLVGA--CVHILP 2169
Query: 244 RYFLARPLRWLQAISEYGGTI-SGGPDFAYRLCSERVSEASLAGLDLSRWRVAYSGSEP- 301
PL L A+ T+ P + E ++ LA L RW + + P
Sbjct: 2170 DAQAHDPLALLDAVQAQQLTLLETVPALIRGMLQEVRAQDHLASL---RWLLPTGEALPP 2226
Query: 302 -IRQDSLATFADKFQACGFDPQSFFASYGLAEATLFVSGSRRGQGIAALELDAKAFAANR 360
+ QD A F +YG AE + D AF
Sbjct: 2227 TLAQDWFARFPSI---------PLMNAYGPAECS-----------------DDVAFYPIT 2260
Query: 361 AEPGTGSVLMSCGFPQPGHAVRIVEPQQLQVLGDNQVGEIWAGGPSIARGYWRNPEASAR 420
P + M G P + V +++ L+ + GE+ GG + RGY +P+ +
Sbjct: 2261 EAPSDDCLHMPIGRPTANNQVFVLDAD-LRCVPIGVPGELCIGGVGVGRGYLGDPQRTRE 2319
Query: 421 TFVEMDGQTWLR---TGDLGFIR-EGEVFVTGRLKDMLIVRGQNLYPQDLEKALEREVQV 476
FV QT R +GD+G +R +G + GR + +RG + ++E L + V
Sbjct: 2320 AFVAHPFQTGARLYRSGDIGRLRADGVIEYLGRRDQQVKIRGYRIELGEIENRLMQHPAV 2379
Query: 477 LRKGRVAV----FAVEHQGEEGIGVAVEISRNVQKALKPQDLIKTLRQVVADACRQAPAV 532
+A+ A++ + A E+ ++L L + L A PA
Sbjct: 2380 DSAAVLALPDARGALQLVAWYVLDAAAELGGQTAQSLLTAYLERQL------ASYMVPAR 2433
Query: 533 VLLLNPGALPKTSSGKLQRSACRLRMDDGSLDCYARFPEVSAAGIRATAGDELQARIAAV 592
L L LP ++GK+ R A +LD P A G+ + +A +
Sbjct: 2434 WLAL--AQLPLNANGKVDRRAL------AALDVQQAEP---AQGVVVAPRTPTEKVLAEL 2482
Query: 593 WRDILKVEAVAADDHFLLLGGNSIAATQATARLADELGIDLSLRTLFEAPVLADYSKAV- 651
W+D+L V V D F +GG+S+ ATQ +R+ L + L LRTLFE LA ++AV
Sbjct: 2483 WQDLLGVAGVGVHDDFFAIGGHSLLATQMLSRIRRRLNVSLPLRTLFEGGTLAQLAQAVD 2542
Query: 652 --AQIIADGAAATTAITTLERAQALPQSLAQNRLWLLWQLEPQSAAYNIPAGLHLRGELD 709
AQ+ D + I + R Q L S AQ RLW L + E +AAYN+ + + LRG LD
Sbjct: 2543 QQAQVSDD-----SEIVPVPRNQTLALSYAQQRLWFLDRFEGPNAAYNMSSVVRLRGALD 2597
Query: 710 VNALHVAFQALVARHESLRTVFSEENGQALQRILPQQPLSLHRLDLEGHSPEQVAAQRET 769
+ AL A Q ++ RHE+LRT F + Q Q I L L +++E H+ + V +
Sbjct: 2598 IAALQQALQRVLERHEALRTTFHLKGEQPCQVINEAPTLDLTPVNVESHALQSVI---DR 2654
Query: 770 EARQPFDLTQGPLLRVTLVRLGDEEHQLWVTLHHIVADGWSLNILLEEFAKLYAARCQGL 829
++ QPFDL Q P+LR L+ LG ++H L + LHHI D WS+ IL++E Y A G+
Sbjct: 2655 QSAQPFDLQQAPMLRAHLLHLGTDDHVLQLVLHHIATDAWSMGILIQELITGYQAYASGV 2714
Query: 830 EANLAPLPLGYADYGSWQRQWLADGEAERQLQYWKAHLGGELPALDLCTDHPRASQREHS 889
L LP+ YADY WQR + R + YW+ L G + L D PR +Q ++
Sbjct: 2715 NPTLPALPIQYADYAQWQRSEPQQRQLARAIDYWRRQLDGAPTLIALPLDAPRPTQPDYQ 2774
Query: 890 AARFSLKVPVRLGEALKGLAHQQQASLFMVLLAGWQALLQRYSGQADIRVGVPNANRPRL 949
A + + + LK A Q +A+LFMVLL + +LLQR +G D VG ANR
Sbjct: 2775 GAALTQQFSPAHTQVLKAYAQQHKATLFMVLLNAFNSLLQRATGANDFIVGTDLANREHS 2834
Query: 950 ETQGMVGFFINTQVLRARFDGRHSFTQLLTQVRQATLQAQANQDLPFEQLVEALPDAREQ 1009
+ ++GFF+N +RAR D +F L ++R+ L A +Q +PF++LVE L R
Sbjct: 2835 ALEPLIGFFVNVLPIRARLDDSDTFDHRLQRLREDCLAAFQHQQVPFDKLVETLQPPRTP 2894
Query: 1010 G---LFQVMFNHQQRDLSALRRLPGLLAEELAWHSREAKFDLQLHSEEDHLGRLSLAFDY 1066
G L QV+F Q L GL E LA +KFDL + EED G L++ + Y
Sbjct: 2895 GVNPLVQVLF-VMQNTPQGTASLSGLAVEHLAPQQETSKFDLAVFVEEDENG-LTVRWVY 2952
Query: 1067 AAELFEASTVERLAHHLLALLEQV 1090
+ A TV L H ALL+ +
Sbjct: 2953 RTSVLSAQTVADLEHGFQALLDNL 2976
Score = 114 bits (285), Expect = 5e-28
Identities = 161/586 (27%), Positives = 251/586 (42%), Gaps = 77/586 (13%)
Query: 325 FASYGLAEATLFVSGSRRGQGIAALELDAKAFAANRAEPGTGSVLMSCGFPQPGHAVRIV 384
F YG +EAT+ G A EL PG S+ + G P P +R+V
Sbjct: 759 FNHYGPSEATV---------GAIATELT----------PGQRSIAL--GRPLPNRQLRVV 797
Query: 385 EPQQLQVLGDNQVGEIWAGGPSIARGYWRNPEASARTFVEMDGQT-WLRTGD-LGFIREG 442
+ Q +V GE+ G ++ARGY + SA F+ + Q W RTGD + ++ +G
Sbjct: 798 DAQGREV-ATGVSGELLISG-ALARGYLHRDDLSAERFLRDEQQNRWYRTGDRVRWLVDG 855
Query: 443 EVFVTGRLKDMLIVRGQNLYPQDLEKALEREVQVLRKGRVAVFAVEHQGEEGIGVAVEIS 502
++ GR+ + +RG L ++E ++R ++ + V V A+E G + VA ++
Sbjct: 856 QLAFLGRVDSQVKIRGNRLELGEVEAQIKRLSPLIEQ--VVVRALELDGSLRL-VAYLVA 912
Query: 503 RNVQKALKPQDLIKTLRQVVADACRQAPAVVLLLNPGALPKTSSGKLQRSACRLRMDDGS 562
ALK L L V D PA + L+ LP T +GK+ L G
Sbjct: 913 SQSLSALK---LRNDLGNRVPDY--MVPAHFITLDE--LPLTRNGKVDAQRLPLPPTTGD 965
Query: 563 LDCYARFPEVSAAGIRATAGDELQARIAAVWRDILKVEAVAADDHFLLLGGNSIAATQAT 622
+ +E++ +AA+W+D+LK E V D+F +GG+SI Q
Sbjct: 966 -----------DSATHVAPRNEVETLLAAIWQDVLKREQVGVHDNFFAIGGDSILNLQII 1014
Query: 623 ARLADELGIDLSLRTLFEAPVLADYSKAVAQIIADGAAATTAIT-TLERAQALPQSLAQN 681
AR A++ G+ L+ R LFE +AD ++ + GA A+ A+ L ALP S Q
Sbjct: 1015 AR-ANQQGLKLTPRQLFENRTIADIARVL------GADASHAVAEQLADGYALPLSAGQR 1067
Query: 682 -RLWLLWQLEPQSAAYNIPAGLHLRGELDVNALHVAFQALVARHESLRTVFSEENGQALQ 740
RL + P +A + A L LD + L A AL H++LR F + +GQ
Sbjct: 1068 ARL----EQGPLTATWRCVA---LAQPLDRDLLSQALGALQQHHQALRLAF-DADGQQRV 1119
Query: 741 RILPQQPLSLHRLDLEGHSPEQVAAQRETEARQPFDLTQGPLLRVTLVRLGDEEHQLWVT 800
+ P+ + + P Q+ A + DL G L +L LG+ L +
Sbjct: 1120 LVAPKAA----AITSGDYHPAQLHALAQAGV-DTLDLRAGQSLHASL--LGE---HLLLA 1169
Query: 801 LHHIVADGWSLNILLEEFAKLYAARCQGLEANLAPLPLGYADYGSWQRQWLADGEAERQL 860
H + D S ++LL + L A Q LP ++ W R A E++
Sbjct: 1170 AHPLCVDESSWSLLLTD---LNLALAQLRLQRPVRLPYTGGNFTQWTRHQQAHAESDALD 1226
Query: 861 QYWKAHLG-GELPALDLCTDHPRASQREHSAARFSLKVPVRLGEAL 905
+ W+ L L L L H +S E S + + RL + L
Sbjct: 1227 EAWEHWLQYAGLDTLQLPDSHQPSSVVEQSVSAATSSELKRLTDVL 1272
Score = 107 bits (268), Expect = 5e-26
Identities = 104/404 (25%), Positives = 172/404 (42%), Gaps = 37/404 (9%)
Query: 3230 DALPVPAAQIEDVYPLTPMQEGMLLHTLLEPGTGLYYMQDRYRINSALDPERFAQAWQAV 3289
+ +PVP Q L+ Q+ + E Y M R+ ALD QA Q V
Sbjct: 2552 EIVPVPRNQ---TLALSYAQQRLWFLDRFEGPNAAYNMSSVVRLRGALDIAALQQALQRV 2608
Query: 3290 VARHEALRASFSWNSGEAMLQIIHKPGNLAVDYQDWRGLADDAQEQRLQALHKQEREAGF 3349
+ RHEALR +F GE Q+I++ L + + + LQ++ ++ F
Sbjct: 2609 LERHEALRTTFHLK-GEQPCQVINEAPTLDLT-------PVNVESHALQSVIDRQSAQPF 2660
Query: 3350 ALLSEAPFHLRLVRVAEERYWFMMSNHHILIDAWCRSLLMNDFFEVYQALGEGRQAQLP- 3408
L L+ + + + + HHI DAW +L+ + YQA G LP
Sbjct: 2661 DLQQAPMLRAHLLHLGTDDHVLQLVLHHIATDAWSMGILIQELITGYQAYASGVNPTLPA 2720
Query: 3409 VPPRYRDYIGWL----QRQGLDDARAWWQANLAGFERATAIPSD--RPLRHDHAGSGMV- 3461
+P +Y DY W Q++ L A +W+ L G A+P D RP + D+ G+ +
Sbjct: 2721 LPIQYADYAQWQRSEPQQRQLARAIDYWRRQLDGAPTLIALPLDAPRPTQPDYQGAALTQ 2780
Query: 3462 -VGDCYTRLEMNDGVRLRELAQAHQLTVNTFAQAAWALVLSRYSGDRDVAFGVTVAGRPV 3520
+T++ L+ AQ H+ T+ A+ +L R +G D G +A R
Sbjct: 2781 QFSPAHTQV-------LKAYAQQHKATLFMVLLNAFNSLLQRATGANDFIVGTDLANREH 2833
Query: 3521 SMPQMQRTVGLFINSVALRVQLPAASERCSVRQWLQGLLQSNMELREYEYLP---LVAIQ 3577
S ++ +G F+N + +R +L + + LQ L + + +++ +P LV
Sbjct: 2834 S--ALEPLIGFFVNVLPIRARL---DDSDTFDHRLQRLREDCLAAFQHQQVPFDKLVETL 2888
Query: 3578 ACSELPKGQPLFDSLFVFENAPVETAVLN--HAQHLNASSDSGR 3619
P PL LFV +N P TA L+ +HL ++ +
Sbjct: 2889 QPPRTPGVNPLVQVLFVMQNTPQGTASLSGLAVEHLAPQQETSK 2932
Score = 61.2 bits (147), Expect = 5e-12
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 11 LVQALAQRAAQTPERIALRFLADTPGEQAVLSYRDLDQRARTIAAALQGRA-SFGDRAVL 69
L Q Q+ A P++ A+ + VLSY +LDQRA ++ L+ L
Sbjct: 472 LHQRFEQQVAAAPDQPAIL------DREGVLSYAELDQRANRLSHHLRAEGIGHHSLVAL 525
Query: 70 LFPSGPDYVAAFFGCLYAGVIAVPAYPPESARQQHQERLLSIIDDAEPRLLLTVAALRDS 129
D+V A L AG AY P +Q RL ++ D+ LL+ A
Sbjct: 526 ALERSADFVIALLATLKAGA----AYLPLDLKQP-AGRLADVLQDSRAALLIGATA---- 576
Query: 130 LQGLEALAADNAPQLLAVDGLDPALAANWREPVLKG--DDIAFLQYTSGSTALPKGVQVS 187
L A A++ P L + + A P + DD A++ YTSGST PKGV V
Sbjct: 577 -SPLLARLAEHTPLLSLAEQAEAIAAQPGTSPAVAHSLDDAAYVIYTSGSTGTPKGVVVE 635
Query: 188 HGNLV 192
H +V
Sbjct: 636 HRAIV 640