Pairwise Alignments

Query, 1042 a.a., Multidrug efflux RND transporter MexD from Pseudomonas putida KT2440

Subject, 1044 a.a., multidrug transporter from Pseudomonas simiae WCS417

 Score =  948 bits (2450), Expect = 0.0
 Identities = 503/1041 (48%), Positives = 689/1041 (66%), Gaps = 6/1041 (0%)

Query: 1    MSRFFIHRPNFAWVVALFISLAGLLVIPSLPVAQYPNVAPPQISITASYPGASAKVMVES 60
            M+ FFI RP FAWV+A+ I L G L I  LP+ QYP++APP + I+A+Y GASAK + +S
Sbjct: 1    MAHFFIDRPIFAWVIAIVIMLGGSLSISQLPLEQYPDIAPPTVKISATYTGASAKTVEDS 60

Query: 61   VTSIIEQSLNGAKGLLYYESTNNSNGVAEVMVTFEPGTDPDMAQVDVQNRLKQAEARMPQ 120
            VT +IEQ + G   L Y  +T++S G A + +TF  GTDPD+AQ+ VQN+L+QAE+R+PQ
Sbjct: 61   VTQVIEQQMKGLDNLTYMSATSSSAGSASISLTFTAGTDPDVAQMQVQNKLQQAESRLPQ 120

Query: 121  AVLTQGLKVEQASSGFLLIYALTSTAGNRGDTTALADYAARNINNELLRVPGVGKLQFFA 180
            +V ++GL V +  S FL+I AL S   +   T  + DY +  + + + R+ GVG +Q   
Sbjct: 121  SVQSEGLTVTKGGSDFLMIVALASDDPSVTGTQ-IGDYISTTLLDSISRIDGVGDVQTLG 179

Query: 181  SEAAMRVWVDPQKLVGYGLSIDDINSAIRGQNVQVPAGSFGSTPGASEQELTATLAVQGT 240
            S  AMR+W+DP  L  Y L   DI+SA+  QN +V AG  G+ P    Q+L AT++ +  
Sbjct: 180  SGYAMRIWLDPALLEKYALMPSDISSALEAQNTEVSAGQLGALPAIKGQQLNATISARSK 239

Query: 241  LDTPEAFAGIVLRANPDGSSVRLGDVARMAIGSENYNLSARLNGHPAVAGAVQLAPGANA 300
            L T + F  +V+++N DG+ V LGDVA + +GSE+Y++S  LNG PA A  VQLA GANA
Sbjct: 240  LQTVDEFRKVVVKSNSDGAVVLLGDVATLELGSESYDISTALNGKPAAAMGVQLAAGANA 299

Query: 301  IQTATLVKERLAELSQFFPEGVEYS--VPYDTSRFVDVAIEKVIHTLIEAMVLVFLVMFL 358
            +     VK +L E+  F+P  ++    + YDT+ FV ++IE+V+  L EA+VLV L+MFL
Sbjct: 300  LNVGKAVKAKLKEMEPFYPTEMQLKNVIAYDTTPFVSLSIEEVVKALGEAIVLVVLIMFL 359

Query: 359  FLQNVRYTLVPSIVVPVCLLGTLMIMKLLGFSVNMMTMFGMVLAIGILVDDAIVVVENVE 418
            FLQ++R TL+P+I VPV LLGT  ++ L G+S+N +TMF MVLAIG+LVDDAIVVVENVE
Sbjct: 360  FLQSLRATLIPAITVPVVLLGTFGVLALFGYSINTLTMFAMVLAIGLLVDDAIVVVENVE 419

Query: 419  RLMAEEGLSPVEATIKAMGQVSGAIIGITLVLAAVFLPLAFMSGSVGVIYQQFSVSLAVS 478
            RLM E GLSPV AT ++M ++SGA++GITLVL+AVF+P+AF  GS G+IY+QFSV++  +
Sbjct: 420  RLMGE-GLSPVAATRQSMREISGALVGITLVLSAVFIPMAFFGGSTGIIYRQFSVTIVSA 478

Query: 479  ILFSGFLALTFTPALCATLLKPVP-HGHHEKAGFFGAFNRGFARVTERYSLLNSELVARA 537
            ++ S  +A+T TPALCATLLK     GH  + GFFG FNR F R +  Y      ++ R 
Sbjct: 479  MVLSVLVAMTLTPALCATLLKARNGKGHGAQHGFFGWFNRTFERASAGYERWVGVVLRRW 538

Query: 538  GRWMLAYVGILVVLGYSYLRLPEAFVPAEDLGYSVVDVQLPPGASRVRTDHTAEALEKFL 597
            GR +L Y  +LVV+   Y+ L  +F+P ED G  +  +QLP GA+  RT    +  E ++
Sbjct: 539  GRSLLLYGLVLVVMAVGYVSLATSFLPDEDQGILLAQIQLPVGATDSRTQAVIKQFEDYI 598

Query: 598  MSRDAVANSFIVSGFSFSGQGDNAALAFPTFKDWSQRD-KAQSAEAETAAINAQFAANGD 656
            + +  V     +SG    G   N A AF   KDWS+R    Q A A         ++ GD
Sbjct: 599  LQQPEVEAMISISGLGMGGNSQNTARAFIRLKDWSERGGSGQGAAAIAQRATLALSSIGD 658

Query: 657  GAITAVMPPPIDGLGNSGGFALRLMDRGGLGREALLAARDQLLARANGNPVILYAMMEGL 716
                 + PP + GLG S GF L+L D GGLG +AL+AAR+Q L  A  +  +L     GL
Sbjct: 659  ADAFVMQPPTVRGLGQSSGFDLQLKDLGGLGHDALVAAREQFLELARKDARLLGVRSNGL 718

Query: 717  AEAPQLRLHIDREKARALGVSFEAINSTLATAFGSAVINDFTNAGRQQRVVVQAEQGERM 776
             +APQL++ ID  KA AL +S   INSTLATA G   +NDF N GR ++V VQ +   RM
Sbjct: 719  DDAPQLKVSIDDRKAGALSLSTSDINSTLATALGGTYVNDFLNQGRVKKVYVQGQASSRM 778

Query: 777  TPESVLRLYAPNANGEQVPFSAFVTTQWEEGPVQLVRYNGYPSIRIAGDASPGHSTGQAM 836
                +   +  N+N E VPFS+F ++ W  G   L RYNG  S+ I GD +PG S+G AM
Sbjct: 779  QAADLDHWFVRNSNNEMVPFSSFASSTWGYGSPLLERYNGNASLEIVGDPAPGVSSGDAM 838

Query: 837  AEMERLVSELPPGIGYAWTGLSYQEKVSSGQAASLFALAILVVFLLLVALYESWAIPLTV 896
            A +E +V +LP GIGY WTG SYQ ++S  QA  L+ +++L VFL L ALYESW++P +V
Sbjct: 839  AAVEAIVRQLPQGIGYEWTGQSYQLRLSGSQAPLLYGISVLFVFLCLAALYESWSVPFSV 898

Query: 897  MLIVPIGALGAVWAVTLTGMPNDVYFKVGLITIIGLAAKNAILIVEFAKELWEKGYSLCD 956
            +L+VP+G +GAV A  + G+ NDVYF+VGL+T +GLAAKNAILIVEFAK L E+G S+ D
Sbjct: 899  ILVVPLGVIGAVLATRVAGLSNDVYFQVGLLTTVGLAAKNAILIVEFAKHLQEQGSSVID 958

Query: 957  AAIEAARLRFRPIVMTSMAFILGVVPLAIASGAGAASQRAIGTGVIGGMLSATLLGVVFV 1016
            A + A R R RPI+MTS+AF+ GV+PLA+++GAG+A ++AIGTGV+GGM SAT+LG+ FV
Sbjct: 959  ATLVAVRQRLRPILMTSLAFMFGVLPLALSTGAGSAGRQAIGTGVLGGMFSATVLGIFFV 1018

Query: 1017 PVCFVWVLTLLKRKPSPVQQA 1037
            P+ FV +     R  S  Q A
Sbjct: 1019 PLFFVLIRGRFGRVRSANQSA 1039