Pairwise Alignments

Query, 869 a.a., bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase from Pseudomonas putida KT2440

Subject, 424 a.a., 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) from Variovorax sp. SCN45

 Score = 94.7 bits (234), Expect = 1e-23
 Identities = 114/463 (24%), Positives = 185/463 (39%), Gaps = 63/463 (13%)

Query: 383 TLAQKMVGRACGLPEGQGVRPGAYCEPKMTTVGSQDTTGPMT-RDELKDLACLGFSADLV 441
           TLAQK++ RA G      V  G      +      D++GP   +  L++L    +    +
Sbjct: 9   TLAQKLIARASGRDH---VAVGEIVTCDVDLAMFHDSSGPRRLKPMLEELGAQIWDRSRI 65

Query: 442 MQSFCHTAAYPKPIDVTTHHTLPDFIRTRGGVSLRPGDGIIHSWLNRM--LMPDTVGTGG 499
           +    H                 D+ R +    +    GI H  + +   + P  +  GG
Sbjct: 66  VLVMDHYVPERDDDSRRIVRIARDWARDQQLPHVYDSQGICHVVVPQHGHIRPGMLCVGG 125

Query: 500 DSHTRFPIGISFPA-----GSGLVAFAAATGVMPLDMPESILVRFKGKLQPGITLRD-LV 553
           DSH+  P G +F A     GS  +     TG + L +PE++ + + GKL  G+T +D ++
Sbjct: 126 DSHS--PTGGAFGAYMFGVGSTEMLGVLVTGQIWLRVPETLQMWWDGKLSAGVTAKDMML 183

Query: 554 HAIPYYAIQKGLLTVEKKGKKNAFSGRILEIEGLDDLTVEQAFELSDASAERSAAGCTIK 613
           H I  + +  G      + +   F+G       +  L++++   LS+ SAE  A    I 
Sbjct: 184 HMIGRFGMNGG------RYQAVEFAG-----PAVMALSMQERMTLSNMSAELGAQAGLI- 231

Query: 614 LPEKAIAEYLQS----NITLLRWMIGEGYGDARTLERRAQAMEAWLAKPELLSADADAEY 669
            P+   A +L       + +  W   EG                         AD     
Sbjct: 232 APDATTAAFLAQAGAPPVDMTPWFTDEG-------------------------ADLTRHR 266

Query: 670 AEIIEIDLADVKEPVLCAPNDPDDARLLSSVQGEKIDEVFIGSCM-TNIGHFRAAGKLLE 728
            +      A   EP + AP+ P ++  +S      +D  +IG+C    +   RAA ++L 
Sbjct: 267 FD------ASALEPHIAAPHSPANSHGVSRYADTPVDVAYIGACTGAKLDDLRAAAQVLR 320

Query: 729 KVKGGIPTRLWLAPPTKMDAHQLTEEGYYGIYGKAGARMEMPGCSLCMGNQARVQTGSTV 788
             K     RL +AP +  D  Q  EEG   +   AGA +    C  C G    +    TV
Sbjct: 321 GHKVAAGIRLIVAPASIQDQEQAREEGVLQVLMDAGAELFPTACGACSGYGDPMGDDVTV 380

Query: 789 VSTSTRNFPNRLGDAT-NVYLASAELAAVASIIGKLPTVEEYM 830
           +ST+ RNF  R+G  T  VYL S    A A++ G++    E +
Sbjct: 381 ISTTARNFKGRMGSPTAQVYLGSPYTVAAAALRGRVTDPREVL 423