Pairwise Alignments

Query, 862 a.a., aconitate hydratase 1 from Pseudomonas putida KT2440

Subject, 955 a.a., Aconitate hydratase (EC 4.2.1.3) from Variovorax sp. SCN45

 Score =  637 bits (1643), Expect = 0.0
 Identities = 380/921 (41%), Positives = 523/921 (56%), Gaps = 97/921 (10%)

Query: 32  DGLPYTSRVLAENLVRRCDPATLDASLSQLIER-----KRDLDFPWFPARVVCHDILGQT 86
           D LP + R++ E+++R CD   + A   + +       +R  + P+   RVV  D  G  
Sbjct: 40  DRLPVSIRIVLESVLRNCDGQKVSAKHVEELAHWAPNAERTDEIPFVVTRVVLQDFTGVP 99

Query: 87  ALVDLAGLRDAIADKGGDPAQVNPVVPVQLIVDHSLAVECGGFDPQAFEKNRAIEDRRNE 146
            L DLA +R   A  G  P  + P+VPV L+VDHS+ V+  G  P+A + N  +E +RN 
Sbjct: 100 LLADLAAMRSVAAKLGKSPKTIEPLVPVDLVVDHSVMVDYYG-TPKALDLNMKLEFQRNN 158

Query: 147 DRFHFINWTKKAFKNVDVIQPGNGIMHQINLEKM------SPVVHSDRGVAYPDTCVGTD 200
           +R+ F+ W  +AF    V+ PG GI+HQ+NLE        SP    D+   YPD+ VGTD
Sbjct: 159 ERYQFMKWGMQAFDTFRVVPPGFGIVHQVNLEYFARGVYQSPYDKGDKPTYYPDSLVGTD 218

Query: 201 SHTPHVDALGVIAIGVGGLEAENVMLGRASWMRLPEIVGVELTGKLAPNITATDLVLALT 260
           SHT  ++ +GV+  GVGG+EAE  MLG+  +M  P++VG ELTGKL   +TATDLVL +T
Sbjct: 219 SHTTMINGIGVVGWGVGGIEAEAAMLGQPVYMLTPDVVGFELTGKLREGVTATDLVLYVT 278

Query: 261 EFLRKQKVVGAYLEFHGEGARALTLGDRATISNMAPEYGATAAMFAIDQQTIDYLRLTGR 320
             LR +KVVG ++EF G GA ++ + DRATI NMAPEYGAT   F +D+ T+ Y   TGR
Sbjct: 279 AILRAEKVVGKFVEFFGPGAASIAVPDRATIGNMAPEYGATMGFFPVDEMTVAYFEGTGR 338

Query: 321 EEQQVKLVETYAKATGLWADSLGGAV-YERTLSFDLSSVVRNMAGPSNPHARV-----AT 374
            +++V+  E Y KA GL+     G + Y + +  DL +V  ++AGP  P  R+     AT
Sbjct: 339 TKEEVERFEAYYKAQGLFGMPAPGDIDYTKVVRLDLGTVSPSLAGPKRPQDRIDLGHLAT 398

Query: 375 S-------------------------DLAAKGIAGSWEEVP------------------- 390
                                      LAA G +G  E  P                   
Sbjct: 399 KFSELYSKPNDANGFNQPADKLKLRYPLAAAGKSGDDEAAPPPAGAPLDVVEMVANRSTK 458

Query: 391 --------------GQMP--DGAVIIAAITSCTNTSNPRNVIAAGLIARNANKLGLTRKP 434
                         GQ+   +G V+IAAITSCTNTSNP  ++AAGL+A+ A + GLT KP
Sbjct: 459 AAAHVSATAPSAPKGQVTIGNGDVLIAAITSCTNTSNPSVMLAAGLLAKKAVEAGLTVKP 518

Query: 435 WVKSSLAPGSKAVQLYLEEAGLEKELEQLGFGIVAFACTTCNGMSGALDPVIQQEIIDRD 494
            VK+SLAPGS+ V  YLE+AGL   LE+LGF +  + CTTC G +G L P I + I   D
Sbjct: 519 HVKTSLAPGSRIVTEYLEKAGLLPYLEKLGFYLAGYGCTTCIGNAGDLTPEINEAITKND 578

Query: 495 LYATAVLSGNRNFDGRIHPYAKQAFLASPPLVVAYAIAGTIRFDIEKDVLGV-VDGKEIR 553
           L   AVLSGNRNF+ RIHP  K  FLASPPLVVA+AIAG +  D+  + +G    GK++ 
Sbjct: 579 LIGAAVLSGNRNFEARIHPNLKANFLASPPLVVAFAIAGNVMTDLMTEPVGKGKGGKDVY 638

Query: 554 LKDIWPSDEEIDAVVRAAVKPEQFRKVYIPMFAIEEDRGP-------KVAPLYDWRPMST 606
           L DIWP+ +EID  +R A+  + FR  Y     ++ D G            +YDW P ST
Sbjct: 639 LGDIWPTPKEIDDNLRYAMNAKSFRANY---DKVKTDPGKFWTSIKGTNGQVYDW-PKST 694

Query: 607 YIRRPPYWEG----ALAGERTLRGMRPLAVLPDNITTDHLSPSNAIMLDSAAGEYLAKMG 662
           YI  PP++EG      A +   +G R +A+  D+ITTDH+SP+ +I   S AG +L   G
Sbjct: 695 YIAEPPFFEGFKMKPHASDAGFKGARIMALFGDSITTDHISPAGSIKESSPAGIWLKANG 754

Query: 663 LPEEDFNSYATHRGDHLTAQRATFANPKLFNEMVRND-DGSVKQGSLARIEPEGKVTRMW 721
           + + DFNSY + RG+H    R TFAN ++ N M+  D +G+ ++G +   +P  +   ++
Sbjct: 755 VAKADFNSYGSRRGNHDVMMRGTFANVRIKNLMIPPDANGTQEEGGVTLFQPGNEKMFIY 814

Query: 722 EAIETYMQRKQPLIIVAGADYGQGSSRDWAAKGVRLAGVEAIVAEGFERIHRTNLVGMGV 781
           +A   YM+   P ++  G +YG GSSRDWAAKG +L G++A+VA  FERIHR NLVGMGV
Sbjct: 815 DAAMKYMEAGVPTVVFGGEEYGTGSSRDWAAKGTQLLGIKAVVARSFERIHRANLVGMGV 874

Query: 782 LPLEFKPGTDRKTLGLDGSETYDVL--GARTPRATLTLVVTRANGECLEVPVTCRLDTAE 839
           LPL+F+     +TLGL G E  DV+      P+  + LVV R +G   EV V  R+DT  
Sbjct: 875 LPLQFRGADSWQTLGLTGDEKIDVVIGSELKPQMDVKLVVHRPDGTHQEVTVRLRIDTPI 934

Query: 840 EVSIYEAGGVLQRFAQDFLEA 860
           EV  Y+ GG+L    +  L A
Sbjct: 935 EVDYYKHGGILPFVLRQLLAA 955