Pairwise Alignments

Query, 504 a.a., putative EmrB/QacA family drug resistance transporter from Pseudomonas putida KT2440

Subject, 510 a.a., Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system from Variovorax sp. SCN45

 Score =  217 bits (553), Expect = 7e-61
 Identities = 143/484 (29%), Positives = 233/484 (48%), Gaps = 10/484 (2%)

Query: 19  LFGCFMAGMNVHVTSAALPEIRGSLGASFEEGSWISTAYLVAEIVMIPLTAWLVDVFSLR 78
           +    M  ++  + + ALP ++GSL AS ++ +W+ T+Y+VA  + +PLT WL   +  R
Sbjct: 20  MLATIMQALDTTIANVALPHMQGSLQASQDQITWVLTSYIVASAIALPLTGWLCGHWGRR 79

Query: 79  RVMWTGSLIFLIASVACSWAPNLEAMIVIRVIQGAAGAVLIPLSFQLIITELPASKMAMG 138
           RV     + F +AS  C  A +L  ++  R++QG  GA L+PLS  +++   P  K+   
Sbjct: 80  RVFIISVIGFTVASALCGLATSLVGIVAARLLQGIFGAALVPLSQAVLLDINPREKVGQA 139

Query: 139 MALFSLANSVAQAAGPSIGGWLTDAYSWRWIFYLQLFPGIALLLAIA-WSIEAKPMKLEL 197
           MA++     V    GP +GGWLT+ + WRW+F++ L  GI     IA +  E++P   +L
Sbjct: 140 MAIWGAGIMVGPILGPLLGGWLTENFDWRWVFFINLPVGIFAFWGIARYLPESRPQGEKL 199

Query: 198 LRKGDWLGIAAMVIGLGGLQIVLEEGGRLDWFGSPLIVGMSVVAAIALVVFVV-TQLFGQ 256
               D  G   + + +G LQ+ L+ G +LDWF S  I   +  A +A   FVV T     
Sbjct: 200 ----DIFGFVTLSLAIGMLQLFLDRGEQLDWFDSWEIKLEAAAALVAFGFFVVHTWTVQG 255

Query: 257 RAFINLRLLGHYNFGVASVAMFIFGAATFGLVFLVPNYLSQLQGFSAHDVGVALIAYGVV 316
            +F +  LL   NF    +  FI G   F  + L+PN+L  L G+     G      GV 
Sbjct: 256 VSFFDRDLLKDRNFVTGLLFAFIVGMILFATMALLPNFLQGLMGYPVVYTGQVTAPRGVG 315

Query: 317 QLLLAPLMPRLMGWTSAKFMVASGFLIMALGCWLGAGLSADSADNVIIPSTVVRGIGQPF 376
            ++   ++ RL+     + ++A GF + A   +    L+      +II S  ++G+G  F
Sbjct: 316 TMIAMIIVGRLVQKVDVRAIMAVGFGLTAFSLYQMTRLTLQMDSTLIIVSGFIQGLGIGF 375

Query: 377 IMVALSVLAVAGLDKREAGSASAVFSMLRNLGGAIGTAGLTQLVATRERFHSERIHEQVT 436
             V LS    A L  R     + +FS+LRN+G ++G + + Q + T     S + H Q+ 
Sbjct: 376 TFVPLSTATFATLAPRLRNQGTPIFSLLRNIGSSVGIS-IVQALLTE---GSSKAHAQIA 431

Query: 437 LFEPSVQARINQTVQSWLPPQQQMLEALEATIRREAYLMAYSDAFYLACLALVGCALAAL 496
                    ++   Q   P     L  L A + R+  L+ Y D F +  +  V      L
Sbjct: 432 ATVAPGNQALSTLPQMMSPDTMTGLALLNAEVTRQGALVGYLDDFAIMMIITVLAIPLLL 491

Query: 497 LLRA 500
           L+R+
Sbjct: 492 LIRS 495



 Score = 35.0 bits (79), Expect = 6e-06
 Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 6/144 (4%)

Query: 18  GLFGCFMAGMNVHVTSAALPE-IRGSLGASFEEGSWISTAYLVAEIVMIPLTAWLVDVFS 76
           GL   F+ GM +  T A LP  ++G +G        ++    V  ++ + +   LV    
Sbjct: 272 GLLFAFIVGMILFATMALLPNFLQGLMGYPVVYTGQVTAPRGVGTMIAMIIVGRLVQKVD 331

Query: 77  LRRVMWTG---SLIFLIASVACSWAPNLEAMIVIRVIQG-AAGAVLIPLSFQLIITELPA 132
           +R +M  G   +   L      +   +   +IV   IQG   G   +PLS     T  P 
Sbjct: 332 VRAIMAVGFGLTAFSLYQMTRLTLQMDSTLIIVSGFIQGLGIGFTFVPLSTATFATLAPR 391

Query: 133 SKMAMGMALFSLANSVAQAAGPSI 156
            +   G  +FSL  ++  + G SI
Sbjct: 392 LR-NQGTPIFSLLRNIGSSVGISI 414