Pairwise Alignments

Query, 799 a.a., cadmium translocating P-type ATPase from Pseudomonas putida KT2440

Subject, 745 a.a., Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) from Variovorax sp. SCN45

 Score =  762 bits (1968), Expect = 0.0
 Identities = 432/744 (58%), Positives = 530/744 (71%), Gaps = 27/744 (3%)

Query: 69  PTRTLELQIGGMTCASCVGRVERALGKLAGVEQVSVNLASERAHLEVLAALDDNLLID-- 126
           P  TL+L +GGMTCASCV RVERAL  + GV+ VSVNLA+E A   ++AA  D++ +   
Sbjct: 8   PQTTLDLSVGGMTCASCVMRVERALKNVPGVQDVSVNLATESAR--IVAAPGDDIDVRVR 65

Query: 127 -AVQKAGYSASLPQSTKDDQSAVQRRLRNERLAVGAALLLALPLVLPMLVQPFGLHWMLP 185
            AV+ AGY      S  D+ +A+        +AVG  LLL++PL+ PM+  PFG  WMLP
Sbjct: 66  RAVRAAGYEPRAAASAADEAAALSPWHGFGPVAVG--LLLSIPLMAPMVGSPFGQDWMLP 123

Query: 186 AWAQFLLATPVQFILGARFYIAAWKAVRAGAGNMDLLVALGTSAGYGLSLYQWAQAPAGM 245
            W Q LLA PVQF LGARFY A W A +A  GNMDLLVALGTSA +GLSL+ W +A  G 
Sbjct: 124 PWVQLLLAAPVQFWLGARFYRAGWHAAKARTGNMDLLVALGTSAAFGLSLWLWWRAATGE 183

Query: 246 ------APHLYFEASAVVIALVLLGKYLESRAKRQTASAIRALEALRPERALRV-VDGVE 298
                  PHLYFEASAVVI LVLLGK+LE+RAKRQ  SAIRAL+ LRPE A  V   G E
Sbjct: 184 HAGHGEMPHLYFEASAVVITLVLLGKWLEARAKRQATSAIRALQQLRPEVAHLVGARGKE 243

Query: 299 EDVAIAHLRVGDLVLVKPGERFPVDGVVEDGSSHADEALISGESLPVPKQPGDSVTGGAI 358
            DV +A + VGD ++V+PGER P D  V +G S  DE++++GE LPVPK PGD++TGGA+
Sbjct: 244 SDVPLAEVMVGDHLVVRPGERVPADARVIEGQSEVDESMLTGEPLPVPKGPGDALTGGAV 303

Query: 359 NGEGRLLVRTQALGTETVLARIIRLVEDAQAAKAPIQKLVDRVSQVFVPAVLVLALITLI 418
           NG+GR+++   A+G E+VLARIIRLVEDAQAAKAPIQ+LVD+V+ VFVP VLV+A +TL 
Sbjct: 304 NGDGRMVIEVSAVGAESVLARIIRLVEDAQAAKAPIQRLVDKVAAVFVPVVLVIAFVTLA 363

Query: 419 GWWLAGVPLETALINAVAVLVIACPCALGLATPAAIMAGTGVAARHGILIKDAEALERAH 478
           GW +AG  +ETALI+AVAVLVIACPCALGLATP A+MAGTGVAA+HGILIKDA ALE AH
Sbjct: 364 GWLIAGAGIETALIHAVAVLVIACPCALGLATPVAVMAGTGVAAKHGILIKDARALEIAH 423

Query: 479 AVNRVVFDKTGTLTSGSPQVVHSQALDGNSA---DLYRLAGALQRGSEHPLAKAVLVACA 535
            V+ V FDKTGTLT G P +     + G  A    L  +A +LQ GSEHPLAKAVL A A
Sbjct: 424 RVDTVAFDKTGTLTLGRPVLTELLPVAGAIAAEDKLLAVAASLQGGSEHPLAKAVLAAAA 483

Query: 536 EQGLDVPTVADSQSLTGRGIAGRVEGRELALGNRRLLDESGLQPGELAAQAQAWEAEGRT 595
           ++ L  P ++  Q++ GRG+ G V+G   A+ + R   E    P   A   +  +A+G T
Sbjct: 484 QRNLQAPALSAMQAMPGRGVRGNVDGANWAIASLRWCRELDAMPD--ATDVERLQAKGAT 541

Query: 596 LSWL--IERGKQPRVVGLFAFGDSLKPGAAQAIETLHAQHISSHLLTGDNRGSANVVAEA 653
           +S L  ++      V  L AF D  KP AA+AI TL A+ +   +++GDN  +A  +A  
Sbjct: 542 VSALLRLDDAGSAHVQALLAFADEPKPQAAEAIRTLRARGLRVVMISGDNLRAAQAMAAR 601

Query: 654 LGI--DDVHAEVLPADKAATVAALKQEG-VVAMVGDGINDAPALAAADIGIAM---GGGT 707
           LGI  +DV A+VLPADKAA VAAL++ G VVAMVGDG NDAPALAAAD+GIAM   GGGT
Sbjct: 602 LGIAAEDVRADVLPADKAAQVAALRKNGHVVAMVGDGANDAPALAAADVGIAMAPSGGGT 661

Query: 708 DVAMQAAGITLMRGDPRLVPAALEISRKTYAKIRQNLFWAFIYNLIGIPLAALGYLNPVL 767
           DVAM+AAGITLMR D  LV  A E+S +T AKIRQNLFWAF YN+ GIPLAA G L+PV+
Sbjct: 662 DVAMEAAGITLMRVDLALVAQAFELSGRTVAKIRQNLFWAFAYNVAGIPLAAFGLLSPVV 721

Query: 768 AGAAMALSSVSVVSNALWLKTWKP 791
           AGAAMALSSVSV++NAL L+ WKP
Sbjct: 722 AGAAMALSSVSVMANALLLRRWKP 745



 Score = 67.4 bits (163), Expect = 3e-15
 Identities = 37/64 (57%), Positives = 43/64 (67%), Gaps = 2/64 (3%)

Query: 5  TTYDLPISGMTCASCAGRVERALRKVTGAEQVSVNLTTEKARVLAPPA-SLPALV-EAVR 62
          TT DL + GMTCASC  RVERAL+ V G + VSVNL TE AR++A P   +   V  AVR
Sbjct: 10 TTLDLSVGGMTCASCVMRVERALKNVPGVQDVSVNLATESARIVAAPGDDIDVRVRRAVR 69

Query: 63 EAGY 66
           AGY
Sbjct: 70 AAGY 73