Pairwise Alignments

Query, 1053 a.a., cation efflux system protein from Pseudomonas putida KT2440

Subject, 1045 a.a., CusA/CzcA family heavy metal efflux RND transporter from Rhodanobacter sp000427505 FW510-R12

 Score =  628 bits (1620), Expect = 0.0
 Identities = 367/1051 (34%), Positives = 583/1051 (55%), Gaps = 33/1051 (3%)

Query: 1    MFERIIRFAIEQRIVVMIAVLIMAGIGIYSYQKLPIDAVPDITNVQVQINTAAPGYSPLE 60
            M   +IR AI  R+ V++A L +A  G++S  + P+DA+PD+++ QV I T+  G SP  
Sbjct: 1    MIAALIRAAIANRVFVLLAALALAAAGVFSLTRTPLDALPDLSDTQVIIRTSWAGQSPQV 60

Query: 61   TEQRITFPVETAMAGLPGLQQTRSLSRSGLSQVTVIFKDGTDIFFARQLINERLQVAKEQ 120
             E +IT+P+ T M  +PG +  R+ S  G S V V+F D TD+++AR  + E L   ++Q
Sbjct: 61   VEDQITYPLATTMLSVPGAKTVRAYSFFGDSYVYVLFDDSTDLYWARSRVLEYLSQVRDQ 120

Query: 121  LPEGVEAVMGPVSTGLGEIFLWTVEAEDGAVKEDGTPYTPTDLRVIQDWIIKPQLRNVPG 180
            LP GV   +GP +TGLG ++ + +    G        +   +LR +QDW ++ QL+ VP 
Sbjct: 121  LPVGVNPSLGPDATGLGWVYEYALVDRTGK-------HDLGELRALQDWFLRYQLKTVPD 173

Query: 181  VAEINTIGGYAKQFLVAPDPKRLATYKLTLNDLVAALESNNANVGAGYIERNGEQLLIRA 240
            +AE+ ++GG  + + + PDP+ L    +T+  L  A+ + N   G   +E+   +L++R+
Sbjct: 174  IAEVASLGGMERAWQIVPDPRALTARGITVAQLTDAVRAANGAGGGSVVEQGEAELMVRS 233

Query: 241  PGQVGNIEDIANIVI-TSVDGAPIRISSVADVSIGKELRTGAATENGR-EVVLGTVFMLI 298
             G + + ED  N+ I T+ +G P+ +  VA V  G   R G    +G+ EVV G   +  
Sbjct: 234  EGYLRSREDFENVPISTNTNGVPVLLREVATVRRGPSFRRGIVELDGQGEVVGGVAVLRS 293

Query: 299  GENSRTVSQAVAAKLADINRTLPKGVVAVTVYDRTNLVEKAIATVKKNLVEGAILVIAIL 358
            G+N++   +AV AKL ++ R+LP GV  V  YDR+ L++ A+  +   L+E  ++V  + 
Sbjct: 294  GKNAKAAIEAVKAKLTELKRSLPAGVEIVPTYDRSQLIDAAVENLWGKLLEEFLVVALVC 353

Query: 359  FLFLGNIRAALITAMVIPLSMLFTFTGMFNNKVSANLMSLG--ALDFGIIVDGAVVIVEN 416
             LFLG++R+AL+  + +PL +L  F  +    VSANLMSLG  A+  G +VD AVV++EN
Sbjct: 354  VLFLGHLRSALVAVVSLPLGVLAAFIALHLQGVSANLMSLGGIAIAIGAMVDAAVVMIEN 413

Query: 417  AIRRLAHAQHKH-GRMLTKTERFHEVFAAAREARRPLIFGQLIIMVVYLPIFALTGVEGK 475
              + L H +  H G       R+  V  AA E    L    LII + ++P+FAL G EGK
Sbjct: 414  THKHLEHWRDAHDGGEPQGAVRWSVVVEAAAEVGPALFISLLIIALSFIPVFALQGQEGK 473

Query: 476  MFHPMAFTVVMALLGAMVLSVTFVPAAIAMFVTGKVKEEEGVVMRTARLR-YEPVLQWVL 534
            +F P+AFT   A+  A  L+VT VP  +   + G+++ E    +    +  Y P+L+ VL
Sbjct: 474  LFKPLAFTKTYAMAAAAGLAVTLVPVLMGYLIRGRIRPEHTNPLNRGLIALYRPILEAVL 533

Query: 535  GHRNIAFSAAVALVVLSGLLASRMGSEFIPSLSEGDFAMQAMRVPGTSLTQSVEMQQRLE 594
             H     + A  L++ + L  SR+GSEF+P++ EG        +PG S  ++ ++ Q  +
Sbjct: 534  HHPKTTLALAGLLLLTALLPLSRLGSEFMPAMDEGTLLYMPTALPGLSAGKASQLLQLTD 593

Query: 595  KAVIAQVPEVERMFARSGTAEIASDPMPPNASDAYIMLKPQDQWPNPKKPRDELIAEVQK 654
            + +I  VPEV+ +F ++G A  A+DP P    +  I  KP+DQW  P     ++ AE+ K
Sbjct: 594  R-MIKTVPEVDHVFGKAGRANTATDPAPLEMFETTITFKPKDQW-RPGMTMAKIKAELNK 651

Query: 655  AAAGVPGSNYELSQPIQLRFNELISGVRSDVAVKVFGDDMDVLNNTANKIAAALKAVPGS 714
            A   VPG       P++ R + L +G++S + +KV G D   L    ++I    + VPG 
Sbjct: 652  AVQ-VPGLTNLFVPPLRNRIDMLATGIKSPIGIKVLGPDPSTLQEVTDRIETVARQVPGV 710

Query: 715  SEVKVEQTSGLPVLTINIDREKAARYGLNIADVQNSIAIAVGGRQAGTLYEGDRRFDMVV 774
                 E+ +    + + I R  AARYGL    VQ  +A  VGG   G   EG  R+ +V+
Sbjct: 711  GSAIAERAASGRYVDVRIRRVDAARYGLTQQQVQQLVATVVGGDSIGQTVEGRERYPIVL 770

Query: 775  RLPETVRTDVAGMSSLLIPVPANAAQGANQIGFIPLSQVANLDLQLGPNQISRENGKRLV 834
            R P   R  +A +  L I V AN AQ       + L+QVA++ +  GP Q+  ENG+   
Sbjct: 771  RYPRAERDSLAALKVLPI-VAANGAQ-------LTLAQVADIKVVAGPPQLKSENGQLAS 822

Query: 835  IVSANVRGRDLGSFVEEATASLDKKVQIPAGYWTTWGGQFEQLQSAAKRLQIVVPVALLL 894
             +  +  GRDLG+ V +   ++ + V++P G    W GQFE L+ A +RL +VVPV LL+
Sbjct: 823  YLYVDTAGRDLGTVVADLQRAVARDVKLPPGITVAWSGQFEYLEQAMQRLTLVVPVVLLI 882

Query: 895  VMTLLFLMFNNLKDGMLVFTGIPFALTGGVVALWLRDIPLSISAGVGFIALSGVAVLNGL 954
            V  L++ +F  + +  L+   +P AL GG+  +WL    +SI+  +GFIAL+GVA   G+
Sbjct: 883  VFVLIYAVFRRMSEAALIMASVPLALVGGLWLIWLLGHAVSIATMIGFIALAGVAAEFGV 942

Query: 955  VMIAFIRGLREE---------GRTLRQAVDEGALTRLRPVLMTALVASLGFIPMALATGT 1005
            VM+ ++R   +             L +A+ EGA+ R+RP  MT  V   G  P+ L  G 
Sbjct: 943  VMMLYLRHAWDRQLAADPHSGPAELDEAIREGAVQRVRPKAMTVAVILAGLFPILLGHGA 1002

Query: 1006 GAEVQRPLATVVIGGILSSTALTLLVLPALY 1036
            G+EV + +A  +IGG+L++  L++LV+PA +
Sbjct: 1003 GSEVMQRIAAPMIGGMLTAPLLSMLVIPAAF 1033



 Score = 42.4 bits (98), Expect = 2e-07
 Identities = 74/369 (20%), Positives = 155/369 (42%), Gaps = 32/369 (8%)

Query: 160  PTDLRVIQDWIIKPQLRNVPGV----AEINTIGGYAKQFLVAPDPKRLATYKLTLNDLVA 215
            P+ L+ + D I +   R VPGV    AE    G Y    +   D  R    +  +  LVA
Sbjct: 690  PSTLQEVTDRI-ETVARQVPGVGSAIAERAASGRYVDVRIRRVDAARYGLTQQQVQQLVA 748

Query: 216  ALESNNANVGAGYIERNGEQLLIRAP-GQVGNIEDIANIVITSVDGAPIRISSVADVSI- 273
             +   ++ +G     R    +++R P  +  ++  +  + I + +GA + ++ VAD+ + 
Sbjct: 749  TVVGGDS-IGQTVEGRERYPIVLRYPRAERDSLAALKVLPIVAANGAQLTLAQVADIKVV 807

Query: 274  --GKELRTGAATENGREVVLGTVFMLIGENSRTVSQAVAAKLADINRT--LPKGVVAVTV 329
                +L++    ENG+       ++ +    R +   VA     + R   LP G+  V  
Sbjct: 808  AGPPQLKS----ENGQLAS----YLYVDTAGRDLGTVVADLQRAVARDVKLPPGIT-VAW 858

Query: 330  YDRTNLVEKAIATVKKNLVEGAILVIAILFLFLGNIRAALITAMVIPLSMLFTFTGMFNN 389
              +   +E+A+  +   +    ++V  +++     +  A +    +PL+++    G++  
Sbjct: 859  SGQFEYLEQAMQRLTLVVPVVLLIVFVLIYAVFRRMSEAALIMASVPLALV---GGLWLI 915

Query: 390  KVSANLMSLGALDFGIIVDGAVVIVENAIRRLAHAQHKHGRMLTKTERFH--EVFAAARE 447
             +  + +S+  +   I + G  V  E  +  + + +H   R L         E+  A RE
Sbjct: 916  WLLGHAVSIATMIGFIALAG--VAAEFGVVMMLYLRHAWDRQLAADPHSGPAELDEAIRE 973

Query: 448  AR----RPLIFGQLIIMVVYLPIFALTGVEGKMFHPMAFTVVMALLGAMVLSVTFVPAAI 503
                  RP      +I+    PI    G   ++   +A  ++  +L A +LS+  +PAA 
Sbjct: 974  GAVQRVRPKAMTVAVILAGLFPILLGHGAGSEVMQRIAAPMIGGMLTAPLLSMLVIPAAF 1033

Query: 504  AMFVTGKVK 512
             + V  +++
Sbjct: 1034 RVLVLRRLR 1042