Pairwise Alignments
Query, 1039 a.a., Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA from Hydrogenophaga sp. GW460-11-11-14-LB1
Subject, 1066 a.a., Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA from Hydrogenophaga sp. GW460-11-11-14-LB1
Score = 634 bits (1635), Expect = 0.0
Identities = 365/1054 (34%), Positives = 595/1054 (56%), Gaps = 33/1054 (3%)
Query: 1 MIARLIHWSIANRFLVLLATLMLSAWGLVAMQRTPLDALPDLSDTQVIIRTTWPGQAPQI 60
M R+I ++I R+LV+LA L + G+ QR +DA+PD+++ QV I T PG +P
Sbjct: 1 MFERIIRFAIEQRWLVMLAVLGMVGLGVYNFQRLSIDAVPDITNVQVQINTAAPGYSPLE 60
Query: 61 VENQVTYPLTTTMLSVPGTKAVRGFSMFGDSFVYVLFDDNVDLYWARSRVLEYLNQVQAR 120
E +VT+P+ T M +PG + R S +G S V V+F D D+Y+AR V E + +
Sbjct: 61 TEQRVTFPIETVMAGLPGLQQTRSISRYGISQVTVVFKDGTDIYFARQLVNERMQGAVSS 120
Query: 121 LPATARTSLGPDATGVGWIYQYALVDRTGQQDV-------AQLRALQDWFLRFELKTVPD 173
LP ++GP ++G+G I+ + + G ++ LR +QDW ++ +L+ VP
Sbjct: 121 LPEGVHPAVGPISSGLGEIFLWTVEAEEGAKNADGKPYTPTDLRVIQDWIIKPQLRNVPG 180
Query: 174 VAEVASVGGMVKQYQIVLDPDRLASYGITQKMVGEAVGRANQEAGGSVLELGEAEYAVRA 233
V E+ S+GG +Q+Q+ P+RL +YG+T V +A+ R N G +E +Y +RA
Sbjct: 181 VTEINSIGGFERQFQVAPIPERLLAYGLTLPDVVQALERNNANVGAGYIERRGEQYLIRA 240
Query: 234 SGYLKTLDDFRAIPLTTTPAGVSVRLGDVARVQTGPEMRRGIGELNGEGEAVGGVVVMRS 293
G + +L+D R + L +G VR+ DVA V G ++R G NG E V G V M
Sbjct: 241 PGQVGSLEDLRNVVLANN-SGTPVRIRDVAEVDIGQDLRTGAATDNGR-EVVLGTVFMLL 298
Query: 294 GKNALRTIEAVKAKLAELQRSLPAGVEIVPVYDRSGLIERAVKNLGVKLVEEFIVVALVC 353
G+N+ +AV K+ E+ ++LP GV + VYDR+ L+++A+ + L E ++V V
Sbjct: 299 GENSRTVAQAVAKKMEEINQNLPEGVHAITVYDRTVLVDKAISTVKKNLFEGAVLVIAVL 358
Query: 354 VAFLFHFRSALVASVSLPLGVLIAFGVMQQQGINANVMSLGGIAIAIGAMVDAAIVMIEN 413
FL + R+AL+ ++ +PL +L F M Q ++AN+MSLG A+ G +VD A+V++EN
Sbjct: 359 FLFLGNIRAALLTALVIPLSMLFTFTGMVNQKVSANLMSLG--ALDFGIIVDGAVVIVEN 416
Query: 414 AHKHLERWAHQHPGETLRGDAHWKVIATAAAEVGPALFFSLLIITLSFIPVFTLEAQEGR 473
+ L +H + + +V A A+ E L + LII + ++P+F L EG+
Sbjct: 417 CIRRLAHAQERHGRPLTKAERFHEVFA-ASQEARRPLLYGQLIIMVVYLPIFALTGVEGK 475
Query: 474 LFAPLAFTKTYAMAASAGLAVTLIPVLMGYLIRGRIPAETANPLNRALIALYRPVLDAVL 533
+F P+A T A+ + L++T IP + I + E N L Y P+L +
Sbjct: 476 MFHPMALTVVIALLGAMILSITFIPAAVAMFIGNNV-GEKENRLMGWARRAYHPLLKRAM 534
Query: 534 KAPRLTLVVAALVLVASLWPLQHIGSEFMPPLDEGDLLYMPTALPGLSASKAAELLQQTD 593
A + L AA+ ++ S +GSEF+P L+EGD +PG S S++ ++ QQ +
Sbjct: 535 GARAVVLTAAAVAVLLSGLLATRLGSEFIPSLNEGDFAIQALRIPGTSLSQSVQMQQQIE 594
Query: 594 R-LIKTVPEVQSVYGKAGRADTATDPAPLEMFETTIQFKPREQWRAGL-TPEALVEEL-D 650
R L+ PEV+ V+ + G A+ A+D P + + + KP +QW + T LVE + +
Sbjct: 595 RTLVAEFPEVERVFARTGTAEIASDLMPPNISDAYVMLKPEDQWPSPKRTRRELVEAVQE 654
Query: 651 RTVRVPGLSNIWVPPIRNRIDMLATGIKSPVGVKVAGADLATIDRLTRQIEQAVKDVPGV 710
R ++PG + + PI+ R + L +G+++ V VKV G D+ +++ ++I + + + G
Sbjct: 655 RVSKIPGNNYEFSQPIQLRFNELISGVRADVAVKVFGDDMDVLNKTAQEIAEVLGSINGA 714
Query: 711 SSALAERLTGGRYIDVDIRRADAARYGLNIADVQEIVAGSVGGMNIGETVEGLQRFPINL 770
S E+ TG + ++I R+ AARYG+N+ D+Q+ +A ++GG N G EG +RF I +
Sbjct: 715 SEVNVEQTTGLPMLSINIDRSKAARYGVNVGDIQDTIATAIGGRNAGTLFEGDRRFDIVV 774
Query: 771 RYPRELRDSLPKLRALPIVTPTGQR---------LVLSDVADLRISDGPPMLRSENARLA 821
R P +R L +R LP+ P + + LS++A L ++ GP + E+ +
Sbjct: 775 RLPERMRGDLESIRRLPVTLPAATQADGSTRVSFIPLSELATLDLAPGPNQVSREDGKRR 834
Query: 822 GFVYVDIRGRDLRGAVLDMQRAVATAVELPAGYSVSWSGQFEFLERATAKLQLVVPFTLL 881
V ++RGRDL V + A+ V +P GY +W GQFE L+ AT +LQ+VVP LL
Sbjct: 835 IVVSTNVRGRDLGSFVEEAGAALKEKVVIPTGYWTTWGGQFENLQSATKRLQIVVPVALL 894
Query: 882 IIFVLLYLIFRRFDEALLIMATLPFALVGGVWLLWLLGHHLSVASAVGFIALAGVAAEFG 941
++FVLL+ +F + L++ +PFAL GG+ LWL LS+++AVGFIAL+GVA G
Sbjct: 895 LVFVLLFAMFGNVRDGLIVFTGIPFALTGGILALWLRDIPLSISAAVGFIALSGVAVLNG 954
Query: 942 VIMLLYLKHAWRDRLDAGLDGDASLLDAIREGAVLRVRPKAMTVATIVAGLLPLFWGLGT 1001
++M+ ++++ +G A+L DAI EGA+ R+RP MT G +P+ GT
Sbjct: 955 LVMISFIRNL--------REGGATLDDAIFEGALTRLRPVLMTALVASLGFVPMAIATGT 1006
Query: 1002 GSEVMQRIAAPMVGGMISAPLLSLFVVPVAYRLM 1035
G+EV + +A ++GG++S+ L+L V+PV YRL+
Sbjct: 1007 GAEVQRPLATVVIGGILSSTALTLLVLPVLYRLV 1040
Score = 35.4 bits (80), Expect = 2e-05
Identities = 80/364 (21%), Positives = 141/364 (38%), Gaps = 46/364 (12%)
Query: 169 KTVPDVAEV-ASVGGM----------VKQYQIVLDPDRLASYGIT----QKMVGEAVGRA 213
KT ++AEV S+ G + I +D + A YG+ Q + A+G
Sbjct: 699 KTAQEIAEVLGSINGASEVNVEQTTGLPMLSINIDRSKAARYGVNVGDIQDTIATAIGGR 758
Query: 214 NQEAGGSVLELGEAEY--AVRASGYLK-TLDDFRAIPLT---TTPAGVSVR-----LGDV 262
N G++ E G+ + VR ++ L+ R +P+T T A S R L ++
Sbjct: 759 N---AGTLFE-GDRRFDIVVRLPERMRGDLESIRRLPVTLPAATQADGSTRVSFIPLSEL 814
Query: 263 ARVQTGPEMRRGIGELNGEGEAVGGVVVMRSGKNALRTIEAVKAKLAELQRSLPAGVEIV 322
A + P + + +G+ V V G++ +E A L E + +P G
Sbjct: 815 ATLDLAPGPNQ-VSREDGKRRIVVSTNVR--GRDLGSFVEEAGAALKE-KVVIPTGYWTT 870
Query: 323 PVYDRSGLIERAVKNLGVKLVEEFIVVALVCVAFLFHFRSALVASVSLPLGVLIAFGVMQ 382
L + A K L + + ++V ++ A + R L+ +P + +
Sbjct: 871 WGGQFENL-QSATKRLQIVVPVALLLVFVLLFAMFGNVRDGLIVFTGIPFALTGGILALW 929
Query: 383 QQGINANVMSLGGIAIAIGAMVDAAIVMIENAHKHLERWAHQHPGETLRGDAHWKVIATA 442
+ I ++ + G G V +VMI E G TL DA + A
Sbjct: 930 LRDIPLSISAAVGFIALSGVAVLNGLVMISFIRNLREG------GATL-DDA---IFEGA 979
Query: 443 AAEVGPALFFSLLIITLSFIPVFTLEAQEGRLFAPLAFTKTYAMAASAGLAVTLIPVLMG 502
+ P L + L+ +L F+P+ + PLA + +S L + ++PVL
Sbjct: 980 LTRLRPVLM-TALVASLGFVPMAIATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYR 1038
Query: 503 YLIR 506
+ R
Sbjct: 1039 LVYR 1042