Pairwise Alignments
Query, 1993 a.a., alpha-2-macroglobulin from Serratia liquefaciens MT49
Subject, 1653 a.a., hypothetical protein (NCBI) from Escherichia coli BW25113
Score = 285 bits (728), Expect = 5e-80
Identities = 368/1646 (22%), Positives = 673/1646 (40%), Gaps = 217/1646 (13%)
Query: 436 RFMLLEIDNQLVSNGGYKMPKKAYRVIEVPEFPKSLQFMSQGSLLSVNGDKQISVAARNV 495
R +++ I ++ + K + I + S+ F S+GSLL + + V A NV
Sbjct: 133 RDLIVTIGKEVKALNNATFSKDYEKTITTRDIQPSVGFASRGSLLPGKVVEGLPVMALNV 192
Query: 496 AGLRLDIKRVIPSQLQHIVSFKSREYSSAEFN-----RLDDEYFTEHFKYQTALNNDQPG 550
+ ++ RV P L +S S A + ++ D +T F A N +
Sbjct: 193 NNVDVNFFRVKPESLPAFISQWEYRNSLANWQSDKLLQMADLVYTGRFDLNPARNTREKL 252
Query: 551 VVNYQGIDLSRYLSTNPDSHRGVFLLTLSEWQPNRKPAEEEAGADESEEESGDQAGVGDS 610
++ I P GV+L +++ +G +
Sbjct: 253 LLPLGDI--------KPLQQAGVYLAVMNQ--------------------AGRYDYSNPA 284
Query: 611 RFVVVTDLGIVAKSSQDKTRDVFVQSIHSGAPVGSAKVSVIAKNGVTLLSQITDTNGHVR 670
++D+G+ A ++ D+F QS+ +GA +VS++ + G TL +D GHV+
Sbjct: 285 TLFTLSDIGVSAHRYHNRL-DIFTQSLENGAAQQGIEVSLLNEKGQTLTQATSDAQGHVQ 343
Query: 671 FPALDVYTNERQPVMFLVEKEGDVSFLPTGSYNDRGLDFSRFDIAGEQTPTDPRALSSYL 730
N++ + L K+G + L LD + F+IAG + ++
Sbjct: 344 LE------NDKNAALLLARKDGQTTLL---DLKLPALDLAEFNIAG----APGYSKQFFM 390
Query: 731 FSDRGVYRPGDTFNVGLITRAADWSVGLAGVPVRAEIRDPRDKLMTTVPLTLGASGFNEL 790
F R +YRPG+T + + R AD L P++ ++ P +++ +V ++ +G
Sbjct: 391 FGPRDLYRPGETVILNGLLRDADGKA-LPNQPIKLDVIKPDGQVLRSV-VSQPENGLYHF 448
Query: 791 SYTTDENSPTGEWNVYLYLVGKNHDTSTLLGHTSVNVKEFEPDQLKVKL--ELTPNRQQG 848
++ D N+ TG W++ + + +V++F P+++ + L E TP +
Sbjct: 449 TWPLDSNAATGMWHI------RANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKD 502
Query: 849 WVKPSELQAKIDVQNLFGTPAQDRRVTSRLTLRPMYPSFDRFPDYAFYENRQNSDGFETE 908
VK S + L+G PA + +L LRP+ + P + F + + +
Sbjct: 503 EVKFSVVG-----YYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLD 557
Query: 909 LEERTTDEQGAANIPLDLKGYADATYQLQLLSE-AFVAGGGRSVAATARALVSPYDYLVG 967
+ T D++G + + + + + LQ++ + + + GGR V A + P D L G
Sbjct: 558 EVQLTLDDKGRGEVSTESQ-WKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPG 616
Query: 968 VK----ADGDLGYINRDALRQ----------LNVIAVDPSLKQIALADLKLVLIEQKYIS 1013
++ + Y ++Q +++ D + A++ L++ LI ++
Sbjct: 617 IRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDY 676
Query: 1014 VLTKQDSGVYKYQSKMKEVTLSEQPLALSEQGNDLRLATDKPGDFVLVIE---DAQGKVL 1070
+ ++ Q K++ +EQ L L + G + L ++ +A V
Sbjct: 677 YWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVR 736
Query: 1071 NRVAYSVAGNANLSRSLDRNAELKLKLNQAEYQPGEEIEVSINAPYTGSGLITIEKDRVY 1130
YS N++ S ++ R + LKL++A Y+PG+ I++ I AP G G +E
Sbjct: 737 FWAGYSWQDNSDGSGAV-RPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGP 795
Query: 1131 AWQWFHSDTTSSVQKIRLPAGMEGNG---YINVQFVRDVNSSEIFMSPLSYGVMPFKIST 1187
W W D + + +P N Y++ VR + S + GV+ +
Sbjct: 796 LW-WQEIDVRAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGD 854
Query: 1188 RARQNGLEVTAPSVIKPGEDLTMTVKT-----DGPQQVALF--AVDEGILQVARYRLKDP 1240
R+ L + P+ ++P + LT+ +K + P+QV + AVD G+L + Y DP
Sbjct: 855 ENRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDP 914
Query: 1241 LEFFFSKRELSVTSSQILDLILPEFSKLMALTAAPGGDAGEGLDLNLNPFKRKRDKPVAY 1300
+ FF ++ I ++ +L AL GGD E KR PV +
Sbjct: 915 WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRF--GGDGDE--------LKRGGKPPVNH 964
Query: 1301 WSGITEV--------NGEKAFVYPVPDYFNGKIRVMAISVTPDKIGKAQTAATVRDNFIM 1352
+ + + GE + P+ D FNG++RVMA + T D G ++ V I
Sbjct: 965 VNIVVQQALPVTLNEQGEGSVTLPIGD-FNGELRVMAQAWTADDFGSNESKVIVAAPVIA 1023
Query: 1353 TPNVPAMVAPGDEFDVSVGVSNNLEGLNGQPVAVSVHLTPPPQLDVVGNAVQGLSLAEKR 1412
N+P +A GD +++ ++N L +P ++V LT L++V ++ + LA
Sbjct: 1024 ELNMPRFMASGDTSRLTLDITN----LTDKPQKLNVALTASGLLELVSDSPAAVELAPGV 1079
Query: 1413 EGVVNFRLRAKSALGDAPLVFDASYGDKSSRRTVSTS-------VRPAMPYRTQTVMGRM 1465
+ +RA GD + S G TV+ VRPA P +T +
Sbjct: 1080 RTTLFIPVRALPGYGDGEIQATIS-GLALPGETVADQHKQWKIGVRPAFPAQTVNYGTAL 1138
Query: 1466 SGGSQ---NVEGLRQMFDAYAQRQAAVSHSPLVLTNGLAQYLADYPYYCSEQIVSRSIPL 1522
G +GL+ + Q +S P + + L YPY C EQ S P
Sbjct: 1139 QPGETWAIPADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPS 1198
Query: 1523 ILQSRHPEMAGGLSQTEVSKQLRNL-LGVLR--SRQNDSGAIGAWRSSPDADPFVTPYVV 1579
+ + A G+ K+ ++ +G+ R Q D+G W + D + ++T YV+
Sbjct: 1199 LYTNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVM 1258
Query: 1580 QYLLEAKQAGYALPEGMLEEAN-GALRELAASGF------DDL--YRLRLRSWAIYLLTR 1630
+L+ A + GY++P + N LR L G D+L + ++S+A +L R
Sbjct: 1259 DFLVRAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLAR 1318
Query: 1631 QGEVTTNALAMVQDTLQKRYPDSWKTDLSTLYLASSYQLL---KMDDEAAALLQPSWQQL 1687
Q + AL + + + + L L L + + + +EA AL +
Sbjct: 1319 QQKAPLGALREIWE-----HRADAASGLPLLQLGVALKTMGDATRGEEAIALA----LKT 1369
Query: 1688 SKAYDSAWWTQNYFDPLVQDATRLYLITRHFPEKVASIPPQVLENMVKALKEERYTTYSS 1747
+ D W +Y L +A L L+ + K L +E+YT
Sbjct: 1370 PRNSDERIWLGDYGSSLRDNALMLSLLEEN-----------------KLLPDEQYT---- 1408
Query: 1748 AMSILALESYSAQVAQSANAGSLDITQIGKGGNAAPQRIAELQG------LFAKGQFTAD 1801
++ L+ +++ + + + +L + A + I +L G F+ Q T +
Sbjct: 1409 LLNTLSQQAFGERWLSTQESNALFL---------AARTIQDLPGKWQAQTSFSAEQLTGE 1459
Query: 1802 AA-----------AVRFTNSGDAPAWYSVTQAGYNLAAPQKALARGLEITRDY--TDEQG 1848
A ++ +NSGD P W + +GY +AP A L+I R TD +
Sbjct: 1460 KAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYPQSAPLPA-NNVLQIERHILGTDGKS 1518
Query: 1849 KPVTQVTLGQKVNVHLKIRANAKEGLSNLAIVDLLPGGFEVVQQTPPEPAADEDSEAEAP 1908
K + + G V V L+++A+ + + +VDLLP G E+ Q +A +
Sbjct: 1519 KSLDSLRSGDLVLVWLQVKAS--NSVPDALVVDLLPAGLELENQNLANGSASLEQ----- 1571
Query: 1909 SSGWQSPLAASGSSWAPDYSDIREDRVIIYGSASTDVQEF-----VYQIKATNTGSFIIP 1963
S G L + + + R+DR + A+ V E+ VY +A G++ +P
Sbjct: 1572 SGGEVQNLLNQMQQASIKHIEFRDDRFV----AAVAVDEYQPVTLVYLARAVTPGTYQVP 1627
Query: 1964 PAYGEAMYDREVQAMSVGSGKLVVVP 1989
E+MY + +A L+V P
Sbjct: 1628 QPMVESMYVPQWRATGAAEDLLIVRP 1653