Pairwise Alignments

Query, 893 a.a., pyruvate dehydrogenase E1 component, homodimeric type from Kangiella aquimarina DSM 16071

Subject, 887 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Escherichia coli ECOR38

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 576/888 (64%), Positives = 709/888 (79%), Gaps = 9/888 (1%)

Query: 7   NEAVQQDVDPIETQEWLDALDAVMAEEGVERAHYLLEKLVAKARRAGANLPFDLTTA-YL 65
           +E    DVDPIET++WL A+++V+ EEGVERA YL+++L+A+AR+ G N+      + Y+
Sbjct: 2   SERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNYI 61

Query: 66  NTIPPSQEAHMPGDQEMERRLRAIIRWNAIAIVLQASKKDLELGGHLSSFASSATLYDVG 125
           NTIP  ++   PG+ E+ERR+R+ IRWNAI  VL+ASKKDLELGGH++SF SSAT+YDV 
Sbjct: 62  NTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVC 121

Query: 126 FNHFFHGATDEHGGDLIYYQGHCSPGIYARAFLEGRLSEDQLANFRQEVDGKGLSSYPHP 185
           FNHFF    ++ GGDL+Y+QGH SPG+YARAFLEGRL+++QL NFRQEV G GLSSYPHP
Sbjct: 122 FNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPHP 181

Query: 186 WLMPEFWQFPTVSMGLGPIQAIYQARFLKYLEDRGLAKTKGRKVWAFLGDGEMDEPESMG 245
            LMPEFWQFPTVSMGLGPI AIYQA+FLKYLE RGL  T  + V+AFLGDGEMDEPES G
Sbjct: 182 KLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESKG 241

Query: 246 AIGLAGREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVLKVIWGRYWDP 305
           AI +A REKLDNL+FV+NCNLQRLDGPV GNGKII ELEG F GAGWNV+KV+WG  WD 
Sbjct: 242 AITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDE 301

Query: 306 LIARDTEGRLLKVMNETVDGEYQNCKAKGGAYTREHFFGKDPKLLEMVANMSDEDIWRLN 365
           L+ +DT G+L+++MNETVDG+YQ  K+K GAY REHFFGK P+   +VA+ +DE IW LN
Sbjct: 302 LLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALN 361

Query: 366 RGGHDPHKVYAAYHRAVNTEGQPTVILAKTVKGYGMGSSGEGKNISHQVKKMNLEALKHF 425
           RGGHDP K+YAA+ +A  T+G+ TVILA T+KGYGMG + EGKNI+HQVKKMN++ ++H 
Sbjct: 362 RGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRHI 421

Query: 426 RDRFNVPIPDDKLEEVPLYHPGEDSDEIKYLRERREKLGGYLPARRPQ-SDTLDIPALSA 484
           RDRFNVP+ D  +E++P     E S+E  YL  +R+KL GYLP+R+P  ++ L++P+L  
Sbjct: 422 RDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQD 481

Query: 485 FEPLLKATGDREISTTMAFVRALNILLKDKGLKERIVPIIPDEARTFGMEGLFRQIGIYS 544
           F  LL+    +EISTT+AFVRALN++LK+K +K+R+VPII DEARTFGMEGLFRQIGIYS
Sbjct: 482 FGALLEEQ-SKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS 540

Query: 545 SSGQLYEPVDSDQIMYYREDKKGQILEEGINEAGAMSSWMAAATSYSSNNLPMIPFYVYY 604
            +GQ Y P D +Q+ YY+ED+KGQIL+EGINE GA  SW+AAATSYS+NNLPMIPFY+YY
Sbjct: 541 PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYY 600

Query: 605 SMFGFQRIGDLAWAAGDMQARGFLIGATSGRTTLNGEGLQHQDGHSHMISATIPNCISYD 664
           SMFGFQRIGDL WAAGD QARGFLIG TSGRTTLNGEGLQH+DGHSH+ S TIPNCISYD
Sbjct: 601 SMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD 660

Query: 665 PTYAHEVAVIIREGLRRMYRD-QENVFYYITTLNENYPHPDMPEGSEEGIIKGMYLLHDN 723
           P YA+EVAVI+ +GL RMY + QENV+YYITTLNENY  P MPEG+EEGI KG+Y L   
Sbjct: 661 PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI 720

Query: 724 KSRKKAPRVQLMGSGAILREVEYAAELLEKDFGVLSDIWSVTSFTELRREGLAVERENML 783
           +  K   +VQL+GSG+ILR V  AAE+L K++GV SD++SVTSFTEL R+G   ER NML
Sbjct: 721 EGSK--GKVQLLGSGSILRHVREAAEILAKEYGVGSDVYSVTSFTELARDGQDCERWNML 778

Query: 784 NPTKKPKQTYVEQCLAKQKGPVIAATDYMKSYADQIRNFVP-QRYTVLGTDGFGRSDSRE 842
           +P + P+  Y+ Q +     P +A+TDYMK +A+Q+R +VP   Y VLGTDGFGRSDSRE
Sbjct: 779 HPLETPRVPYIAQVM--NDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRE 836

Query: 843 NLRRFFEVDRYYIVLAALKTLADEGEIDVKEVTKAIKRYNIDTDKADP 890
           NLR  FEVD  Y+V+AAL  LA  GEID K V  AI ++NID DK +P
Sbjct: 837 NLRHHFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNP 884