Pairwise Alignments

Query, 606 a.a., DNA mismatch repair protein MutL from Agrobacterium fabrum C58

Subject, 642 a.a., DNA mismatch repair endonuclease MutL from Dickeya dianthicola ME23

 Score =  253 bits (645), Expect = 2e-71
 Identities = 193/578 (33%), Positives = 280/578 (48%), Gaps = 48/578 (8%)

Query: 1   MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNG 60
           M I+ L   L NQIAAGEV+ERP+S  KELVEN++DAGATRI+I    GG  L+RI DNG
Sbjct: 1   MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIEIERGGAKLIRIRDNG 60

Query: 61  SGMSPADLELAVRRHCTSKISTTLDDIR---TLGFRGEALPSIGSVAKLTITSRQQGAEQ 117
            G+  A+L LA+ RH TSKI+ TLDD+    +LGFRGEAL SI SV++L +TSR     +
Sbjct: 61  CGIGKAELALALARHATSKIA-TLDDLEAIVSLGFRGEALASISSVSRLILTSRTDAQVE 119

Query: 118 GSVISVTGGKVS-DVRPAASNAGTIVEVRDLFFATPARLKFLKTERAEAAAITEVVKRMA 176
                  G +++  V+PAA   GT +EV DLF+ TPAR KFL+TE+ E   I EVV+R+A
Sbjct: 120 AWQAYAEGREMAVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFMHIDEVVRRIA 179

Query: 177 IAFPHIRFVLSGTDRSTLEIPSTGD--DHLARMAQILGAEFKDNAIEIDAGREDVTLTGF 234
           +A   +   L    + T +  +  +      R+  I GA F  +A+ +     D+ + G+
Sbjct: 180 LARFDVAITLHHNGKLTRQYRAVSEPAQRERRLGSICGAAFLQHALAVSWQHGDLKIHGW 239

Query: 235 AGVPTFNRGNSSHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSITLDPAFVD 294
              PT +R     QY +VN R ++D+L+  AIR AY + +   + P  VL + +DP  VD
Sbjct: 240 VADPTGSRQLPEMQYCYVNQRMMRDRLINHAIRQAYQDQLRDEQQPAYVLYLEVDPHQVD 299

Query: 295 VNVHPAKSDVRFRDPGLIRGLIVGAIRQALTR----------DGDRAAT----TGASQMM 340
           VNVHPAK +VRF    L+   I  A+   L +          D + AAT      A+   
Sbjct: 300 VNVHPAKHEVRFHQARLVHDFIYQAVMTVLQQAASPGLTGVGDTETAATWQPENRAAAGE 359

Query: 341 NAFRPGYSPSGLRPSPSATWSAATSPSRPLAVSGDMQFAEAA--QSRFSDI--------- 389
           N F     P+    S +++ S A+ P R  A      + EAA  Q +  ++         
Sbjct: 360 NQFARPAEPAPETASAASSGSTASHPGRH-ARERQPAYTEAAGYQKKQGELYQQLLHTES 418

Query: 390 --------------TMPTARAEPREAYEASQSPSPEPVLYPLGAARAQLHENYIIAQTEN 435
                           P AR +  E   A      E     LG        +Y + + + 
Sbjct: 419 SRQQTVAREAPPVKNTPAARHDVTEKAVAVGDAPLESHALGLGRVLTVYPPSYALVEYQQ 478

Query: 436 GLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDLPEEDCDRLMDHAAGFDALG 495
           GL ++    A   L   ++           Q LLIP+ + L   +   +         LG
Sbjct: 479 GLAVLSLTVAERYLRQAQLTPLEAGEGLRPQPLLIPQRLTLNPSELAVMQQQQPLLTRLG 538

Query: 496 LVIERFGPGAIAVRETPAMLGEVNVQGLVRQLADEIAE 533
           + +E   P    +R  P  L + N+Q L+  L   +A+
Sbjct: 539 IEVE-LAPPRATLRAVPLPLRQQNLQNLISDLLGYLAD 575