SEED Subsystems in Variovorax sp. SCN45

Subsystems are shown if they have at least one gene assigned to them. Because many roles are assigned to more than one subsystem, the subsystem may not be present even if the gene annotation(s) are correct.

Category Subsystem #Genes
Amino Acids and Derivatives L-2-amino-thiazoline-4-carboxylic acid-Lcysteine conversion 3
Amino Acids and Derivatives : Alanine, serine, and glycine Alanine biosynthesis 7
  Glycine Biosynthesis 3
  Glycine and Serine Utilization 23
  Glycine cleavage system 5
  Serine Biosynthesis 15
Amino Acids and Derivatives : Arginine; urea cycle, polyamines Arginine Biosynthesis extended 15
  Arginine Deiminase Pathway 3
  Arginine and Ornithine Degradation 15
  Cyanophycin Metabolism 2
  Polyamine Metabolism 17
  Urea decomposition 23
Amino Acids and Derivatives : Aromatic amino acids and derivatives Aromatic amino acid degradation 23
  Aromatic amino acid interconversions with aryl acids 11
  Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. 6
  Chorismate Synthesis 16
  Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) 13
  Phenylalanine and Tyrosine Branches from Chorismate 4
  Tryptophan synthesis 8
Amino Acids and Derivatives : Branched-chain amino acids Branched-Chain Amino Acid Biosynthesis 39
  HMG CoA Synthesis 18
  Isoleucine degradation 69
  Ketoisovalerate oxidoreductase 6
  Leucine Biosynthesis 13
  Leucine Degradation and HMG-CoA Metabolism 26
  Valine degradation 69
Amino Acids and Derivatives : Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Glutamate dehydrogenases 1
  Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis 51
  Glutamine synthetases 1
Amino Acids and Derivatives : Histidine Metabolism Histidine Biosynthesis 13
  Histidine Degradation 9
Amino Acids and Derivatives : Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis 24
  Lysine Biosynthesis DAP Pathway 12
  Lysine degradation 3
  Methionine Biosynthesis 40
  Methionine Degradation 18
  Methionine Salvage 2
  Threonine anaerobic catabolism gene cluster 4
  Threonine and Homoserine Biosynthesis 35
  Threonine degradation 13
Amino Acids and Derivatives : Proline and 4-hydroxyproline Proline, 4-hydroxyproline uptake and utilization 16
  Proline Synthesis 4
Carbohydrates Lacto-N-Biose I and Galacto-N-Biose Metabolic Pathway 9
Carbohydrates : Aminosugars Chitin and N-acetylglucosamine utilization 6
  N-Acetyl-Galactosamine and Galactosamine Utilization 4
Carbohydrates : CO2 fixation CO2 uptake, carboxysome 1
  Calvin-Benson cycle 13
  Carboxysome 3
  Photorespiration (oxidative C2 cycle) 26
Carbohydrates : Central carbohydrate metabolism Entner-Doudoroff Pathway 35
  Glycolate, glyoxylate interconversions 12
  Glycolysis and Gluconeogenesis 19
  Glycolysis and Gluconeogenesis, including Archaeal enzymes 15
  Methylglyoxal Metabolism 21
  Pentose phosphate pathway 13
  Pyruvate Alanine Serine Interconversions 13
  Pyruvate metabolism I: anaplerotic reactions, PEP 14
  Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate 39
  TCA Cycle 25
Carbohydrates : Di- and oligosaccharides Beta-Glucoside Metabolism 1
  Fructooligosaccharides(FOS) and Raffinose Utilization 1
  Lactose and Galactose Uptake and Utilization 11
  Lactose utilization 1
  Maltose and Maltodextrin Utilization 12
  Sucrose utilization 1
  Sucrose utilization Shewanella 1
  Trehalose Biosynthesis 15
  Trehalose Uptake and Utilization 2
Carbohydrates : Fermentation Acetoin, butanediol metabolism 7
  Acetyl-CoA fermentation to Butyrate 75
  Butanol Biosynthesis 57
  Fermentations: Lactate 2
  Fermentations: Mixed acid 12
Carbohydrates : Glycoside hydrolases Predicted carbohydrate hydrolases 2
Carbohydrates : Monosaccharides 2-Ketogluconate Utilization 3
  D-Galacturonate and D-Glucuronate Utilization 9
  D-Tagatose and Galactitol Utilization 1
  D-galactarate, D-glucarate and D-glycerate catabolism 10
  D-galactonate catabolism 3
  D-gluconate and ketogluconates metabolism 12
  D-ribose utilization 16
  Deoxyribose and Deoxynucleoside Catabolism 9
  Fructose utilization 8
  L-Arabinose utilization 14
  L-fucose utilization 1
  L-fucose utilization temp 3
  L-rhamnose utilization 4
  Mannose Metabolism 4
  Xylose utilization 9
Carbohydrates : One-carbon Metabolism One-carbon metabolism by tetrahydropterines 6
  Serine-glyoxylate cycle 43
Carbohydrates : Organic acids Isobutyryl-CoA to Propionyl-CoA Module 27
  Lactate utilization 4
  Methylcitrate cycle 7
  Propionate-CoA to Succinate Module 8
  Propionyl-CoA to Succinyl-CoA Module 4
  Tricarballylate Utilization 4
Carbohydrates : Polysaccharides Glycogen metabolism 8
Carbohydrates : Sugar alcohols Di-Inositol-Phosphate biosynthesis 1
  Erythritol utilization 1
  Ethanolamine utilization 4
  Glycerol and Glycerol-3-phosphate Uptake and Utilization 18
  Inositol catabolism 2
  Mannitol Utilization 4
  Propanediol utilization 2
  Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization 19
Cell Division and Cell Cycle Bacterial Cytoskeleton 31
  Control of cell elongation - division cycle in Bacilli 1
  Cyanobacterial Circadian Clock 1
  Macromolecular synthesis operon 6
  Two cell division clusters relating to chromosome partitioning 16
Cell Wall and Capsule Peptidoglycan Biosynthesis 33
  UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis 6
  YjeE 1
Cell Wall and Capsule : Capsular and extracellular polysacchrides Alginate metabolism 4
  Capsular heptose biosynthesis 4
  Colanic acid biosynthesis 5
  O-Methyl Phosphoramidate Capsule Modification in Campylobacter 1
  Polysaccharide deacetylases 2
  Rhamnose containing glycans 18
  Sialic Acid Metabolism 7
  dTDP-rhamnose synthesis 10
Cell Wall and Capsule : Cell wall of Mycobacteria linker unit-arabinogalactan synthesis 16
  mycolic acid synthesis 52
Cell Wall and Capsule : Gram-Negative cell wall components KDO2-Lipid A biosynthesis 13
  LOS core oligosaccharide biosynthesis 1
  Lipid A-Ara4N pathway ( Polymyxin resistance ) 2
  Lipid A modifications 6
  Lipopolysaccharide-related cluster in Alphaproteobacteria 1
Cell Wall and Capsule : Gram-Positive cell wall components Teichoic and lipoteichoic acids biosynthesis 3
  Teichuronic acid biosynthesis 1
Clustering-based subsystems Bacterial Cell Division 35
  Bacterial RNA-metabolizing Zn-dependent hydrolases 8
  CBSS-562.2.peg.5158 SK3 including 1
  Conserved gene cluster associated with Met-tRNA formyltransferase 18
  LMPTP YfkJ cluster 4
  LMPTP YwlE cluster 6
  NusA-TFII Cluster 8
  PA0057 cluster 3
  Putative hemin transporter 2
  Putative sulfate assimilation cluster 5
Clustering-based subsystems : Clustering-based subsystems CBSS-262719.3.peg.410 3
  Conenzyme B12 related Hypothetical: Clusters with cobST 2
Clustering-based subsystems : Lysine, threonine, methionine, and cysteine YeiH 3
Clustering-based subsystems : proteosome related Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related 2
Cofactors, Vitamins, Prosthetic Groups, Pigments Thiamin biosynthesis 37
Cofactors, Vitamins, Prosthetic Groups, Pigments : Biotin Biotin biosynthesis 20
Cofactors, Vitamins, Prosthetic Groups, Pigments : Coenzyme A Coenzyme A Biosynthesis 14
Cofactors, Vitamins, Prosthetic Groups, Pigments : Folate and pterines Folate Biosynthesis 28
  Molybdenum cofactor biosynthesis 20
  Pterin biosynthesis 4
  p-Aminobenzoyl-Glutamate Utilization 3
Cofactors, Vitamins, Prosthetic Groups, Pigments : Lipoic acid Lipoic acid metabolism 3
Cofactors, Vitamins, Prosthetic Groups, Pigments : NAD and NADP NAD and NADP cofactor biosynthesis global 26
  NAD regulation 14
  PnuC-like transporters 1
Cofactors, Vitamins, Prosthetic Groups, Pigments : Pyridoxine Pyridoxin (Vitamin B6) Biosynthesis 20
Cofactors, Vitamins, Prosthetic Groups, Pigments : Quinone cofactors Menaquinone Biosynthesis via Futalosine 2
  Menaquinone and Phylloquinone Biosynthesis 4
  Plastoquinone Biosynthesis 3
  Tocopherol Biosynthesis 3
  Ubiquinone Biosynthesis 10
Cofactors, Vitamins, Prosthetic Groups, Pigments : Riboflavin, FMN, FAD Riboflavin, FMN and FAD metabolism 4
Cofactors, Vitamins, Prosthetic Groups, Pigments : Tetrapyrroles Cobalamin synthesis 8
  Coenzyme B12 biosynthesis 25
  Experimental tye 15
  Heme and Siroheme Biosynthesis 15
DNA Metabolism DNA structural proteins, bacterial 7
  Restriction-Modification System 1
  YcfH 3
DNA Metabolism : DNA recombination RuvABC plus a hypothetical 3
DNA Metabolism : DNA repair 2-phosphoglycolate salvage 5
  DNA Repair Base Excision 17
  DNA repair, UvrABC system 5
  DNA repair, bacterial 26
  DNA repair, bacterial DinG and relatives 2
  DNA repair, bacterial MutL-MutS system 2
  DNA repair, bacterial RecFOR pathway 7
  DNA repair, bacterial UvrD and related helicases 5
DNA Metabolism : DNA replication DNA-replication 29
  DNA replication, archaeal 1
  DNA topoisomerases, Type I, ATP-independent 3
  DNA topoisomerases, Type II, ATP-dependent 4
  Plasmid replication 7
Fatty Acids, Lipids, and Isoprenoids Polyhydroxybutyrate metabolism 61
Fatty Acids, Lipids, and Isoprenoids : Fatty acids Fatty Acid Biosynthesis FASII 66
Fatty Acids, Lipids, and Isoprenoids : Isoprenoids Archaeal lipids 4
  Carotenoids 4
  Isoprenoid Biosynthesis 12
  Polyprenyl Diphosphate Biosynthesis 1
  polyprenyl synthesis 6
Fatty Acids, Lipids, and Isoprenoids : Phospholipids Glycerolipid and Glycerophospholipid Metabolism in Bacteria 58
Fatty Acids, Lipids, and Isoprenoids : Triacylglycerols Triacylglycerol metabolism 2
Iron acquisition and metabolism Campylobacter Iron Metabolism 19
  Heme, hemin uptake and utilization systems in GramPositives 2
  Hemin transport system 12
  Iron acquisition in Vibrio 33
  Transport of Iron 31
Iron acquisition and metabolism : Siderophores Siderophore Pyoverdine 12
Membrane Transport Choline Transport 2
  ECF class transporters 6
  Ton and Tol transport systems 37
  Transport of Manganese 2
  Transport of Molybdenum 6
  Transport of Nickel and Cobalt 3
  Transport of Zinc 5
Membrane Transport : ABC transporters ABC transporter alkylphosphonate (TC 3.A.1.9.1) 13
  ABC transporter branched-chain amino acid (TC 3.A.1.4.1) 105
  ABC transporter dipeptide (TC 3.A.1.5.2) 38
  ABC transporter oligopeptide (TC 3.A.1.5.1) 27
Membrane Transport : Protein and nucleoprotein secretion system, Type IV Type IV pilus 27
  pVir Plasmid of Campylobacter 5
Membrane Transport : Protein secretion system, Type II Widespread colonization island 8
Membrane Transport : Protein translocation across cytoplasmic membrane Twin-arginine translocation system 3
Membrane Transport : Sugar Phosphotransferase Systems, PTS Fructose and Mannose Inducible PTS 2
Membrane Transport : Uni- Sym- and Antiporters Sodium Hydrogen Antiporter 5
Metabolism of Aromatic Compounds Aromatic Amin Catabolism 5
  Benzoate transport and degradation cluster 21
  Gentisare degradation 8
  carbazol degradation cluster 1
Metabolism of Aromatic Compounds : Metabolism of central aromatic intermediates 4-Hydroxyphenylacetic acid catabolic pathway 16
  Catechol branch of beta-ketoadipate pathway 13
  Central meta-cleavage pathway of aromatic compound degradation 14
  Homogentisate pathway of aromatic compound degradation 31
  N-heterocyclic aromatic compound degradation 4
  Protocatechuate branch of beta-ketoadipate pathway 19
  Salicylate and gentisate catabolism 21
Metabolism of Aromatic Compounds : Peripheral pathways for catabolism of aromatic compounds Benzoate degradation 6
  Biphenyl Degradation 4
  Chloroaromatic degradation pathway 7
  Naphtalene and antracene degradation 4
  Phenylpropanoid compound degradation 13
  Quinate degradation 4
  Salicylate ester degradation 9
  n-Phenylalkanoic acid degradation 43
  p-Hydroxybenzoate degradation 2
Miscellaneous Muconate lactonizing enzyme family 2
  YaaA 1
  YbbK 4
  ZZ gjo need homes 18
Miscellaneous : Plant-Prokaryote DOE project Conserved gene cluster possibly involved in RNA metabolism 3
Motility and Chemotaxis Bacterial Chemotaxis 37
Motility and Chemotaxis : Flagellar motility in Prokaryota Flagellar motility 29
  Flagellum 60
  Flagellum in Campylobacter 9
Nitrogen Metabolism Allantoin Utilization 5
  Ammonia assimilation 21
  Cyanate hydrolysis 4
  Denitrification 2
  Dissimilatory nitrite reductase 1
  Nitrate and nitrite ammonification 10
  Nitric oxide synthase 1
Nucleosides and Nucleotides Hydantoin metabolism 19
  Ribonucleotide reduction 4
Nucleosides and Nucleotides : Detoxification Nudix proteins (nucleoside triphosphate hydrolases) 8
Nucleosides and Nucleotides : Purines De Novo Purine Biosynthesis 17
  Purine Utilization 11
  Purine conversions 29
Nucleosides and Nucleotides : Pyrimidines De Novo Pyrimidine Synthesis 16
  Pyrimidine utilization 17
Phages, Prophages, Transposable elements, Plasmids : Pathogenicity islands Staphylococcal pathogenicity islands SaPI 8
Phages, Prophages, Transposable elements, Plasmids : Transposable elements Tn552 5
Phosphorus Metabolism Alkylphosphonate utilization 13
  High affinity phosphate transporter and control of PHO regulon 11
  Phosphate metabolism 39
  Phosphonate metabolism 4
Potassium metabolism Glutathione-regulated potassium-efflux system and associated functions 4
  Potassium homeostasis 18
Protein Metabolism : Protein biosynthesis Ribosome LSU bacterial 32
  Ribosome SSU bacterial 23
  Ribosome activity modulation 1
  Ribosome biogenesis bacterial 13
  Trans-translation by stalled ribosomes 1
  Translation elongation factor G family 3
  Translation elongation factors eukaryotic and archaeal 1
  Translation initiation factors eukaryotic and archaeal 7
  Universal GTPases 23
  tRNA aminoacylation, Glu and Gln 2
Protein Metabolism : Protein degradation Proteasome bacterial 9
  Protein degradation 4
  Proteolysis in bacteria, ATP-dependent 20
  Putative TldE-TldD proteolytic complex 1
Protein Metabolism : Protein folding GroEL GroES 2
  Peptidyl-prolyl cis-trans isomerase 4
  Periplasmic disulfide interchange 6
  Protein chaperones 15
Protein Metabolism : Protein processing and modification N-linked Glycosylation in Bacteria 9
  Ribosomal protein S12p Asp methylthiotransferase 4
  Ribosomal protein S5p acylation 3
  Signal peptidase 3
Protein Metabolism : Selenoproteins Glycine reductase, sarcosine reductase and betaine reductase 6
  Selenocysteine metabolism 4
RNA Metabolism : RNA processing and modification ATP-dependent RNA helicases, bacterial 5
  Polyadenylation bacterial 4
  Queuosine-Archaeosine Biosynthesis 34
  RNA 3'-terminal phosphate cyclase 3
  RNA processing and degradation, bacterial 7
  Ribonuclease H 2
  Wyeosine-MimG Biosynthesis 6
  tRNA nucleotidyltransferase 1
  tRNA processing 12
  tRNA splicing 1
RNA Metabolism : Transcription RNA polymerase bacterial 4
  Rrf2 family transcriptional regulators 5
  Transcription factors bacterial 7
  Transcription factors cyanobacterial RpoD-like sigma factors 1
  Transcription initiation, bacterial sigma factors 14
Regulation and Cell signaling DNA-binding regulatory proteins, strays 18
  Orphan regulatory proteins 22
  Oxygen and light sensor PpaA-PpsR 2
  Sex pheromones in Enterococcus faecalis and other Firmicutes 10
  Stringent Response, (p)ppGpp metabolism 3
  Two-component regulatory systems in Campylobacter 6
  cAMP signaling in bacteria 21
Regulation and Cell signaling : Programmed Cell Death and Toxin-antitoxin Systems Murein hydrolase regulation and cell death 6
Regulation and Cell signaling : Quorum sensing and biofilm formation Autoinducer 2 (AI-2) transport and processing (lsrACDBFGE operon) 1
  Quorum Sensing: Autoinducer-2 Synthesis 1
Respiration Biogenesis of c-type cytochromes 8
  Biogenesis of cbb3-type cytochrome c oxidases 3
  Biogenesis of cytochrome c oxidases 13
  Carbon monoxide dehydrogenase maturation factors 5
  Formate hydrogenase 9
  Soluble cytochromes and functionally related electron carriers 20
Respiration : ATP synthases F0F1-type ATP synthase 6
Respiration : Electron accepting reactions Anaerobic respiratory reductases 32
  Terminal cytochrome C oxidases 11
  Terminal cytochrome O ubiquinol oxidase 4
  Terminal cytochrome d ubiquinol oxidases 5
  Terminal cytochrome oxidases 9
  Ubiquinone Menaquinone-cytochrome c reductase complexes 3
Respiration : Electron donating reactions CO Dehydrogenase 8
  Formate dehydrogenase 2
  Hydrogenases 1
  Membrane-bound Ni, Fe-hydrogenase 1
  Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes 1
  Respiratory Complex I 17
  Respiratory dehydrogenases 1 13
  Succinate dehydrogenase 7
Secondary Metabolism : Aromatic amino acids and derivatives Cinnamic Acid Degradation 2
Secondary Metabolism : Plant Hormones Auxin biosynthesis 4
  Auxin degradation 1
Stress Response Bacterial hemoglobins 15
  Hfl operon 5
  SigmaB stress responce regulation 4
  Universal stress protein family 2
Stress Response : Detoxification Glutathione-dependent pathway of formaldehyde detoxification 2
Stress Response : Heat shock Heat shock dnaK gene cluster extended 19
Stress Response : Osmotic stress Choline and Betaine Uptake and Betaine Biosynthesis 17
  Ectoine biosynthesis and regulation 1
Stress Response : Oxidative stress Glutaredoxins 2
  Glutathione: Biosynthesis and gamma-glutamyl cycle 8
  Glutathione: Non-redox reactions 24
  Glutathione: Redox cycle 2
  Oxidative stress 33
  Redox-dependent regulation of nucleus processes 6
  Rubrerythrin 3
Sulfur Metabolism Galactosylceramide and Sulfatide metabolism 1
  Sulfur oxidation 1
  Thioredoxin-disulfide reductase 12
Sulfur Metabolism : Organic sulfur assimilation Alkanesulfonate assimilation 43
  Alkanesulfonates Utilization 18
  Taurine Utilization 10
  Utilization of glutathione as a sulphur source 6
Virulence : Type III, Type IV, Type VI, ESAT secretion systems Type 4 secretion and conjugative transfer 32
Virulence, Disease and Defense : Adhesion Streptococcus pyogenes recombinatorial zone 1
Virulence, Disease and Defense : Detection MLST 5
Virulence, Disease and Defense : Invasion and intracellular resistance Cytolysin and Lipase operon in Vibrio 1
  Listeria surface proteins: Internalin-like proteins 1
Virulence, Disease and Defense : Resistance to antibiotics and toxic compounds Arsenic resistance 11
  Beta-lactamase 7
  Cobalt-zinc-cadmium resistance 41
  Copper homeostasis 18
  Copper homeostasis: copper tolerance 4
  Mercury resistance operon 2
  Methicillin resistance in Staphylococci 6
  Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria 9
  Multidrug Resistance Efflux Pumps 34
  Multidrug efflux pump in Campylobacter jejuni (CmeABC operon) 15
  Resistance to fluoroquinolones 4
  Zinc resistance 1