SEED Subsystems in Pseudomonas putida KT2440

Subsystems are shown if they have at least one gene assigned to them. Because many roles are assigned to more than one subsystem, the subsystem may not be present even if the gene annotation(s) are correct.

Category Subsystem #Genes
Amino Acids and Derivatives L-2-amino-thiazoline-4-carboxylic acid-Lcysteine conversion 1
Amino Acids and Derivatives : Alanine, serine, and glycine Alanine biosynthesis 8
  Glycine Biosynthesis 3
  Glycine and Serine Utilization 35
  Glycine cleavage system 8
  Serine Biosynthesis 14
Amino Acids and Derivatives : Arginine; urea cycle, polyamines Arginine Biosynthesis extended 15
  Arginine Deiminase Pathway 7
  Arginine and Ornithine Degradation 34
  Cyanophycin Metabolism 2
  Polyamine Metabolism 34
  Urea decomposition 13
Amino Acids and Derivatives : Aromatic amino acids and derivatives Aromatic amino acid degradation 7
  Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. 10
  Chorismate Synthesis 17
  Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) 15
  Phenylalanine and Tyrosine Branches from Chorismate 3
  Tryptophan synthesis 9
Amino Acids and Derivatives : Branched-chain amino acids Branched-Chain Amino Acid Biosynthesis 21
  HMG CoA Synthesis 8
  Isoleucine degradation 20
  Ketoisovalerate oxidoreductase 2
  Leucine Biosynthesis 5
  Leucine Degradation and HMG-CoA Metabolism 17
  Valine degradation 23
Amino Acids and Derivatives : Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Glutamate dehydrogenases 2
  Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis 40
  Glutamine synthetases 1
Amino Acids and Derivatives : Histidine Metabolism Histidine Biosynthesis 11
  Histidine Degradation 8
Amino Acids and Derivatives : Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis 25
  Lysine Biosynthesis DAP Pathway 12
  Lysine degradation 17
  Methionine Biosynthesis 38
  Methionine Degradation 14
  Methionine Salvage 3
  Threonine anaerobic catabolism gene cluster 4
  Threonine and Homoserine Biosynthesis 21
  Threonine degradation 6
Amino Acids and Derivatives : Proline and 4-hydroxyproline Proline, 4-hydroxyproline uptake and utilization 22
  Proline Synthesis 5
Carbohydrates Lacto-N-Biose I and Galacto-N-Biose Metabolic Pathway 5
  Unknown sugar utilization (cluster yphABCDEFG) 1
Carbohydrates : CO2 fixation Calvin-Benson cycle 11
  Carboxysome 3
  Photorespiration (oxidative C2 cycle) 29
Carbohydrates : Central carbohydrate metabolism Entner-Doudoroff Pathway 27
  Glycolate, glyoxylate interconversions 10
  Glycolysis and Gluconeogenesis 15
  Glycolysis and Gluconeogenesis, including Archaeal enzymes 10
  Methylglyoxal Metabolism 14
  Pentose phosphate pathway 12
  Pyruvate Alanine Serine Interconversions 15
  Pyruvate metabolism I: anaplerotic reactions, PEP 5
  Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate 24
  TCA Cycle 18
Carbohydrates : Di- and oligosaccharides Beta-Glucoside Metabolism 1
  Lactose and Galactose Uptake and Utilization 5
  Maltose and Maltodextrin Utilization 6
  Trehalose Biosynthesis 7
Carbohydrates : Fermentation Acetoin, butanediol metabolism 11
  Acetyl-CoA fermentation to Butyrate 17
  Butanol Biosynthesis 12
  Fermentations: Lactate 2
  Fermentations: Mixed acid 10
Carbohydrates : Monosaccharides 2-Ketogluconate Utilization 5
  D-Galacturonate and D-Glucuronate Utilization 8
  D-Sorbitol(D-Glucitol) and L-Sorbose Utilization 1
  D-galactarate, D-glucarate and D-glycerate catabolism 17
  D-gluconate and ketogluconates metabolism 10
  D-ribose utilization 8
  Deoxyribose and Deoxynucleoside Catabolism 4
  Fructose utilization 5
  L-fucose utilization temp 1
  L-rhamnose utilization 1
  Mannose Metabolism 5
Carbohydrates : One-carbon Metabolism One-carbon metabolism by tetrahydropterines 8
  Serine-glyoxylate cycle 34
Carbohydrates : Organic acids Isobutyryl-CoA to Propionyl-CoA Module 11
  Lactate utilization 4
  Methylcitrate cycle 7
  Propionate-CoA to Succinate Module 7
Carbohydrates : Polysaccharides Glycogen metabolism 5
Carbohydrates : Sugar alcohols Di-Inositol-Phosphate biosynthesis 2
  Ethanolamine utilization 5
  Glycerol and Glycerol-3-phosphate Uptake and Utilization 13
  Glycerol fermenation to 1,3-propanediol 1
  Mannitol Utilization 3
  Propanediol utilization 1
  Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization 12
Cell Division and Cell Cycle Bacterial Cytoskeleton 24
  Control of cell elongation - division cycle in Bacilli 1
  Cyanobacterial Circadian Clock 1
  Macromolecular synthesis operon 5
  Two cell division clusters relating to chromosome partitioning 10
Cell Wall and Capsule Peptidoglycan Biosynthesis 28
  UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis 5
Cell Wall and Capsule : Capsular and extracellular polysacchrides Alginate metabolism 14
  CMP-N-acetylneuraminate Biosynthesis 1
  Capsular heptose biosynthesis 4
  Colanic acid biosynthesis 2
  O-Methyl Phosphoramidate Capsule Modification in Campylobacter 3
  Rhamnose containing glycans 13
  Sialic Acid Metabolism 7
  dTDP-rhamnose synthesis 8
Cell Wall and Capsule : Cell wall of Mycobacteria linker unit-arabinogalactan synthesis 12
  mycolic acid synthesis 9
Cell Wall and Capsule : Gram-Negative cell wall components KDO2-Lipid A biosynthesis 14
  LOS core oligosaccharide biosynthesis 7
  Lipid A-Ara4N pathway ( Polymyxin resistance ) 1
  Lipid A modifications 8
  Lipopolysaccharide-related cluster in Alphaproteobacteria 1
Cell Wall and Capsule : Gram-Positive cell wall components Teichoic and lipoteichoic acids biosynthesis 3
Clustering-based subsystems Bacterial Cell Division 26
  Bacterial RNA-metabolizing Zn-dependent hydrolases 9
  CBSS-562.2.peg.5158 SK3 including 1
  Conserved gene cluster associated with Met-tRNA formyltransferase 12
  LMPTP YfkJ cluster 1
  LMPTP YwlE cluster 7
  NusA-TFII Cluster 3
  PA0057 cluster 1
  Putative hemin transporter 2
  Putative sulfate assimilation cluster 3
Clustering-based subsystems : Clustering-based subsystems CBSS-262719.3.peg.410 3
Clustering-based subsystems : Lysine, threonine, methionine, and cysteine YeiH 2
Clustering-based subsystems : proteosome related Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related 4
Cofactors, Vitamins, Prosthetic Groups, Pigments Thiamin biosynthesis 13
Cofactors, Vitamins, Prosthetic Groups, Pigments : Biotin Biotin biosynthesis 11
Cofactors, Vitamins, Prosthetic Groups, Pigments : Coenzyme A Coenzyme A Biosynthesis 10
Cofactors, Vitamins, Prosthetic Groups, Pigments : Folate and pterines Folate Biosynthesis 24
  Molybdenum cofactor biosynthesis 20
  Pterin biosynthesis 5
  p-Aminobenzoyl-Glutamate Utilization 1
Cofactors, Vitamins, Prosthetic Groups, Pigments : Lipoic acid Lipoic acid metabolism 4
Cofactors, Vitamins, Prosthetic Groups, Pigments : NAD and NADP NAD and NADP cofactor biosynthesis global 15
  NAD regulation 7
  PnuC-like transporters 2
Cofactors, Vitamins, Prosthetic Groups, Pigments : Pyridoxine Pyridoxin (Vitamin B6) Biosynthesis 14
Cofactors, Vitamins, Prosthetic Groups, Pigments : Quinone cofactors Coenzyme PQQ synthesis 5
  Menaquinone Biosynthesis via Futalosine 1
  Menaquinone and Phylloquinone Biosynthesis 2
  Plastoquinone Biosynthesis 2
  Pyrroloquinoline Quinone biosynthesis 7
  Tocopherol Biosynthesis 2
  Ubiquinone Biosynthesis 10
Cofactors, Vitamins, Prosthetic Groups, Pigments : Riboflavin, FMN, FAD Flavodoxin 1
  Riboflavin, FMN and FAD metabolism 5
Cofactors, Vitamins, Prosthetic Groups, Pigments : Tetrapyrroles Cobalamin synthesis 13
  Coenzyme B12 biosynthesis 27
  Experimental tye 15
  Heme and Siroheme Biosynthesis 15
DNA Metabolism DNA structural proteins, bacterial 5
  Restriction-Modification System 3
  YcfH 3
DNA Metabolism : DNA recombination RuvABC plus a hypothetical 3
DNA Metabolism : DNA repair 2-phosphoglycolate salvage 4
  DNA Repair Base Excision 16
  DNA repair, UvrABC system 4
  DNA repair, bacterial 23
  DNA repair, bacterial DinG and relatives 2
  DNA repair, bacterial MutL-MutS system 2
  DNA repair, bacterial RecFOR pathway 7
  DNA repair, bacterial UvrD and related helicases 3
DNA Metabolism : DNA replication DNA-replication 29
  DNA replication, archaeal 1
  DNA topoisomerases, Type I, ATP-independent 1
  DNA topoisomerases, Type II, ATP-dependent 4
  Plasmid replication 3
Fatty Acids, Lipids, and Isoprenoids Polyhydroxybutyrate metabolism 19
Fatty Acids, Lipids, and Isoprenoids : Fatty acids Fatty Acid Biosynthesis FASII 17
Fatty Acids, Lipids, and Isoprenoids : Isoprenoids Archaeal lipids 1
  Carotenoids 1
  Isoprenoid Biosynthesis 8
  polyprenyl synthesis 5
Fatty Acids, Lipids, and Isoprenoids : Phospholipids Glycerolipid and Glycerophospholipid Metabolism in Bacteria 46
Fatty Acids, Lipids, and Isoprenoids : Triacylglycerols Triacylglycerol metabolism 1
Iron acquisition and metabolism Campylobacter Iron Metabolism 11
  Heme, hemin uptake and utilization systems in GramPositives 4
  Hemin transport system 11
  Iron acquisition in Vibrio 26
  Transport of Iron 23
Iron acquisition and metabolism : Siderophores Siderophore Enterobactin 4
  Siderophore Pyoverdine 19
Membrane Transport Choline Transport 2
  ECF class transporters 2
  Ton and Tol transport systems 21
  Transport of Molybdenum 4
  Transport of Nickel and Cobalt 8
  Transport of Zinc 6
Membrane Transport : ABC transporters ABC transporter alkylphosphonate (TC 3.A.1.9.1) 20
  ABC transporter branched-chain amino acid (TC 3.A.1.4.1) 19
  ABC transporter dipeptide (TC 3.A.1.5.2) 14
  ABC transporter oligopeptide (TC 3.A.1.5.1) 7
Membrane Transport : Protein and nucleoprotein secretion system, Type IV Type IV pilus 16
  pVir Plasmid of Campylobacter 2
Membrane Transport : Protein secretion system, Type III Type III secretion system orphans 2
Membrane Transport : Protein secretion system, Type VIII (Extracellular nucleation/precipitation pathway, ENP) Curli production 5
Membrane Transport : Protein translocation across cytoplasmic membrane Twin-arginine translocation system 8
Membrane Transport : Sugar Phosphotransferase Systems, PTS Fructose and Mannose Inducible PTS 1
Membrane Transport : Uni- Sym- and Antiporters Na(+) H(+) antiporter 2
  Sodium Hydrogen Antiporter 5
Metabolism of Aromatic Compounds Aromatic Amin Catabolism 4
  Benzoate transport and degradation cluster 2
  Gentisare degradation 5
Metabolism of Aromatic Compounds : Metabolism of central aromatic intermediates Catechol branch of beta-ketoadipate pathway 11
  Central meta-cleavage pathway of aromatic compound degradation 3
  Homogentisate pathway of aromatic compound degradation 8
  N-heterocyclic aromatic compound degradation 7
  Protocatechuate branch of beta-ketoadipate pathway 19
  Salicylate and gentisate catabolism 8
Metabolism of Aromatic Compounds : Peripheral pathways for catabolism of aromatic compounds Benzoate degradation 11
  Chloroaromatic degradation pathway 6
  Phenylpropanoid compound degradation 9
  Quinate degradation 4
  Salicylate ester degradation 2
  n-Phenylalkanoic acid degradation 10
  p-Hydroxybenzoate degradation 2
Miscellaneous Muconate lactonizing enzyme family 1
  YaaA 1
  YbbK 4
  ZZ gjo need homes 18
Miscellaneous : Plant-Prokaryote DOE project Conserved gene cluster possibly involved in RNA metabolism 5
Motility and Chemotaxis Bacterial Chemotaxis 31
Motility and Chemotaxis : Flagellar motility in Prokaryota Flagellar motility 29
  Flagellum 48
  Flagellum in Campylobacter 6
Motility and Chemotaxis : Social motility and nonflagellar swimming in bacteria Rhamnolipids in Pseudomonas 1
Nitrogen Metabolism Allantoin Utilization 8
  Ammonia assimilation 22
  Cyanate hydrolysis 8
  Denitrification 1
  Dissimilatory nitrite reductase 2
  Nitrate and nitrite ammonification 9
  Nitric oxide synthase 2
  Nitrosative stress 2
Nucleosides and Nucleotides Adenosyl nucleosidases 2
  Hydantoin metabolism 9
  Ribonucleotide reduction 3
Nucleosides and Nucleotides : Detoxification Nudix proteins (nucleoside triphosphate hydrolases) 10
Nucleosides and Nucleotides : Purines De Novo Purine Biosynthesis 13
  Purine Utilization 14
  Purine conversions 17
Nucleosides and Nucleotides : Pyrimidines De Novo Pyrimidine Synthesis 11
  Pyrimidine utilization 8
Phages, Prophages, Transposable elements : Bacteriophage structural proteins Phage capsid proteins 3
Phages, Prophages, Transposable elements, Plasmids : Pathogenicity islands Staphylococcal pathogenicity islands SaPI 6
Phages, Prophages, Transposable elements, Plasmids : Transposable elements Tn552 1
Phosphorus Metabolism Alkylphosphonate utilization 2
  High affinity phosphate transporter and control of PHO regulon 13
  Phosphate metabolism 32
  Phosphonate metabolism 4
Potassium metabolism Glutathione-regulated potassium-efflux system and associated functions 5
  Potassium homeostasis 15
Protein Metabolism : Protein biosynthesis Ribosome LSU bacterial 29
  Ribosome SSU bacterial 19
  Ribosome activity modulation 2
  Ribosome biogenesis bacterial 15
  Trans-translation by stalled ribosomes 1
  Translation elongation factor G family 2
  Translation elongation factors eukaryotic and archaeal 1
  Translation initiation factors eukaryotic and archaeal 2
  Universal GTPases 16
  tRNA aminoacylation, Glu and Gln 1
Protein Metabolism : Protein degradation Proteasome bacterial 8
  Protein degradation 5
  Proteolysis in bacteria, ATP-dependent 14
  Putative TldE-TldD proteolytic complex 3
Protein Metabolism : Protein folding GroEL GroES 2
  Peptidyl-prolyl cis-trans isomerase 2
  Periplasmic disulfide interchange 9
  Protein chaperones 10
Protein Metabolism : Protein processing and modification N-linked Glycosylation in Bacteria 5
  Ribosomal protein S12p Asp methylthiotransferase 2
  Ribosomal protein S5p acylation 1
  Signal peptidase 2
Protein Metabolism : Secretion Protein secretion by ABC-type exporters 2
Protein Metabolism : Selenoproteins Glycine reductase, sarcosine reductase and betaine reductase 5
  Selenocysteine metabolism 4
RNA Metabolism : RNA processing and modification ATP-dependent RNA helicases, bacterial 4
  Polyadenylation bacterial 4
  Queuosine-Archaeosine Biosynthesis 22
  RNA processing and degradation, bacterial 6
  Ribonuclease H 2
  Wyeosine-MimG Biosynthesis 4
  tRNA nucleotidyltransferase 1
  tRNA processing 10
RNA Metabolism : Transcription RNA polymerase bacterial 4
  Rrf2 family transcriptional regulators 1
  Transcription factors bacterial 9
  Transcription factors cyanobacterial RpoD-like sigma factors 1
  Transcription initiation, bacterial sigma factors 8
Regulation and Cell signaling CytR regulation 1
  DNA-binding regulatory proteins, strays 25
  Orphan regulatory proteins 15
  Oxygen and light sensor PpaA-PpsR 2
  Pseudomonas quinolone signal PQS 1
  Sex pheromones in Enterococcus faecalis and other Firmicutes 3
  Stringent Response, (p)ppGpp metabolism 2
  Two-component regulatory systems in Campylobacter 6
  cAMP signaling in bacteria 16
Regulation and Cell signaling : Programmed Cell Death and Toxin-antitoxin Systems MazEF toxin-antitoxing (programmed cell death) system 2
  Murein hydrolase regulation and cell death 8
Regulation and Cell signaling : Quorum sensing and biofilm formation Quorum Sensing: Autoinducer-2 Synthesis 1
  Quorum sensing regulation in Pseudomonas 1
Respiration Biogenesis of c-type cytochromes 17
  Biogenesis of cbb3-type cytochrome c oxidases 4
  Biogenesis of cytochrome c oxidases 14
  Formate hydrogenase 9
  Soluble cytochromes and functionally related electron carriers 9
Respiration : ATP synthases F0F1-type ATP synthase 5
Respiration : Electron accepting reactions Anaerobic respiratory reductases 12
  Terminal cytochrome C oxidases 14
  Terminal cytochrome O ubiquinol oxidase 4
  Terminal cytochrome d ubiquinol oxidases 3
  Terminal cytochrome oxidases 7
  Ubiquinone Menaquinone-cytochrome c reductase complexes 3
Respiration : Electron donating reactions Na(+)-translocating NADH-quinone oxidoreductase and rnf-like group of electron transport complexes 4
  Respiratory Complex I 13
  Respiratory dehydrogenases 1 13
  Succinate dehydrogenase 4
Secondary Metabolism : Aromatic amino acids and derivatives Cinnamic Acid Degradation 1
Secondary Metabolism : Biosynthesis of phenylpropanoids Biflavanoid biosynthesis 1
  Phenylpropionate Degradation 1
  Tannin biosynthesis 1
Secondary Metabolism : Plant Hormones Auxin biosynthesis 5
  Auxin degradation 1
Stress Response Bacterial hemoglobins 10
  Flavohaemoglobin 4
  Hfl operon 4
  SigmaB stress responce regulation 2
  Universal stress protein family 11
Stress Response : Acid stress Acid resistance mechanisms 2
Stress Response : Detoxification Glutathione-dependent pathway of formaldehyde detoxification 3
Stress Response : Heat shock Heat shock dnaK gene cluster extended 17
Stress Response : Osmotic stress Choline and Betaine Uptake and Betaine Biosynthesis 30
  Ectoine biosynthesis and regulation 1
Stress Response : Oxidative stress Glutaredoxins 8
  Glutathione: Biosynthesis and gamma-glutamyl cycle 4
  Glutathione: Non-redox reactions 15
  Glutathione: Redox cycle 4
  Oxidative stress 31
  Redox-dependent regulation of nucleus processes 4
  Rubrerythrin 5
Sulfur Metabolism Galactosylceramide and Sulfatide metabolism 1
  Sulfate reduction-associated complexes 1
  Sulfur oxidation 1
  Thioredoxin-disulfide reductase 11
Sulfur Metabolism : Organic sulfur assimilation Alkanesulfonate assimilation 21
  Alkanesulfonates Utilization 12
  Taurine Utilization 9
  Utilization of glutathione as a sulphur source 2
Virulence, Disease and Defense : Detection MLST 6
Virulence, Disease and Defense : Invasion and intracellular resistance Cytolysin and Lipase operon in Vibrio 1
Virulence, Disease and Defense : Resistance to antibiotics and toxic compounds Arsenic resistance 10
  Beta-lactamase 4
  Cobalt-zinc-cadmium resistance 33
  Copper homeostasis 18
  Copper homeostasis: copper tolerance 3
  Mercury resistance operon 1
  Methicillin resistance in Staphylococci 3
  Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria 19
  Multidrug Resistance Efflux Pumps 14
  Multidrug efflux pump in Campylobacter jejuni (CmeABC operon) 5
  Resistance to fluoroquinolones 4