SEED Subsystems in Paraburkholderia sabiae LMG 24235

Subsystems are shown if they have at least one gene assigned to them. Because many roles are assigned to more than one subsystem, the subsystem may not be present even if the gene annotation(s) are correct.

Category Subsystem #Genes
Amino Acids and Derivatives L-2-amino-thiazoline-4-carboxylic acid-Lcysteine conversion 2
Amino Acids and Derivatives : Alanine, serine, and glycine Alanine biosynthesis 6
  Glycine Biosynthesis 9
  Glycine and Serine Utilization 28
  Glycine cleavage system 7
  Serine Biosynthesis 16
Amino Acids and Derivatives : Arginine; urea cycle, polyamines Arginine Biosynthesis extended 15
  Arginine Deiminase Pathway 5
  Arginine and Ornithine Degradation 48
  Polyamine Metabolism 44
  Urea decomposition 20
Amino Acids and Derivatives : Aromatic amino acids and derivatives Aromatic amino acid degradation 32
  Aromatic amino acid interconversions with aryl acids 4
  Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. 8
  Chorismate Synthesis 19
  Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) 15
  Phenylalanine and Tyrosine Branches from Chorismate 5
  Tryptophan synthesis 7
Amino Acids and Derivatives : Branched-chain amino acids Branched-Chain Amino Acid Biosynthesis 41
  HMG CoA Synthesis 18
  Isoleucine degradation 41
  Ketoisovalerate oxidoreductase 3
  Leucine Biosynthesis 9
  Leucine Degradation and HMG-CoA Metabolism 22
  Valine degradation 45
Amino Acids and Derivatives : Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Glutamate dehydrogenases 2
  Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis 59
  Glutamine synthetases 2
Amino Acids and Derivatives : Histidine Metabolism Histidine Biosynthesis 12
  Histidine Degradation 13
Amino Acids and Derivatives : Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis 30
  Lysine Biosynthesis DAP Pathway 7
  Lysine degradation 9
  Methionine Biosynthesis 37
  Methionine Degradation 19
  Methionine Salvage 2
  Threonine anaerobic catabolism gene cluster 4
  Threonine and Homoserine Biosynthesis 36
  Threonine degradation 14
Amino Acids and Derivatives : Proline and 4-hydroxyproline Proline, 4-hydroxyproline uptake and utilization 42
  Proline Synthesis 4
Carbohydrates Lacto-N-Biose I and Galacto-N-Biose Metabolic Pathway 8
Carbohydrates : Aminosugars Chitin and N-acetylglucosamine utilization 8
  N-Acetyl-Galactosamine and Galactosamine Utilization 1
Carbohydrates : CO2 fixation CO2 uptake, carboxysome 6
  Calvin-Benson cycle 19
  Carboxysome 17
  Photorespiration (oxidative C2 cycle) 50
Carbohydrates : Central carbohydrate metabolism Dihydroxyacetone kinases 5
  Entner-Doudoroff Pathway 51
  Glycolate, glyoxylate interconversions 19
  Glycolysis and Gluconeogenesis 20
  Glycolysis and Gluconeogenesis, including Archaeal enzymes 15
  Methylglyoxal Metabolism 37
  Pentose phosphate pathway 17
  Pyruvate Alanine Serine Interconversions 17
  Pyruvate metabolism I: anaplerotic reactions, PEP 18
  Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate 47
  TCA Cycle 30
Carbohydrates : Di- and oligosaccharides Fructooligosaccharides(FOS) and Raffinose Utilization 3
  Lactose and Galactose Uptake and Utilization 15
  Lactose utilization 6
  Maltose and Maltodextrin Utilization 13
  Sucrose utilization 1
  Sucrose utilization Shewanella 1
  Trehalose Biosynthesis 13
  Trehalose Uptake and Utilization 6
Carbohydrates : Fermentation Acetoin, butanediol metabolism 14
  Acetyl-CoA fermentation to Butyrate 66
  Butanol Biosynthesis 34
  Fermentations: Lactate 3
  Fermentations: Mixed acid 11
Carbohydrates : Glycoside hydrolases Predicted carbohydrate hydrolases 2
Carbohydrates : Monosaccharides 2-Ketogluconate Utilization 8
  D-Galacturonate and D-Glucuronate Utilization 20
  D-Sorbitol(D-Glucitol) and L-Sorbose Utilization 2
  D-galactarate, D-glucarate and D-glycerate catabolism 18
  D-galactonate catabolism 6
  D-gluconate and ketogluconates metabolism 10
  D-ribose utilization 35
  Deoxyribose and Deoxynucleoside Catabolism 7
  Fructose utilization 9
  L-Arabinose utilization 15
  L-fucose utilization 1
  L-fucose utilization temp 7
  L-rhamnose utilization 11
  Mannose Metabolism 12
  Xylose utilization 14
Carbohydrates : One-carbon Metabolism Formaldehyde assimilation: Ribulose monophosphate pathway 2
  Methanogenesis 9
  One-carbon metabolism by tetrahydropterines 11
  Serine-glyoxylate cycle 61
Carbohydrates : Organic acids 2-methylcitrate to 2-methylaconitate metabolism cluster 2
  Isobutyryl-CoA to Propionyl-CoA Module 18
  Lactate utilization 10
  Malonate decarboxylase 7
  Methylcitrate cycle 10
  Propionate-CoA to Succinate Module 11
  Propionyl-CoA to Succinyl-CoA Module 5
Carbohydrates : Polysaccharides Glycogen metabolism 9
Carbohydrates : Sugar alcohols Di-Inositol-Phosphate biosynthesis 2
  Erythritol utilization 1
  Ethanolamine utilization 8
  Glycerol and Glycerol-3-phosphate Uptake and Utilization 19
  Inositol catabolism 17
  Mannitol Utilization 6
  Propanediol utilization 2
  Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization 23
Cell Division and Cell Cycle Bacterial Cytoskeleton 34
  Control of cell elongation - division cycle in Bacilli 1
  Cyanobacterial Circadian Clock 2
  Macromolecular synthesis operon 10
  Two cell division clusters relating to chromosome partitioning 18
Cell Wall and Capsule Peptidoglycan Biosynthesis 27
  UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis 11
  YjeE 1
Cell Wall and Capsule : Capsular and extracellular polysacchrides Alginate metabolism 12
  CMP-N-acetylneuraminate Biosynthesis 2
  Capsular heptose biosynthesis 7
  Colanic acid biosynthesis 17
  O-Methyl Phosphoramidate Capsule Modification in Campylobacter 2
  Phosphorylcholine incorporation in LPS 1
  Polysaccharide deacetylases 2
  Rhamnose containing glycans 18
  Sialic Acid Metabolism 18
  dTDP-rhamnose synthesis 9
Cell Wall and Capsule : Cell wall of Mycobacteria linker unit-arabinogalactan synthesis 16
  mycolic acid synthesis 50
Cell Wall and Capsule : Gram-Negative cell wall components KDO2-Lipid A biosynthesis 11
  LOS core oligosaccharide biosynthesis 11
  Lipid A-Ara4N pathway ( Polymyxin resistance ) 8
  Lipopolysaccharide-related cluster in Alphaproteobacteria 1
Cell Wall and Capsule : Gram-Positive cell wall components Teichoic and lipoteichoic acids biosynthesis 5
  Teichuronic acid biosynthesis 4
Clustering-based subsystems Bacterial Cell Division 32
  Bacterial RNA-metabolizing Zn-dependent hydrolases 11
  CBSS-562.2.peg.5158 SK3 including 1
  Conserved gene cluster associated with Met-tRNA formyltransferase 15
  LMPTP YfkJ cluster 5
  LMPTP YwlE cluster 11
  NusA-TFII Cluster 3
  Putative sulfate assimilation cluster 6
Clustering-based subsystems : Clustering-based subsystems CBSS-262719.3.peg.410 2
  Conenzyme B12 related Hypothetical: Clusters with cobST 2
Clustering-based subsystems : Lysine, threonine, methionine, and cysteine YeiH 3
Clustering-based subsystems : Type III secretion system, extended Type III secretion systems, extended 11
Clustering-based subsystems : proteosome related Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related 2
Cofactors, Vitamins, Prosthetic Groups, Pigments Thiamin biosynthesis 13
Cofactors, Vitamins, Prosthetic Groups, Pigments : Biotin Biotin biosynthesis 19
Cofactors, Vitamins, Prosthetic Groups, Pigments : Coenzyme A Coenzyme A Biosynthesis 15
Cofactors, Vitamins, Prosthetic Groups, Pigments : Folate and pterines Folate Biosynthesis 33
  Molybdenum cofactor biosynthesis 21
  Pterin biosynthesis 4
  p-Aminobenzoyl-Glutamate Utilization 5
Cofactors, Vitamins, Prosthetic Groups, Pigments : Lipoic acid Lipoic acid metabolism 4
Cofactors, Vitamins, Prosthetic Groups, Pigments : NAD and NADP NAD and NADP cofactor biosynthesis global 24
  NAD regulation 15
  PnuC-like transporters 1
Cofactors, Vitamins, Prosthetic Groups, Pigments : Pyridoxine Pyridoxin (Vitamin B6) Biosynthesis 18
Cofactors, Vitamins, Prosthetic Groups, Pigments : Quinone cofactors Coenzyme PQQ synthesis 6
  Plastoquinone Biosynthesis 3
  Pyrroloquinoline Quinone biosynthesis 8
  Tocopherol Biosynthesis 3
  Ubiquinone Biosynthesis 16
Cofactors, Vitamins, Prosthetic Groups, Pigments : Riboflavin, FMN, FAD Riboflavin, FMN and FAD metabolism 5
Cofactors, Vitamins, Prosthetic Groups, Pigments : Tetrapyrroles Cobalamin synthesis 15
  Coenzyme B12 biosynthesis 31
  Experimental tye 17
  Heme and Siroheme Biosynthesis 15
DNA Metabolism DNA structural proteins, bacterial 12
  Restriction-Modification System 5
  YcfH 2
DNA Metabolism : DNA recombination RuvABC plus a hypothetical 3
DNA Metabolism : DNA repair 2-phosphoglycolate salvage 5
  DNA Repair Base Excision 18
  DNA repair, UvrABC system 5
  DNA repair, bacterial 29
  DNA repair, bacterial DinG and relatives 2
  DNA repair, bacterial MutL-MutS system 2
  DNA repair, bacterial RecFOR pathway 8
  DNA repair, bacterial UvrD and related helicases 4
DNA Metabolism : DNA replication DNA-replication 35
  DNA replication, archaeal 1
  DNA topoisomerases, Type I, ATP-independent 3
  DNA topoisomerases, Type II, ATP-dependent 4
  Plasmid replication 11
Fatty Acids, Lipids, and Isoprenoids Polyhydroxybutyrate metabolism 48
Fatty Acids, Lipids, and Isoprenoids : Fatty acids Fatty Acid Biosynthesis FASII 62
Fatty Acids, Lipids, and Isoprenoids : Isoprenoids Archaeal lipids 1
  Carotenoids 6
  Isoprenoid Biosynthesis 9
  Polyprenyl Diphosphate Biosynthesis 1
  polyprenyl synthesis 6
Fatty Acids, Lipids, and Isoprenoids : Phospholipids Glycerolipid and Glycerophospholipid Metabolism in Bacteria 64
Iron acquisition and metabolism Campylobacter Iron Metabolism 6
  Heme, hemin uptake and utilization systems in GramPositives 1
  Hemin transport system 6
  Iron acquisition in Vibrio 20
  Transport of Iron 15
Iron acquisition and metabolism : Siderophores Siderophore Pyoverdine 4
Membrane Transport Choline Transport 1
  ECF class transporters 1
  Ton and Tol transport systems 23
  Transport of Manganese 3
  Transport of Molybdenum 8
  Transport of Nickel and Cobalt 2
  Transport of Zinc 6
Membrane Transport : ABC transporters ABC transporter alkylphosphonate (TC 3.A.1.9.1) 7
  ABC transporter branched-chain amino acid (TC 3.A.1.4.1) 22
  ABC transporter dipeptide (TC 3.A.1.5.2) 18
  ABC transporter oligopeptide (TC 3.A.1.5.1) 12
Membrane Transport : Protein and nucleoprotein secretion system, Type IV Type IV pilus 14
  pVir Plasmid of Campylobacter 11
Membrane Transport : Protein secretion system, Type II Widespread colonization island 13
Membrane Transport : Protein translocation across cytoplasmic membrane Twin-arginine translocation system 3
Membrane Transport : Sugar Phosphotransferase Systems, PTS Fructose and Mannose Inducible PTS 2
Membrane Transport : Uni- Sym- and Antiporters Na(+) H(+) antiporter 1
Metabolism of Aromatic Compounds Aromatic Amin Catabolism 12
  Benzoate transport and degradation cluster 11
  Cresol degradation 1
  Gentisare degradation 11
  carbazol degradation cluster 1
Metabolism of Aromatic Compounds : Metabolism of central aromatic intermediates 4-Hydroxyphenylacetic acid catabolic pathway 19
  Catechol branch of beta-ketoadipate pathway 16
  Central meta-cleavage pathway of aromatic compound degradation 13
  Homogentisate pathway of aromatic compound degradation 28
  N-heterocyclic aromatic compound degradation 8
  Protocatechuate branch of beta-ketoadipate pathway 20
  Salicylate and gentisate catabolism 19
Metabolism of Aromatic Compounds : Peripheral pathways for catabolism of aromatic compounds Benzoate degradation 14
  Biphenyl Degradation 2
  Chloroaromatic degradation pathway 8
  Naphtalene and antracene degradation 1
  Phenylpropanoid compound degradation 15
  Quinate degradation 4
  Salicylate ester degradation 5
  Toluene degradation 2
  n-Phenylalkanoic acid degradation 31
  p-Hydroxybenzoate degradation 8
Miscellaneous Luciferases 2
  Muconate lactonizing enzyme family 1
  YaaA 1
  YbbK 4
  ZZ gjo need homes 18
Miscellaneous : Plant-Prokaryote DOE project Conserved gene cluster possibly involved in RNA metabolism 4
Motility and Chemotaxis Bacterial Chemotaxis 79
Motility and Chemotaxis : Flagellar motility in Prokaryota Flagellar motility 47
  Flagellum 77
  Flagellum in Campylobacter 5
Nitrogen Metabolism Allantoin Utilization 10
  Ammonia assimilation 28
  Cyanate hydrolysis 12
  Denitrification 2
  Dissimilatory nitrite reductase 3
  Nitrate and nitrite ammonification 30
  Nitric oxide synthase 4
  Nitrogen fixation 19
  Nitrosative stress 4
Nucleosides and Nucleotides Hydantoin metabolism 14
  Ribonucleotide reduction 4
Nucleosides and Nucleotides : Detoxification Nudix proteins (nucleoside triphosphate hydrolases) 8
Nucleosides and Nucleotides : Purines De Novo Purine Biosynthesis 15
  Purine Utilization 26
  Purine conversions 24
Nucleosides and Nucleotides : Pyrimidines De Novo Pyrimidine Synthesis 12
  Pyrimidine utilization 7
Phages, Prophages, Transposable elements, Plasmids : Pathogenicity islands Staphylococcal pathogenicity islands SaPI 6
Phages, Prophages, Transposable elements, Plasmids : Transposable elements Tn552 1
Phosphorus Metabolism Alkylphosphonate utilization 15
  High affinity phosphate transporter and control of PHO regulon 12
  Phosphate metabolism 38
  Phosphonate metabolism 9
Potassium metabolism Glutathione-regulated potassium-efflux system and associated functions 2
  Potassium homeostasis 16
Protein Metabolism : Protein biosynthesis Ribosome LSU bacterial 29
  Ribosome SSU bacterial 21
  Ribosome activity modulation 1
  Ribosome biogenesis bacterial 11
  Trans-translation by stalled ribosomes 1
  Translation elongation factor G family 3
  Translation elongation factors eukaryotic and archaeal 1
  Translation initiation factors eukaryotic and archaeal 2
  Universal GTPases 16
  tRNA aminoacylation, Glu and Gln 2
Protein Metabolism : Protein degradation Proteasome bacterial 8
  Protein degradation 8
  Proteolysis in bacteria, ATP-dependent 16
  Putative TldE-TldD proteolytic complex 3
Protein Metabolism : Protein folding GroEL GroES 3
  Peptidyl-prolyl cis-trans isomerase 2
  Periplasmic disulfide interchange 4
  Protein chaperones 11
Protein Metabolism : Protein processing and modification N-linked Glycosylation in Bacteria 9
  Ribosomal protein S12p Asp methylthiotransferase 3
  Ribosomal protein S5p acylation 1
  Signal peptidase 3
Protein Metabolism : Selenoproteins Glycine reductase, sarcosine reductase and betaine reductase 10
  Selenocysteine metabolism 4
RNA Metabolism : RNA processing and modification ATP-dependent RNA helicases, bacterial 4
  Polyadenylation bacterial 5
  Queuosine-Archaeosine Biosynthesis 35
  RNA processing and degradation, bacterial 9
  Ribonuclease H 2
  Wyeosine-MimG Biosynthesis 11
  tRNA nucleotidyltransferase 1
  tRNA processing 11
RNA Metabolism : Transcription RNA polymerase bacterial 4
  Rrf2 family transcriptional regulators 4
  Transcription factors bacterial 7
  Transcription factors cyanobacterial RpoD-like sigma factors 2
  Transcription initiation, bacterial sigma factors 16
Regulation and Cell signaling DNA-binding regulatory proteins, strays 24
  Orphan regulatory proteins 21
  Oxygen and light sensor PpaA-PpsR 2
  Sex pheromones in Enterococcus faecalis and other Firmicutes 4
  Stringent Response, (p)ppGpp metabolism 2
  Two-component regulatory systems in Campylobacter 14
  cAMP signaling in bacteria 19
Regulation and Cell signaling : Programmed Cell Death and Toxin-antitoxin Systems MazEF toxin-antitoxing (programmed cell death) system 1
  Murein hydrolase regulation and cell death 4
Regulation and Cell signaling : Quorum sensing and biofilm formation Quorum Sensing: Autoinducer-2 Synthesis 1
Respiration Biogenesis of c-type cytochromes 6
  Biogenesis of cytochrome c oxidases 8
  Carbon monoxide dehydrogenase maturation factors 6
  Formate hydrogenase 14
  Soluble cytochromes and functionally related electron carriers 25
Respiration : ATP synthases F0F1-type ATP synthase 6
Respiration : Electron accepting reactions Anaerobic respiratory reductases 30
  Terminal cytochrome C oxidases 16
  Terminal cytochrome O ubiquinol oxidase 12
  Terminal cytochrome d ubiquinol oxidases 9
  Terminal cytochrome oxidases 21
  Ubiquinone Menaquinone-cytochrome c reductase complexes 4
Respiration : Electron donating reactions CO Dehydrogenase 11
  Formate dehydrogenase 2
  NiFe hydrogenase maturation 4
  Respiratory Complex I 15
  Respiratory dehydrogenases 1 27
  Succinate dehydrogenase 9
Secondary Metabolism : Aromatic amino acids and derivatives Cinnamic Acid Degradation 6
Secondary Metabolism : Biosynthesis of phenylpropanoids Phenylpropionate Degradation 1
Secondary Metabolism : Plant Alkaloids Alkaloid biosynthesis from L-lysine 1
Secondary Metabolism : Plant Hormones Auxin biosynthesis 6
  Auxin degradation 1
Stress Response Bacterial hemoglobins 34
  Flavohaemoglobin 5
  Hfl operon 6
  SigmaB stress responce regulation 5
  Universal stress protein family 3
Stress Response : Detoxification Glutathione-dependent pathway of formaldehyde detoxification 2
Stress Response : Heat shock Heat shock dnaK gene cluster extended 17
Stress Response : Osmotic stress Choline and Betaine Uptake and Betaine Biosynthesis 49
  Ectoine biosynthesis and regulation 2
Stress Response : Oxidative stress Glutaredoxins 8
  Glutathione: Biosynthesis and gamma-glutamyl cycle 8
  Glutathione: Non-redox reactions 24
  Glutathione: Redox cycle 2
  Oxidative stress 53
  Redox-dependent regulation of nucleus processes 6
  Rubrerythrin 8
Sulfur Metabolism Galactosylceramide and Sulfatide metabolism 7
  Sulfur oxidation 7
  Thioredoxin-disulfide reductase 24
Sulfur Metabolism : Organic sulfur assimilation Alkanesulfonate assimilation 37
  Alkanesulfonates Utilization 19
  Taurine Utilization 5
  Utilization of glutathione as a sulphur source 7
Virulence : Type III, Type IV, Type VI, ESAT secretion systems Type 4 secretion and conjugative transfer 28
Virulence, Disease and Defense : Detection MLST 6
Virulence, Disease and Defense : Resistance to antibiotics and toxic compounds Arsenic resistance 2
  Beta-lactamase 4
  Cobalt-zinc-cadmium resistance 20
  Copper homeostasis 6
  Copper homeostasis: copper tolerance 6
  Mercuric reductase 3
  Methicillin resistance in Staphylococci 4
  Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria 29
  Multidrug Resistance Efflux Pumps 38
  Multidrug efflux pump in Campylobacter jejuni (CmeABC operon) 16
  Resistance to fluoroquinolones 4
Virulence, Disease and Defense : Toxins and superantigens Cytolethal distending toxin of Campylobacter jejuni 1