| Role | Gene | Name | |
| 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) | GFF6061 | | |
| ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) | GFF489 | | |
| | GFF6706 | | |
| Adenine phosphoribosyltransferase (EC 2.4.2.7) | No genes | | |
| Adenylate cyclase (EC 4.6.1.1) | GFF1193 | | |
| | GFF184 | | |
| | GFF1848 | | |
| | GFF2261 | | |
| | GFF3347 | | |
| | GFF3423 | | |
| | GFF5410 | | |
| | GFF7165 | | |
| Adenylate/guanylate cyclase (EC 4.6.1.2) | No genes | | |
| CAMP phosphodiesterases class-II:Metallo-beta-lactamase superfamily | GFF5411 | | |
| Cyclic AMP receptor protein | No genes | | |
| ElaA protein | GFF14 | | |
| Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-) | No genes | | |
| Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase | GFF3721 | | |
| | GFF6018 | | |
| Predicted signal-transduction protein containing cAMP-binding and CBS domains | No genes | | |
| Prophage Clp protease-like protein | No genes | | |
| Purine cyclase-related protein | No genes | | |
| Putative Heme-regulated two-component response regulator | No genes | | |
| Putative hemin-binding lipoprotein | No genes | | |
| Putative insecticidal toxin complex | No genes | | |
| adenylate cyclase ExoY | No genes | | |
| anthrax toxin moiety, protective antigen, pagA formerly pag, plasmid pXO1, B. anthracis (M22589, P13423) | No genes | | |
| bifunctional hemolysin-adenylate cyclase precursor | No genes | | |
| cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | GFF2262 | | |
| | GFF3274 | | |
| | GFF5168 | | |
| | GFF6688 | | |
| cAMP-dependent Kef-type K+ transport system | No genes | | |
| calmodulin sensitive adenylate cyclase, edema factor, cya, plasmid pXO1, B. anthracis (M23179, M24074) | No genes | | |
| cyclolysin secretion ATP-binding protein | GFF1930 | | |
| | GFF2197 | | |
| cyclolysin secretion protein | No genes | | |
| cyclolysin-activating lysine-acyltransferase | No genes | | |
| trans-acting positive regulator (Atx A) | No genes | | |
| transcriptional activator AtxA, (pXO1-119) | No genes | | |