SEED Subsystem: Folate Biosynthesis in Hydrogenophaga sp. GW460-11-11-14-LB1

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) GFF3439
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) GFF1613
5-nucleotidase SurE (EC 3.1.3.5) GFF3879
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 GFF2951
Aminodeoxychorismate lyase (EC 4.1.3.38) GFF1215
COG0488: ATPase components of ABC transporters with duplicated ATPase domains GFF1747
Dihydrofolate reductase (EC 1.5.1.3) GFF1166
  GFF5052
  GFF5264
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) GFF1631
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 GFF1245
Dihydropteroate synthase (EC 2.5.1.15) GFF4218
FolM Alternative dihydrofolate reductase 1 GFF1630
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 GFF1240
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) GFF2211
  GFF2574
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) GFF4894
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) GFF4920
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) GFF1215
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) GFF5152
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) GFF5262
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) GFF1363
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB GFF4221

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