SEED Subsystem: Folate Biosynthesis in Mucilaginibacter yixingensis YX-36 DSM 26809

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) ABZR88_RS13920
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) ABZR88_RS21200
5-nucleotidase SurE (EC 3.1.3.5) ABZR88_RS03555
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) ABZR88_RS16625
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) ABZR88_RS03990
COG0488: ATPase components of ABC transporters with duplicated ATPase domains ABZR88_RS20605
Dihydrofolate reductase (EC 1.5.1.3) ABZR88_RS07285
  ABZR88_RS14010
  ABZR88_RS14960
  ABZR88_RS14975
  ABZR88_RS21050
  ABZR88_RS22255
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) No genes
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) ABZR88_RS19875
FolM Alternative dihydrofolate reductase 1 No genes
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 ABZR88_RS16630
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) ABZR88_RS04000
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) ABZR88_RS09400
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) ABZR88_RS15625
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) ABZR88_RS00640
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) ABZR88_RS17025
Thymidylate synthase (EC 2.1.1.45) ABZR88_RS14005
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) ABZR88_RS02960
  ABZR88_RS15455
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB ABZR88_RS04005

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