SEED Subsystem: Folate Biosynthesis in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) GFF90
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) GFF3012
5-nucleotidase SurE (EC 3.1.3.5) No genes
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) GFF3378
COG0488: ATPase components of ABC transporters with duplicated ATPase domains GFF3240
Dihydrofolate reductase (EC 1.5.1.3) GFF193
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) GFF3172
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) GFF2917
FolM Alternative dihydrofolate reductase 1 No genes
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 GFF3785
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) GFF2391
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) GFF4447
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) GFF3709
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) GFF2826
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) GFF2447
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) GFF2750
Thymidylate synthase (EC 2.1.1.45) GFF1309
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) GFF1083
  GFF2196
  GFF2333
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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