| Role | Gene | Name | |
|---|
| Antiphagocytic M protein | No genes | | |
| C3 family ADP-ribosyltransferase (EC 2.4.2.-) | No genes | | |
| C5a peptidase (EC 3.4.21.-) | No genes | | |
| CAMP factor | No genes | | |
| Collagen-like surface protein | No genes | | |
| D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13) | EX28DRAFT_1958 | | |
| D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13) | No genes | | |
| Fibrinogen-binding protein | No genes | | |
| Fibronectin-binding protein | No genes | | |
| Hyaluronan synthase (EC 2.4.1.212) | No genes | | |
| Hyaluronate lyase precursor (EC 4.2.2.1) | No genes | | |
| Immunoglobulin G-endopeptidase (IdeS) | No genes | | |
| Mitogenic factor 2 | No genes | | |
| Mitogenic factor 3 | No genes | | |
| Mitogenic factor 4 | No genes | | |
| Nicotine adenine dinucleotide glycohydrolase (NADGH) (EC 3.2.2.5) | No genes | | |
| Plasmin(ogen) receptor | No genes | | |
| Protein G-related alpha 2 macroglobulin-binding protein (GRAB) | No genes | | |
| Secreted Endo-beta-N-acetylglucosaminidase (EndoS) | No genes | | |
| Serine endopeptidase ScpC (EC 3.4.21.-) | No genes | | |
| Serum opacity factor | No genes | | |
| Streptococcal inhibitor of complement (SIC) | No genes | | |
| Streptococcal mitogenic exotoxin Z (SmeZ) | No genes | | |
| Streptococcal pyrogenic exotoxin A (SpeA) | No genes | | |
| Streptococcal pyrogenic exotoxin B (SpeB) | No genes | | |
| Streptococcal pyrogenic exotoxin C (SpeC) | No genes | | |
| Streptococcal pyrogenic exotoxin G (SpeG) | No genes | | |
| Streptococcal pyrogenic exotoxin G (SpeG) fragment | No genes | | |
| Streptococcal pyrogenic exotoxin H (SpeH) | No genes | | |
| Streptococcal pyrogenic exotoxin I (SpeI) | No genes | | |
| Streptococcal pyrogenic exotoxin J (SpeJ) | No genes | | |
| Streptococcal pyrogenic exotoxin J (SpeJ) fragment | No genes | | |
| Streptococcal pyrogenic exotoxin K (SpeK) | No genes | | |
| Streptococcal pyrogenic exotoxin L (SpeL) | No genes | | |
| Streptococcal pyrogenic exotoxin M (SpeM) | No genes | | |
| Streptococcal superantigen A (SSA) | No genes | | |
| Streptodornase B | No genes | | |
| Streptodornase D | No genes | | |
| Streptokinase | No genes | | |
| Streptolysin O | No genes | | |
| Streptolysin S precursor (SagA) | No genes | | |