SEED Subsystem: Isoprenoid Biosynthesis in Escherichia coli ECOR38

Experiments:

Role Gene Name  
1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267) HEPCGN_08150 ispC
1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7) HEPCGN_07050 dxs
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1) HEPCGN_20840 ispG
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) HEPCGN_19650 ispF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) HEPCGN_19645 ispD
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) HEPCGN_24900 ispE
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2) HEPCGN_08950 ispH
Acetyl-CoA acetyltransferase (EC 2.3.1.9) HEPCGN_19595 yqeF
  HEPCGN_22410 atoB
Candidate gene for the hypothesized phosphomevalonate decarboxylase No genes
Dimethylallyltransferase (EC 2.5.1.1) No genes
Diphosphomevalonate decarboxylase (EC 4.1.1.33) No genes
Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) No genes
Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34) No genes
Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) No genes
Isopentenyl phosphate kinase No genes
Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) HEPCGN_18885 idi
Isopentenyl-diphosphate delta-isomerase, FMN-dependent (EC 5.3.3.2) No genes
Mevalonate kinase (EC 2.7.1.36) No genes
Phosphomevalonate kinase (EC 2.7.4.2) No genes
Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31) No genes

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