SEED Subsystem: Coenzyme B12 biosynthesis in Caulobacter crescentus NA1000 Δfur

Experiments:

Role Gene Name  
5,6-dimethylbenzimidazole synthase, flavin destructase family No genes
ATPase component CbiO of energizing module of cobalt ECF transporter No genes
Additional lipoprotein component of predicted cobalamin ECF transporter No genes
Additional substrate-specific component CbiN of cobalt ECF transporter No genes
Adenosylcobinamide amidohydrolase (EC 3.5.1.90) No genes
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) No genes
Adenosylcobinamide-phosphate synthase No genes
Aerobic cobaltochelatase CobS subunit (EC 6.6.1.2) CCNA_03115
Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) CCNA_00708
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) No genes
CblX, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase CCNA_01366
CblY, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase CCNA_01365
CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
ChlD component of cobalt chelatase involved in B12 biosynthesis No genes
ChlI component of cobalt chelatase involved in B12 biosynthesis No genes
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) No genes
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) No genes
Cob(II)alamin reductase No genes
CobN component of cobalt chelatase involved in B12 biosynthesis No genes
CobW GTPase involved in cobalt insertion for B12 biosynthesis No genes
Cobalamin biosynthesis protein CbiG No genes
Cobalamin biosynthesis protein CobG No genes
Cobalamin synthase No genes
Cobalamine-related hypothetical metal-binding protein CrdX No genes
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) No genes
Cobalt-precorrin-3b C17-methyltransferase No genes
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) No genes
Cobalt-precorrin-6 synthase, anaerobic No genes
Cobalt-precorrin-6x reductase (EC 1.3.1.54) No genes
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) No genes
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) No genes
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) CCNA_02098
Cobyric acid synthase No genes
Cobyrinic acid A,C-diamide synthase No genes
Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter No genes
HoxN/HupN/NixA family cobalt transporter No genes
HupE-UreJ family cobalt transporter No genes
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) No genes
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) CCNA_01367
Optional hypothetical component of the B12 transporter BtuM No genes
Optional hypothetical component of the B12 transporter BtuN No genes
Outer membrane vitamin B12 receptor BtuB CCNA_01826
  CCNA_02277
  CCNA_02777
Precorrin-6A synthase (EC 2.1.1.152) No genes
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) No genes
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) No genes
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis No genes
Predicted cobalt ABC transporter periplasmic component No genes
Predicted cobalt transporter CbtA No genes
Predicted cobalt transporter CbtC No genes
Predicted cobalt transporter in Bacteroides_Porphyromonas No genes
Predicted cobalt transporter in Mycobacteria No genes
Predicted cobalt transporter in Thermoplasma No genes
Predicted cobalt transporter in sulfate-reducing delta-proteobacteria No genes
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis No genes
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) No genes
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) No genes
Substrate-specific component CbiM of cobalt ECF transporter No genes
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole No genes
Substrate-specific component CbrT of predicted cobalamin ECF transporter No genes
Threonine kinase in B12 biosynthesis No genes
Transmembrane component CbiQ of energizing module of cobalt ECF transporter No genes
Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter No genes
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) CCNA_00654
  CCNA_01175
Vitamin B12 ABC transporter, ATPase component BtuD CCNA_01251
Vitamin B12 ABC transporter, B12-binding component BtuF CCNA_01249
Vitamin B12 ABC transporter, permease component BtuC CCNA_01250

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