SEED Subsystem: Coenzyme B12 biosynthesis in Azospirillum sp. SherDot2

Experiments:

Role Gene Name  
5,6-dimethylbenzimidazole synthase, flavin destructase family No genes
ATPase component CbiO of energizing module of cobalt ECF transporter No genes
Additional lipoprotein component of predicted cobalamin ECF transporter No genes
Additional substrate-specific component CbiN of cobalt ECF transporter No genes
Adenosylcobinamide amidohydrolase (EC 3.5.1.90) No genes
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) MPMX19_01023
Adenosylcobinamide-phosphate synthase No genes
Aerobic cobaltochelatase CobS subunit (EC 6.6.1.2) MPMX19_02632
Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) MPMX19_02630
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) MPMX19_02009
CblX, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblY, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
ChlD component of cobalt chelatase involved in B12 biosynthesis No genes
ChlI component of cobalt chelatase involved in B12 biosynthesis No genes
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) MPMX19_01024
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) No genes
Cob(II)alamin reductase No genes
CobN component of cobalt chelatase involved in B12 biosynthesis MPMX19_05573
CobW GTPase involved in cobalt insertion for B12 biosynthesis MPMX19_05574
Cobalamin biosynthesis protein CbiG MPMX19_05566
Cobalamin biosynthesis protein CobG MPMX19_05572
Cobalamin synthase MPMX19_02008
Cobalamine-related hypothetical metal-binding protein CrdX No genes
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) MPMX19_05570
Cobalt-precorrin-3b C17-methyltransferase MPMX19_05566
  MPMX19_05569
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) MPMX19_05565
Cobalt-precorrin-6 synthase, anaerobic MPMX19_05564
Cobalt-precorrin-6x reductase (EC 1.3.1.54) MPMX19_05568
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) MPMX19_05567
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) MPMX19_05567
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) MPMX19_05571
Cobyric acid synthase No genes
Cobyrinic acid A,C-diamide synthase MPMX19_05562
Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter No genes
HoxN/HupN/NixA family cobalt transporter No genes
HupE-UreJ family cobalt transporter No genes
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) MPMX19_01265
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) MPMX19_00312
Optional hypothetical component of the B12 transporter BtuM No genes
Optional hypothetical component of the B12 transporter BtuN No genes
Outer membrane vitamin B12 receptor BtuB MPMX19_05166
Precorrin-6A synthase (EC 2.1.1.152) No genes
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) No genes
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) No genes
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis No genes
Predicted cobalt ABC transporter periplasmic component No genes
Predicted cobalt transporter CbtA MPMX19_05575
Predicted cobalt transporter CbtC No genes
Predicted cobalt transporter in Bacteroides_Porphyromonas No genes
Predicted cobalt transporter in Mycobacteria No genes
Predicted cobalt transporter in Thermoplasma No genes
Predicted cobalt transporter in sulfate-reducing delta-proteobacteria No genes
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis No genes
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) No genes
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) No genes
Substrate-specific component CbiM of cobalt ECF transporter No genes
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole No genes
Substrate-specific component CbrT of predicted cobalamin ECF transporter No genes
Threonine kinase in B12 biosynthesis MPMX19_06279
Transmembrane component CbiQ of energizing module of cobalt ECF transporter No genes
Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter No genes
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) MPMX19_05563
  MPMX19_05929
Vitamin B12 ABC transporter, ATPase component BtuD MPMX19_05170
Vitamin B12 ABC transporter, B12-binding component BtuF No genes
Vitamin B12 ABC transporter, permease component BtuC MPMX19_05164

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