SEED Subsystem: Folate Biosynthesis in Agrobacterium fabrum C58

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Atu1354
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Atu3731
5-nucleotidase SurE (EC 3.1.3.5) Atu1702
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) Atu3766
COG0488: ATPase components of ABC transporters with duplicated ATPase domains No genes
Dihydrofolate reductase (EC 1.5.1.3) Atu1214
  Atu2046
  Atu4585
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) Atu1353
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) Atu1352
FolM Alternative dihydrofolate reductase 1 Atu1130
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 Atu1749
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) Atu0367
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Atu0589
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Atu3369
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) Atu1676
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) Atu1165
  Atu4314
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) Atu2282
Thymidylate synthase (EC 2.1.1.45) Atu2047
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) Atu4464
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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