SEED Subsystem: Coenzyme A Biosynthesis in Escherichia coli BW25113

Role	Gene	Name	vcDART vector transformation; liquid outgrowth assay
2-dehydropantoate 2-reductase (EC 1.1.1.169)	b0425	panE	-0.1
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)	b0134	panB	+0.3
Aspartate 1-decarboxylase (EC 4.1.1.11)	b0131	panD	+0.3
Dephospho-CoA kinase (EC 2.7.1.24)	b0103	coaE	N.D.
Dephospho-CoA kinase archaeal, predicted (EC 2.7.1.24)	No genes
Ketol-acid reductoisomerase (EC 1.1.1.86)	b3774	ilvC	-0.0
Pantoate kinase, archaeal (EC 2.7.1.-)	No genes
Pantoate--beta-alanine ligase (EC 6.3.2.1)	b0133	panC	+0.6
Pantothenate kinase (EC 2.7.1.33)	b3974	coaA	N.D.
Pantothenate kinase type II, eukaryotic (EC 2.7.1.33)	No genes
Pantothenate kinase type III, CoaX-like (EC 2.7.1.33)	No genes
Pantothenate:Na+ symporter (TC 2.A.21.1.1)	b3258	panF	+1.7
Phosphopantetheine adenylyltransferase (EC 2.7.7.3)	b3634	coaD	N.D.
Phosphopantetheine adenylyltransferase, type II eukaryotic (EC 2.7.7.3)	No genes
Phosphopantothenate synthetase, archaeal	No genes
Phosphopantothenoylcysteine decarboxylase (EC 4.1.1.36)	b3639	dfp	N.D.
Phosphopantothenoylcysteine synthetase (EC 6.3.2.5)	b3639	dfp	N.D.
Substrate-specific component PanT of predicted pantothenate ECF transporter	No genes