SEED Subsystem: Folate Biosynthesis in Rhodanobacter sp000427505 FW510-R12

Experiments:

Role Gene Name defined media with L-Serine  
⨯
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) LRK53_RS02845 -0.9
  LRK53_RS13505 N.D.
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) LRK53_RS16890 -0.4
5-nucleotidase SurE (EC 3.1.3.5) LRK53_RS12270 -0.1
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) LRK53_RS08905 +0.2
COG0488: ATPase components of ABC transporters with duplicated ATPase domains LRK53_RS16475 -0.0
Dihydrofolate reductase (EC 1.5.1.3) LRK53_RS05910 N.D.
  LRK53_RS16105 -0.3
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) LRK53_RS02840 N.D.
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) LRK53_RS11520 N.D.
FolM Alternative dihydrofolate reductase 1 LRK53_RS01100 -1.3
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 LRK53_RS00645 -0.6
  LRK53_RS01455 N.D.
GTP cyclohydrolase I (EC 3.5.4.16) type 2 LRK53_RS07495 N.D.
Methionyl-tRNA formyltransferase (EC 2.1.2.9) LRK53_RS02910 N.D.
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) LRK53_RS11165 N.D.
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) LRK53_RS08900 -0.0
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) LRK53_RS05390 -2.3
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) LRK53_RS03590 +0.1
Thymidylate synthase (EC 2.1.1.45) LRK53_RS05905 -0.2
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) LRK53_RS18075 +0.2
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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