| Role | Gene | Name | L-Lysine (N) | |
|---|
| | | ⨯ | |
| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) | Echvi_2784 | | N.D. | |
| 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) | Echvi_1511 | | -0.3 | |
| 5-nucleotidase SurE (EC 3.1.3.5) | Echvi_3388 | | -0.1 | |
| 6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) | Echvi_2135 | | -1.7 | |
| | Echvi_4637 | | -1.5 | |
| ATPase component of general energizing module of ECF transporters | No genes | | | |
| Alternative Folylglutamate Synthase | No genes | | | |
| Alternative dihydrofolate reductase 2 | No genes | | | |
| Alternative dihydrofolate reductase 3 | No genes | | | |
| Aminodeoxychorismate lyase (EC 4.1.3.38) | Echvi_2832 | | +0.4 | |
| COG0488: ATPase components of ABC transporters with duplicated ATPase domains | Echvi_1796 | | +2.5 | |
| Dihydrofolate reductase (EC 1.5.1.3) | Echvi_1421 | | -0.2 | |
| | Echvi_2448 | | N.D. | |
| | Echvi_2684 | | +0.0 | |
| | Echvi_4291 | | -0.0 | |
| | Echvi_4303 | | -0.1 | |
| Dihydrofolate synthase (EC 6.3.2.12) | Echvi_3482 | | N.D. | |
| Dihydroneopterin aldolase (EC 4.1.2.25) | Echvi_0107 | | N.D. | |
| Dihydroneopterin triphosphate epimerase | No genes | | | |
| Dihydroneopterin triphosphate pyrophosphohydolase | Echvi_0501 | | -0.1 | |
| Dihydroneopterin triphosphate pyrophosphohydolase type 2 | No genes | | | |
| Dihydropteroate synthase (EC 2.5.1.15) | Echvi_0143 | | N.D. | |
| FolM Alternative dihydrofolate reductase 1 | No genes | | | |
| Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) | No genes | | | |
| Folate transporter 3 | No genes | | | |
| Folylpolyglutamate synthase (EC 6.3.2.17) | Echvi_3482 | | N.D. | |
| Formate--tetrahydrofolate ligase (EC 6.3.4.3) | No genes | | | |
| GTP cyclohydrolase I (EC 3.5.4.16) type 1 | Echvi_2136 | | N.D. | |
| GTP cyclohydrolase I (EC 3.5.4.16) type 2 | No genes | | | |
| Methionyl-tRNA formyltransferase (EC 2.1.2.9) | Echvi_2450 | | N.D. | |
| Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | Echvi_4643 | | N.D. | |
| Non functional Dihydropteroate synthase 2 | No genes | | | |
| Nucleoside triphosphate pyrophosphohydrolase MazG | No genes | | | |
| Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) | No genes | | | |
| Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) | Echvi_2333 | | +0.1 | |
| PqqC-like protein | No genes | | | |
| Putative DHNTP pyrophosphatase | No genes | | | |
| Related to Dihydropteroate synthase | No genes | | | |
| Serine hydroxymethyltransferase (EC 2.1.2.1) | Echvi_1188 | | -4.6 | |
| Substrate-specific component FolT of folate ECF transporter | No genes | | | |
| Thymidine kinase (EC 2.7.1.21) | Echvi_1460 | | -0.6 | |
| Thymidylate synthase (EC 2.1.1.45) | Echvi_2831 | | N.D. | |
| Thymidylate synthase thyX (EC 2.1.1.-) | No genes | | | |
| Transaldolase (EC 2.2.1.2) | Echvi_2500 | | -3.8 | |
| Transmembrane component of general energizing module of ECF transporters | No genes | | | |
| Xanthosine/inosine triphosphate pyrophosphatase | No genes | | | |
| alternate gene name: yzbB | Echvi_2040 | | +0.0 | |
| | Echvi_2451 | | +0.2 | |