SEED Subsystem: De Novo Pyrimidine Synthesis in Escherichia coli BW25113

Experiments:

Role Gene Name protonated control  
⨯
Aspartate carbamoyltransferase (EC 2.1.3.2) b4245 pyrB -3.9
Aspartate carbamoyltransferase regulatory chain (PyrI) b4244 pyrI -1.4
Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) b0033 carB -5.4
Carbamoyl-phosphate synthase large chain A (EC 6.3.5.5) No genes
Carbamoyl-phosphate synthase large chain B (EC 6.3.5.5) No genes
Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) b0032 carA -5.5
Dihydroorotase (EC 3.5.2.3) b1062 pyrC -4.3
Dihydroorotate dehydrogenase (EC 1.3.3.1) b0945 pyrD -5.1
Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1) No genes
Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1) No genes
Orotate phosphoribosyltransferase (EC 2.4.2.10) b3642 pyrE -4.2
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) b1281 pyrF -3.5
Pyrimidine operon regulatory protein PyrR No genes
Uracil permease b1006 ycdG -0.0
  b2497 uraA -0.3
Uracil phosphoribosyltransferase (EC 2.4.2.9) b2498 upp +0.7

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Or view this subsystem at the SEED (slow)