SEED Subsystem: Isoleucine degradation in Pseudomonas simiae WCS417

Experiments:

Role Gene Name L-Valine (C)  
⨯
3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) PS417_07575 -0.6
  PS417_21215 -0.2
3-ketoacyl-CoA thiolase (EC 2.3.1.16) PS417_13855 -1.1
  PS417_19210 +0.4
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) No genes
Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2) No genes
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) No genes
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) PS417_17545 -2.7
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) PS417_17550 -1.5
Branched-chain amino acid aminotransferase (EC 2.6.1.42) PS417_17565 -7.4
Butyrate kinase (EC 2.7.2.7) No genes
Butyryl-CoA dehydrogenase (EC 1.3.99.2) PS417_09185 -0.2
  PS417_10685 -0.2
  PS417_13840 -3.1
  PS417_13850 -0.4
  PS417_14420 +0.5
  PS417_15190 -0.1
  PS417_16045 +0.2
  PS417_20795 -0.1
  PS417_04135 +0.2
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) PS417_17555 N.D.
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4) PS417_17560 -4.5
Enoyl-CoA hydratase (EC 4.2.1.17) PS417_07030 -0.3
  PS417_07575 -0.6
  PS417_08535 -0.5
  PS417_10680 -0.6
  PS417_11445 -0.4
  PS417_22625 +0.2
Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) PS417_21215 -0.2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-) No genes
Predicted transcriptional regulator of leucine degradation pathway, MerR family No genes
Probable acyl-CoA dehydrogenase (EC 1.3.99.3) PS417_13860 N.D.
  PS417_14930 +0.4
Transcriptional regulator BkdR of isoleucine and valine catabolism operon PS417_17540 N.D.
phosphotransbutyrylase (EC 2.3.1.19) No genes

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