SEED Subsystem: Peptidoglycan Biosynthesis in Escherichia coli ECRC98

Experiments:

Role Gene Name WM_EV240  
⨯
Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) JDDGAC_14260 ftsI N.D.
D-alanine--D-alanine ligase (EC 6.3.2.4) JDDGAC_12290 ddlA +0.1
  JDDGAC_14220 ddlB -0.4
D-alanine--D-alanine ligase A (EC 6.3.2.4) No genes
D-alanine--D-alanine ligase B (EC 6.3.2.4) No genes
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) JDDGAC_09675 dacC +0.6
  JDDGAC_11025 dacA +1.5
  JDDGAC_21665 dacB +0.4
  JDDGAC_29140 dacD +0.2
Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) JDDGAC_18465 glmU N.D.
Glutamate racemase (EC 5.1.1.3) JDDGAC_17150 murI N.D.
Glutamine synthetase type I (EC 6.3.1.2) JDDGAC_17725 glnA N.D.
Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) No genes
Glutamine synthetase type III, GlnN (EC 6.3.1.2) No genes
Glutamine synthetase, clostridia type (EC 6.3.1.2) No genes
Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) No genes
Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) JDDGAC_24360 mltB -0.3
Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) JDDGAC_21535 mtgA +0.1
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) JDDGAC_13920 mrcB -2.0
  JDDGAC_20710 mrcA -0.1
Murein-DD-endopeptidase (EC 3.4.99.-) JDDGAC_27600 pbpG +0.7
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) JDDGAC_18465 glmU N.D.
N-acetylglucosamine-1-phosphate uridyltransferase eukaryotic (EC 2.7.7.23) No genes
Penicillin-binding protein 2 (PBP-2) JDDGAC_11010 mrdA N.D.
Penicillin-binding protein 4 precursor No genes
Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase No genes
Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C JDDGAC_25355 pbpC -0.2
Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) JDDGAC_14245 mraY N.D.
Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) No genes
Rare lipoprotein A precursor JDDGAC_11020 rlpA +0.3
Rod shape-determining protein RodA JDDGAC_11015 mrdB N.D.
UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) JDDGAC_17120 murB N.D.
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) JDDGAC_21630 murA N.D.
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) JDDGAC_14230 murG N.D.
UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) JDDGAC_14225 murC N.D.
UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) JDDGAC_14240 murD N.D.
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) JDDGAC_14255 murE N.D.
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) JDDGAC_14250 murF N.D.

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