SEED Subsystem: Peptidoglycan Biosynthesis in Escherichia coli BW25113

Experiments:

Role Gene Name Cephalothin 0.01 mg/ml  
Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129) b0084 ftsI N.D.
D-alanine--D-alanine ligase (EC 6.3.2.4) No genes
D-alanine--D-alanine ligase A (EC 6.3.2.4) No genes
D-alanine--D-alanine ligase B (EC 6.3.2.4) No genes
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) b0632 dacA -2.4
  b0839 dacC -0.2
  b2010 dacD +0.3
  b3182 dacB -0.7
Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) b3730 glmU N.D.
Glutamate racemase (EC 5.1.1.3) b3967 murI N.D.
Glutamine synthetase type I (EC 6.3.1.2) b3870 glnA -0.0
Glutamine synthetase type II, eukaryotic (EC 6.3.1.2) No genes
Glutamine synthetase type III, GlnN (EC 6.3.1.2) No genes
Glutamine synthetase, clostridia type (EC 6.3.1.2) No genes
Membrane-bound lytic murein transglycosylase B (EC 3.2.1.-) No genes
Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) b2701 mltB -2.1
Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-) b3208 mtgA +0.3
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) b0149 mrcB -2.7
  b3396 mrcA -0.1
Murein-DD-endopeptidase (EC 3.4.99.-) b2134 pbpG +0.7
N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) b3730 glmU N.D.
N-acetylglucosamine-1-phosphate uridyltransferase eukaryotic (EC 2.7.7.23) No genes
Penicillin-binding protein 2 (PBP-2) b0635 mrdA N.D.
Penicillin-binding protein 4 precursor No genes
Penicillin-binding protein PBP2a, methicillin resistance determinant MecA, transpeptidase No genes
Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C b2519 pbpC -0.2
Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) b0087 mraY N.D.
Putative glutamine synthetase, Rickettsiales type (EC 6.3.1.2) No genes
Rare lipoprotein A precursor b0633 rlpA -1.5
Rod shape-determining protein RodA b0634 mrdB N.D.
UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158) b3972 murB N.D.
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) b3189 murA N.D.
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227) b0090 murG N.D.
UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) b0091 murC N.D.
UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) b0088 murD -1.1
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) b0085 murE N.D.
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (EC 6.3.2.10) b0086 murF N.D.

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