SEED Subsystem: Coenzyme B12 biosynthesis in Pseudomonas putida KT2440

Experiments:

Role Gene Name 3-methyl-1-butanol (C)  
5,6-dimethylbenzimidazole synthase, flavin destructase family No genes
ATPase component CbiO of energizing module of cobalt ECF transporter No genes
Additional lipoprotein component of predicted cobalamin ECF transporter No genes
Additional substrate-specific component CbiN of cobalt ECF transporter No genes
Adenosylcobinamide amidohydrolase (EC 3.5.1.90) No genes
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) PP_1678 -1.6
Adenosylcobinamide-phosphate synthase No genes
Aerobic cobaltochelatase CobS subunit (EC 6.6.1.2) No genes
Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) No genes
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) PP_1680 N.D.
CblX, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblY, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
ChlD component of cobalt chelatase involved in B12 biosynthesis PP_3505 -2.6
ChlI component of cobalt chelatase involved in B12 biosynthesis PP_3506 -1.9
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) PP_1672 -1.9
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) No genes
Cob(II)alamin reductase No genes
CobN component of cobalt chelatase involved in B12 biosynthesis PP_3507 -1.7
CobW GTPase involved in cobalt insertion for B12 biosynthesis PP_3508 -1.4
Cobalamin biosynthesis protein CbiG PP_4826 -2.2
Cobalamin biosynthesis protein CobG PP_4829 -1.1
Cobalamin synthase No genes
Cobalamine-related hypothetical metal-binding protein CrdX No genes
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) PP_4827 -1.9
Cobalt-precorrin-3b C17-methyltransferase PP_3409 -1.4
  PP_4826 -2.2
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) PP_3410 N.D.
Cobalt-precorrin-6 synthase, anaerobic PP_4831 -1.5
Cobalt-precorrin-6x reductase (EC 1.3.1.54) PP_4832 -1.4
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) PP_4830 -1.7
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) PP_4830 -1.7
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) PP_4828 -0.3
Cobyric acid synthase No genes
Cobyrinic acid A,C-diamide synthase PP_1673 -2.0
Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter No genes
HoxN/HupN/NixA family cobalt transporter No genes
HupE-UreJ family cobalt transporter No genes
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) PP_1676 -1.7
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) PP_1679 -1.3
Optional hypothetical component of the B12 transporter BtuM No genes
Optional hypothetical component of the B12 transporter BtuN PP_3331 -0.1
Outer membrane vitamin B12 receptor BtuB PP_0525 +0.0
  PP_3330 -0.0
Precorrin-6A synthase (EC 2.1.1.152) PP_3763 -0.3
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) No genes
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) No genes
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis No genes
Predicted cobalt ABC transporter periplasmic component No genes
Predicted cobalt transporter CbtA PP_3408 -0.3
Predicted cobalt transporter CbtC No genes
Predicted cobalt transporter in Bacteroides_Porphyromonas No genes
Predicted cobalt transporter in Mycobacteria No genes
Predicted cobalt transporter in Thermoplasma No genes
Predicted cobalt transporter in sulfate-reducing delta-proteobacteria No genes
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis No genes
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) No genes
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) No genes
Substrate-specific component CbiM of cobalt ECF transporter No genes
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole No genes
Substrate-specific component CbrT of predicted cobalamin ECF transporter No genes
Threonine kinase in B12 biosynthesis No genes
Transmembrane component CbiQ of energizing module of cobalt ECF transporter No genes
Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter No genes
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) PP_2090 -0.3
  PP_3999 -4.0
Vitamin B12 ABC transporter, ATPase component BtuD No genes
Vitamin B12 ABC transporter, B12-binding component BtuF PP_0524 -0.3
Vitamin B12 ABC transporter, permease component BtuC No genes

Or select organism:

Or view this subsystem at the SEED (slow)